BacMap

Definition	Candidatus Solibacter usitatus Ellin6076 chromosome, complete genome.
Accession	NC_008536
Length	9,965,640

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The map label for this gene is kduD [H]

Identifier: 116621342

GI number: 116621342

Start: 2845893

End: 2846663

Strand: Direct

Name: kduD [H]

Synonym: Acid_2223

Alternate gene names: 116621342

Gene position: 2845893-2846663 (Clockwise)

Preceding gene: 116621341

Following gene: 116621344

Centisome position: 28.56

GC content: 64.46

Gene sequence:

>771_bases
GTGAGCATACTCGATAAATTCAAGGTGAGCGGTAAGACCGCACTCGTCACCGGCGCCCGTCGCGGCATCGGCAAGGCAAT
GGCGGTGGCCCTGGCGGAAGCCGGCGCGGACATCGTGGCGACCAGCGCGGAGATGGAAGGCGAAGGCAGCGCCGTGGCCA
AAGAGGTCGCAGCGCTGGGACGGAAGTGTTGGACGTACGCCTGCGATCTGGCCGATCGCAAAGCCGTCTACGCGTTCATC
GAAAAGGTGAAGCGCGAGTGCCCGCCGGTGGACATTCTGGTCAATAACGGCGGCTCGATTCTGCGCAAGCCGGCGGCCGA
ACATCCGGATGAATTTTGGGACAAGATCATCGAGATCGATCTCAACGCGCAGTTCGTGCTCGCGCGCGAATTCGGGCGCG
ACATGCTGGAGCGCGGCGGAGGCAAGATCGTCTTCACCGCATCGCTCTTGAGTTTTCAGGGCGGCATTACGGTGCCTGGG
TACGCGGCGGCCAAGGGCGGTGTCGCGCAGTTGACCAAGGCGCTGGCGAATGAGTGGGCGGGCAGGAATGTGCAGGTGAA
CGCGATCGCCCCCGGCTACATCGCTACCGACAATACGACGGCCTTGCGCGCCGATGCGTCACGCAATATCGCGATCCTCG
CACGCATTCCGGCGGGTCGATGGGGCGATGCCGAAGATCTCGCGGGCGCCGTGGTTTACCTCGCGTCGCCCGCCTCGGAC
TACGTCAGCGGCACGGTGATAACGGTGGACGGCGGCTGGATGGGCCGGTAG

Upstream 100 bases:

>100_bases
ACGGACGTGCTGCCCCTCAGCCGGCTGGAAGAAGCCATGCACCGGATGGAGCGCGGCGGCGACTGCATGAAGATCCTGGT
AAGTTGTACGGACTAATTAC

Downstream 100 bases:

>100_bases
ACGAGGCCTCCCGGCCGTACCGCGAGATCGCTTGGTAATTTGCTTGGAGGCCGTCACCCGCAGTAATCGATCGCGGCCTC
AGCCAGAATCTCGGCGAGTT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MSILDKFKVSGKTALVTGARRGIGKAMAVALAEAGADIVATSAEMEGEGSAVAKEVAALGRKCWTYACDLADRKAVYAFI
EKVKRECPPVDILVNNGGSILRKPAAEHPDEFWDKIIEIDLNAQFVLAREFGRDMLERGGGKIVFTASLLSFQGGITVPG
YAAAKGGVAQLTKALANEWAGRNVQVNAIAPGYIATDNTTALRADASRNIAILARIPAGRWGDAEDLAGAVVYLASPASD
YVSGTVITVDGGWMGR

Sequences:

>Translated_256_residues
MSILDKFKVSGKTALVTGARRGIGKAMAVALAEAGADIVATSAEMEGEGSAVAKEVAALGRKCWTYACDLADRKAVYAFI
EKVKRECPPVDILVNNGGSILRKPAAEHPDEFWDKIIEIDLNAQFVLAREFGRDMLERGGGKIVFTASLLSFQGGITVPG
YAAAKGGVAQLTKALANEWAGRNVQVNAIAPGYIATDNTTALRADASRNIAILARIPAGRWGDAEDLAGAVVYLASPASD
YVSGTVITVDGGWMGR
>Mature_255_residues
SILDKFKVSGKTALVTGARRGIGKAMAVALAEAGADIVATSAEMEGEGSAVAKEVAALGRKCWTYACDLADRKAVYAFIE
KVKRECPPVDILVNNGGSILRKPAAEHPDEFWDKIIEIDLNAQFVLAREFGRDMLERGGGKIVFTASLLSFQGGITVPGY
AAAKGGVAQLTKALANEWAGRNVQVNAIAPGYIATDNTTALRADASRNIAILARIPAGRWGDAEDLAGAVVYLASPASDY
VSGTVITVDGGWMGR

Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=264, Percent_Identity=31.8181818181818, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=30.1652892561983, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=29.6442687747036, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=30.4878048780488, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=31.0483870967742, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=30.5555555555556, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=29.5275590551181, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=28.6852589641434, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4503301, Length=254, Percent_Identity=28.3464566929134, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=27.7777777777778, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI209862901, Length=197, Percent_Identity=31.4720812182741, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI19923983, Length=197, Percent_Identity=31.4720812182741, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI31542939, Length=197, Percent_Identity=31.4720812182741, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI25282469, Length=194, Percent_Identity=28.8659793814433, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4504505, Length=259, Percent_Identity=27.4131274131274, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI33667109, Length=206, Percent_Identity=28.1553398058252, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI142976729, Length=194, Percent_Identity=29.3814432989691, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI310128830, Length=200, Percent_Identity=28, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI310115468, Length=200, Percent_Identity=28, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI59889578, Length=194, Percent_Identity=29.8969072164948, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI40807363, Length=193, Percent_Identity=26.4248704663212, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI126723191, Length=197, Percent_Identity=29.4416243654822, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI210032110, Length=194, Percent_Identity=25.7731958762887, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI225579078, Length=207, Percent_Identity=29.951690821256, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI226371731, Length=199, Percent_Identity=29.6482412060301, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI109715829, Length=240, Percent_Identity=27.9166666666667, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI83715985, Length=256, Percent_Identity=28.125, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI20149619, Length=203, Percent_Identity=28.0788177339901, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=30.2857142857143, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=46.6666666666667, Blast_Score=231, Evalue=3e-62,
Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=40.7843137254902, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=37.2, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=38.0566801619433, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=32.4, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=31.4516129032258, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=31.8897637795276, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=31.9838056680162, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=30.3643724696356, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=30.1204819277108, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=29.3650793650794, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787526, Length=201, Percent_Identity=26.865671641791, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=24.609375, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=28.2608695652174, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=33.8775510204082, Blast_Score=127, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17561402, Length=263, Percent_Identity=32.6996197718631, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=31.2977099236641, Blast_Score=113, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=30.4878048780488, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=33.8541666666667, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=26.9076305220884, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI193203115, Length=190, Percent_Identity=33.1578947368421, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17564282, Length=197, Percent_Identity=29.9492385786802, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=30.1158301158301, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=29.296875, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17561272, Length=253, Percent_Identity=32.0158102766798, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=28.2258064516129, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=26.8199233716475, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=28.3018867924528, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=27.906976744186, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=27.5862068965517, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=26.8199233716475, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=28.957528957529, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=27.9527559055118, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=27.906976744186, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=26.3565891472868, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=27.5862068965517, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=27.6119402985075, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=25.2788104089219, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=266, Percent_Identity=30.4511278195489, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71997099, Length=206, Percent_Identity=31.0679611650485, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=26.0700389105058, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=24.2424242424242, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=25.1908396946565, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=29.9595141700405, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=26.3358778625954, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=27.2030651340996, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=25.1908396946565, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=25.2873563218391, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI86565303, Length=279, Percent_Identity=27.9569892473118, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=216, Percent_Identity=28.7037037037037, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=196, Percent_Identity=29.5918367346939, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=30.859375, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322861, Length=188, Percent_Identity=29.7872340425532, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=31.6205533596838, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=30.5220883534137, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=31.1740890688259, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24640492, Length=192, Percent_Identity=30.7291666666667, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21358495, Length=202, Percent_Identity=29.2079207920792, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI23397609, Length=263, Percent_Identity=26.615969581749, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=28.125, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=29.2682926829268, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=26.8292682926829, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24584748, Length=199, Percent_Identity=33.1658291457286, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161076933, Length=199, Percent_Identity=33.1658291457286, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281364892, Length=170, Percent_Identity=27.0588235294118, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24584744, Length=201, Percent_Identity=31.3432835820896, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28574402, Length=201, Percent_Identity=32.8358208955224, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24581726, Length=198, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24580925, Length=197, Percent_Identity=29.9492385786802, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355631, Length=179, Percent_Identity=30.1675977653631, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737361, Length=260, Percent_Identity=28.8461538461538, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI18859837, Length=195, Percent_Identity=28.7179487179487, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011286
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.127 [H]

Molecular weight: Translated: 26873; Mature: 26742

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS00061 ADH_SHORT ; PS00074 GLFV_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILDKFKVSGKTALVTGARRGIGKAMAVALAEAGADIVATSAEMEGEGSAVAKEVAALG
CCCHHHHHCCCCEEEEECCHHCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHH
RKCWTYACDLADRKAVYAFIEKVKRECPPVDILVNNGGSILRKPAAEHPDEFWDKIIEID
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCCCHHHHHHHEEEC
LNAQFVLAREFGRDMLERGGGKIVFTASLLSFQGGITVPGYAAAKGGVAQLTKALANEWA
CCCEEEEHHHHCHHHHHCCCCEEEEEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHHHC
GRNVQVNAIAPGYIATDNTTALRADASRNIAILARIPAGRWGDAEDLAGAVVYLASPASD
CCCEEEEEECCCEEECCCCEEEEECCCCCEEEEEECCCCCCCCHHHHCCEEEEEECCCHH
YVSGTVITVDGGWMGR
HHCCEEEEECCCCCCC
>Mature Secondary Structure 
SILDKFKVSGKTALVTGARRGIGKAMAVALAEAGADIVATSAEMEGEGSAVAKEVAALG
CCHHHHHCCCCEEEEECCHHCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHH
RKCWTYACDLADRKAVYAFIEKVKRECPPVDILVNNGGSILRKPAAEHPDEFWDKIIEID
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCCCHHHHHHHEEEC
LNAQFVLAREFGRDMLERGGGKIVFTASLLSFQGGITVPGYAAAKGGVAQLTKALANEWA
CCCEEEEHHHHCHHHHHCCCCEEEEEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHHHC
GRNVQVNAIAPGYIATDNTTALRADASRNIAILARIPAGRWGDAEDLAGAVVYLASPASD
CCCEEEEEECCCEEECCCCEEEEECCCCCEEEEEECCCCCCCCHHHHCCEEEEEECCCHH
YVSGTVITVDGGWMGR
HHCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]