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The map label for this gene is mocR [H]

Identifier: 116621719

GI number: 116621719

Start: 3282971

End: 3284428

Strand: Reverse

Name: mocR [H]

Synonym: Acid_2601

Alternate gene names: 116621719

Gene position: 3284428-3282971 (Counterclockwise)

Preceding gene: 116621722

Following gene: 116621717

Centisome position: 32.96

GC content: 70.16

Gene sequence:

>1458_bases
ATGTTACTGACCCTCGGCGGAGGAGGTCCGCTCTTCCACCAGGTGTTCCGCGCAGCGCGGGAGGCGATTCTGAGCGGACG
GGTTCGCGCGGGCGAGCGGCTGCCGGTGACGCGGGCGCTGGCGCGCGAGCTGGGCGTGTCGCGCAACGTGGTGCTGATCG
CGTACGAGCAGTTGATCGCGGAGGGCTACGCGGAAGGGCGGGTGGGGTCGGGAACGTACGTGGCGGCGACGGTGCCGGAG
GCGATGACGCGAGCGGCGGCGCGATCGAAGGCGGGCGGCGCGGAAGGTCCGGGGGAGACGCGACTCTCGCGGTACGGGTC
GCGGATTCTGGCAGACCCGGAGAGCGATGCCCCGCTGACGACCGCGGGCAGGCGGACGCGCTACGACTTCGCGTACTACT
TGTCGCGGGGGGAGGACTTCCCCGCCCCGTTGTGGCGGCAGCTGCTTTCGCGGCGATTGCGGCGGCTGGAGTTGGATTAC
GCGGCCGTGCAGGGCGATAGCGGACTGCGGCGCGAGATCGCGCGCTACCTGCGGCGGACGCGCGGGATCGAATGCACGGC
GGAGCAGGTGCTGCTGGTGAATGGCTCGCAGCAGGCGATGGACCTGGTGGGCCGGGTGCTGTTGGACGCGGGCGACCGGG
TGGTGATGGAAAATCCGCACTACACCGGGGCGCGCGAGGTGTTCCGGGCGGTGGGCGCGCGGATTGTGCCGGTGGCGGTG
GACGAGCAGGGGATCGACGTGGAGCAGCTGCCGCGATCGGCGCGGCTGGCGTATGTGACGCCCTCGCACCAGTTTCCGAC
TGGTGCGATCCTGCCGCTGGACCGGCGACTGGCGCTGCTATCGTGGGCGGAGCGCAACCAGGCGTACATCCTTGAGGACG
ATTACGACGGCGAGTATCGGTATGAGGGGCGTCCGGTAGAGGCGGTGCAGGCGATGGACCGGACGGGGCGGGTGGTGTAC
ACAGGGAGTTTTTCGCGGGTGCTGTTTCCTTCGCTGCGGATGGGATACCTGGTGGCACCGCGCGCGCTGGCGGGGGCGCT
GGCGAAGGCGAAGTGGATCGCGGACCGGCACACGAGTTTTCTGCAGCAGGCGGCGCTGGCGGATTTGATGCGAGAGGGAC
ATTTGGACCGGCTGGTGCGGCGGGCGCGAGTGCGGAATGCGGCGCGGCGGGAGGCGCTGCTGCGGGCATTAGAGCGGGAT
TTCGGGGACGCGGTAGAGGTGCGCGGAGCGGCGGCGGGAGTGCATGTGCTCGCCTGCTTTCCGAAGCTGACGGCCGGGGA
CACGGCAAGTTTGGTGGAGGCGGCGGCGAAGGCGGGCGTGCGCGTGTATTCGACGGCGCACTATTATTTGGGGGCGGCGC
CGCGGTGCGAACTGCTGTTGGGGTATGGCGCGATGAGCGAGCGCGAGATCGCGGCGGGGGTGAGGATGCTGGCGGTAGCG
CTCGGGCAGCGGCGCTGA

Upstream 100 bases:

>100_bases
GAGTAAAAGGAAGAGACTGGCGAGAACCCTCATGGTTCCAGGCTACGCGGGAATTGGCCTTTGACAAGAGCCAATTCCGA
GCAGGATGATGGAGCCAATT

Downstream 100 bases:

>100_bases
GCTTCGGCTTACACGTGTTACGGGATCGCTCCCTTGCGGTCGCGGCTCTGATGAAAGCGAGGGCGAGTTCGAGCTAGGTT
TTTAGTTCGGCGACGATCTC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MLLTLGGGGPLFHQVFRAAREAILSGRVRAGERLPVTRALARELGVSRNVVLIAYEQLIAEGYAEGRVGSGTYVAATVPE
AMTRAAARSKAGGAEGPGETRLSRYGSRILADPESDAPLTTAGRRTRYDFAYYLSRGEDFPAPLWRQLLSRRLRRLELDY
AAVQGDSGLRREIARYLRRTRGIECTAEQVLLVNGSQQAMDLVGRVLLDAGDRVVMENPHYTGAREVFRAVGARIVPVAV
DEQGIDVEQLPRSARLAYVTPSHQFPTGAILPLDRRLALLSWAERNQAYILEDDYDGEYRYEGRPVEAVQAMDRTGRVVY
TGSFSRVLFPSLRMGYLVAPRALAGALAKAKWIADRHTSFLQQAALADLMREGHLDRLVRRARVRNAARREALLRALERD
FGDAVEVRGAAAGVHVLACFPKLTAGDTASLVEAAAKAGVRVYSTAHYYLGAAPRCELLLGYGAMSEREIAAGVRMLAVA
LGQRR

Sequences:

>Translated_485_residues
MLLTLGGGGPLFHQVFRAAREAILSGRVRAGERLPVTRALARELGVSRNVVLIAYEQLIAEGYAEGRVGSGTYVAATVPE
AMTRAAARSKAGGAEGPGETRLSRYGSRILADPESDAPLTTAGRRTRYDFAYYLSRGEDFPAPLWRQLLSRRLRRLELDY
AAVQGDSGLRREIARYLRRTRGIECTAEQVLLVNGSQQAMDLVGRVLLDAGDRVVMENPHYTGAREVFRAVGARIVPVAV
DEQGIDVEQLPRSARLAYVTPSHQFPTGAILPLDRRLALLSWAERNQAYILEDDYDGEYRYEGRPVEAVQAMDRTGRVVY
TGSFSRVLFPSLRMGYLVAPRALAGALAKAKWIADRHTSFLQQAALADLMREGHLDRLVRRARVRNAARREALLRALERD
FGDAVEVRGAAAGVHVLACFPKLTAGDTASLVEAAAKAGVRVYSTAHYYLGAAPRCELLLGYGAMSEREIAAGVRMLAVA
LGQRR
>Mature_485_residues
MLLTLGGGGPLFHQVFRAAREAILSGRVRAGERLPVTRALARELGVSRNVVLIAYEQLIAEGYAEGRVGSGTYVAATVPE
AMTRAAARSKAGGAEGPGETRLSRYGSRILADPESDAPLTTAGRRTRYDFAYYLSRGEDFPAPLWRQLLSRRLRRLELDY
AAVQGDSGLRREIARYLRRTRGIECTAEQVLLVNGSQQAMDLVGRVLLDAGDRVVMENPHYTGAREVFRAVGARIVPVAV
DEQGIDVEQLPRSARLAYVTPSHQFPTGAILPLDRRLALLSWAERNQAYILEDDYDGEYRYEGRPVEAVQAMDRTGRVVY
TGSFSRVLFPSLRMGYLVAPRALAGALAKAKWIADRHTSFLQQAALADLMREGHLDRLVRRARVRNAARREALLRALERD
FGDAVEVRGAAAGVHVLACFPKLTAGDTASLVEAAAKAGVRVYSTAHYYLGAAPRCELLLGYGAMSEREIAAGVRMLAVA
LGQRR

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=314, Percent_Identity=24.8407643312102, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI33469970, Length=314, Percent_Identity=24.8407643312102, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1790797, Length=394, Percent_Identity=30.2030456852792, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787710, Length=461, Percent_Identity=26.2472885032538, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53163; Mature: 53163

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTLGGGGPLFHQVFRAAREAILSGRVRAGERLPVTRALARELGVSRNVVLIAYEQLIA
CEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHH
EGYAEGRVGSGTYVAATVPEAMTRAAARSKAGGAEGPGETRLSRYGSRILADPESDAPLT
CCCCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEECCCCCCCCCC
TAGRRTRYDFAYYLSRGEDFPAPLWRQLLSRRLRRLELDYAAVQGDSGLRREIARYLRRT
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHH
RGIECTAEQVLLVNGSQQAMDLVGRVLLDAGDRVVMENPHYTGAREVFRAVGARIVPVAV
CCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCEEEEEEE
DEQGIDVEQLPRSARLAYVTPSHQFPTGAILPLDRRLALLSWAERNQAYILEDDYDGEYR
CCCCCCHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEE
YEGRPVEAVQAMDRTGRVVYTGSFSRVLFPSLRMGYLVAPRALAGALAKAKWIADRHTSF
ECCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LQQAALADLMREGHLDRLVRRARVRNAARREALLRALERDFGDAVEVRGAAAGVHVLACF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHCEEHEECC
PKLTAGDTASLVEAAAKAGVRVYSTAHYYLGAAPRCELLLGYGAMSEREIAAGVRMLAVA
CCCCCCCHHHHHHHHHHCCEEEEEEHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LGQRR
HCCCC
>Mature Secondary Structure
MLLTLGGGGPLFHQVFRAAREAILSGRVRAGERLPVTRALARELGVSRNVVLIAYEQLIA
CEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHH
EGYAEGRVGSGTYVAATVPEAMTRAAARSKAGGAEGPGETRLSRYGSRILADPESDAPLT
CCCCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEECCCCCCCCCC
TAGRRTRYDFAYYLSRGEDFPAPLWRQLLSRRLRRLELDYAAVQGDSGLRREIARYLRRT
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHH
RGIECTAEQVLLVNGSQQAMDLVGRVLLDAGDRVVMENPHYTGAREVFRAVGARIVPVAV
CCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCEEEEEEE
DEQGIDVEQLPRSARLAYVTPSHQFPTGAILPLDRRLALLSWAERNQAYILEDDYDGEYR
CCCCCCHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEE
YEGRPVEAVQAMDRTGRVVYTGSFSRVLFPSLRMGYLVAPRALAGALAKAKWIADRHTSF
ECCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LQQAALADLMREGHLDRLVRRARVRNAARREALLRALERDFGDAVEVRGAAAGVHVLACF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHCEEHEECC
PKLTAGDTASLVEAAAKAGVRVYSTAHYYLGAAPRCELLLGYGAMSEREIAAGVRMLAVA
CCCCCCCHHHHHHHHHHCCEEEEEEHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LGQRR
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]