Click here to switch to the map view.

The map label for this gene is cutM [H]

Identifier: 116621346

GI number: 116621346

Start: 2850759

End: 2851604

Strand: Direct

Name: cutM [H]

Synonym: Acid_2227

Alternate gene names: 116621346

Gene position: 2850759-2851604 (Clockwise)

Preceding gene: 116621345

Following gene: 116621347

Centisome position: 28.61

GC content: 66.08

Gene sequence:

>846_bases
ATGATCGCCAATCCGTTTACGTATCACAGCCCGGCCACTCTCGAGGAGGCCTTCACGATGCTGGAAGACGGCTCCGGCAA
GATTCTTGCCGGCGGCATGAGCCTGATTCCTCTGATGAAGCTGCGGCTGGCCTCGCCCGATAGCGTGATCGATCTACGCC
GCATTCCGGGGCTCAAGGCAATCAGCGAGTCGGATGGCGTGGTGCGCGTGGGCGCGATGGCGACGCATCACGAGATCGAG
ACTTCGCCGGTGATCCGCGGCAAGTGTCCGCTGCTGGGCGAAGCCGCCAGTGAGATCGGTGACATCCAGGTGCGCAACAT
GGGCACCATCGGCGGCAGCGTGGCGCATGCCGATCCCGCGGCCGATTACCCGGCCGCACTGATCGCCCTCGAAGCGCGGA
TTCGTCTGCGCTCGGCGCAAGGCGAGCGGACGGTGGAGGCGAGCGAGTTTTTCCTGGACGCCTTCACCACAGCGATCGAG
CCCGGCGAAATCGTGGTCGCCGTCGAGATTGCCGCCGAGGAATCTAGCGAAGGCTACAAATACGAGAAGGTTCCGCACCC
GGCCTCGGGCTTCCCGGTTGTGGGCGTTGCGGTGCGCGTGAAGAAATCGGGTACGGGAATTTCGATGGCGCGCATCGGCG
TCACCGGCATGGGGCCGCACGCATTCCGCGCGCGGAATGCCGAGGCATTGCTGCAAGAGGCAGCGGGAACGGCCGCCGCG
GCCGCGGTGGTTGGCGAGGGCGAAGAGACGAACTCGGACCTGTACGCGAGCGGTGAATACCGCCGCCATCTGGCGCGCGT
CTACGCGGCGCGCGCTATCGCAGCGGCCCTGACGAGGGCCTCGTGA

Upstream 100 bases:

>100_bases
TCAATTCGGTGGTAGACGCGCTCGCGCCGCTGGGCGTGAAGCACATCGATATGCCGCTGACCCCGGAGAAAATCTGGAAG
CTGATTCAGGAGGCACGCGC

Downstream 100 bases:

>100_bases
AGGTCGGGGGAACGTTTCCGATTCCCTTCCCGCAGGATGTTGCTTACCGTCTCCTCCAGGATCCCGCGGTGCTCTGCCGC
TGCATGCCGGGCTGCGAGGA

Product: molybdopterin dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit M; CO-DH M [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MIANPFTYHSPATLEEAFTMLEDGSGKILAGGMSLIPLMKLRLASPDSVIDLRRIPGLKAISESDGVVRVGAMATHHEIE
TSPVIRGKCPLLGEAASEIGDIQVRNMGTIGGSVAHADPAADYPAALIALEARIRLRSAQGERTVEASEFFLDAFTTAIE
PGEIVVAVEIAAEESSEGYKYEKVPHPASGFPVVGVAVRVKKSGTGISMARIGVTGMGPHAFRARNAEALLQEAAGTAAA
AAVVGEGEETNSDLYASGEYRRHLARVYAARAIAAALTRAS

Sequences:

>Translated_281_residues
MIANPFTYHSPATLEEAFTMLEDGSGKILAGGMSLIPLMKLRLASPDSVIDLRRIPGLKAISESDGVVRVGAMATHHEIE
TSPVIRGKCPLLGEAASEIGDIQVRNMGTIGGSVAHADPAADYPAALIALEARIRLRSAQGERTVEASEFFLDAFTTAIE
PGEIVVAVEIAAEESSEGYKYEKVPHPASGFPVVGVAVRVKKSGTGISMARIGVTGMGPHAFRARNAEALLQEAAGTAAA
AAVVGEGEETNSDLYASGEYRRHLARVYAARAIAAALTRAS
>Mature_281_residues
MIANPFTYHSPATLEEAFTMLEDGSGKILAGGMSLIPLMKLRLASPDSVIDLRRIPGLKAISESDGVVRVGAMATHHEIE
TSPVIRGKCPLLGEAASEIGDIQVRNMGTIGGSVAHADPAADYPAALIALEARIRLRSAQGERTVEASEFFLDAFTTAIE
PGEIVVAVEIAAEESSEGYKYEKVPHPASGFPVVGVAVRVKKSGTGISMARIGVTGMGPHAFRARNAEALLQEAAGTAAA
AAVVGEGEETNSDLYASGEYRRHLARVYAARAIAAALTRAS

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789231, Length=279, Percent_Identity=24.3727598566308, Blast_Score=88, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 29365; Mature: 29365

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIANPFTYHSPATLEEAFTMLEDGSGKILAGGMSLIPLMKLRLASPDSVIDLRRIPGLKA
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCCEEHHHHCCCCCE
ISESDGVVRVGAMATHHEIETSPVIRGKCPLLGEAASEIGDIQVRNMGTIGGSVAHADPA
ECCCCCEEEECCEEECCCCCCCCEECCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCCCC
ADYPAALIALEARIRLRSAQGERTVEASEFFLDAFTTAIEPGEIVVAVEIAAEESSEGYK
CCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCE
YEKVPHPASGFPVVGVAVRVKKSGTGISMARIGVTGMGPHAFRARNAEALLQEAAGTAAA
ECCCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCHHHHHCCHHHHHHHHCCCHHH
AAVVGEGEETNSDLYASGEYRRHLARVYAARAIAAALTRAS
HEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIANPFTYHSPATLEEAFTMLEDGSGKILAGGMSLIPLMKLRLASPDSVIDLRRIPGLKA
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCCEEHHHHCCCCCE
ISESDGVVRVGAMATHHEIETSPVIRGKCPLLGEAASEIGDIQVRNMGTIGGSVAHADPA
ECCCCCEEEECCEEECCCCCCCCEECCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCCCC
ADYPAALIALEARIRLRSAQGERTVEASEFFLDAFTTAIEPGEIVVAVEIAAEESSEGYK
CCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCE
YEKVPHPASGFPVVGVAVRVKKSGTGISMARIGVTGMGPHAFRARNAEALLQEAAGTAAA
ECCCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCHHHHHCCHHHHHHHHCCCHHH
AAVVGEGEETNSDLYASGEYRRHLARVYAARAIAAALTRAS
HEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]