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The map label for this gene is prsA [H]

Identifier: 116495723

GI number: 116495723

Start: 2270025

End: 2270924

Strand: Direct

Name: prsA [H]

Synonym: LSEI_2271

Alternate gene names: 116495723

Gene position: 2270025-2270924 (Clockwise)

Preceding gene: 116495721

Following gene: 116495726

Centisome position: 78.4

GC content: 42.44

Gene sequence:

>900_bases
ATGAAGAAAAAAATGCGCCTTAAAGTATTATTGGCAAGTACCGCAACTGCTTTACTGCTGCTAAGCGGTTGTCAGTCAAA
TCAGGCCGACCAAACAGTTGCGACCTATTCAGGCGGCAAGGTGACTGAAAGTAACTTCTATAAGGAACTCAAACAGTCAC
CAACGACAAAGACCATGCTTGCTAACATGCTCATTTATCGTGCATTGAATCATGCCTATGGAAAATCGGTTAGCACTAAA
ACAGTTAATGACGCCTATGATAGCTACAAACAACAATACGGCGAAAATTTCGATGCTTTCTTAAGTCAAAACGGTTTCAG
TCGCAGTAGCTTCAAGGAAAGCCTACGAACCAACTTTTTAAGTGAAGTTGCACTGAAAAAGTTAAAAAAGGTTTCTGAAA
GCCAGCTCAAGGCCGCTTGGAAGACCTATCAGCCCAAAGTGACTGTCCAACATATTCTAACTAGCGACGAGGACACTGCT
AAGCAAGTTATCAGTGATTTAGCAGCTGGCCAGGATTTTGCCACGCTTGCGAAAACTGATTCCATTGATACTGCGACTAA
AGATAACGGCGGGAAGATTAGTTTTGAATCAAACAATAAAACGCTCGATGCCACATTTAAGGATGCTGCCTACAAATTAA
AAAATGGTGACTACACGCAGACACCAGTCAAAGTGACAGACGGGTATGAAGTTATTAAAATGATTAACCATCCCGCCAAA
GGCACCTTTACTAGCAGTAAAAAGGCGCTAACCGCCAGCGTTTACGCTAAATGGTCCCGCGATTCAAGCATCATGCAACG
CGTTATCAGTCAGGTATTGAAGAACCAGAATGTGACGATTAAAGACAAGGATCTTGCGGATGCGCTAGATAGTTATAAGA
AGCTTGCGACAACGAATTAA

Upstream 100 bases:

>100_bases
GCATTATTAGAAAATGAGTATTTGCATTGAAATTCTCAATTGCCAACGCTAGAATAAATACACAACGTTTACTGTAAGCA
TTTCAGAGGAGACCTAGTCG

Downstream 100 bases:

>100_bases
GGCTTAACCGAGTAAGCTGAAATAACAGCCAGTTCTTTTAGAAATTGGACATCAACGCCCCGAAAGTCATAGCAACATGA
CTTTCGGGGCGTTTTATGTA

Product: peptidylprolyl isomerase

Products: NA

Alternate protein names: Protease maturation protein prtM [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MKKKMRLKVLLASTATALLLLSGCQSNQADQTVATYSGGKVTESNFYKELKQSPTTKTMLANMLIYRALNHAYGKSVSTK
TVNDAYDSYKQQYGENFDAFLSQNGFSRSSFKESLRTNFLSEVALKKLKKVSESQLKAAWKTYQPKVTVQHILTSDEDTA
KQVISDLAAGQDFATLAKTDSIDTATKDNGGKISFESNNKTLDATFKDAAYKLKNGDYTQTPVKVTDGYEVIKMINHPAK
GTFTSSKKALTASVYAKWSRDSSIMQRVISQVLKNQNVTIKDKDLADALDSYKKLATTN

Sequences:

>Translated_299_residues
MKKKMRLKVLLASTATALLLLSGCQSNQADQTVATYSGGKVTESNFYKELKQSPTTKTMLANMLIYRALNHAYGKSVSTK
TVNDAYDSYKQQYGENFDAFLSQNGFSRSSFKESLRTNFLSEVALKKLKKVSESQLKAAWKTYQPKVTVQHILTSDEDTA
KQVISDLAAGQDFATLAKTDSIDTATKDNGGKISFESNNKTLDATFKDAAYKLKNGDYTQTPVKVTDGYEVIKMINHPAK
GTFTSSKKALTASVYAKWSRDSSIMQRVISQVLKNQNVTIKDKDLADALDSYKKLATTN
>Mature_299_residues
MKKKMRLKVLLASTATALLLLSGCQSNQADQTVATYSGGKVTESNFYKELKQSPTTKTMLANMLIYRALNHAYGKSVSTK
TVNDAYDSYKQQYGENFDAFLSQNGFSRSSFKESLRTNFLSEVALKKLKKVSESQLKAAWKTYQPKVTVQHILTSDEDTA
KQVISDLAAGQDFATLAKTDSIDTATKDNGGKISFESNNKTLDATFKDAAYKLKNGDYTQTPVKVTDGYEVIKMINHPAK
GTFTSSKKALTASVYAKWSRDSSIMQRVISQVLKNQNVTIKDKDLADALDSYKKLATTN

Specific function: This protein is essential for production of active forms of the serine proteinase located in or secreted from the cell envelope [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 33085; Mature: 33085

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKMRLKVLLASTATALLLLSGCQSNQADQTVATYSGGKVTESNFYKELKQSPTTKTML
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHH
ANMLIYRALNHAYGKSVSTKTVNDAYDSYKQQYGENFDAFLSQNGFSRSSFKESLRTNFL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHH
SEVALKKLKKVSESQLKAAWKTYQPKVTVQHILTSDEDTAKQVISDLAAGQDFATLAKTD
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHCC
SIDTATKDNGGKISFESNNKTLDATFKDAAYKLKNGDYTQTPVKVTDGYEVIKMINHPAK
CCCCCCCCCCCEEEECCCCCEEEEHHHHHHHEECCCCCCCCCEEECCCHHHHHHHCCCCC
GTFTSSKKALTASVYAKWSRDSSIMQRVISQVLKNQNVTIKDKDLADALDSYKKLATTN
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKKMRLKVLLASTATALLLLSGCQSNQADQTVATYSGGKVTESNFYKELKQSPTTKTML
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHH
ANMLIYRALNHAYGKSVSTKTVNDAYDSYKQQYGENFDAFLSQNGFSRSSFKESLRTNFL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHH
SEVALKKLKKVSESQLKAAWKTYQPKVTVQHILTSDEDTAKQVISDLAAGQDFATLAKTD
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHCC
SIDTATKDNGGKISFESNNKTLDATFKDAAYKLKNGDYTQTPVKVTDGYEVIKMINHPAK
CCCCCCCCCCCEEEECCCCCEEEEHHHHHHHEECCCCCCCCCEEECCCHHHHHHHCCCCC
GTFTSSKKALTASVYAKWSRDSSIMQRVISQVLKNQNVTIKDKDLADALDSYKKLATTN
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2708318; 2501630; 11473599; 3278687; 2166472; 1906066 [H]