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The map label for this gene is pfpI [H]

Identifier: 116620003

GI number: 116620003

Start: 1093108

End: 1093821

Strand: Direct

Name: pfpI [H]

Synonym: Acid_0875

Alternate gene names: 116620003

Gene position: 1093108-1093821 (Clockwise)

Preceding gene: 116620002

Following gene: 116620006

Centisome position: 10.97

GC content: 63.03

Gene sequence:

>714_bases
ATGGATCAGAGACTGAAAGGCCGCCGAATCGCGGCTCTCGCGGCGGACGGCTTCGAAAAGGTGGAGCTGGTCATCCCGAT
GAAGGCATTACAGGCGGCCGGCGCTAAAGTTGACGTGATCTCGCTGCGCCACGGTAATATCCGCGGCGTGAACTTGCACG
AGCCGGCCAGCCGCGTACACGTGAACAAAACGATTGCCGAAGCGAACCCCGACGACTACGACGGGCTGCTGCTTCCGGGG
GGCTTTATCAACCCCGACCTGCTCCGCCAATCGGCGGAGGCGCGGGAATTCGTGCGTGCGTTTGACCGGGCGGGCAAGCC
GATCGCGAGTCTGTGTCATGGACCCTGGGTGCTCGCGTCGGCGGGATTGTTACAGGGCAGAACCTTAACGTCCTGGCCGG
GCGTCCGTGACGATCTAGTCAATGCCGGCGCGACCTGGCTGGATCAGGAGTTCGTTCGCGACGGCAATCTGGCGACGAGC
CGCGGCCCCCAGGACCTCATCCCGTTCGTCAAAGGCTGTCTGGACCTTTTTGCGCAAGACGCTCCGCTTTCGAAAAAAGA
GCAACAACCCATTTCCCGCTCGGCGCCCCAGGCGAATGAGCCGCCAGAGATAGTTGTGGGCGCCATGAAATGGCTCCCAA
AACCGTCCTTGCGAACGGCGGTCGGGCTGGGTGCGATCGCCGCGGTCTTCCTGGCGGCATGGTCACGTCGCTGA

Upstream 100 bases:

>100_bases
TACTGTCCGGAGCTCGTTGCCGCTCGACCACCGTTCGAGCGTCGCCTCCACGACATTTAAGAAAGTTCCAGGACGTGTTT
GCGAAGGAAAGGAGACATCA

Downstream 100 bases:

>100_bases
AACGACGAAGTCACACCACGGGGGCCGCGATGAGTGGAAACACATCAGGCGGCTTACCCCTTCCGTCCTGTTTCACGCGG
CTGAACAACACGGCGCTATT

Product: PfpI family intracellular peptidase

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MDQRLKGRRIAALAADGFEKVELVIPMKALQAAGAKVDVISLRHGNIRGVNLHEPASRVHVNKTIAEANPDDYDGLLLPG
GFINPDLLRQSAEAREFVRAFDRAGKPIASLCHGPWVLASAGLLQGRTLTSWPGVRDDLVNAGATWLDQEFVRDGNLATS
RGPQDLIPFVKGCLDLFAQDAPLSKKEQQPISRSAPQANEPPEIVVGAMKWLPKPSLRTAVGLGAIAAVFLAAWSRR

Sequences:

>Translated_237_residues
MDQRLKGRRIAALAADGFEKVELVIPMKALQAAGAKVDVISLRHGNIRGVNLHEPASRVHVNKTIAEANPDDYDGLLLPG
GFINPDLLRQSAEAREFVRAFDRAGKPIASLCHGPWVLASAGLLQGRTLTSWPGVRDDLVNAGATWLDQEFVRDGNLATS
RGPQDLIPFVKGCLDLFAQDAPLSKKEQQPISRSAPQANEPPEIVVGAMKWLPKPSLRTAVGLGAIAAVFLAAWSRR
>Mature_237_residues
MDQRLKGRRIAALAADGFEKVELVIPMKALQAAGAKVDVISLRHGNIRGVNLHEPASRVHVNKTIAEANPDDYDGLLLPG
GFINPDLLRQSAEAREFVRAFDRAGKPIASLCHGPWVLASAGLLQGRTLTSWPGVRDDLVNAGATWLDQEFVRDGNLATS
RGPQDLIPFVKGCLDLFAQDAPLSKKEQQPISRSAPQANEPPEIVVGAMKWLPKPSLRTAVGLGAIAAVFLAAWSRR

Specific function: Unknown

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=170, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI31543380, Length=170, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI87082219, Length=171, Percent_Identity=39.1812865497076, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87081736, Length=172, Percent_Identity=31.3953488372093, Blast_Score=61, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28571932, Length=155, Percent_Identity=33.5483870967742, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 25575; Mature: 25575

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQRLKGRRIAALAADGFEKVELVIPMKALQAAGAKVDVISLRHGNIRGVNLHEPASRVH
CCCCCCCCEEEEEECCCCCEEEEEECHHHHHHCCCEEEEEEECCCCEECCCCCCCHHHHH
VNKTIAEANPDDYDGLLLPGGFINPDLLRQSAEAREFVRAFDRAGKPIASLCHGPWVLAS
HHHHHHCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHH
AGLLQGRTLTSWPGVRDDLVNAGATWLDQEFVRDGNLATSRGPQDLIPFVKGCLDLFAQD
HHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
APLSKKEQQPISRSAPQANEPPEIVVGAMKWLPKPSLRTAVGLGAIAAVFLAAWSRR
CCCCCHHCCCCHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDQRLKGRRIAALAADGFEKVELVIPMKALQAAGAKVDVISLRHGNIRGVNLHEPASRVH
CCCCCCCCEEEEEECCCCCEEEEEECHHHHHHCCCEEEEEEECCCCEECCCCCCCHHHHH
VNKTIAEANPDDYDGLLLPGGFINPDLLRQSAEAREFVRAFDRAGKPIASLCHGPWVLAS
HHHHHHCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHH
AGLLQGRTLTSWPGVRDDLVNAGATWLDQEFVRDGNLATSRGPQDLIPFVKGCLDLFAQD
HHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
APLSKKEQQPISRSAPQANEPPEIVVGAMKWLPKPSLRTAVGLGAIAAVFLAAWSRR
CCCCCHHCCCCHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]