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The map label for this gene is lolC [H]

Identifier: 116620160

GI number: 116620160

Start: 1278356

End: 1279582

Strand: Reverse

Name: lolC [H]

Synonym: Acid_1033

Alternate gene names: 116620160

Gene position: 1279582-1278356 (Counterclockwise)

Preceding gene: 116620161

Following gene: 116620157

Centisome position: 12.84

GC content: 61.53

Gene sequence:

>1227_bases
GTGAAGACCTTCGAGCTGTTCATCGCCGGCCGGTATCTGCGAGCGCGCCGCAAGGAGGCGGTGATCTCTGTGATCACGGC
GATCTCGGTGCTCGGCGTGGCGGCGGGCGTGATGGCGCTGGTGATCGCACTGGCGGTGACCAGCGGGTTTAGCAAGACGT
TGCAGCACAACTTGCTGGGAGCGATGGCGCACATCAGCGTGATTCCGCGCCAACCCGGGGACGGGATCGAGAACTGGCAG
GAGCTGGTGGTGGGGATCCGCAAGGTGCCGCACGTGACCGCGGTATCGCCGGCCTTGTACAGTCCCACATTTCTGACGGG
GCCGATTCAATCCAAGGGCGCCTACATCAAGGGCGTGGATTTGGATTCGGAACTGGCGCTGAGCGGCACGCTGCGCAAAC
TGAAGTCGGGGTCGCTGGACCGGCTGCGCGACCCGAACGCCTCGCCGCCGGGAATCATCCTGGGATCGCGGCTGGCGGAG
GATGTCGGCATGCGAGTGGGCGACAATGTCGAACTGCTGGCGGACGAGATGTTGCCGGTCGGAGTAAGGCCGGTGAAGCG
GCGCTTTAAAGTGGCCGGCCTCTTTGAGACAGGATTCTACGAGATCGACGACTTGTGGGCGTACATGTCGATCGGGGCCG
CGCAGAAGGCGTTCTCGACGGATCAGATCAACCAAATCGAAATCAATGTGGACGATCTCAACCTGGCGGGACGGGTGGCG
CCTGAGATCGAGAAGGTGGCGGGGCCGCGTTATACGACGACGACCTGGATGGAGCGGAATAAGCAGATTCTGGGAGCGCT
GCGCATGGAGCGGCTGGTGACGATCATCGTGATCAGCCTGATTGAGCTGGTGGCGGCGCTGAATATTTTCATCACGCTGG
TAATGATGGTGATGGAGAAGTATCGCGACATCGCGGTTCTGATGTCAATGGGCGCGCGGGTCGGGCAGATCCGGCGGATC
TTCATGCTGCAGGGAGTGCTGATCGGCGTGGTGGGAAGTGCGATCGGGCTGGCGGCGGGGTATGCGCTGTGCTACTTCGC
CGGGCACTACCGGTGGATTCCGTTGGATGAAGCGGTATATTCAATGAGCTTTGTGCCGTTCGACCCGCAGTGGACGGATG
CGTTCTGGATCGCGGGGCTGGCAATTCTGGTGAGTTTTTTGGCGACGCTGTATCCGGCGTGGAATGCGACCAAAATCGCG
CCGGCGGAAGTGCTGAGGTACGAGTAA

Upstream 100 bases:

>100_bases
TGACCGGATCGCGCTCCATCCGCGACGTGATTCTGTTCCCGCTGCTGCGGCCGGAAGGGCCGATCGAACTGGTGGGGCAA
CTGCGCGAATCCGACAAACT

Downstream 100 bases:

>100_bases
AGAACGAGCCGCGACCGTGAGGGAGCGCTTCCGGGTAGCGCTCCCTCACGGTCGCGGCTCGTTGTGAGTTAGTTGCCGCC
TTCTTCGGAGAGGGTGAAGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKTFELFIAGRYLRARRKEAVISVITAISVLGVAAGVMALVIALAVTSGFSKTLQHNLLGAMAHISVIPRQPGDGIENWQ
ELVVGIRKVPHVTAVSPALYSPTFLTGPIQSKGAYIKGVDLDSELALSGTLRKLKSGSLDRLRDPNASPPGIILGSRLAE
DVGMRVGDNVELLADEMLPVGVRPVKRRFKVAGLFETGFYEIDDLWAYMSIGAAQKAFSTDQINQIEINVDDLNLAGRVA
PEIEKVAGPRYTTTTWMERNKQILGALRMERLVTIIVISLIELVAALNIFITLVMMVMEKYRDIAVLMSMGARVGQIRRI
FMLQGVLIGVVGSAIGLAAGYALCYFAGHYRWIPLDEAVYSMSFVPFDPQWTDAFWIAGLAILVSFLATLYPAWNATKIA
PAEVLRYE

Sequences:

>Translated_408_residues
MKTFELFIAGRYLRARRKEAVISVITAISVLGVAAGVMALVIALAVTSGFSKTLQHNLLGAMAHISVIPRQPGDGIENWQ
ELVVGIRKVPHVTAVSPALYSPTFLTGPIQSKGAYIKGVDLDSELALSGTLRKLKSGSLDRLRDPNASPPGIILGSRLAE
DVGMRVGDNVELLADEMLPVGVRPVKRRFKVAGLFETGFYEIDDLWAYMSIGAAQKAFSTDQINQIEINVDDLNLAGRVA
PEIEKVAGPRYTTTTWMERNKQILGALRMERLVTIIVISLIELVAALNIFITLVMMVMEKYRDIAVLMSMGARVGQIRRI
FMLQGVLIGVVGSAIGLAAGYALCYFAGHYRWIPLDEAVYSMSFVPFDPQWTDAFWIAGLAILVSFLATLYPAWNATKIA
PAEVLRYE
>Mature_408_residues
MKTFELFIAGRYLRARRKEAVISVITAISVLGVAAGVMALVIALAVTSGFSKTLQHNLLGAMAHISVIPRQPGDGIENWQ
ELVVGIRKVPHVTAVSPALYSPTFLTGPIQSKGAYIKGVDLDSELALSGTLRKLKSGSLDRLRDPNASPPGIILGSRLAE
DVGMRVGDNVELLADEMLPVGVRPVKRRFKVAGLFETGFYEIDDLWAYMSIGAAQKAFSTDQINQIEINVDDLNLAGRVA
PEIEKVAGPRYTTTTWMERNKQILGALRMERLVTIIVISLIELVAALNIFITLVMMVMEKYRDIAVLMSMGARVGQIRRI
FMLQGVLIGVVGSAIGLAAGYALCYFAGHYRWIPLDEAVYSMSFVPFDPQWTDAFWIAGLAILVSFLATLYPAWNATKIA
PAEVLRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=414, Percent_Identity=28.9855072463768, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1787360, Length=415, Percent_Identity=28.6746987951807, Blast_Score=132, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44673; Mature: 44673

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFELFIAGRYLRARRKEAVISVITAISVLGVAAGVMALVIALAVTSGFSKTLQHNLLG
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMAHISVIPRQPGDGIENWQELVVGIRKVPHVTAVSPALYSPTFLTGPIQSKGAYIKGVD
HHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCCEEECCCCCCCCEEEECC
LDSELALSGTLRKLKSGSLDRLRDPNASPPGIILGSRLAEDVGMRVGDNVELLADEMLPV
CCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEHHHHHHHHCCCCCCCHHHHHHHHCCC
GVRPVKRRFKVAGLFETGFYEIDDLWAYMSIGAAQKAFSTDQINQIEINVDDLNLAGRVA
CCHHHHHHHHHHEEHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
PEIEKVAGPRYTTTTWMERNKQILGALRMERLVTIIVISLIELVAALNIFITLVMMVMEK
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRDIAVLMSMGARVGQIRRIFMLQGVLIGVVGSAIGLAAGYALCYFAGHYRWIPLDEAVY
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHH
SMSFVPFDPQWTDAFWIAGLAILVSFLATLYPAWNATKIAPAEVLRYE
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MKTFELFIAGRYLRARRKEAVISVITAISVLGVAAGVMALVIALAVTSGFSKTLQHNLLG
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMAHISVIPRQPGDGIENWQELVVGIRKVPHVTAVSPALYSPTFLTGPIQSKGAYIKGVD
HHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCCEEECCCCCCCCEEEECC
LDSELALSGTLRKLKSGSLDRLRDPNASPPGIILGSRLAEDVGMRVGDNVELLADEMLPV
CCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEHHHHHHHHCCCCCCCHHHHHHHHCCC
GVRPVKRRFKVAGLFETGFYEIDDLWAYMSIGAAQKAFSTDQINQIEINVDDLNLAGRVA
CCHHHHHHHHHHEEHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
PEIEKVAGPRYTTTTWMERNKQILGALRMERLVTIIVISLIELVAALNIFITLVMMVMEK
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRDIAVLMSMGARVGQIRRIFMLQGVLIGVVGSAIGLAAGYALCYFAGHYRWIPLDEAVY
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHH
SMSFVPFDPQWTDAFWIAGLAILVSFLATLYPAWNATKIAPAEVLRYE
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]