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The map label for this gene is macB [H]

Identifier: 116622877

GI number: 116622877

Start: 4798256

End: 4800679

Strand: Direct

Name: macB [H]

Synonym: Acid_3778

Alternate gene names: 116622877

Gene position: 4798256-4800679 (Clockwise)

Preceding gene: 116622875

Following gene: 116622878

Centisome position: 48.15

GC content: 65.64

Gene sequence:

>2424_bases
ATGCGCAACGAAATCCGCTACGCTTTTCGTACTCTACTGCGCGACCGGGGATTCGCGCTCATGGTGGTGCTATCGCTGGC
CGTTGGGATCGGGGCCAACACCGCGATTTTCTCCCTGATCAACGGAGTGCTGCTGCGGGCCCCGGATTTTCCCAATCCGG
ATCGCCTGGTGACCCTCACACAGTTCGCGCCCAAGCTCGCCAAGGCCTATCCCTCGTTGCCGATGAATATCGCGATTTAC
ACGGAGTGGCGTAAGCAGCTCACCACCCTCGAAAGCATCGGGATCGCACGCGCCAGCGTCTTCAACCTGACCGGCAGCGG
TCAGCCGGAACAGGTCCGCGGCGCTCTTGTTTCCGCAAGCATCTTCCGCGTCTTCGGCGTACAACCGCACCTTGGCCGGG
TATTCACGGACGAGGAAGACGCCGCCGGGCGCGACCACGTGGTCGTGATCGCCGATGCGCTCTGGCGCCGGCGATTCCAA
GCCGACCCCGGAGTGATCGGGCGAAAGATGTTGCTCGATGGCGAGCCCTGCGAAGTGGTGGGCGTGCTGCCTGCTACCTT
TCACTTTCCTCGCGAAGAAAAGGCCGGGACGCGATTTCTCGGGGAAGGGCTCGAAGTCTACCGGCCGCTGGGCTACGACG
CAGGCGATCTCAAAATCCGAATGGGCGATTTCAATTATTGGGCGACGGCACGCCTCAAACCGGGCGTTTCGCCGGCCCGG
GCGCAGGCCGAACTCAACGTGGTGCAGGCCGGCATCAGCAAACAGATTCCCGGCGATTTCGATTTACATGCGACGCTGAT
GCCGTTGATGGAGCGAATGGTGGGAGAAGTGCGGCAGGGCCTTGTGCTCCTGATGGCGGCTGTGGGCGTCGTGCTGCTCG
TGCTGTGCGTGAACCTGGCCAACCTCTCGCTGGCTCGGGCGGCGGGCAGGGCACGCGAGGCCGCCATTCGCACGGCTCTC
GGGGCGAGCCGCGGGCGCCTGGTCCGGCAATCCCTGGTGGAGAGCACGCTGCTCGCGCTGATCGGCGGAGTGCTCGGTGT
GACGCTGGCGTATTTCGGAGTGCACGCGCTCTTGGCGGCGGCCCCGCTGGATCTGCCGCGGCTCGACGAGGTATCGTTGG
ATCTGCCGGTGCTGCTCTTCGCCCTCGCCATCTCGCTGGGGACGGGGCTATTGTTCGGCGCGCTGCCGGCCTTACGGAGC
GCGCGCTCGGCGCCGTTTGAAACGCTGAAATCCGGCAGCCGCAGCAATACGGAAGGGCGCGGCGGCTTGCGCGTGCGCAA
CCTGCTGGTCAGCCTGGAGGTGGGCCTGAGCGCCGCGCTGCTGGTCACGGCCGGCCTCTTGATCGCAAGCTTCGTCCGCG
TGATGTCGGTGGACAAGGGCTTCAACGTGGAGCGCGTACTGGCGGTGAACGTCTCGCTGCTCTCCACGAAATATCCCAAG
CCGGCTGCGCGAGCCGAGTTCTTCGACCGCTTGCTGGAGAAGGCGCGGGCGATGCCGGGTGTGCAGGATGCCGCGCTGGT
CTCCGCTCTGCCGATGACGGGAGAGACGTGGATCGATATCGTGGGCATGGAACACGATCCGCGGCCTATGGTGGAGTTGC
CGCCGGCCAATGTGCGCTTCATCAGTCCCGGCTACTTTCAAGCGCTGCGCGTGGGATTGCGCGATGGCCGCGACTTCGCG
GAGCGCGACCGCACTAGCAAAGTAGCGATTGTATCGGCGGCCCTCGCGCAGAGGATTTGGGGCAACCAGAACCCGATCGG
GCGCAAATTGCAGGACGTTGGCGCACTCCTTGAGGTGGTGGGGGTGACGCCGGATATCCGCAGCACTGGCCTGGATCAGA
ACCCGGTCAACATGATCTATTTCCCTTATTGGCAGAGGCCGCAACTTGGCTCGGCGATCCTGCTGCGCTCCGCGATGGAC
CCGCGCGCGCTGGCCGGTTCACTGCGCGCGGCCGTGTGGGCGATCGATGGCGAAGTCACGGTGCCGCAGGTGCGCACGCT
GGAAGAAGTGATGTCGCGCTCGGTATCGCAGCGCCGCTTCCAGATGCTGCTGGTGCTGTTGTTCGCTGGTGCAGCGCTCG
CGCTGGCGGCGTTCGGAACTTACGGCGTGCTCTCGTACGCGGTCACGCGGCGGACGGCGGAGATGGGTATCCGGATGGCG
CTTGGCGCGGCGCAGGGCGACGTGCTGCGCATGGTGCTGCGGCAGGGAATGATGCCGGTGATGGCGGGCCTGGTGGCGGG
AGGCTTGGCGGCAATCGCGGTGGGGGCGTATGTGGAGAGCCTGCTCTTCCAGGTGAGTCCGCGGGATCCGCTGGCCTTCG
GCGTTTCGGCCGCGGTACTCCTGACAGTGTCGGTGGCGGCCTGCCTGATTCCGGCGCGCCGCGCCACCCGGGTCAACCCG
ATCGACGCATTGCGGTTCGAATAG

Upstream 100 bases:

>100_bases
CACTGGAATGGAACCATTGCTACTGTTTCGTCATCATTTGTAAACCCAATTGTCATAAATGAGGCGAACCGAATCCTGCG
CCGGGACGTACTAGTCTTCG

Downstream 100 bases:

>100_bases
CATTTTCAATGTGCCGTGATAGAATGCGGGTTAACCAACAAGGAGAGCTGGATGTCGTCCTTTATTCAGAACCAGTTCGA
ACAGAATTTCATCACCACCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 807; Mature: 807

Protein sequence:

>807_residues
MRNEIRYAFRTLLRDRGFALMVVLSLAVGIGANTAIFSLINGVLLRAPDFPNPDRLVTLTQFAPKLAKAYPSLPMNIAIY
TEWRKQLTTLESIGIARASVFNLTGSGQPEQVRGALVSASIFRVFGVQPHLGRVFTDEEDAAGRDHVVVIADALWRRRFQ
ADPGVIGRKMLLDGEPCEVVGVLPATFHFPREEKAGTRFLGEGLEVYRPLGYDAGDLKIRMGDFNYWATARLKPGVSPAR
AQAELNVVQAGISKQIPGDFDLHATLMPLMERMVGEVRQGLVLLMAAVGVVLLVLCVNLANLSLARAAGRAREAAIRTAL
GASRGRLVRQSLVESTLLALIGGVLGVTLAYFGVHALLAAAPLDLPRLDEVSLDLPVLLFALAISLGTGLLFGALPALRS
ARSAPFETLKSGSRSNTEGRGGLRVRNLLVSLEVGLSAALLVTAGLLIASFVRVMSVDKGFNVERVLAVNVSLLSTKYPK
PAARAEFFDRLLEKARAMPGVQDAALVSALPMTGETWIDIVGMEHDPRPMVELPPANVRFISPGYFQALRVGLRDGRDFA
ERDRTSKVAIVSAALAQRIWGNQNPIGRKLQDVGALLEVVGVTPDIRSTGLDQNPVNMIYFPYWQRPQLGSAILLRSAMD
PRALAGSLRAAVWAIDGEVTVPQVRTLEEVMSRSVSQRRFQMLLVLLFAGAALALAAFGTYGVLSYAVTRRTAEMGIRMA
LGAAQGDVLRMVLRQGMMPVMAGLVAGGLAAIAVGAYVESLLFQVSPRDPLAFGVSAAVLLTVSVAACLIPARRATRVNP
IDALRFE

Sequences:

>Translated_807_residues
MRNEIRYAFRTLLRDRGFALMVVLSLAVGIGANTAIFSLINGVLLRAPDFPNPDRLVTLTQFAPKLAKAYPSLPMNIAIY
TEWRKQLTTLESIGIARASVFNLTGSGQPEQVRGALVSASIFRVFGVQPHLGRVFTDEEDAAGRDHVVVIADALWRRRFQ
ADPGVIGRKMLLDGEPCEVVGVLPATFHFPREEKAGTRFLGEGLEVYRPLGYDAGDLKIRMGDFNYWATARLKPGVSPAR
AQAELNVVQAGISKQIPGDFDLHATLMPLMERMVGEVRQGLVLLMAAVGVVLLVLCVNLANLSLARAAGRAREAAIRTAL
GASRGRLVRQSLVESTLLALIGGVLGVTLAYFGVHALLAAAPLDLPRLDEVSLDLPVLLFALAISLGTGLLFGALPALRS
ARSAPFETLKSGSRSNTEGRGGLRVRNLLVSLEVGLSAALLVTAGLLIASFVRVMSVDKGFNVERVLAVNVSLLSTKYPK
PAARAEFFDRLLEKARAMPGVQDAALVSALPMTGETWIDIVGMEHDPRPMVELPPANVRFISPGYFQALRVGLRDGRDFA
ERDRTSKVAIVSAALAQRIWGNQNPIGRKLQDVGALLEVVGVTPDIRSTGLDQNPVNMIYFPYWQRPQLGSAILLRSAMD
PRALAGSLRAAVWAIDGEVTVPQVRTLEEVMSRSVSQRRFQMLLVLLFAGAALALAAFGTYGVLSYAVTRRTAEMGIRMA
LGAAQGDVLRMVLRQGMMPVMAGLVAGGLAAIAVGAYVESLLFQVSPRDPLAFGVSAAVLLTVSVAACLIPARRATRVNP
IDALRFE
>Mature_807_residues
MRNEIRYAFRTLLRDRGFALMVVLSLAVGIGANTAIFSLINGVLLRAPDFPNPDRLVTLTQFAPKLAKAYPSLPMNIAIY
TEWRKQLTTLESIGIARASVFNLTGSGQPEQVRGALVSASIFRVFGVQPHLGRVFTDEEDAAGRDHVVVIADALWRRRFQ
ADPGVIGRKMLLDGEPCEVVGVLPATFHFPREEKAGTRFLGEGLEVYRPLGYDAGDLKIRMGDFNYWATARLKPGVSPAR
AQAELNVVQAGISKQIPGDFDLHATLMPLMERMVGEVRQGLVLLMAAVGVVLLVLCVNLANLSLARAAGRAREAAIRTAL
GASRGRLVRQSLVESTLLALIGGVLGVTLAYFGVHALLAAAPLDLPRLDEVSLDLPVLLFALAISLGTGLLFGALPALRS
ARSAPFETLKSGSRSNTEGRGGLRVRNLLVSLEVGLSAALLVTAGLLIASFVRVMSVDKGFNVERVLAVNVSLLSTKYPK
PAARAEFFDRLLEKARAMPGVQDAALVSALPMTGETWIDIVGMEHDPRPMVELPPANVRFISPGYFQALRVGLRDGRDFA
ERDRTSKVAIVSAALAQRIWGNQNPIGRKLQDVGALLEVVGVTPDIRSTGLDQNPVNMIYFPYWQRPQLGSAILLRSAMD
PRALAGSLRAAVWAIDGEVTVPQVRTLEEVMSRSVSQRRFQMLLVLLFAGAALALAAFGTYGVLSYAVTRRTAEMGIRMA
LGAAQGDVLRMVLRQGMMPVMAGLVAGGLAAIAVGAYVESLLFQVSPRDPLAFGVSAAVLLTVSVAACLIPARRATRVNP
IDALRFE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=297, Percent_Identity=30.976430976431, Blast_Score=90, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 86853; Mature: 86853

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNEIRYAFRTLLRDRGFALMVVLSLAVGIGANTAIFSLINGVLLRAPDFPNPDRLVTLT
CCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCCCCCCEEEHH
QFAPKLAKAYPSLPMNIAIYTEWRKQLTTLESIGIARASVFNLTGSGQPEQVRGALVSAS
HHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCHHHHHEEECCCCCCHHHHHHHHHHHH
IFRVFGVQPHLGRVFTDEEDAAGRDHVVVIADALWRRRFQADPGVIGRKMLLDGEPCEVV
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCEEECCCCCEEE
GVLPATFHFPREEKAGTRFLGEGLEVYRPLGYDAGDLKIRMGDFNYWATARLKPGVSPAR
EECCHHCCCCCCCCCCHHHHHCCHHHHHCCCCCCCCEEEEECCCCEEEEEEECCCCCHHH
AQAELNVVQAGISKQIPGDFDLHATLMPLMERMVGEVRQGLVLLMAAVGVVLLVLCVNLA
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLSLARAAGRAREAAIRTALGASRGRLVRQSLVESTLLALIGGVLGVTLAYFGVHALLAA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APLDLPRLDEVSLDLPVLLFALAISLGTGLLFGALPALRSARSAPFETLKSGSRSNTEGR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCC
GGLRVRNLLVSLEVGLSAALLVTAGLLIASFVRVMSVDKGFNVERVLAVNVSLLSTKYPK
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHCCCCC
PAARAEFFDRLLEKARAMPGVQDAALVSALPMTGETWIDIVGMEHDPRPMVELPPANVRF
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCCEECCCCCEEE
ISPGYFQALRVGLRDGRDFAERDRTSKVAIVSAALAQRIWGNQNPIGRKLQDVGALLEVV
ECCHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
GVTPDIRSTGLDQNPVNMIYFPYWQRPQLGSAILLRSAMDPRALAGSLRAAVWAIDGEVT
CCCCCHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHEEEEECCCEE
VPQVRTLEEVMSRSVSQRRFQMLLVLLFAGAALALAAFGTYGVLSYAVTRRTAEMGIRMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGAAQGDVLRMVLRQGMMPVMAGLVAGGLAAIAVGAYVESLLFQVSPRDPLAFGVSAAVL
HCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LTVSVAACLIPARRATRVNPIDALRFE
HHHHHHHHHHHHHHCCCCCCCHHCCCC
>Mature Secondary Structure
MRNEIRYAFRTLLRDRGFALMVVLSLAVGIGANTAIFSLINGVLLRAPDFPNPDRLVTLT
CCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCCCCCCEEEHH
QFAPKLAKAYPSLPMNIAIYTEWRKQLTTLESIGIARASVFNLTGSGQPEQVRGALVSAS
HHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCHHHHHEEECCCCCCHHHHHHHHHHHH
IFRVFGVQPHLGRVFTDEEDAAGRDHVVVIADALWRRRFQADPGVIGRKMLLDGEPCEVV
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCEEECCCCCEEE
GVLPATFHFPREEKAGTRFLGEGLEVYRPLGYDAGDLKIRMGDFNYWATARLKPGVSPAR
EECCHHCCCCCCCCCCHHHHHCCHHHHHCCCCCCCCEEEEECCCCEEEEEEECCCCCHHH
AQAELNVVQAGISKQIPGDFDLHATLMPLMERMVGEVRQGLVLLMAAVGVVLLVLCVNLA
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLSLARAAGRAREAAIRTALGASRGRLVRQSLVESTLLALIGGVLGVTLAYFGVHALLAA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APLDLPRLDEVSLDLPVLLFALAISLGTGLLFGALPALRSARSAPFETLKSGSRSNTEGR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCC
GGLRVRNLLVSLEVGLSAALLVTAGLLIASFVRVMSVDKGFNVERVLAVNVSLLSTKYPK
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHCCCCC
PAARAEFFDRLLEKARAMPGVQDAALVSALPMTGETWIDIVGMEHDPRPMVELPPANVRF
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCCEECCCCCEEE
ISPGYFQALRVGLRDGRDFAERDRTSKVAIVSAALAQRIWGNQNPIGRKLQDVGALLEVV
ECCHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
GVTPDIRSTGLDQNPVNMIYFPYWQRPQLGSAILLRSAMDPRALAGSLRAAVWAIDGEVT
CCCCCHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHEEEEECCCEE
VPQVRTLEEVMSRSVSQRRFQMLLVLLFAGAALALAAFGTYGVLSYAVTRRTAEMGIRMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGAAQGDVLRMVLRQGMMPVMAGLVAGGLAAIAVGAYVESLLFQVSPRDPLAFGVSAAVL
HCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LTVSVAACLIPARRATRVNPIDALRFE
HHHHHHHHHHHHHHCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA