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The map label for this gene is ruvA

Identifier: 116620084

GI number: 116620084

Start: 1194690

End: 1195283

Strand: Direct

Name: ruvA

Synonym: Acid_0956

Alternate gene names: 116620084

Gene position: 1194690-1195283 (Clockwise)

Preceding gene: 116620079

Following gene: 116620085

Centisome position: 11.99

GC content: 65.82

Gene sequence:

>594_bases
ATGATCGCCTTACTGCGCGGGTTAGTCGTGGAGAAACATCCGAACCAGGTGCTGGTAGAGACCGGCGGCGTGGGGTACGA
CGTCACCATCCCGGTCTCCACCTTCACCAAACTGCCCGACCTGGGCGGCGAAGTCCGTCTCCGCATCTACACCCACGTGC
GCGAAGACGTGCTCGCCCTCTATGGTTTCCTCACCCAGGACGAAAAGGCGCTTTTCGAGAAGCTGATCTCGGTGAGCGGC
ATCGGTCCCACGCTCGCGGTCAAGATCCTCTCCGGCCTCGCTGCCGCGGACCTCATCCTCTCGATCCGCCGCGGCGAGGT
CGAGAAGCTGGTGAAGGTCCCGGGTGTCGGCAAGAAGACTGCCGAGCGTATGGTGCTCGAACTCCGCGACAAACTTCCCG
CCGCGACCGGCGAAGAGCCCGGCGCACCTGCGGCCGAAGCGCTGTCGCCGATCGATCAGGACGTGCTCTCCGCCCTGCTC
AACCTGGGCTGCGCACGCCCACAGGCCGAGGCGGCGGTGCGCAAGGCCAAGGCCGCCGGCGCTTCGCTCGACTTCGAGCC
GCTCTTCCGCCGCGCTTTGGAACTGGTACGGTAA

Upstream 100 bases:

>100_bases
CGCGCAGTTCGGCCGCACCATTGCGGATTGCGTCTACGAAAAACCTACGTCGGGCCACGGCACTTATTGTAGCGACTCCA
AGTGGCTACAATCATTACTG

Downstream 100 bases:

>100_bases
GCTGGTAATCACATGCCCGACCGGGAACTGATCTCCGGTGATCGGCAGGCCGAAGATGCGCAGTTCGAAGTGGGCCTTCG
CCCGCGCCGTTTGGCCGATT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MIALLRGLVVEKHPNQVLVETGGVGYDVTIPVSTFTKLPDLGGEVRLRIYTHVREDVLALYGFLTQDEKALFEKLISVSG
IGPTLAVKILSGLAAADLILSIRRGEVEKLVKVPGVGKKTAERMVLELRDKLPAATGEEPGAPAAEALSPIDQDVLSALL
NLGCARPQAEAAVRKAKAAGASLDFEPLFRRALELVR

Sequences:

>Translated_197_residues
MIALLRGLVVEKHPNQVLVETGGVGYDVTIPVSTFTKLPDLGGEVRLRIYTHVREDVLALYGFLTQDEKALFEKLISVSG
IGPTLAVKILSGLAAADLILSIRRGEVEKLVKVPGVGKKTAERMVLELRDKLPAATGEEPGAPAAEALSPIDQDVLSALL
NLGCARPQAEAAVRKAKAAGASLDFEPLFRRALELVR
>Mature_197_residues
MIALLRGLVVEKHPNQVLVETGGVGYDVTIPVSTFTKLPDLGGEVRLRIYTHVREDVLALYGFLTQDEKALFEKLISVSG
IGPTLAVKILSGLAAADLILSIRRGEVEKLVKVPGVGKKTAERMVLELRDKLPAATGEEPGAPAAEALSPIDQDVLSALL
NLGCARPQAEAAVRKAKAAGASLDFEPLFRRALELVR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=42.2885572139304, Blast_Score=149, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_SOLUE (Q02AG7)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_822240.1
- ProteinModelPortal:   Q02AG7
- SMR:   Q02AG7
- STRING:   Q02AG7
- GeneID:   4430903
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_0956
- NMPDR:   fig|234267.9.peg.898
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- PhylomeDB:   Q02AG7
- ProtClustDB:   PRK00116
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21041; Mature: 21041

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALLRGLVVEKHPNQVLVETGGVGYDVTIPVSTFTKLPDLGGEVRLRIYTHVREDVLAL
CHHHHHHHHHCCCCCEEEEECCCCCEEEEECHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
YGFLTQDEKALFEKLISVSGIGPTLAVKILSGLAAADLILSIRRGEVEKLVKVPGVGKKT
HHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AERMVLELRDKLPAATGEEPGAPAAEALSPIDQDVLSALLNLGCARPQAEAAVRKAKAAG
HHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCC
ASLDFEPLFRRALELVR
CCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MIALLRGLVVEKHPNQVLVETGGVGYDVTIPVSTFTKLPDLGGEVRLRIYTHVREDVLAL
CHHHHHHHHHCCCCCEEEEECCCCCEEEEECHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
YGFLTQDEKALFEKLISVSGIGPTLAVKILSGLAAADLILSIRRGEVEKLVKVPGVGKKT
HHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AERMVLELRDKLPAATGEEPGAPAAEALSPIDQDVLSALLNLGCARPQAEAAVRKAKAAG
HHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCC
ASLDFEPLFRRALELVR
CCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA