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The map label for this gene is dapA [H]

Identifier: 116620194

GI number: 116620194

Start: 1319685

End: 1320578

Strand: Reverse

Name: dapA [H]

Synonym: Acid_1067

Alternate gene names: 116620194

Gene position: 1320578-1319685 (Counterclockwise)

Preceding gene: 116620197

Following gene: 116620186

Centisome position: 13.25

GC content: 61.07

Gene sequence:

>894_bases
ATGGCACCGATGAAGCTACAAGGTATTTTCCCACCAATCACAACCCCATTCGATCACAAAGGCGACATTTATCTTTCCAA
GATTCAACACAATGTCGAGAAGTGGAACCTGACCACGCTTTCCGGCTACGTAGTCATGGGTTCCACCGGCGAGAGCGTCA
TGGTCACCCCGGAGGAGAAGTATACGGTTTGGGAACTCGTGGCCAAACACGCCGCCGCCGAAAAGCTCCTGATCGCCGGC
ACCGGCGTGGAAAGCGTCCGCGAGACGGTAGACCTCACGAATCGCGCCGCCGCCATAGGCTACAGGGCAGCGATGGTGCG
CACGCCGCACTATTACAAAAATCTGATCAACCGCACCGACGCGCAGATTCTCTACTTCCGCGCCGTAGCCGACCGGGCGA
AGATTCCTCTGATCATCTATAACTGGCCGCAGACCACCGGCATCGACATCTCGGTGGAAGCCGTGAACGCATTGAGCGGG
CATCCGAATATCATCGCCATCAAGGAGAGCTCGGGCAACCTGGAAAAGGTGATGCAGATGATCCGCGAGGTGGAACCCGG
CTTCCAGGTCCTGGTGGGCTCCGCGCCCACGCTGTGGCCTTCGCTGTTGATGGGCGCCTGCGGAGCCATCCTCGCCTACG
CCAATGCCGCGCCGTATTCCGTCATCGCCATCTGGGAAGCCTACCGCACCCGCGAAGAAGCTGCCGGCCTGGACTGGCAA
AGCCGCATCGCCCGCGCCGCCGCCCTGGTCACCACGAAGTACGGTATCCCCGGCCTCAAGCACGCCATGGACTTGAACGG
CTACTACGGCGGCCCCCCTCGCCTCCCGCTCACCGTCCCCTCACCCGCCGCCAAACAGGAGATCGAACAGGCCTTCCGCG
ACCTGAAAGGCTAA

Upstream 100 bases:

>100_bases
CCACAACTCGGCGATCAGCATATCGCGATCATCCGGGTCGCAATCGATTTCGAGCGAAAACATGATTCCCATCCCCGTCA
GGTACAGGTGCTATTTTGGA

Downstream 100 bases:

>100_bases
GGCAATTTTCTTATGCGCGGATAAAAAGTCCTCTCTTTAATTCCCCCCGCCGAGCAGGTTCTCGATCAACGCACGCTGCA
TGGGCCAGTAGCCCTGCACG

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MAPMKLQGIFPPITTPFDHKGDIYLSKIQHNVEKWNLTTLSGYVVMGSTGESVMVTPEEKYTVWELVAKHAAAEKLLIAG
TGVESVRETVDLTNRAAAIGYRAAMVRTPHYYKNLINRTDAQILYFRAVADRAKIPLIIYNWPQTTGIDISVEAVNALSG
HPNIIAIKESSGNLEKVMQMIREVEPGFQVLVGSAPTLWPSLLMGACGAILAYANAAPYSVIAIWEAYRTREEAAGLDWQ
SRIARAAALVTTKYGIPGLKHAMDLNGYYGGPPRLPLTVPSPAAKQEIEQAFRDLKG

Sequences:

>Translated_297_residues
MAPMKLQGIFPPITTPFDHKGDIYLSKIQHNVEKWNLTTLSGYVVMGSTGESVMVTPEEKYTVWELVAKHAAAEKLLIAG
TGVESVRETVDLTNRAAAIGYRAAMVRTPHYYKNLINRTDAQILYFRAVADRAKIPLIIYNWPQTTGIDISVEAVNALSG
HPNIIAIKESSGNLEKVMQMIREVEPGFQVLVGSAPTLWPSLLMGACGAILAYANAAPYSVIAIWEAYRTREEAAGLDWQ
SRIARAAALVTTKYGIPGLKHAMDLNGYYGGPPRLPLTVPSPAAKQEIEQAFRDLKG
>Mature_296_residues
APMKLQGIFPPITTPFDHKGDIYLSKIQHNVEKWNLTTLSGYVVMGSTGESVMVTPEEKYTVWELVAKHAAAEKLLIAGT
GVESVRETVDLTNRAAAIGYRAAMVRTPHYYKNLINRTDAQILYFRAVADRAKIPLIIYNWPQTTGIDISVEAVNALSGH
PNIIAIKESSGNLEKVMQMIREVEPGFQVLVGSAPTLWPSLLMGACGAILAYANAAPYSVIAIWEAYRTREEAAGLDWQS
RIARAAALVTTKYGIPGLKHAMDLNGYYGGPPRLPLTVPSPAAKQEIEQAFRDLKG

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=290, Percent_Identity=37.5862068965517, Blast_Score=195, Evalue=4e-50,
Organism=Homo sapiens, GI13540533, Length=299, Percent_Identity=28.0936454849498, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1786463, Length=235, Percent_Identity=30.2127659574468, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788823, Length=212, Percent_Identity=32.5471698113208, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI87082415, Length=249, Percent_Identity=26.5060240963855, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789620, Length=265, Percent_Identity=27.9245283018868, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32524; Mature: 32393

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPMKLQGIFPPITTPFDHKGDIYLSKIQHNVEKWNLTTLSGYVVMGSTGESVMVTPEEK
CCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHEEEEEEEEEEEECCCCCEEEECCCCC
YTVWELVAKHAAAEKLLIAGTGVESVRETVDLTNRAAAIGYRAAMVRTPHYYKNLINRTD
HHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHCCCC
AQILYFRAVADRAKIPLIIYNWPQTTGIDISVEAVNALSGHPNIIAIKESSGNLEKVMQM
CCEEEEEEHHCCCCCCEEEEECCCCCCCEEEEEEEHHCCCCCCEEEEECCCCCHHHHHHH
IREVEPGFQVLVGSAPTLWPSLLMGACGAILAYANAAPYSVIAIWEAYRTREEAAGLDWQ
HHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCHH
SRIARAAALVTTKYGIPGLKHAMDLNGYYGGPPRLPLTVPSPAAKQEIEQAFRDLKG
HHHHHHHHHHHHCCCCCCHHHHEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
APMKLQGIFPPITTPFDHKGDIYLSKIQHNVEKWNLTTLSGYVVMGSTGESVMVTPEEK
CCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHEEEEEEEEEEEECCCCCEEEECCCCC
YTVWELVAKHAAAEKLLIAGTGVESVRETVDLTNRAAAIGYRAAMVRTPHYYKNLINRTD
HHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHCCCC
AQILYFRAVADRAKIPLIIYNWPQTTGIDISVEAVNALSGHPNIIAIKESSGNLEKVMQM
CCEEEEEEHHCCCCCCEEEEECCCCCCCEEEEEEEHHCCCCCCEEEEECCCCCHHHHHHH
IREVEPGFQVLVGSAPTLWPSLLMGACGAILAYANAAPYSVIAIWEAYRTREEAAGLDWQ
HHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCHH
SRIARAAALVTTKYGIPGLKHAMDLNGYYGGPPRLPLTVPSPAAKQEIEQAFRDLKG
HHHHHHHHHHHHCCCCCCHHHHEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA