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The map label for this gene is lytR [H]

Identifier: 116496028

GI number: 116496028

Start: 2579495

End: 2580199

Strand: Direct

Name: lytR [H]

Synonym: LSEI_2599

Alternate gene names: 116496028

Gene position: 2579495-2580199 (Clockwise)

Preceding gene: 116496027

Following gene: 116496029

Centisome position: 89.09

GC content: 47.94

Gene sequence:

>705_bases
ATGCACATTGCCATCATTGGCGATCAGGCAGCCACGCGACAAGCAACAACTCAATTGCTTAGCCAACTGACCACGCCCAC
GCAGCCTTTACAAGTGACGGCTTATCCAACTGCAGAGGCCTTTCTTTTTGCTGATCAGCCGGCTGATCTGTTGTTGCTTG
ATATCAAGTTAGGTTCAGGCATGGATGGGATGACGCTTGCAAAGCAGATTCGGGAGCACGATGCGGCGACGGCGATTGCG
TTTGTCAGTAACTATGATGAATTCGTTTTTGACGGTTATGATGTCAACGCGCTTGATTATGTCATCAAACCGATTACAAG
TGACAAGCTGCAGCATCTCATCAGCAAAGTCGCCGCGCAAACGCAACCAAAGCTGTTGGTCTTCACCACCGCCAACGGCA
TTCAGCGTGTCGCCATGTATGATATCAGTGCCATCGAAGTAACCGATCATCGCTTGCAGGTGCACACCCAGAAAATGACG
TACACGGTCGCTGGTCAACTAAAAGAGTTTCTTCCTCAACTCGACGAAAATTTCATTCAAATCTATCGATCAATTGTCAT
CAACCTCAATTTTTTGTCGCAACTTGAGAAAAACACCGTCGTCATGGCTGATGGTACCAGTTACCCGGTTTCTCGGCAAC
AAGCACCGCTCGTCAAACAAGCCTTCTTTAAACATTTTCGGGGGTTAGCTCATGACAGTGAATGA

Upstream 100 bases:

>100_bases
AAAAAGCTGACTCACCCTGACTAGCTTTCTGGAAAAGCGACCAAATGATTGGTACAGTTGCAGTACAATGAACTAAATTC
AGAAAAGGAGACCTCTATCC

Downstream 100 bases:

>100_bases
ATGGTGGTGGCTAGCCACATTCGGCCTGTTGACAGTTGGCTGTTGCCTGCTTCTATGGTGGACCTTCCGCCGACAACAAA
ATTGGCCTGTGCGCGGTTTG

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MHIAIIGDQAATRQATTQLLSQLTTPTQPLQVTAYPTAEAFLFADQPADLLLLDIKLGSGMDGMTLAKQIREHDAATAIA
FVSNYDEFVFDGYDVNALDYVIKPITSDKLQHLISKVAAQTQPKLLVFTTANGIQRVAMYDISAIEVTDHRLQVHTQKMT
YTVAGQLKEFLPQLDENFIQIYRSIVINLNFLSQLEKNTVVMADGTSYPVSRQQAPLVKQAFFKHFRGLAHDSE

Sequences:

>Translated_234_residues
MHIAIIGDQAATRQATTQLLSQLTTPTQPLQVTAYPTAEAFLFADQPADLLLLDIKLGSGMDGMTLAKQIREHDAATAIA
FVSNYDEFVFDGYDVNALDYVIKPITSDKLQHLISKVAAQTQPKLLVFTTANGIQRVAMYDISAIEVTDHRLQVHTQKMT
YTVAGQLKEFLPQLDENFIQIYRSIVINLNFLSQLEKNTVVMADGTSYPVSRQQAPLVKQAFFKHFRGLAHDSE
>Mature_234_residues
MHIAIIGDQAATRQATTQLLSQLTTPTQPLQVTAYPTAEAFLFADQPADLLLLDIKLGSGMDGMTLAKQIREHDAATAIA
FVSNYDEFVFDGYDVNALDYVIKPITSDKLQHLISKVAAQTQPKLLVFTTANGIQRVAMYDISAIEVTDHRLQVHTQKMT
YTVAGQLKEFLPQLDENFIQIYRSIVINLNFLSQLEKNTVVMADGTSYPVSRQQAPLVKQAFFKHFRGLAHDSE

Specific function: Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=206, Percent_Identity=24.7572815533981, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26074; Mature: 26074

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIAIIGDQAATRQATTQLLSQLTTPTQPLQVTAYPTAEAFLFADQPADLLLLDIKLGSG
CEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCCEEEEEEEECCC
MDGMTLAKQIREHDAATAIAFVSNYDEFVFDGYDVNALDYVIKPITSDKLQHLISKVAAQ
CCHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHC
TQPKLLVFTTANGIQRVAMYDISAIEVTDHRLQVHTQKMTYTVAGQLKEFLPQLDENFIQ
CCCCEEEEEECCCHHHHHHEECEEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
IYRSIVINLNFLSQLEKNTVVMADGTSYPVSRQQAPLVKQAFFKHFRGLAHDSE
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHIAIIGDQAATRQATTQLLSQLTTPTQPLQVTAYPTAEAFLFADQPADLLLLDIKLGSG
CEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCCEEEEEEEECCC
MDGMTLAKQIREHDAATAIAFVSNYDEFVFDGYDVNALDYVIKPITSDKLQHLISKVAAQ
CCHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHC
TQPKLLVFTTANGIQRVAMYDISAIEVTDHRLQVHTQKMTYTVAGQLKEFLPQLDENFIQ
CCCCEEEEEECCCHHHHHHEECEEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
IYRSIVINLNFLSQLEKNTVVMADGTSYPVSRQQAPLVKQAFFKHFRGLAHDSE
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]