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The map label for this gene is nuoB1

Identifier: 116622878

GI number: 116622878

Start: 4800731

End: 4801297

Strand: Direct

Name: nuoB1

Synonym: Acid_3779

Alternate gene names: 116622878

Gene position: 4800731-4801297 (Clockwise)

Preceding gene: 116622877

Following gene: 116622879

Centisome position: 48.17

GC content: 57.5

Gene sequence:

>567_bases
ATGTCGTCCTTTATTCAGAACCAGTTCGAACAGAATTTCATCACCACCAACGTGGATCATGTGTTCAACTGGGCGCGCAA
ATCGGCGCTTTGGCCGCTCACTTTCGGGTTGGCCTGCTGTGCGATCGAGATGATCGCATCCAGCACTTCGCGCTTCGATA
TTGCGCGTTTTGGCGCGGAGGTCTTCCGGCCGAGCCCGCGGCAGAGCGATCTGATGATCGTCGCCGGCACGGTGACCTTG
AAGATGGCGCCCGTTTTGAAGCGCATCTGGGACCAGATGCCCGACCCGAAGTGGTGCATCTCCATGGGTGCCTGCTCCAG
CGTGGGTGGGCCATTCAATACGTACGCCGTGTTGCAGGGCGTGGACAAGATCGTCCCGGTGGACGTTTATGTGACGGGAT
GTCCGCCCCGTCCCGAGAATCTCTTTTACGCGCTGCTTAAATTGCAGGACAAGATCGATACCATGACCACGCTGGTGAAG
CGCCCCACCGAAGTGCGGTTGGACGAGACCATGCTGGAAGAGTTCAAACAGCAGATCCGCATCGCCCAGATTCAGAATCC
CGCATAA

Upstream 100 bases:

>100_bases
GCGCCGCGCCACCCGGGTCAACCCGATCGACGCATTGCGGTTCGAATAGCATTTTCAATGTGCCGTGATAGAATGCGGGT
TAACCAACAAGGAGAGCTGG

Downstream 100 bases:

>100_bases
ATCGTGTTCTACCGGGACCCGCAACATATCTACCGCGTTACTGAATTGGATGCGCTGCCTTGGCTCGTCCATGGATTCGG
CACGCGGCTGGCCGATATTC

Product: NADH-quinone oxidoreductase subunit B

Products: NA

Alternate protein names: NADH dehydrogenase I subunit B 1; NDH-1 subunit B 1

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSSFIQNQFEQNFITTNVDHVFNWARKSALWPLTFGLACCAIEMIASSTSRFDIARFGAEVFRPSPRQSDLMIVAGTVTL
KMAPVLKRIWDQMPDPKWCISMGACSSVGGPFNTYAVLQGVDKIVPVDVYVTGCPPRPENLFYALLKLQDKIDTMTTLVK
RPTEVRLDETMLEEFKQQIRIAQIQNPA

Sequences:

>Translated_188_residues
MSSFIQNQFEQNFITTNVDHVFNWARKSALWPLTFGLACCAIEMIASSTSRFDIARFGAEVFRPSPRQSDLMIVAGTVTL
KMAPVLKRIWDQMPDPKWCISMGACSSVGGPFNTYAVLQGVDKIVPVDVYVTGCPPRPENLFYALLKLQDKIDTMTTLVK
RPTEVRLDETMLEEFKQQIRIAQIQNPA
>Mature_187_residues
SSFIQNQFEQNFITTNVDHVFNWARKSALWPLTFGLACCAIEMIASSTSRFDIARFGAEVFRPSPRQSDLMIVAGTVTLK
MAPVLKRIWDQMPDPKWCISMGACSSVGGPFNTYAVLQGVDKIVPVDVYVTGCPPRPENLFYALLKLQDKIDTMTTLVKR
PTEVRLDETMLEEFKQQIRIAQIQNPA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0377

COG function: function code C; NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 20 kDa subunit family

Homologues:

Organism=Homo sapiens, GI187281616, Length=142, Percent_Identity=54.9295774647887, Blast_Score=184, Evalue=4e-47,
Organism=Escherichia coli, GI1788624, Length=148, Percent_Identity=54.0540540540541, Blast_Score=189, Evalue=7e-50,
Organism=Escherichia coli, GI1789074, Length=151, Percent_Identity=41.7218543046358, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1788834, Length=125, Percent_Identity=41.6, Blast_Score=91, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17509685, Length=165, Percent_Identity=50.3030303030303, Blast_Score=178, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24651058, Length=159, Percent_Identity=52.8301886792453, Blast_Score=184, Evalue=3e-47,
Organism=Drosophila melanogaster, GI18859983, Length=144, Percent_Identity=54.1666666666667, Blast_Score=184, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24642371, Length=144, Percent_Identity=54.1666666666667, Blast_Score=184, Evalue=3e-47,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NUOB1_SOLUE (Q020B6)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_825034.1
- ProteinModelPortal:   Q020B6
- SMR:   Q020B6
- STRING:   Q020B6
- GeneID:   4427971
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_3779
- NMPDR:   fig|234267.9.peg.3587
- eggNOG:   COG0377
- HOGENOM:   HBG553221
- OMA:   SALWPET
- PhylomeDB:   Q020B6
- ProtClustDB:   CLSK774967
- GO:   GO:0006810
- HAMAP:   MF_01356
- InterPro:   IPR006137
- InterPro:   IPR006138
- InterPro:   IPR014406
- PANTHER:   PTHR11995:SF2
- PANTHER:   PTHR11995
- TIGRFAMs:   TIGR01957

Pfam domain/function: PF01058 Oxidored_q6

EC number: =1.6.99.5

Molecular weight: Translated: 21210; Mature: 21079

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS01150 COMPLEX1_20K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFIQNQFEQNFITTNVDHVFNWARKSALWPLTFGLACCAIEMIASSTSRFDIARFGAE
CCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VFRPSPRQSDLMIVAGTVTLKMAPVLKRIWDQMPDPKWCISMGACSSVGGPFNTYAVLQG
HHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCHHEEECCCHHCCCCCHHHHHHHHH
VDKIVPVDVYVTGCPPRPENLFYALLKLQDKIDTMTTLVKRPTEVRLDETMLEEFKQQIR
HHHEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
IAQIQNPA
HHHCCCCC
>Mature Secondary Structure 
SSFIQNQFEQNFITTNVDHVFNWARKSALWPLTFGLACCAIEMIASSTSRFDIARFGAE
CHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VFRPSPRQSDLMIVAGTVTLKMAPVLKRIWDQMPDPKWCISMGACSSVGGPFNTYAVLQG
HHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCHHEEECCCHHCCCCCHHHHHHHHH
VDKIVPVDVYVTGCPPRPENLFYALLKLQDKIDTMTTLVKRPTEVRLDETMLEEFKQQIR
HHHEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
IAQIQNPA
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA