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The map label for this gene is allB

Identifier: 116619503

GI number: 116619503

Start: 462174

End: 463547

Strand: Direct

Name: allB

Synonym: Acid_0362

Alternate gene names: 116619503

Gene position: 462174-463547 (Clockwise)

Preceding gene: 116619502

Following gene: 116619504

Centisome position: 4.64

GC content: 65.21

Gene sequence:

>1374_bases
ATGAGTGAATGCGTAGTCCGTGGTGGGCAGGTGGTGCAGGCAGGCGGGGTCGTGTCCGCGGACGTGGCGATCGAAGACGG
AAGAATCTCGGCCATTGGGCCCGAGCTTCCCGGCGCGAAGCGCGAGATCAATGCGCGCGGATTGACCGTATTCCCCGGCG
TGATCGACGATCATCTCCACTTCAACGAACCGGGCCGCACCGAGTGGGAAGGCGCGGCAACGGGCAGCAGGGCGCTGGCG
GCGGGTGGCGGTACGGCTTTTTTCGACATGCCGCTCAACTCCACGCCGTGTACGGTGGATCGCGCGGCCTTCGCCGGAAA
GCGCGCGGCGCTGGAGCGCGCGTCGATCGCTGACTTCGCGCTGTGGGGCGGCATCGTGCCGGGCAATCTCAGCGAACTGG
CGCCGCTCGCGGAAAGCGGCGTGATCGGCTTCAAGGCCTTCCTTTCCGACTCGGGCCTGCCCGAATTTCCGCGCGCCGAC
GACCTCACGCTGTACGAAGGCATGCGTGAAGCCGCGCGACTGGGACTGCCGGTCGCTGTGCACGCGGAAAGCGAAGAGAT
CACGTCGCGGCTCACGCGGCGCGCGCGTGACGCCGGACGCACCAGCGCGCGCGACTATCTGGACTCGCGCCCGGTGATCG
CCGAAGTCGAGGCGATCCATCGCGCCGCGCTCCTGGCGCGCGAGGCCGGCTGCAAATTGCACATCGTCCACATCAGCTCC
GGACGCGGTGTGGCTGCGGCTCTCGAAGCGCGCACCATGGGCACCGATATTGCGATCGAAACCTGTGCGCACTATCTCTT
CTTCACGGAGGATGACTTGCTGCGCCTGGGCGCGATAGCCAAGTGCGCGCCGCCGCTGCGCGATCGCCAGGAGTTCGACA
GGTTGTGGGCGCACGTGCTGGGTGGCATCGTGGACGTGGTCGCTTCCGATCATTCGCCCGCGCCGCCCGCGATGAAAACC
GGCGACGATTTCTTCGCCATCTGGGGCGGCATCGCCGGCGTGCAATCCACGCTCGCCGTGCTGCTCGAGGCCGGCCACTT
TCAACGCGGCCTCAGGTTGGAGCGAATCGCGGAGCTCACTGCCGGATATCCGGCGCGACGATTTGCTCTGCACAACAAAG
GCAGCATCGCGGTTGGCAACGACGCGGACCTCACGCTGGTGGACATGGATGGCCAAGAAAACCTCGAGCCGGAATCTCTG
TGGCAGAAGCACCCGGTCAACCCATATACCGGAAACAGTTTTCGCGGCTCGATTCGCCGCACGATGCTGCGCGGCACGAC
GATTTTCAATCATGACGAAATTACCGTAAAGTCCGGCGGCCAACTGCTCCGCCCGAAAGCAAACACCTATGCAACGTCTG
GGATTCACCCGTAG

Upstream 100 bases:

>100_bases
GGTCGCTAATTTGCCGTTTAGATTACCGACCACTCCCTGACGGTCGCGACTCCGATGGCGGCACATCGCACGGGGCGCAG
CCGGCGCTACTGGGTGAAGT

Downstream 100 bases:

>100_bases
CGCGCACCGCTCCGACCATTTGCTGCTCACGCCGGACACCTTCGTCCGCGCGCCCCTGCCCGGCATGACTGGCGCCACCG
CCATCGTGCACGCGGCTCCG

Product: allantoinase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MSECVVRGGQVVQAGGVVSADVAIEDGRISAIGPELPGAKREINARGLTVFPGVIDDHLHFNEPGRTEWEGAATGSRALA
AGGGTAFFDMPLNSTPCTVDRAAFAGKRAALERASIADFALWGGIVPGNLSELAPLAESGVIGFKAFLSDSGLPEFPRAD
DLTLYEGMREAARLGLPVAVHAESEEITSRLTRRARDAGRTSARDYLDSRPVIAEVEAIHRAALLAREAGCKLHIVHISS
GRGVAAALEARTMGTDIAIETCAHYLFFTEDDLLRLGAIAKCAPPLRDRQEFDRLWAHVLGGIVDVVASDHSPAPPAMKT
GDDFFAIWGGIAGVQSTLAVLLEAGHFQRGLRLERIAELTAGYPARRFALHNKGSIAVGNDADLTLVDMDGQENLEPESL
WQKHPVNPYTGNSFRGSIRRTMLRGTTIFNHDEITVKSGGQLLRPKANTYATSGIHP

Sequences:

>Translated_457_residues
MSECVVRGGQVVQAGGVVSADVAIEDGRISAIGPELPGAKREINARGLTVFPGVIDDHLHFNEPGRTEWEGAATGSRALA
AGGGTAFFDMPLNSTPCTVDRAAFAGKRAALERASIADFALWGGIVPGNLSELAPLAESGVIGFKAFLSDSGLPEFPRAD
DLTLYEGMREAARLGLPVAVHAESEEITSRLTRRARDAGRTSARDYLDSRPVIAEVEAIHRAALLAREAGCKLHIVHISS
GRGVAAALEARTMGTDIAIETCAHYLFFTEDDLLRLGAIAKCAPPLRDRQEFDRLWAHVLGGIVDVVASDHSPAPPAMKT
GDDFFAIWGGIAGVQSTLAVLLEAGHFQRGLRLERIAELTAGYPARRFALHNKGSIAVGNDADLTLVDMDGQENLEPESL
WQKHPVNPYTGNSFRGSIRRTMLRGTTIFNHDEITVKSGGQLLRPKANTYATSGIHP
>Mature_456_residues
SECVVRGGQVVQAGGVVSADVAIEDGRISAIGPELPGAKREINARGLTVFPGVIDDHLHFNEPGRTEWEGAATGSRALAA
GGGTAFFDMPLNSTPCTVDRAAFAGKRAALERASIADFALWGGIVPGNLSELAPLAESGVIGFKAFLSDSGLPEFPRADD
LTLYEGMREAARLGLPVAVHAESEEITSRLTRRARDAGRTSARDYLDSRPVIAEVEAIHRAALLAREAGCKLHIVHISSG
RGVAAALEARTMGTDIAIETCAHYLFFTEDDLLRLGAIAKCAPPLRDRQEFDRLWAHVLGGIVDVVASDHSPAPPAMKTG
DDFFAIWGGIAGVQSTLAVLLEAGHFQRGLRLERIAELTAGYPARRFALHNKGSIAVGNDADLTLVDMDGQENLEPESLW
QKHPVNPYTGNSFRGSIRRTMLRGTTIFNHDEITVKSGGQLLRPKANTYATSGIHP

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily

Homologues:

Organism=Homo sapiens, GI19923821, Length=445, Percent_Identity=28.314606741573, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI4503377, Length=457, Percent_Identity=26.9146608315098, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI4503375, Length=471, Percent_Identity=26.7515923566879, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI4503379, Length=459, Percent_Identity=25.7080610021786, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI4503051, Length=460, Percent_Identity=26.7391304347826, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI62422571, Length=460, Percent_Identity=26.7391304347826, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI190194363, Length=460, Percent_Identity=25.4347826086956, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI18105007, Length=404, Percent_Identity=26.980198019802, Blast_Score=117, Evalue=3e-26,
Organism=Escherichia coli, GI1786722, Length=444, Percent_Identity=39.6396396396396, Blast_Score=336, Evalue=2e-93,
Organism=Escherichia coli, GI87082175, Length=459, Percent_Identity=32.6797385620915, Blast_Score=186, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17539558, Length=460, Percent_Identity=26.7391304347826, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI193204318, Length=385, Percent_Identity=26.2337662337662, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71989490, Length=471, Percent_Identity=25.9023354564756, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI86575075, Length=449, Percent_Identity=26.0579064587973, Blast_Score=99, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6322218, Length=407, Percent_Identity=34.6437346437346, Blast_Score=238, Evalue=2e-63,
Organism=Drosophila melanogaster, GI18859883, Length=405, Percent_Identity=34.320987654321, Blast_Score=188, Evalue=7e-48,
Organism=Drosophila melanogaster, GI221377917, Length=464, Percent_Identity=28.2327586206897, Blast_Score=145, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24642586, Length=438, Percent_Identity=26.4840182648402, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI17137462, Length=450, Percent_Identity=27.7777777777778, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24644287, Length=308, Percent_Identity=31.4935064935065, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24644289, Length=235, Percent_Identity=32.3404255319149, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALLB_SOLUE (Q02C42)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_821659.1
- ProteinModelPortal:   Q02C42
- SMR:   Q02C42
- STRING:   Q02C42
- GeneID:   4431577
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_0362
- NMPDR:   fig|234267.9.peg.343
- eggNOG:   COG0044
- HOGENOM:   HBG724623
- OMA:   ICHISSP
- PhylomeDB:   Q02C42
- HAMAP:   MF_01645
- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR03178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.5

Molecular weight: Translated: 48808; Mature: 48677

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSECVVRGGQVVQAGGVVSADVAIEDGRISAIGPELPGAKREINARGLTVFPGVIDDHLH
CCCCEECCCCEEEECCEEEEEEEEECCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCC
FNEPGRTEWEGAATGSRALAAGGGTAFFDMPLNSTPCTVDRAAFAGKRAALERASIADFA
CCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LWGGIVPGNLSELAPLAESGVIGFKAFLSDSGLPEFPRADDLTLYEGMREAARLGLPVAV
HHCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEE
HAESEEITSRLTRRARDAGRTSARDYLDSRPVIAEVEAIHRAALLAREAGCKLHIVHISS
ECCHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GRGVAAALEARTMGTDIAIETCAHYLFFTEDDLLRLGAIAKCAPPLRDRQEFDRLWAHVL
CCCEEEEHHHHHCCCHHHHHHHHHHEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
GGIVDVVASDHSPAPPAMKTGDDFFAIWGGIAGVQSTLAVLLEAGHFQRGLRLERIAELT
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AGYPARRFALHNKGSIAVGNDADLTLVDMDGQENLEPESLWQKHPVNPYTGNSFRGSIRR
CCCCHHHEEECCCCCEEECCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHH
TMLRGTTIFNHDEITVKSGGQLLRPKANTYATSGIHP
HHHHCCEEECCCEEEECCCCCEECCCCCCEECCCCCC
>Mature Secondary Structure 
SECVVRGGQVVQAGGVVSADVAIEDGRISAIGPELPGAKREINARGLTVFPGVIDDHLH
CCCEECCCCEEEECCEEEEEEEEECCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCC
FNEPGRTEWEGAATGSRALAAGGGTAFFDMPLNSTPCTVDRAAFAGKRAALERASIADFA
CCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LWGGIVPGNLSELAPLAESGVIGFKAFLSDSGLPEFPRADDLTLYEGMREAARLGLPVAV
HHCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEE
HAESEEITSRLTRRARDAGRTSARDYLDSRPVIAEVEAIHRAALLAREAGCKLHIVHISS
ECCHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GRGVAAALEARTMGTDIAIETCAHYLFFTEDDLLRLGAIAKCAPPLRDRQEFDRLWAHVL
CCCEEEEHHHHHCCCHHHHHHHHHHEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
GGIVDVVASDHSPAPPAMKTGDDFFAIWGGIAGVQSTLAVLLEAGHFQRGLRLERIAELT
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AGYPARRFALHNKGSIAVGNDADLTLVDMDGQENLEPESLWQKHPVNPYTGNSFRGSIRR
CCCCHHHEEECCCCCEEECCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHH
TMLRGTTIFNHDEITVKSGGQLLRPKANTYATSGIHP
HHHHCCEEECCCEEEECCCCCEECCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA