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The map label for this gene is cutL [H]

Identifier: 116621345

GI number: 116621345

Start: 2848432

End: 2850762

Strand: Direct

Name: cutL [H]

Synonym: Acid_2226

Alternate gene names: 116621345

Gene position: 2848432-2850762 (Clockwise)

Preceding gene: 116621344

Following gene: 116621346

Centisome position: 28.58

GC content: 64.74

Gene sequence:

>2331_bases
ATGGCCACCACCACAACCAAACCCGAGACCCTCTTCGGCAAACGAGTTCGCCGCCAGGAGGACCCGCGGCTCATCACCGG
CACCGCGCTCTACCTGGACGATCTCAAGGTGCCAGGGATGCACCACGCCTGCATCGTCCGCAGTCCCCACGCCGCCGCTC
GCATCAGGGCCATCGAGACTCGCGCCGCGCTGGCCGCCCCCGGAGTGGTCGCCGTCTTCACCGGCGACGATATCAAGGAT
CTTGGACCGATCCCCTGCGCCGCCTCCCTTCCCGGTCTGCGCCGGCCGCATCACCACCTGCTTGCGCAGGATCGCGTCTA
TTTTGTCGGCCATGCCGTCGCCGTCGTGGTGGCTACCGACCGCTATCTTGCGCGCGACGCGGCTGACCTGGTCGAGGTCG
ATTATGAACGCCTCCCCGCCGTGGCCGACCCCGAAAAGGCGCTCGCGCCTTCCGCGCCCGCGGTCCATCCCCAGTGGCCC
GACAACATCGCGTTCAACTTCCATCAGGAGGGGGGCGACACGGAAAAGGCCTTCCGCGATGCCGATCTGGTGATTCGCCA
GCGCATCACCAGCCAGCGCCTGCTCCCCACCTCGATCGAAACTCGAGGCGTCCTGGCCGAGTGGCGCGCCGGCGAGAAAT
CGTTGACCTTGCATTCTTCCACCCAGATCCCGCACCTGCTGCGCTCCCTCTTGGCGGGCATCCTCGGCATGCCGGAGAAC
CGGCTGCGCGTGATCACGCCGGAGGTCGGCGGAGGCTTTGGAGCAAAGGCCGACGTCTATTGCGAAGACGCGCTCATGGC
CTTCATCGCGATGAGGATCAACAAGCCCGTCAAATGGGTGGAATCGCGCCGCGAGAATTACCAGGCCACCATACACGGCC
GCGGCCACGTCGATTACTTCGAACTCGCCGCGCGCCGCGACGGCACCATTCTCGGGCTCAAGCTGAAACTCATTCAGGAC
CTCGGCGCGTACCACCAGTTGCTCACGCCCATCATTCCCACTCTCTCCGTCCTCATGATGCCTGGCCTCTACCGCTTTCA
GAACGTCAGCGCGGACGTCGTCGGCGTCTTCACGAATTGCATGCCGACCGACGCGTACCGCGGCGCAGGACGTCCGGAAG
CCACTCATGGGATCGAGCGCATGGTGGATATGCTCGCCCAGGAATTGAAGATGGATCCGGCCGAGATCCGCCTCAAGAAC
TTCGTCCACGCCGATGAGTTCCCCTTTCCCACCGCAACCGGACTCTTGTACGATAGCGGCGATTACGCCAAGCCTCTGCA
CAAGGCGATGAACGAGGCCGGCTACCAGCAGCTGCGCCAGGAGCAGGCCGCCGCGCGCGCCGAGGGGCGCCTGGTGGGCA
TCGGCATTTCCACCTACGGCGAGATTTGCGCGCTGGGGCCATCGATCGCCCTCCCCGCCGGCGGCTGGGAATCCGCCACC
GTCAAGATCGAGCCCTCCGGCAAAGTCACCGTGCTCACCGGCTCGTCTCCCCACGGCCAGGGCGAGGAGACCACCTTCGC
GCAGATCGTCTCCGATGAACTCGGCGTACCCATGGACGACGTTCTCGTGGTCCATGGCGATACCGCCGTCGTGCAGTACG
GCATCGGCACCTTCGGCAGCCGCGGTACGGCGGTCGCCGGCACCGCCCTCTTCTACGCCCTCCAGGACATCAAGGCCAAG
ATGAAGAAGTTCGGCGCCATGATGCTGGGAACGGAGGATGTCAACTTTTCCGGCGGCCGCTGCGTGGATGAGACATGCGG
GAAATCCGTAACCTTCGCGGAAATGGCCACCGCCGCGCATCACGCCAAGCAACTTCCGCCCAATACGGCGCCGGGCCTGG
TAGCGACGCATTTCTGGGAGCCGCCGAATTTCACTTTCCCCTTCGGTGCGCACATCGTGGTCACCGAAGTCGATCGCGAG
ACCGGAGCGATCGAAATCCAACGCTACGTTTGCGTGGACGATATCGGCCGCATCATCAACCCGTTGATCGTGGATGGCCA
GGTGCACGGTGGAGTGGCGCAAGGGCTCGGCCAGGCGCTCTGGGAGCAGGCCGTCTACGACGACACGGGCCAATTGGTCA
GCGGCGAACTGACCGACTACGCGCTGCCAAAGGCGAGCGGGATGCCGTGGATCGAGAGCAGCCACACCGAGACGCCCTCT
CCCGTGAATCCGTTGGGAGTGAAGGGCGTTGGAGAGGCAGGCACCATCGGTTGTTCGCCCGCGGTCGTCAATTCGGTGGT
AGACGCGCTCGCGCCGCTGGGCGTGAAGCACATCGATATGCCGCTGACCCCGGAGAAAATCTGGAAGCTGATTCAGGAGG
CACGCGCATGA

Upstream 100 bases:

>100_bases
AGATCCGCCGCGGACTCGACGGAAATCTCTGCCGCTGCACCGGCTATCAGCACATCGTGAACGCCGTGAAATCCGCGGCC
AAAGCGGGAGGAGCCTGACC

Downstream 100 bases:

>100_bases
TCGCCAATCCGTTTACGTATCACAGCCCGGCCACTCTCGAGGAGGCCTTCACGATGCTGGAAGACGGCTCCGGCAAGATT
CTTGCCGGCGGCATGAGCCT

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 776; Mature: 775

Protein sequence:

>776_residues
MATTTTKPETLFGKRVRRQEDPRLITGTALYLDDLKVPGMHHACIVRSPHAAARIRAIETRAALAAPGVVAVFTGDDIKD
LGPIPCAASLPGLRRPHHHLLAQDRVYFVGHAVAVVVATDRYLARDAADLVEVDYERLPAVADPEKALAPSAPAVHPQWP
DNIAFNFHQEGGDTEKAFRDADLVIRQRITSQRLLPTSIETRGVLAEWRAGEKSLTLHSSTQIPHLLRSLLAGILGMPEN
RLRVITPEVGGGFGAKADVYCEDALMAFIAMRINKPVKWVESRRENYQATIHGRGHVDYFELAARRDGTILGLKLKLIQD
LGAYHQLLTPIIPTLSVLMMPGLYRFQNVSADVVGVFTNCMPTDAYRGAGRPEATHGIERMVDMLAQELKMDPAEIRLKN
FVHADEFPFPTATGLLYDSGDYAKPLHKAMNEAGYQQLRQEQAAARAEGRLVGIGISTYGEICALGPSIALPAGGWESAT
VKIEPSGKVTVLTGSSPHGQGEETTFAQIVSDELGVPMDDVLVVHGDTAVVQYGIGTFGSRGTAVAGTALFYALQDIKAK
MKKFGAMMLGTEDVNFSGGRCVDETCGKSVTFAEMATAAHHAKQLPPNTAPGLVATHFWEPPNFTFPFGAHIVVTEVDRE
TGAIEIQRYVCVDDIGRIINPLIVDGQVHGGVAQGLGQALWEQAVYDDTGQLVSGELTDYALPKASGMPWIESSHTETPS
PVNPLGVKGVGEAGTIGCSPAVVNSVVDALAPLGVKHIDMPLTPEKIWKLIQEARA

Sequences:

>Translated_776_residues
MATTTTKPETLFGKRVRRQEDPRLITGTALYLDDLKVPGMHHACIVRSPHAAARIRAIETRAALAAPGVVAVFTGDDIKD
LGPIPCAASLPGLRRPHHHLLAQDRVYFVGHAVAVVVATDRYLARDAADLVEVDYERLPAVADPEKALAPSAPAVHPQWP
DNIAFNFHQEGGDTEKAFRDADLVIRQRITSQRLLPTSIETRGVLAEWRAGEKSLTLHSSTQIPHLLRSLLAGILGMPEN
RLRVITPEVGGGFGAKADVYCEDALMAFIAMRINKPVKWVESRRENYQATIHGRGHVDYFELAARRDGTILGLKLKLIQD
LGAYHQLLTPIIPTLSVLMMPGLYRFQNVSADVVGVFTNCMPTDAYRGAGRPEATHGIERMVDMLAQELKMDPAEIRLKN
FVHADEFPFPTATGLLYDSGDYAKPLHKAMNEAGYQQLRQEQAAARAEGRLVGIGISTYGEICALGPSIALPAGGWESAT
VKIEPSGKVTVLTGSSPHGQGEETTFAQIVSDELGVPMDDVLVVHGDTAVVQYGIGTFGSRGTAVAGTALFYALQDIKAK
MKKFGAMMLGTEDVNFSGGRCVDETCGKSVTFAEMATAAHHAKQLPPNTAPGLVATHFWEPPNFTFPFGAHIVVTEVDRE
TGAIEIQRYVCVDDIGRIINPLIVDGQVHGGVAQGLGQALWEQAVYDDTGQLVSGELTDYALPKASGMPWIESSHTETPS
PVNPLGVKGVGEAGTIGCSPAVVNSVVDALAPLGVKHIDMPLTPEKIWKLIQEARA
>Mature_775_residues
ATTTTKPETLFGKRVRRQEDPRLITGTALYLDDLKVPGMHHACIVRSPHAAARIRAIETRAALAAPGVVAVFTGDDIKDL
GPIPCAASLPGLRRPHHHLLAQDRVYFVGHAVAVVVATDRYLARDAADLVEVDYERLPAVADPEKALAPSAPAVHPQWPD
NIAFNFHQEGGDTEKAFRDADLVIRQRITSQRLLPTSIETRGVLAEWRAGEKSLTLHSSTQIPHLLRSLLAGILGMPENR
LRVITPEVGGGFGAKADVYCEDALMAFIAMRINKPVKWVESRRENYQATIHGRGHVDYFELAARRDGTILGLKLKLIQDL
GAYHQLLTPIIPTLSVLMMPGLYRFQNVSADVVGVFTNCMPTDAYRGAGRPEATHGIERMVDMLAQELKMDPAEIRLKNF
VHADEFPFPTATGLLYDSGDYAKPLHKAMNEAGYQQLRQEQAAARAEGRLVGIGISTYGEICALGPSIALPAGGWESATV
KIEPSGKVTVLTGSSPHGQGEETTFAQIVSDELGVPMDDVLVVHGDTAVVQYGIGTFGSRGTAVAGTALFYALQDIKAKM
KKFGAMMLGTEDVNFSGGRCVDETCGKSVTFAEMATAAHHAKQLPPNTAPGLVATHFWEPPNFTFPFGAHIVVTEVDRET
GAIEIQRYVCVDDIGRIINPLIVDGQVHGGVAQGLGQALWEQAVYDDTGQLVSGELTDYALPKASGMPWIESSHTETPSP
VNPLGVKGVGEAGTIGCSPAVVNSVVDALAPLGVKHIDMPLTPEKIWKLIQEARA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=777, Percent_Identity=24.7104247104247, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI91823271, Length=773, Percent_Identity=24.1914618369987, Blast_Score=160, Evalue=4e-39,
Organism=Escherichia coli, GI1789230, Length=764, Percent_Identity=30.6282722513089, Blast_Score=281, Evalue=2e-76,
Organism=Escherichia coli, GI1789246, Length=819, Percent_Identity=27.7167277167277, Blast_Score=262, Evalue=6e-71,
Organism=Escherichia coli, GI1786478, Length=763, Percent_Identity=26.867627785059, Blast_Score=171, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17540638, Length=711, Percent_Identity=24.3319268635724, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17539860, Length=780, Percent_Identity=23.3333333333333, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI32566215, Length=803, Percent_Identity=21.7932752179328, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17737937, Length=734, Percent_Identity=24.7956403269755, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24647193, Length=725, Percent_Identity=25.1034482758621, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24647197, Length=777, Percent_Identity=23.6808236808237, Blast_Score=118, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24647195, Length=777, Percent_Identity=23.6808236808237, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 83684; Mature: 83552

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTTTKPETLFGKRVRRQEDPRLITGTALYLDDLKVPGMHHACIVRSPHAAARIRAIET
CCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHH
RAALAAPGVVAVFTGDDIKDLGPIPCAASLPGLRRPHHHLLAQDRVYFVGHAVAVVVATD
HHHHCCCCEEEEEECCCHHHCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEEEEEEECC
RYLARDAADLVEVDYERLPAVADPEKALAPSAPAVHPQWPDNIAFNFHQEGGDTEKAFRD
HHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHH
ADLVIRQRITSQRLLPTSIETRGVLAEWRAGEKSLTLHSSTQIPHLLRSLLAGILGMPEN
HHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCC
RLRVITPEVGGGFGAKADVYCEDALMAFIAMRINKPVKWVESRRENYQATIHGRGHVDYF
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCCHHH
ELAARRDGTILGLKLKLIQDLGAYHQLLTPIIPTLSVLMMPGLYRFQNVSADVVGVFTNC
HHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHC
MPTDAYRGAGRPEATHGIERMVDMLAQELKMDPAEIRLKNFVHADEFPFPTATGLLYDSG
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEECCC
DYAKPLHKAMNEAGYQQLRQEQAAARAEGRLVGIGISTYGEICALGPSIALPAGGWESAT
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCEECCCCCCCCEE
VKIEPSGKVTVLTGSSPHGQGEETTFAQIVSDELGVPMDDVLVVHGDTAVVQYGIGTFGS
EEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHEEEEECCCEEEEECCCCCCC
RGTAVAGTALFYALQDIKAKMKKFGAMMLGTEDVNFSGGRCVDETCGKSVTFAEMATAAH
CCCHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCEECHHHCCCCEEHHHHHHHHH
HAKQLPPNTAPGLVATHFWEPPNFTFPFGAHIVVTEVDRETGAIEIQRYVCVDDIGRIIN
HHHHCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEHHHHHHHHC
PLIVDGQVHGGVAQGLGQALWEQAVYDDTGQLVSGELTDYALPKASGMPWIESSHTETPS
CEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCHHHCCCCCCCCCCCCCCCCCCCC
PVNPLGVKGVGEAGTIGCSPAVVNSVVDALAPLGVKHIDMPLTPEKIWKLIQEARA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ATTTTKPETLFGKRVRRQEDPRLITGTALYLDDLKVPGMHHACIVRSPHAAARIRAIET
CCCCCCCHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHH
RAALAAPGVVAVFTGDDIKDLGPIPCAASLPGLRRPHHHLLAQDRVYFVGHAVAVVVATD
HHHHCCCCEEEEEECCCHHHCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEEEEEEECC
RYLARDAADLVEVDYERLPAVADPEKALAPSAPAVHPQWPDNIAFNFHQEGGDTEKAFRD
HHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHH
ADLVIRQRITSQRLLPTSIETRGVLAEWRAGEKSLTLHSSTQIPHLLRSLLAGILGMPEN
HHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCC
RLRVITPEVGGGFGAKADVYCEDALMAFIAMRINKPVKWVESRRENYQATIHGRGHVDYF
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCCHHH
ELAARRDGTILGLKLKLIQDLGAYHQLLTPIIPTLSVLMMPGLYRFQNVSADVVGVFTNC
HHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHC
MPTDAYRGAGRPEATHGIERMVDMLAQELKMDPAEIRLKNFVHADEFPFPTATGLLYDSG
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEECCC
DYAKPLHKAMNEAGYQQLRQEQAAARAEGRLVGIGISTYGEICALGPSIALPAGGWESAT
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCEECCCCCCCCEE
VKIEPSGKVTVLTGSSPHGQGEETTFAQIVSDELGVPMDDVLVVHGDTAVVQYGIGTFGS
EEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHEEEEECCCEEEEECCCCCCC
RGTAVAGTALFYALQDIKAKMKKFGAMMLGTEDVNFSGGRCVDETCGKSVTFAEMATAAH
CCCHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCEECHHHCCCCEEHHHHHHHHH
HAKQLPPNTAPGLVATHFWEPPNFTFPFGAHIVVTEVDRETGAIEIQRYVCVDDIGRIIN
HHHHCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEHHHHHHHHC
PLIVDGQVHGGVAQGLGQALWEQAVYDDTGQLVSGELTDYALPKASGMPWIESSHTETPS
CEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCHHHCCCCCCCCCCCCCCCCCCCC
PVNPLGVKGVGEAGTIGCSPAVVNSVVDALAPLGVKHIDMPLTPEKIWKLIQEARA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]