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The map label for this gene is yedX [C]

Identifier: 116619501

GI number: 116619501

Start: 460458

End: 460811

Strand: Direct

Name: yedX [C]

Synonym: Acid_0360

Alternate gene names: 116619501

Gene position: 460458-460811 (Clockwise)

Preceding gene: 116619500

Following gene: 116619502

Centisome position: 4.62

GC content: 61.3

Gene sequence:

>354_bases
GTGGCTCGTCTTTCCACACACGTTCTGGATACGGCGCGCGGCCAGGCCGCTGCCAATATGAGAGTGGAGTTGTATCGCTT
CGAGAGCGGCGAGCGCGTGCACTGCCTCACCATGCGCACCAACGCCGACGGGCGTACCGACAGCCCGCTACTCTCCGGCG
ATCGAATTGCCACTGGCCACTACGAGATCGCGTTCGCGGCCGGCGATTACTTTCGCGCGCTCGGAGTACCCGTCACCGAT
CCGCCCTTTCTCGATGAAATCGTGGTCCGCTTCGGCATCGCCGATTCAACCGCCAACTACCACGTTCCCCTGCTCGTTTC
CCCATACGGCTACAGTACGTACAAAGGAACCTAA

Upstream 100 bases:

>100_bases
CGGACCTGGGATACCATCGTGGAGCAGGGAGACCGGCTCGGCGTCTATACGGACGCGCGTCCTCCGTACGGTTGCCTCGG
GCTGACTCTCAGGAGATAGC

Downstream 100 bases:

>100_bases
TGCCAGCGCGCCGTGTCATCGATCGCTGCCTGCAACTCGCGCAATTCACCGAGGAACCCGGCTACATCACCCGCACCTAT
CTCTCGCCGCCGATGCACGG

Product: transthyretin

Products: NA

Alternate protein names: HIU hydrolase 2; HIUHase 2 [H]

Number of amino acids: Translated: 117; Mature: 116

Protein sequence:

>117_residues
MARLSTHVLDTARGQAAANMRVELYRFESGERVHCLTMRTNADGRTDSPLLSGDRIATGHYEIAFAAGDYFRALGVPVTD
PPFLDEIVVRFGIADSTANYHVPLLVSPYGYSTYKGT

Sequences:

>Translated_117_residues
MARLSTHVLDTARGQAAANMRVELYRFESGERVHCLTMRTNADGRTDSPLLSGDRIATGHYEIAFAAGDYFRALGVPVTD
PPFLDEIVVRFGIADSTANYHVPLLVSPYGYSTYKGT
>Mature_116_residues
ARLSTHVLDTARGQAAANMRVELYRFESGERVHCLTMRTNADGRTDSPLLSGDRIATGHYEIAFAAGDYFRALGVPVTDP
PFLDEIVVRFGIADSTANYHVPLLVSPYGYSTYKGT

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=114, Percent_Identity=37.719298245614, Blast_Score=78, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115532922, Length=117, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115532920, Length=117, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24652571, Length=116, Percent_Identity=40.5172413793103, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 12843; Mature: 12711

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00769 TRANSTHYRETIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLSTHVLDTARGQAAANMRVELYRFESGERVHCLTMRTNADGRTDSPLLSGDRIATGH
CCCCCCCEECCCCCCCCCCEEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCEEECCC
YEIAFAAGDYFRALGVPVTDPPFLDEIVVRFGIADSTANYHVPLLVSPYGYSTYKGT
EEEEEECCCCHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
ARLSTHVLDTARGQAAANMRVELYRFESGERVHCLTMRTNADGRTDSPLLSGDRIATGH
CCCCCCEECCCCCCCCCCEEEEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCEEECCC
YEIAFAAGDYFRALGVPVTDPPFLDEIVVRFGIADSTANYHVPLLVSPYGYSTYKGT
EEEEEECCCCHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]