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The map label for this gene is xerC [H]

Identifier: 116619488

GI number: 116619488

Start: 442656

End: 443567

Strand: Direct

Name: xerC [H]

Synonym: Acid_0347

Alternate gene names: 116619488

Gene position: 442656-443567 (Clockwise)

Preceding gene: 116619487

Following gene: 116619489

Centisome position: 4.44

GC content: 65.24

Gene sequence:

>912_bases
ATGCCATCGTCTGAACCGTCTGAACTGGAACGGCAAATCGTCCTTTACCTCGAAGACCTCGCCCGCGCCGGCAATTCCGA
GCACTCCATCCGCGCCTACGAATCCGACCTCCGCCAGTTCCTCGCCTTCCTCTCGCCCCCCGATCTGGCTCCGCCCGCGC
CCGCCGCCATCGATCTCCTCATCCTCCGCGAATGGCTCGCCGGGCTCTACCGCGACGATCTCAGCGCCGTCACTCTCCGC
CGCAAGCTCGCCGCCGTCCGCGGACTCTTTCGCTTCCTCCTCCGCGAAGGCGTTGTCCCACTCAACGTCGCCTGCCTCGT
GCGCACGCCCAAGGCGCCCAAAAAACTTCCCGAAGTCATGACCGCCGATCAGGTCAACTCCCTGATCGATGGCGTCGGCG
GCGTCGAACTCGAACGCCCTCACCCAGCCCGCGACCGCGCCATTTTCGAACTCCTCTATGGCTGCGGCATCCGCGTCAGT
GAACTCGCCGGTCTCAACCTGGAAGATATCGACCGCACCGAAGGTTGGCTGCGCGTCCGCGGCAAAGGCAAGAAGGAGCG
CCAGGTCCCGCTCCCCGGCCAGGCTGCCCAATCCCTCGAGCGCTACCTCGCCGAACGCCCCGTCGCCCGTGAACAGCCCG
CGGTCTTCGTCAATCACCGTCGTGCTCGCCTTACCACCCGCGGCATCAGCGGGATCGTCAAACTCTACGCCACGTACCTC
TCCAACGATCCCGGCATCCACCCCCACAGCTTCCGCCACGCCTACGCCACTCACCTGCTCGCCGATGGCGCGGACCTCCG
CGCCATTCAGGAACTGCTCGGCCACGCCCGCCTCTCCACCACGCAAAAATACACCCAGGTATCTTTGACCGACCTGATGG
CGGTCTACGACAAGGCGCATCCCAAGGCATGA

Upstream 100 bases:

>100_bases
CAACTCGAGGAGGCCGAACGCCAGCGCCTTCGCCGCGACAAGAAGGCGCGCCACGCCCTCGTCTGCCAGCGTGCGCTCGA
AGCGCTCGAAGAGTATCGCC

Downstream 100 bases:

>100_bases
TCGCGCGTATATGATCCCTGGCTTCCGCAAAGAGATCCGCCCCATGCTGCGCCTCGGCGTGCCTCTCGCCCTCGCCGAAC
TCGGCTGGATGGCGATGGGC

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPSSEPSELERQIVLYLEDLARAGNSEHSIRAYESDLRQFLAFLSPPDLAPPAPAAIDLLILREWLAGLYRDDLSAVTLR
RKLAAVRGLFRFLLREGVVPLNVACLVRTPKAPKKLPEVMTADQVNSLIDGVGGVELERPHPARDRAIFELLYGCGIRVS
ELAGLNLEDIDRTEGWLRVRGKGKKERQVPLPGQAAQSLERYLAERPVAREQPAVFVNHRRARLTTRGISGIVKLYATYL
SNDPGIHPHSFRHAYATHLLADGADLRAIQELLGHARLSTTQKYTQVSLTDLMAVYDKAHPKA

Sequences:

>Translated_303_residues
MPSSEPSELERQIVLYLEDLARAGNSEHSIRAYESDLRQFLAFLSPPDLAPPAPAAIDLLILREWLAGLYRDDLSAVTLR
RKLAAVRGLFRFLLREGVVPLNVACLVRTPKAPKKLPEVMTADQVNSLIDGVGGVELERPHPARDRAIFELLYGCGIRVS
ELAGLNLEDIDRTEGWLRVRGKGKKERQVPLPGQAAQSLERYLAERPVAREQPAVFVNHRRARLTTRGISGIVKLYATYL
SNDPGIHPHSFRHAYATHLLADGADLRAIQELLGHARLSTTQKYTQVSLTDLMAVYDKAHPKA
>Mature_302_residues
PSSEPSELERQIVLYLEDLARAGNSEHSIRAYESDLRQFLAFLSPPDLAPPAPAAIDLLILREWLAGLYRDDLSAVTLRR
KLAAVRGLFRFLLREGVVPLNVACLVRTPKAPKKLPEVMTADQVNSLIDGVGGVELERPHPARDRAIFELLYGCGIRVSE
LAGLNLEDIDRTEGWLRVRGKGKKERQVPLPGQAAQSLERYLAERPVAREQPAVFVNHRRARLTTRGISGIVKLYATYLS
NDPGIHPHSFRHAYATHLLADGADLRAIQELLGHARLSTTQKYTQVSLTDLMAVYDKAHPKA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=272, Percent_Identity=35.6617647058824, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1789261, Length=284, Percent_Identity=38.3802816901408, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790768, Length=160, Percent_Identity=30.625, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790767, Length=193, Percent_Identity=27.979274611399, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33741; Mature: 33610

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSEPSELERQIVLYLEDLARAGNSEHSIRAYESDLRQFLAFLSPPDLAPPAPAAIDLL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ILREWLAGLYRDDLSAVTLRRKLAAVRGLFRFLLREGVVPLNVACLVRTPKAPKKLPEVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHH
TADQVNSLIDGVGGVELERPHPARDRAIFELLYGCGIRVSELAGLNLEDIDRTEGWLRVR
HHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHCCCCHHHHCCCCHHHHHCCCCEEEEC
GKGKKERQVPLPGQAAQSLERYLAERPVAREQPAVFVNHRRARLTTRGISGIVKLYATYL
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHH
SNDPGIHPHSFRHAYATHLLADGADLRAIQELLGHARLSTTQKYTQVSLTDLMAVYDKAH
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PKA
CCC
>Mature Secondary Structure 
PSSEPSELERQIVLYLEDLARAGNSEHSIRAYESDLRQFLAFLSPPDLAPPAPAAIDLL
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ILREWLAGLYRDDLSAVTLRRKLAAVRGLFRFLLREGVVPLNVACLVRTPKAPKKLPEVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHH
TADQVNSLIDGVGGVELERPHPARDRAIFELLYGCGIRVSELAGLNLEDIDRTEGWLRVR
HHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHCCCCHHHHCCCCHHHHHCCCCEEEEC
GKGKKERQVPLPGQAAQSLERYLAERPVAREQPAVFVNHRRARLTTRGISGIVKLYATYL
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHH
SNDPGIHPHSFRHAYATHLLADGADLRAIQELLGHARLSTTQKYTQVSLTDLMAVYDKAH
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PKA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA