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The map label for this gene is yxjL [H]

Identifier: 116620723

GI number: 116620723

Start: 1976513

End: 1977163

Strand: Reverse

Name: yxjL [H]

Synonym: Acid_1603

Alternate gene names: 116620723

Gene position: 1977163-1976513 (Counterclockwise)

Preceding gene: 116620724

Following gene: 116620720

Centisome position: 19.84

GC content: 58.99

Gene sequence:

>651_bases
ATGAAGACAATCCGCATTCTTCTCGCCGACGATCACACTGTGGTTCGCAAAGGCTTGCGCCTGCTGCTCGAAAGCCATCC
CGGATTTCAGGTCATCGGCGACGCCGCCGATGGGCGCGATGCCGTTTCCCTGGCAGGAGAGCACACGCCCGATGTCGTGG
TGATGGACGTCGCCATGCCGGGATTGAACGGCATCGAGGCCGCGCGCCAGATCTCCGCCAAACTGCCCCACACCGCGATC
GTGTTTCTCAGTATGCACTCCGATGAGAGCTACGTGCTCAAGGCTCTTAAGGCCGGTGCGCGCGCTTACCTGCTCAAGGA
CTCGGCCGAACACGACCTGATCGCCGCGGTGATCGCAGTCAGCGAAGGCAAAGCCTTCTTCAGCCCCGCCATCAGCAAAA
TGCTGGTCGAAGATTATATGCGCCAGATGCAGGAGCGCCAGATTGAAGACAGCTACGAGCTTCTTACCACGCGGGAGCGT
GAAGTGCTGCAGCTGCTGGCCGAAGGCAAGAACAATAAGGAAGTCGCGGCCATCCTCAATCTGAGCCTGTACACCGTGGA
AACCCACCGCGGCAACATTCTGCAAAAACTCAACCTGCATAGCGGCGCCGAACTCATCCTCTATGCCATCCGCAAAGGCG
TGATCAGCTGA

Upstream 100 bases:

>100_bases
AGGAACGGGTGGGCTATCTCGGCGGTAAGTTCGAGGTGGGCTCGGCGCCCGGCAAGGGTACCGCGCTCAAAGTGACCCTT
CCCCTGGTTCGCAAATACGC

Downstream 100 bases:

>100_bases
GGCGCGAACCGCGACCGTCAGGGAGCGATCTCTTGACTCCCGACGGCACTCCGACCACATCCTCTACCGCTTGGCGGGCG
CCGAGGCCTTCACCGCCCGT

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKTIRILLADDHTVVRKGLRLLLESHPGFQVIGDAADGRDAVSLAGEHTPDVVVMDVAMPGLNGIEAARQISAKLPHTAI
VFLSMHSDESYVLKALKAGARAYLLKDSAEHDLIAAVIAVSEGKAFFSPAISKMLVEDYMRQMQERQIEDSYELLTTRER
EVLQLLAEGKNNKEVAAILNLSLYTVETHRGNILQKLNLHSGAELILYAIRKGVIS

Sequences:

>Translated_216_residues
MKTIRILLADDHTVVRKGLRLLLESHPGFQVIGDAADGRDAVSLAGEHTPDVVVMDVAMPGLNGIEAARQISAKLPHTAI
VFLSMHSDESYVLKALKAGARAYLLKDSAEHDLIAAVIAVSEGKAFFSPAISKMLVEDYMRQMQERQIEDSYELLTTRER
EVLQLLAEGKNNKEVAAILNLSLYTVETHRGNILQKLNLHSGAELILYAIRKGVIS
>Mature_216_residues
MKTIRILLADDHTVVRKGLRLLLESHPGFQVIGDAADGRDAVSLAGEHTPDVVVMDVAMPGLNGIEAARQISAKLPHTAI
VFLSMHSDESYVLKALKAGARAYLLKDSAEHDLIAAVIAVSEGKAFFSPAISKMLVEDYMRQMQERQIEDSYELLTTRER
EVLQLLAEGKNNKEVAAILNLSLYTVETHRGNILQKLNLHSGAELILYAIRKGVIS

Specific function: Probable member of the two-component regulatory system yxjM/yxjL [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=213, Percent_Identity=33.8028169014084, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI1788521, Length=211, Percent_Identity=36.0189573459716, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=36.1386138613861, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786747, Length=209, Percent_Identity=30.622009569378, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787473, Length=186, Percent_Identity=36.0215053763441, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788712, Length=208, Percent_Identity=25.4807692307692, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788546, Length=211, Percent_Identity=27.0142180094787, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23739; Mature: 23739

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIRILLADDHTVVRKGLRLLLESHPGFQVIGDAADGRDAVSLAGEHTPDVVVMDVAMP
CCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHCCCCCCCCEEEEEECCC
GLNGIEAARQISAKLPHTAIVFLSMHSDESYVLKALKAGARAYLLKDSAEHDLIAAVIAV
CCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCEEEECCCCCHHHHHHEEEC
SEGKAFFSPAISKMLVEDYMRQMQERQIEDSYELLTTREREVLQLLAEGKNNKEVAAILN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
LSLYTVETHRGNILQKLNLHSGAELILYAIRKGVIS
EEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTIRILLADDHTVVRKGLRLLLESHPGFQVIGDAADGRDAVSLAGEHTPDVVVMDVAMP
CCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHCCCCCCCCEEEEEECCC
GLNGIEAARQISAKLPHTAIVFLSMHSDESYVLKALKAGARAYLLKDSAEHDLIAAVIAV
CCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCEEEECCCCCHHHHHHEEEC
SEGKAFFSPAISKMLVEDYMRQMQERQIEDSYELLTTREREVLQLLAEGKNNKEVAAILN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
LSLYTVETHRGNILQKLNLHSGAELILYAIRKGVIS
EEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]