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The map label for this gene is yagR [H]

Identifier: 116621538

GI number: 116621538

Start: 3082196

End: 3084343

Strand: Direct

Name: yagR [H]

Synonym: Acid_2420

Alternate gene names: 116621538

Gene position: 3082196-3084343 (Clockwise)

Preceding gene: 116621537

Following gene: 116621539

Centisome position: 30.93

GC content: 63.83

Gene sequence:

>2148_bases
ATGGCTAACACACCGGACTATAGCTGGCCGCCGATGGCGGATCGCAAAATCATGGGCAAGCCCTTCAAGCGCCTGGACGG
CCCACTGAAGGCCGCGGGCCGCGCCAAGTACACGTCCGACCTGAAGATGAAGGACATGCTGTTCGCGGCCTACGTACTGT
GTCCGCACGGGCATGCCCGCGTCACTGCGATCGATACCAGCGCGGCGGAGAAGATGAAGGGCGTGATGTCGGTCCACGTA
ATCGCGCCGGCCGGCACGGAAGTGCAGTGGCACGGCAAGGAGATCGCGGCGCTCGCGGCGACTACGGAAGAGATCGCGCG
CGAGGCCATCCGCAAGGTCAAAGTGGATTACGAAGTGCTGCCCCACTTCGTGAATGAGGCCGACCTGGGCAAGGCCGGTT
CGCGCGGCAAGGCCGCCGGAGAAAAGGTTACCGGCGATCCGGAGAAGGCGTTCCAGGATGCGGAAGCCGTTTCCGACGGC
GTGTACGGCATTCCGGTGGTCACGCACTCCTGCCTGGAACCTCACGGCTGCGTCATCCAGTGGCAGGGCGACCAGGTGAT
GGCGTGGCCCTCCACGCAGTTCGTCACCGGCTGGGCAAACACGCTGGCGCCGAACCTAAAAGTCCCGGCCGCGAACATCA
AGGTGAAGATGGATTACATCGGAGGCGGCTTCGGCAGCAAGTTCAGCCCGGGAGCCTGGGCCGAGATCGGCGCGATTCTC
TCGCAGAAGGCGGGCGGCAAGCCGGTCAAGATTTACCTGGATCGCGTGGCCGAGCAGACGATCGCGGGCAATCGCCCGAG
CGCGTTCGGCAAGATCAAAGTCGCGGGGAAGAAAGACGGAACCATCACCGCGTGGCAGAGCGACACGTGGGCGAGCGGCG
GCTTCGCGGGCGGCGGACAGCCTCCGCTGCCGTATGTCTATACCAACATTCCCAACACGCGTCTGAATCACACCTCGATC
TCCGTCAACGCGGGACCGAGCCAGGCATGGCGCGCGCCCAACAACCAGCAGGCGAGTTATCTGACCTGCTCGGCAATCGA
GGATTTCGCCGCCAAGGCCGGCTGCGACCCGATGGATGTGTTCCACAAAAATGCGGGCTACACGCCGCGCGCGGAGCAGT
ATCAGTATCAGCTCGGCAAAGCCGCGGAACTCTCCGAATGGAAGAAGTTGTGGAAGCCGCGCGGCCAGCAAACCGGCGCG
GTACGCCGCGGTCTCGGTATCGGCGTCAACGCGTGGGCCGGCAACGGTCACGGATGCACGTCGCGGGTGACGATCAATTC
GGATGGCTCGGTGCTGGTCGAAATGGGCACGCAGGATCTGGGCACCGGGACGCGCACCATCATGACGCAGGTGGCGGCCG
AGACGCTCGGGCTGTCGATGGGCCAGGTCAAACTGGTGATCGGCGATAACAGCCTGCCGCCGGGCGGAAGCTCCGGCGGG
TCTACCACGGTGGGCGGTGTTTCGTCGGCGACCCGGAAGGCCGGCATCAACGCGCTGGCCAAGCTGTACGAAGTCGCGGC
TCCGGCGTTGGGCGTTCAGCCTGACGATCTGGAAGCCGTGGATGGCAACATCCGGTCGAAATCGAATCACGCCAAGACCA
TGACCTGGGCGGCCGCGTGCAAGAAGATTCCGGCCGCGCAGGGAAAGATCGTCGAGACCGGCGCCAACGACACGCGCAAC
CCGATGGGGCTGTTCAGCGGCGGCGCGGCCGGCGTGCAGGTTGCCGACGTGAGCGTGGATACCGAGACCGGGCTGGTCAA
GATCAACCGCTTCGTGGCGGTGCAGGATTGCGGACTGATCATTAATCCGCGTCTCGCCGAAAGCCAGATCTTCGGAGCCA
TCATCATGGGCATCTCGACGGCGCTGTTTGAAGAACGCATCATGGACAACAACACGGGCCGCATGATGAATCCCGACCTG
GAGTTTTACAAGCTGGCGGGCATCAAAGACATCGGCGATATCGTGGTGCACCTGGATATCCGCGAAGTGAATGACAAGCG
CGGCGTCATCGGGCTCGGAGAACCGCCGGCGATCGGCATCTGCGCCGCCGTGGGCAACGCGGTGGCGAATGCGGTCGGCA
TGCGCGTACCGAATATGCCGATGTCTCCGATGAATGTGCTTAACACGCTGGAAGGGAGGAACGCGTAA

Upstream 100 bases:

>100_bases
GTAAAGCACGGGCTGGGCGGCAATCTCTGCCGCTGCGGCACGTATATGGGCATACGCCAGGCTGTGGTGGAAGCCGCGAA
AAATATGAAGGGGGCGAAGA

Downstream 100 bases:

>100_bases
TGCAGTCGTTCGAATACGCCAATCCGGCGACCGTTCAGGAAGCGGTGGCGCTGCTCTCCGCCAAGTGGGGAGAGGCCGAT
GTACTGGCCGGCGGCACCGA

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 715; Mature: 714

Protein sequence:

>715_residues
MANTPDYSWPPMADRKIMGKPFKRLDGPLKAAGRAKYTSDLKMKDMLFAAYVLCPHGHARVTAIDTSAAEKMKGVMSVHV
IAPAGTEVQWHGKEIAALAATTEEIAREAIRKVKVDYEVLPHFVNEADLGKAGSRGKAAGEKVTGDPEKAFQDAEAVSDG
VYGIPVVTHSCLEPHGCVIQWQGDQVMAWPSTQFVTGWANTLAPNLKVPAANIKVKMDYIGGGFGSKFSPGAWAEIGAIL
SQKAGGKPVKIYLDRVAEQTIAGNRPSAFGKIKVAGKKDGTITAWQSDTWASGGFAGGGQPPLPYVYTNIPNTRLNHTSI
SVNAGPSQAWRAPNNQQASYLTCSAIEDFAAKAGCDPMDVFHKNAGYTPRAEQYQYQLGKAAELSEWKKLWKPRGQQTGA
VRRGLGIGVNAWAGNGHGCTSRVTINSDGSVLVEMGTQDLGTGTRTIMTQVAAETLGLSMGQVKLVIGDNSLPPGGSSGG
STTVGGVSSATRKAGINALAKLYEVAAPALGVQPDDLEAVDGNIRSKSNHAKTMTWAAACKKIPAAQGKIVETGANDTRN
PMGLFSGGAAGVQVADVSVDTETGLVKINRFVAVQDCGLIINPRLAESQIFGAIIMGISTALFEERIMDNNTGRMMNPDL
EFYKLAGIKDIGDIVVHLDIREVNDKRGVIGLGEPPAIGICAAVGNAVANAVGMRVPNMPMSPMNVLNTLEGRNA

Sequences:

>Translated_715_residues
MANTPDYSWPPMADRKIMGKPFKRLDGPLKAAGRAKYTSDLKMKDMLFAAYVLCPHGHARVTAIDTSAAEKMKGVMSVHV
IAPAGTEVQWHGKEIAALAATTEEIAREAIRKVKVDYEVLPHFVNEADLGKAGSRGKAAGEKVTGDPEKAFQDAEAVSDG
VYGIPVVTHSCLEPHGCVIQWQGDQVMAWPSTQFVTGWANTLAPNLKVPAANIKVKMDYIGGGFGSKFSPGAWAEIGAIL
SQKAGGKPVKIYLDRVAEQTIAGNRPSAFGKIKVAGKKDGTITAWQSDTWASGGFAGGGQPPLPYVYTNIPNTRLNHTSI
SVNAGPSQAWRAPNNQQASYLTCSAIEDFAAKAGCDPMDVFHKNAGYTPRAEQYQYQLGKAAELSEWKKLWKPRGQQTGA
VRRGLGIGVNAWAGNGHGCTSRVTINSDGSVLVEMGTQDLGTGTRTIMTQVAAETLGLSMGQVKLVIGDNSLPPGGSSGG
STTVGGVSSATRKAGINALAKLYEVAAPALGVQPDDLEAVDGNIRSKSNHAKTMTWAAACKKIPAAQGKIVETGANDTRN
PMGLFSGGAAGVQVADVSVDTETGLVKINRFVAVQDCGLIINPRLAESQIFGAIIMGISTALFEERIMDNNTGRMMNPDL
EFYKLAGIKDIGDIVVHLDIREVNDKRGVIGLGEPPAIGICAAVGNAVANAVGMRVPNMPMSPMNVLNTLEGRNA
>Mature_714_residues
ANTPDYSWPPMADRKIMGKPFKRLDGPLKAAGRAKYTSDLKMKDMLFAAYVLCPHGHARVTAIDTSAAEKMKGVMSVHVI
APAGTEVQWHGKEIAALAATTEEIAREAIRKVKVDYEVLPHFVNEADLGKAGSRGKAAGEKVTGDPEKAFQDAEAVSDGV
YGIPVVTHSCLEPHGCVIQWQGDQVMAWPSTQFVTGWANTLAPNLKVPAANIKVKMDYIGGGFGSKFSPGAWAEIGAILS
QKAGGKPVKIYLDRVAEQTIAGNRPSAFGKIKVAGKKDGTITAWQSDTWASGGFAGGGQPPLPYVYTNIPNTRLNHTSIS
VNAGPSQAWRAPNNQQASYLTCSAIEDFAAKAGCDPMDVFHKNAGYTPRAEQYQYQLGKAAELSEWKKLWKPRGQQTGAV
RRGLGIGVNAWAGNGHGCTSRVTINSDGSVLVEMGTQDLGTGTRTIMTQVAAETLGLSMGQVKLVIGDNSLPPGGSSGGS
TTVGGVSSATRKAGINALAKLYEVAAPALGVQPDDLEAVDGNIRSKSNHAKTMTWAAACKKIPAAQGKIVETGANDTRNP
MGLFSGGAAGVQVADVSVDTETGLVKINRFVAVQDCGLIINPRLAESQIFGAIIMGISTALFEERIMDNNTGRMMNPDLE
FYKLAGIKDIGDIVVHLDIREVNDKRGVIGLGEPPAIGICAAVGNAVANAVGMRVPNMPMSPMNVLNTLEGRNA

Specific function: Unknown

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=670, Percent_Identity=26.1194029850746, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI91823271, Length=737, Percent_Identity=24.6947082767978, Blast_Score=139, Evalue=9e-33,
Organism=Escherichia coli, GI1786478, Length=739, Percent_Identity=30.446549391069, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI1789230, Length=755, Percent_Identity=27.2847682119205, Blast_Score=220, Evalue=3e-58,
Organism=Escherichia coli, GI1789246, Length=808, Percent_Identity=24.8762376237624, Blast_Score=170, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17540638, Length=681, Percent_Identity=24.5227606461087, Blast_Score=133, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI32566215, Length=714, Percent_Identity=23.8095238095238, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17539860, Length=739, Percent_Identity=22.0568335588633, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI17737937, Length=740, Percent_Identity=27.1621621621622, Blast_Score=144, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24647193, Length=748, Percent_Identity=25, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24647199, Length=714, Percent_Identity=23.249299719888, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24647201, Length=717, Percent_Identity=22.1757322175732, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24647195, Length=719, Percent_Identity=22.3922114047288, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24647197, Length=712, Percent_Identity=22.4719101123595, Blast_Score=103, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 75420; Mature: 75289

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTPDYSWPPMADRKIMGKPFKRLDGPLKAAGRAKYTSDLKMKDMLFAAYVLCPHGHAR
CCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEE
VTAIDTSAAEKMKGVMSVHVIAPAGTEVQWHGKEIAALAATTEEIAREAIRKVKVDYEVL
EEEECCHHHHHHCCEEEEEEECCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHCCCHHHH
PHFVNEADLGKAGSRGKAAGEKVTGDPEKAFQDAEAVSDGVYGIPVVTHSCLEPHGCVIQ
HHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEECHHHHHHHCCCCCCEEE
WQGDQVMAWPSTQFVTGWANTLAPNLKVPAANIKVKMDYIGGGFGSKFSPGAWAEIGAIL
ECCCEEEECCCCCEEECHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHH
SQKAGGKPVKIYLDRVAEQTIAGNRPSAFGKIKVAGKKDGTITAWQSDTWASGGFAGGGQ
HHCCCCCCEEEHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCC
PPLPYVYTNIPNTRLNHTSISVNAGPSQAWRAPNNQQASYLTCSAIEDFAAKAGCDPMDV
CCCCEEEECCCCCEECCEEEEEECCCHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCHHHH
FHKNAGYTPRAEQYQYQLGKAAELSEWKKLWKPRGQQTGAVRRGLGIGVNAWAGNGHGCT
HHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCCEEEECCCCCCCE
SRVTINSDGSVLVEMGTQDLGTGTRTIMTQVAAETLGLSMGQVKLVIGDNSLPPGGSSGG
EEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
STTVGGVSSATRKAGINALAKLYEVAAPALGVQPDDLEAVDGNIRSKSNHAKTMTWAAAC
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHH
KKIPAAQGKIVETGANDTRNPMGLFSGGAAGVQVADVSVDTETGLVKINRFVAVQDCGLI
HHCCCCCCEEEECCCCCCCCCCCEECCCCCCEEEEEEEECCCCCEEEEEEEEEEECCCEE
INPRLAESQIFGAIIMGISTALFEERIMDNNTGRMMNPDLEFYKLAGIKDIGDIVVHLDI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEECCCCCCCCEEEEEEE
REVNDKRGVIGLGEPPAIGICAAVGNAVANAVGMRVPNMPMSPMNVLNTLEGRNA
EECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
ANTPDYSWPPMADRKIMGKPFKRLDGPLKAAGRAKYTSDLKMKDMLFAAYVLCPHGHAR
CCCCCCCCCCCCCCCCCCCCHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEE
VTAIDTSAAEKMKGVMSVHVIAPAGTEVQWHGKEIAALAATTEEIAREAIRKVKVDYEVL
EEEECCHHHHHHCCEEEEEEECCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHCCCHHHH
PHFVNEADLGKAGSRGKAAGEKVTGDPEKAFQDAEAVSDGVYGIPVVTHSCLEPHGCVIQ
HHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEECHHHHHHHCCCCCCEEE
WQGDQVMAWPSTQFVTGWANTLAPNLKVPAANIKVKMDYIGGGFGSKFSPGAWAEIGAIL
ECCCEEEECCCCCEEECHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHH
SQKAGGKPVKIYLDRVAEQTIAGNRPSAFGKIKVAGKKDGTITAWQSDTWASGGFAGGGQ
HHCCCCCCEEEHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCC
PPLPYVYTNIPNTRLNHTSISVNAGPSQAWRAPNNQQASYLTCSAIEDFAAKAGCDPMDV
CCCCEEEECCCCCEECCEEEEEECCCHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCHHHH
FHKNAGYTPRAEQYQYQLGKAAELSEWKKLWKPRGQQTGAVRRGLGIGVNAWAGNGHGCT
HHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCCEEEECCCCCCCE
SRVTINSDGSVLVEMGTQDLGTGTRTIMTQVAAETLGLSMGQVKLVIGDNSLPPGGSSGG
EEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
STTVGGVSSATRKAGINALAKLYEVAAPALGVQPDDLEAVDGNIRSKSNHAKTMTWAAAC
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHH
KKIPAAQGKIVETGANDTRNPMGLFSGGAAGVQVADVSVDTETGLVKINRFVAVQDCGLI
HHCCCCCCEEEECCCCCCCCCCCEECCCCCCEEEEEEEECCCCCEEEEEEEEEEECCCEE
INPRLAESQIFGAIIMGISTALFEERIMDNNTGRMMNPDLEFYKLAGIKDIGDIVVHLDI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEECCCCCCCCEEEEEEE
REVNDKRGVIGLGEPPAIGICAAVGNAVANAVGMRVPNMPMSPMNVLNTLEGRNA
EECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]