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The map label for this gene is cutM [H]

Identifier: 116621539

GI number: 116621539

Start: 3084343

End: 3085317

Strand: Direct

Name: cutM [H]

Synonym: Acid_2421

Alternate gene names: 116621539

Gene position: 3084343-3085317 (Clockwise)

Preceding gene: 116621538

Following gene: 116621542

Centisome position: 30.95

GC content: 64.82

Gene sequence:

>975_bases
ATGCAGTCGTTCGAATACGCCAATCCGGCGACCGTTCAGGAAGCGGTGGCGCTGCTCTCCGCCAAGTGGGGAGAGGCCGA
TGTACTGGCCGGCGGCACCGATCTCATCAGCCTGATGAAAGATCACCTTCACACGCCCAAGCGCGTGGTGAACATCAAGA
ACATCAAGGAACTGGAAGGTATCCAGAAAACCGCGACCGGGATTCGCATCGGCGCGCTGGTCACGATGGATGAGCTGGCG
AAGAACGCCGATGTGAAGGCTGCCGCGAAATCGCTGAGCGATGCGGCGGCCGGCATTCCGAGCCCGCAGATCCGCCACAT
GGGGACTGTGGGCGGCGATCTCTGCCAGCGTCCGCGCTGCTGGTATTACCGCCAGGGCTTCGGGCTGCTGGCCATGAAAG
ATGGCAAGAGCCTGGTGCCGGATGGCGCCAACCAGTATCACGCCATCTTCGGCGGCGGACCGGCGTATTTCGTCAGCGCC
AGCAGCCTCGGTCCCGCGCTGATTGCGCTGGGCGCCAAGGTGAAGCTGGTGTCGGCGAAGGGGCCGCGCGAAGTTCCGGC
GTCGGCATTCTTCGTGGTGCCGCAGAACGAAACCTCGCGTGAGATCGCGCTGCATCCCGACGAGATCCTCACGGAGATCG
TGATTCCGACGGCAACCGTCAAGAGCGCGACGTACGAAGTCCGGCAGAAGGAGGCGCTGGATTGGCCTCTGGCCGCGGCG
AGTGTCGTGCTCACCATGCGCGGCAACACCGTGGCGTCGGCCAAGGTGGTGCTCGGGCACGTCGGACCGAAACCGGTGGA
ATCGGCCGAAGCCGCCAAGGCGATCACGGGTAAAGCGATCACCGCCGATACCGCCGAGGCCGCGGGCAAGGCCGCAGTCG
CCGGAGCCACGCCGCTCAGCCAGAACGCTTATAAGGTTACGCTGGCGCGAGTGGCCGTGAAGCGCGCGCTGCTGGAGGCT
GCCAAGAAGGCATAG

Upstream 100 bases:

>100_bases
CCGTGGGCAACGCGGTGGCGAATGCGGTCGGCATGCGCGTACCGAATATGCCGATGTCTCCGATGAATGTGCTTAACACG
CTGGAAGGGAGGAACGCGTA

Downstream 100 bases:

>100_bases
ATATGGAACGGCCAGGGCTTACCAAAGTCAGTATGAATCGCTGCGAGAAGCTGCAGTGGAAGGGCATGTTCATCGATGCG
GAGTGGGATCCCACGATTCA

Product: molybdopterin dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit M; CO-DH M [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MQSFEYANPATVQEAVALLSAKWGEADVLAGGTDLISLMKDHLHTPKRVVNIKNIKELEGIQKTATGIRIGALVTMDELA
KNADVKAAAKSLSDAAAGIPSPQIRHMGTVGGDLCQRPRCWYYRQGFGLLAMKDGKSLVPDGANQYHAIFGGGPAYFVSA
SSLGPALIALGAKVKLVSAKGPREVPASAFFVVPQNETSREIALHPDEILTEIVIPTATVKSATYEVRQKEALDWPLAAA
SVVLTMRGNTVASAKVVLGHVGPKPVESAEAAKAITGKAITADTAEAAGKAAVAGATPLSQNAYKVTLARVAVKRALLEA
AKKA

Sequences:

>Translated_324_residues
MQSFEYANPATVQEAVALLSAKWGEADVLAGGTDLISLMKDHLHTPKRVVNIKNIKELEGIQKTATGIRIGALVTMDELA
KNADVKAAAKSLSDAAAGIPSPQIRHMGTVGGDLCQRPRCWYYRQGFGLLAMKDGKSLVPDGANQYHAIFGGGPAYFVSA
SSLGPALIALGAKVKLVSAKGPREVPASAFFVVPQNETSREIALHPDEILTEIVIPTATVKSATYEVRQKEALDWPLAAA
SVVLTMRGNTVASAKVVLGHVGPKPVESAEAAKAITGKAITADTAEAAGKAAVAGATPLSQNAYKVTLARVAVKRALLEA
AKKA
>Mature_324_residues
MQSFEYANPATVQEAVALLSAKWGEADVLAGGTDLISLMKDHLHTPKRVVNIKNIKELEGIQKTATGIRIGALVTMDELA
KNADVKAAAKSLSDAAAGIPSPQIRHMGTVGGDLCQRPRCWYYRQGFGLLAMKDGKSLVPDGANQYHAIFGGGPAYFVSA
SSLGPALIALGAKVKLVSAKGPREVPASAFFVVPQNETSREIALHPDEILTEIVIPTATVKSATYEVRQKEALDWPLAAA
SVVLTMRGNTVASAKVVLGHVGPKPVESAEAAKAITGKAITADTAEAAGKAAVAGATPLSQNAYKVTLARVAVKRALLEA
AKKA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786479, Length=340, Percent_Identity=28.8235294117647, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789231, Length=323, Percent_Identity=24.7678018575851, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 33795; Mature: 33795

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSFEYANPATVQEAVALLSAKWGEADVLAGGTDLISLMKDHLHTPKRVVNIKNIKELEG
CCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCHHEEEHHHHHHHHH
IQKTATGIRIGALVTMDELAKNADVKAAAKSLSDAAAGIPSPQIRHMGTVGGDLCQRPRC
HHHHHCCEEEEHEEEHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHCCCCC
WYYRQGFGLLAMKDGKSLVPDGANQYHAIFGGGPAYFVSASSLGPALIALGAKVKLVSAK
EEEECCCCEEEECCCCCCCCCCCCCEEEEECCCCEEEEECCCCCHHHEEECCEEEEEECC
GPREVPASAFFVVPQNETSREIALHPDEILTEIVIPTATVKSATYEVRQKEALDWPLAAA
CCCCCCCCEEEEEECCCCCCEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHE
SVVLTMRGNTVASAKVVLGHVGPKPVESAEAAKAITGKAITADTAEAAGKAAVAGATPLS
EEEEEECCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCEEECCCHHHCCCEEECCCCCCC
QNAYKVTLARVAVKRALLEAAKKA
CCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQSFEYANPATVQEAVALLSAKWGEADVLAGGTDLISLMKDHLHTPKRVVNIKNIKELEG
CCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCHHEEEHHHHHHHHH
IQKTATGIRIGALVTMDELAKNADVKAAAKSLSDAAAGIPSPQIRHMGTVGGDLCQRPRC
HHHHHCCEEEEHEEEHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHCCCCC
WYYRQGFGLLAMKDGKSLVPDGANQYHAIFGGGPAYFVSASSLGPALIALGAKVKLVSAK
EEEECCCCEEEECCCCCCCCCCCCCEEEEECCCCEEEEECCCCCHHHEEECCEEEEEECC
GPREVPASAFFVVPQNETSREIALHPDEILTEIVIPTATVKSATYEVRQKEALDWPLAAA
CCCCCCCCEEEEEECCCCCCEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHE
SVVLTMRGNTVASAKVVLGHVGPKPVESAEAAKAITGKAITADTAEAAGKAAVAGATPLS
EEEEEECCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCEEECCCHHHCCCEEECCCCCCC
QNAYKVTLARVAVKRALLEAAKKA
CCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]