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The map label for this gene is yabD [H]

Identifier: 116622454

GI number: 116622454

Start: 4240476

End: 4241249

Strand: Reverse

Name: yabD [H]

Synonym: Acid_3352

Alternate gene names: 116622454

Gene position: 4241249-4240476 (Counterclockwise)

Preceding gene: 116622455

Following gene: 116622453

Centisome position: 42.56

GC content: 64.86

Gene sequence:

>774_bases
GTGACGCTGGTCGATTCCCATTGTCATCTCGATGACGAAAAGTTCGATGCCGACCGCGAGCAGGTGATGGAGCGCGCCCT
CGCGGCCGGTGTGGAGACGATGATGGCCATTGGGACCGGCGGCGAGTTGGATGTCGCCATCCGGCAGGCCGAGCGGTATC
CGTTTATCTACGCCACCATCGGCGTGCACCCGCACGATGCGTCCAAGGCCACGGAGGAGACGTACGCCCGGCTGCGCGAT
CTTTCCGCGCATCCCAAGGTGCTGGCGATCGGTGAGATCGGCCTCGACTATCACTACGATTTCTCGCCGCGCGACGTGCA
GCGCGAGGTCTTCGACCGGCAATTGGAAATCGCGGCGCTTGCCGCCAAGCCGATCGTGATTCACACCCGGGAAGCCTGGG
AGGACACAGTGGCGCAGGTCGCTTCCCTGCCCCACGGCGGGATCATGCACTGCTTCACCGGCGACGAAGCGCAGGCCCGG
GAGGCGCTGGCGCTCGGTTTTCACCTGAGTTTCGGGGGTGTGCTGACGTTTCCCAAGGCCGAATCCGTGCGCCAGGCGGC
GCGGATCACGCCGGACGACCGCCTCCTCGTGGAGACCGATTGCCCCTACCTGGCGCCGGTCCCCCATCGTGGAAAACGCA
ATGAACCCGCATTCGTGGTGGAGACCGCGAGGCGGCTCGCAGCCGTTCGCGGCACCACAATCGATGCGATTGCCGGGATC
ACCAGCCGCAATTTTCGGAGCCTGTGTTTGCACGCGCCGATGGCGAACAGTTAA

Upstream 100 bases:

>100_bases
GCATCGAGTCCAATGGGATGATCGTCGCGGCATCGGTGGAAGGCGGCAAGCCCGTGCTTACCGGATTCCATGAAGAAATC
CCGGTGGGAGCGCGCCTGAA

Downstream 100 bases:

>100_bases
ACTGGTTAACTTACATGAATTTAGGCAAGCTGGGGCAGGCTCTCACAGCTCGGGAAATCTTCGACCTCATCCAGGACGAT
TTGGAGCAGGTCGAAAAGAA

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTLVDSHCHLDDEKFDADREQVMERALAAGVETMMAIGTGGELDVAIRQAERYPFIYATIGVHPHDASKATEETYARLRD
LSAHPKVLAIGEIGLDYHYDFSPRDVQREVFDRQLEIAALAAKPIVIHTREAWEDTVAQVASLPHGGIMHCFTGDEAQAR
EALALGFHLSFGGVLTFPKAESVRQAARITPDDRLLVETDCPYLAPVPHRGKRNEPAFVVETARRLAAVRGTTIDAIAGI
TSRNFRSLCLHAPMANS

Sequences:

>Translated_257_residues
MTLVDSHCHLDDEKFDADREQVMERALAAGVETMMAIGTGGELDVAIRQAERYPFIYATIGVHPHDASKATEETYARLRD
LSAHPKVLAIGEIGLDYHYDFSPRDVQREVFDRQLEIAALAAKPIVIHTREAWEDTVAQVASLPHGGIMHCFTGDEAQAR
EALALGFHLSFGGVLTFPKAESVRQAARITPDDRLLVETDCPYLAPVPHRGKRNEPAFVVETARRLAAVRGTTIDAIAGI
TSRNFRSLCLHAPMANS
>Mature_256_residues
TLVDSHCHLDDEKFDADREQVMERALAAGVETMMAIGTGGELDVAIRQAERYPFIYATIGVHPHDASKATEETYARLRDL
SAHPKVLAIGEIGLDYHYDFSPRDVQREVFDRQLEIAALAAKPIVIHTREAWEDTVAQVASLPHGGIMHCFTGDEAQARE
ALALGFHLSFGGVLTFPKAESVRQAARITPDDRLLVETDCPYLAPVPHRGKRNEPAFVVETARRLAAVRGTTIDAIAGIT
SRNFRSLCLHAPMANS

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=204, Percent_Identity=36.2745098039216, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI110349730, Length=259, Percent_Identity=29.3436293436293, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI226061853, Length=267, Percent_Identity=29.9625468164794, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI110349734, Length=260, Percent_Identity=30, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI14042943, Length=253, Percent_Identity=26.8774703557312, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI226061614, Length=251, Percent_Identity=26.6932270916335, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=30.5676855895196, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI225903439, Length=227, Percent_Identity=26.431718061674, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=41.796875, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI48994985, Length=256, Percent_Identity=33.984375, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI87082439, Length=251, Percent_Identity=31.0756972111554, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=278, Percent_Identity=34.1726618705036, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71980746, Length=260, Percent_Identity=27.6923076923077, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17565396, Length=229, Percent_Identity=28.82096069869, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648690, Length=278, Percent_Identity=32.0143884892086, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24586117, Length=222, Percent_Identity=31.5315315315315, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI221330018, Length=222, Percent_Identity=31.5315315315315, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28281; Mature: 28150

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3 ; PS00669 GAS_VESICLE_A_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVDSHCHLDDEKFDADREQVMERALAAGVETMMAIGTGGELDVAIRQAERYPFIYATI
CCEECCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHEEEHHCCCCEEEEEE
GVHPHDASKATEETYARLRDLSAHPKVLAIGEIGLDYHYDFSPRDVQREVFDRQLEIAAL
CCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCEECCCCHHHHHHHHHHHHHHHHEE
AAKPIVIHTREAWEDTVAQVASLPHGGIMHCFTGDEAQAREALALGFHLSFGGVLTFPKA
ECCCEEEECHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHEEEEEECCCEEECCCH
ESVRQAARITPDDRLLVETDCPYLAPVPHRGKRNEPAFVVETARRLAAVRGTTIDAIAGI
HHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCC
TSRNFRSLCLHAPMANS
CCCCHHHHEEECCCCCC
>Mature Secondary Structure 
TLVDSHCHLDDEKFDADREQVMERALAAGVETMMAIGTGGELDVAIRQAERYPFIYATI
CEECCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHEEEHHCCCCEEEEEE
GVHPHDASKATEETYARLRDLSAHPKVLAIGEIGLDYHYDFSPRDVQREVFDRQLEIAAL
CCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCEECCCCHHHHHHHHHHHHHHHHEE
AAKPIVIHTREAWEDTVAQVASLPHGGIMHCFTGDEAQAREALALGFHLSFGGVLTFPKA
ECCCEEEECHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHEEEEEECCCEEECCCH
ESVRQAARITPDDRLLVETDCPYLAPVPHRGKRNEPAFVVETARRLAAVRGTTIDAIAGI
HHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCC
TSRNFRSLCLHAPMANS
CCCCHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]