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The map label for this gene is cutS [H]

Identifier: 116621344

GI number: 116621344

Start: 2847929

End: 2848429

Strand: Direct

Name: cutS [H]

Synonym: Acid_2225

Alternate gene names: 116621344

Gene position: 2847929-2848429 (Clockwise)

Preceding gene: 116621342

Following gene: 116621345

Centisome position: 28.58

GC content: 61.28

Gene sequence:

>501_bases
GTGTCTATTCGCTGGGTCACGGATGCGTACATGAAACAGAAACTCACACTTACCATCAACGGGAAGCCCTATTCGGACGA
GGTCGAACCTCGACTGCTTTTGATCCACTATCTGCGCGAAGTGGCCGGGCTCACCGGGCCGCACATTGGCTGCGAAACGT
CGATCTGCGGAGCCTGCACGGTCATGCTGGATGGCATGGCCGTCAAGAGCTGCACCATCTTTGCCGTCCAGGCCGAGGGG
CGCAGCGTGCTGACTATCGAGGGGCTTGCCCAAAACGGCAAACTCGATCCCCTGCAGGAGGCGTTCTGGAACGAACACGC
CCTGCAGTGCGGGTTCTGCACTCCGGGCATGATTCTCACCGCGCGGCAGTTGCTGGCCGATAATCCGAGCCCCACCGAGC
AGGAGATCCGCCGCGGACTCGACGGAAATCTCTGCCGCTGCACCGGCTATCAGCACATCGTGAACGCCGTGAAATCCGCG
GCCAAAGCGGGAGGAGCCTGA

Upstream 100 bases:

>100_bases
GTGCGAGGGTCGCCAGCGTATATTCGCGGTCGATTTTCATTGGACTCCAATGCGATGGTACTAAACACCCTGCCGTAGCC
GAGCGGCGGTTTTTTTGATA

Downstream 100 bases:

>100_bases
CCATGGCCACCACCACAACCAAACCCGAGACCCTCTTCGGCAAACGAGTTCGCCGCCAGGAGGACCCGCGGCTCATCACC
GGCACCGCGCTCTACCTGGA

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MSIRWVTDAYMKQKLTLTINGKPYSDEVEPRLLLIHYLREVAGLTGPHIGCETSICGACTVMLDGMAVKSCTIFAVQAEG
RSVLTIEGLAQNGKLDPLQEAFWNEHALQCGFCTPGMILTARQLLADNPSPTEQEIRRGLDGNLCRCTGYQHIVNAVKSA
AKAGGA

Sequences:

>Translated_166_residues
MSIRWVTDAYMKQKLTLTINGKPYSDEVEPRLLLIHYLREVAGLTGPHIGCETSICGACTVMLDGMAVKSCTIFAVQAEG
RSVLTIEGLAQNGKLDPLQEAFWNEHALQCGFCTPGMILTARQLLADNPSPTEQEIRRGLDGNLCRCTGYQHIVNAVKSA
AKAGGA
>Mature_165_residues
SIRWVTDAYMKQKLTLTINGKPYSDEVEPRLLLIHYLREVAGLTGPHIGCETSICGACTVMLDGMAVKSCTIFAVQAEGR
SVLTIEGLAQNGKLDPLQEAFWNEHALQCGFCTPGMILTARQLLADNPSPTEQEIRRGLDGNLCRCTGYQHIVNAVKSAA
KAGGA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=161, Percent_Identity=36.0248447204969, Blast_Score=94, Evalue=6e-20,
Organism=Homo sapiens, GI71773480, Length=164, Percent_Identity=37.1951219512195, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=49.6598639455782, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1786480, Length=175, Percent_Identity=36.5714285714286, Blast_Score=112, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32566215, Length=163, Percent_Identity=38.6503067484663, Blast_Score=127, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17539860, Length=156, Percent_Identity=39.1025641025641, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17540638, Length=164, Percent_Identity=39.6341463414634, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI17737937, Length=160, Percent_Identity=35, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=35.7142857142857, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=34.8387096774194, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24647193, Length=162, Percent_Identity=34.5679012345679, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=29.6296296296296, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=29.6296296296296, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17966; Mature: 17835

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRWVTDAYMKQKLTLTINGKPYSDEVEPRLLLIHYLREVAGLTGPHIGCETSICGACT
CCEEEECHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
VMLDGMAVKSCTIFAVQAEGRSVLTIEGLAQNGKLDPLQEAFWNEHALQCGFCTPGMILT
HHHCCEEECEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHCCCCCEEECCCCCCHHHH
ARQLLADNPSPTEQEIRRGLDGNLCRCTGYQHIVNAVKSAAKAGGA
HHHHHCCCCCCCHHHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SIRWVTDAYMKQKLTLTINGKPYSDEVEPRLLLIHYLREVAGLTGPHIGCETSICGACT
CEEEECHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
VMLDGMAVKSCTIFAVQAEGRSVLTIEGLAQNGKLDPLQEAFWNEHALQCGFCTPGMILT
HHHCCEEECEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHCCCCCEEECCCCCCHHHH
ARQLLADNPSPTEQEIRRGLDGNLCRCTGYQHIVNAVKSAAKAGGA
HHHHHCCCCCCCHHHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]