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The map label for this gene is ruvB

Identifier: 116620085

GI number: 116620085

Start: 1195296

End: 1196330

Strand: Direct

Name: ruvB

Synonym: Acid_0957

Alternate gene names: 116620085

Gene position: 1195296-1196330 (Clockwise)

Preceding gene: 116620084

Following gene: 116620086

Centisome position: 11.99

GC content: 64.25

Gene sequence:

>1035_bases
ATGCCCGACCGGGAACTGATCTCCGGTGATCGGCAGGCCGAAGATGCGCAGTTCGAAGTGGGCCTTCGCCCGCGCCGTTT
GGCCGATTTCACCGGACAGAGCAAGCTGAAGGAAAATCTATCGATCGCCATCGAAGCCGCCCGCATGCGCGGCGAGGCGA
TGGACCACGTGCTCCTCTATGGTCCGCCGGGCCTGGGCAAGACCACGCTCGCCTCCATCATCGCCGAGGAGTTGCAGGTG
CAGTTCACGCCCACCTCCGGCCCGGTGCTGCAGAAGAAGCTCGATCTCACCGGCATCCTCAGCAATATTCGTCTTCACCA
GGTCTTCTTCATCGACGAGATTCACCGGCTGCTGCCCGACGTGGAGGAGATGCTGTACTCCGCGCTGGAGGATTTCCGCG
TCGATATCCTGGTGGGCGTCGGCCCCGGCGCGCGCACTCATTCGCTACCCATGCCGAAGTTCACCGCCATCGGGGCGACT
ACACGCCAGGGCCTGGTGAGTGCTCCGCTGCGCGGCCGCTTCGGCCTGGTGCTGCGGCTCGACCCCTACAACACCGAAGA
GCTCAAGGCGATTGTGAAGCGCTCCGCGCGCCTGCTCACGGTGGAGATCGAGGATGGCGCCGCCGAAGAGATCGCGCGCC
GCTGCCGCGGGACGCCGCGTATCGCCAACCGCCTGCTGCGCCGGGTGCGCGACTATGCGCAGGTCCGCGCCGATGGCCGC
ATCAACCAGAAGGTCGCGCAGACCGCGCTCAACCTGCTCGACGTCGATCGCTACGGTCTCGATGAGATCGATCAGAAGAT
CATGATGACGATCCTTGAGAAATACCGGGGCGGACCGGTCGGGGTGAACACGATCGCGGCTTCCATTTCCGAGGAGTCGG
AGACCATCGAGGAGGTCTATGAGCCCTACCTCATTCAGCTCGGCTTCCTTAACCGCACGCCGCGCGGCCGCGTCGCTACG
GAACTGGCCTACGACTACTTCAAGGTGAAGCGCAAGCTGCGCGAAGGCGATCACCCGAGCCTGTTCGAGGCATGA

Upstream 100 bases:

>100_bases
CGAGGCGGCGGTGCGCAAGGCCAAGGCCGCCGGCGCTTCGCTCGACTTCGAGCCGCTCTTCCGCCGCGCTTTGGAACTGG
TACGGTAAGCTGGTAATCAC

Downstream 100 bases:

>100_bases
AGCCGGTCTATCTTTCGCTCGGGTCCAACATCGGCGACCGCCACGCCAATCTGCGCGCCGCGATCGAGGCGCTCGATGCC
GGCGGGGTACGTGTGCTTCG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MPDRELISGDRQAEDAQFEVGLRPRRLADFTGQSKLKENLSIAIEAARMRGEAMDHVLLYGPPGLGKTTLASIIAEELQV
QFTPTSGPVLQKKLDLTGILSNIRLHQVFFIDEIHRLLPDVEEMLYSALEDFRVDILVGVGPGARTHSLPMPKFTAIGAT
TRQGLVSAPLRGRFGLVLRLDPYNTEELKAIVKRSARLLTVEIEDGAAEEIARRCRGTPRIANRLLRRVRDYAQVRADGR
INQKVAQTALNLLDVDRYGLDEIDQKIMMTILEKYRGGPVGVNTIAASISEESETIEEVYEPYLIQLGFLNRTPRGRVAT
ELAYDYFKVKRKLREGDHPSLFEA

Sequences:

>Translated_344_residues
MPDRELISGDRQAEDAQFEVGLRPRRLADFTGQSKLKENLSIAIEAARMRGEAMDHVLLYGPPGLGKTTLASIIAEELQV
QFTPTSGPVLQKKLDLTGILSNIRLHQVFFIDEIHRLLPDVEEMLYSALEDFRVDILVGVGPGARTHSLPMPKFTAIGAT
TRQGLVSAPLRGRFGLVLRLDPYNTEELKAIVKRSARLLTVEIEDGAAEEIARRCRGTPRIANRLLRRVRDYAQVRADGR
INQKVAQTALNLLDVDRYGLDEIDQKIMMTILEKYRGGPVGVNTIAASISEESETIEEVYEPYLIQLGFLNRTPRGRVAT
ELAYDYFKVKRKLREGDHPSLFEA
>Mature_343_residues
PDRELISGDRQAEDAQFEVGLRPRRLADFTGQSKLKENLSIAIEAARMRGEAMDHVLLYGPPGLGKTTLASIIAEELQVQ
FTPTSGPVLQKKLDLTGILSNIRLHQVFFIDEIHRLLPDVEEMLYSALEDFRVDILVGVGPGARTHSLPMPKFTAIGATT
RQGLVSAPLRGRFGLVLRLDPYNTEELKAIVKRSARLLTVEIEDGAAEEIARRCRGTPRIANRLLRRVRDYAQVRADGRI
NQKVAQTALNLLDVDRYGLDEIDQKIMMTILEKYRGGPVGVNTIAASISEESETIEEVYEPYLIQLGFLNRTPRGRVATE
LAYDYFKVKRKLREGDHPSLFEA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=327, Percent_Identity=52.5993883792049, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_SOLUE (Q02AG6)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_822241.1
- ProteinModelPortal:   Q02AG6
- SMR:   Q02AG6
- STRING:   Q02AG6
- GeneID:   4430904
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_0957
- NMPDR:   fig|234267.9.peg.899
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 38578; Mature: 38447

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDRELISGDRQAEDAQFEVGLRPRRLADFTGQSKLKENLSIAIEAARMRGEAMDHVLLY
CCCCHHHCCCCCCCCCEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEE
GPPGLGKTTLASIIAEELQVQFTPTSGPVLQKKLDLTGILSNIRLHQVFFIDEIHRLLPD
CCCCCCHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEEMLYSALEDFRVDILVGVGPGARTHSLPMPKFTAIGATTRQGLVSAPLRGRFGLVLRL
HHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCEEECCCHHHCCHHCCCCCCCEEEEEEE
DPYNTEELKAIVKRSARLLTVEIEDGAAEEIARRCRGTPRIANRLLRRVRDYAQVRADGR
CCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
INQKVAQTALNLLDVDRYGLDEIDQKIMMTILEKYRGGPVGVNTIAASISEESETIEEVY
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
EPYLIQLGFLNRTPRGRVATELAYDYFKVKRKLREGDHPSLFEA
HHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PDRELISGDRQAEDAQFEVGLRPRRLADFTGQSKLKENLSIAIEAARMRGEAMDHVLLY
CCCHHHCCCCCCCCCEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEE
GPPGLGKTTLASIIAEELQVQFTPTSGPVLQKKLDLTGILSNIRLHQVFFIDEIHRLLPD
CCCCCCHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEEMLYSALEDFRVDILVGVGPGARTHSLPMPKFTAIGATTRQGLVSAPLRGRFGLVLRL
HHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCEEECCCHHHCCHHCCCCCCCEEEEEEE
DPYNTEELKAIVKRSARLLTVEIEDGAAEEIARRCRGTPRIANRLLRRVRDYAQVRADGR
CCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
INQKVAQTALNLLDVDRYGLDEIDQKIMMTILEKYRGGPVGVNTIAASISEESETIEEVY
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
EPYLIQLGFLNRTPRGRVATELAYDYFKVKRKLREGDHPSLFEA
HHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA