Click here to switch to the map view.

The map label for this gene is 116621717

Identifier: 116621717

GI number: 116621717

Start: 3281428

End: 3281829

Strand: Reverse

Name: 116621717

Synonym: Acid_2599

Alternate gene names: NA

Gene position: 3281829-3281428 (Counterclockwise)

Preceding gene: 116621719

Following gene: 116621704

Centisome position: 32.93

GC content: 62.69

Gene sequence:

>402_bases
GTGGCGGCGCGCAGCAAGGATCCGAATACGCAGATCGGGTGCGTGATCGTGGGTCCGAACCACGAAATCCGCTCGACCGG
GTACAACTCTTTCCCGCGGGGAATCCGCGACGACGTCCCGGAGCGGCTGGTGCGGCCGACGAAATATTTGTGGATCGAGC
ACGCCGAGCGCAATGCGATCTGCAACGCGGCGCGAGCGGGCACGGCCACGGAAGGCTGCACGATTTACGTGGATATCATG
CCTTGCATGGATTGCGCGCGGGCGGTGGTGCAAGCGGGAATCGTGGCGGTGGTGATCTCGGCGGAGCGGATGACACAGTA
TTCGAGCGACTACTACAACGAGCATTTCGGGATGGTGGAAGTGTTGTTCGGCGAGGCCGGCGTGACGGTGCGGAGAGTAT
AG

Upstream 100 bases:

>100_bases
GAAAACCTACCAGCTTGCCTGAAAGGGAGAAGAAATGCAACTGTAGGGTATGCGAACGATCCCTTCCTGGGACCAATACA
ACCTGGAAATCTGTAGAACC

Downstream 100 bases:

>100_bases
AGAGGCATTTAGATCGCTCCCTCACGGTCGCGGTTCGCGGAGCCGTGTCTGCATGCGCGGGACGCCGGCTGAAGCCGGCG
GCAGCCAGGATTGGCTGCCC

Product: zinc-binding CMP/dCMP deaminase

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MAARSKDPNTQIGCVIVGPNHEIRSTGYNSFPRGIRDDVPERLVRPTKYLWIEHAERNAICNAARAGTATEGCTIYVDIM
PCMDCARAVVQAGIVAVVISAERMTQYSSDYYNEHFGMVEVLFGEAGVTVRRV

Sequences:

>Translated_133_residues
MAARSKDPNTQIGCVIVGPNHEIRSTGYNSFPRGIRDDVPERLVRPTKYLWIEHAERNAICNAARAGTATEGCTIYVDIM
PCMDCARAVVQAGIVAVVISAERMTQYSSDYYNEHFGMVEVLFGEAGVTVRRV
>Mature_132_residues
AARSKDPNTQIGCVIVGPNHEIRSTGYNSFPRGIRDDVPERLVRPTKYLWIEHAERNAICNAARAGTATEGCTIYVDIMP
CMDCARAVVQAGIVAVVISAERMTQYSSDYYNEHFGMVEVLFGEAGVTVRRV

Specific function: Unknown

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=136, Percent_Identity=38.9705882352941, Blast_Score=93, Evalue=5e-20,
Organism=Homo sapiens, GI61742821, Length=136, Percent_Identity=38.9705882352941, Blast_Score=93, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17557019, Length=109, Percent_Identity=43.1192660550459, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24667298, Length=112, Percent_Identity=36.6071428571429, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24667302, Length=112, Percent_Identity=36.6071428571429, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 14698; Mature: 14567

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARSKDPNTQIGCVIVGPNHEIRSTGYNSFPRGIRDDVPERLVRPTKYLWIEHAERNAI
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHH
CNAARAGTATEGCTIYVDIMPCMDCARAVVQAGIVAVVISAERMTQYSSDYYNEHFGMVE
HHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHCHHHEEEEHHHHHHHHHHHHHHCCCCEE
VLFGEAGVTVRRV
EEECCCCEEEECC
>Mature Secondary Structure 
AARSKDPNTQIGCVIVGPNHEIRSTGYNSFPRGIRDDVPERLVRPTKYLWIEHAERNAI
CCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHH
CNAARAGTATEGCTIYVDIMPCMDCARAVVQAGIVAVVISAERMTQYSSDYYNEHFGMVE
HHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHCHHHEEEEHHHHHHHHHHHHHHCCCCEE
VLFGEAGVTVRRV
EEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8329441 [H]