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The map label for this gene is insK [C]

Identifier: 116494798

GI number: 116494798

Start: 1292516

End: 1294051

Strand: Direct

Name: insK [C]

Synonym: LSEI_1309

Alternate gene names: 116494798

Gene position: 1292516-1294051 (Clockwise)

Preceding gene: 116494797

Following gene: 116494799

Centisome position: 44.64

GC content: 44.79

Gene sequence:

>1536_bases
ATGTATTCAAAAGCAGCTAAAAAACGAGCAATCGAGCTCTTCTACCAATATCATCGTTCATGGAGTGCAGTAGTCAGAGA
ATTAGGCTATCCGTCTTTAGGCGCATTAAAACGATGGATTATAGATTACGAACAAGATGCCAAAAATGCGCTTGATGAGT
CCCCACGAAAGAGAAAATCAAAGTACTCTGATGTGCAACGACAAACTGCAGTGGATCACTTCTTTGAACATGGGCAATTC
ATCACAAAAACGGTCAGAGCGCTAGGTTATCCATCACGACAGCTTCTTCGTGAGTGGCTATTAACAGATCCTCGTTATGA
TATTTCACTGCGTAGCCGTACTGTTATGGTTAAGCCTGCTACGCCGGCTGACGTCAAGGCTAAGGCTGTGGAGGCACTCT
ATAAACGAGAAGTCCCTGCCAGAAAAATTGCGGAAAATTTCGGGGTTAGCCGTGAAACACTTTACGCCTGGAAGCGAGAT
GCACTCGGTGAAAATTTCCCGGCCAAGCAGACGCCTAGTTTATCAAATGAAGAAAAAAATCAAGCAAACATCACCCCCGA
AGTTTCAGATCTCCAAGTCCGCATCACAGAGCTTGAACTTCAGAATGATATTCTTCTTCAAGTAAACGCCCTCCTAAAAA
AAGATCTGGGCATCAACCAACTCAATCTAACTAATCGAGAAAAGGTTCAGGTGATTGATGCCCTGCGTGATAGATATTCG
CTTAATACGCTGCGTAATGCCCTCCGATTATCAAAGAGTAGCTATTTCTATCAACGTGACGCCATCGCCAAGGGCGATAA
GTACAAAGCAGTACGTCCACGCTTGAAGATTATTTTTGAGCAGAACTACAAGAGCTATGGGTATCGCCGAATGAAGATGG
AACTCGACGATGAGGGGATCCAACTCTCTGAAAAAGTGATCCGCCGGTTAATGGCTGAGGAAGGATTGAAAGTCACCATC
ACACGCTGTCGAAAATACAGCTCGTACGCGGGTGAAATAACGCCAGCCGTTGCGAATATCCTTGACCGAGATTTTCAATC
AGAAGTCCCAAATCAAAAGCTAGTCACAGATATTACAGAGTTTTCTATCCAGGCCGGGAAAGTATATCTATCACCACTCA
TTGATTGTTTTGATGGCCAAATTACGAGTTGGACCATTGGCACTAGCCCAAACGCTGAACTTGTCAACACAATGCTTAGC
ACAGCGGCCAAAGTATTGCCCGCCAGTGAAAAAACCATCGTTCATTCCGACAGAGGCGCTCACTACCGCTGGTCAGGCTG
GATTGAACTGATGGACGAGTTTGGCTTTACACGATCGATGTCGAAGAAAGGTAGCACTCCAGACAATGCTCAATCGGAGA
GCTTCTTTGGCCATCTCAAGACAGAGTTCTTTTACAATCGAAGCTGGCTTGGAAAGTCAATTGATGATTTCACACAAGCA
CTCAATGAGTATATTGAGTGGTATAACACCAAACGAAGAAAAAAAGTTTTAGGAGGAAAGAGCCCGCAGGAATACCGTCA
GAGCAAGGTAGCTTGA

Upstream 100 bases:

>100_bases
GTCTGATCTCCTTGATCAGGCTGTTTTTGTGTCATTTGGTTATCGCTAATGGTGAATGGGGCGTGCGGACAAATTCCTGG
ACTTAGGGTATGATGTCATT

Downstream 100 bases:

>100_bases
TGGTGAAAGTCCAGAAAAACGTCCGCACGCCCATGCTGTGAGCATGGCAACAGCTAATTTTTACAAGAAGATGAGAAACG
GCTAATATTTCAGTTAGTTA

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MYSKAAKKRAIELFYQYHRSWSAVVRELGYPSLGALKRWIIDYEQDAKNALDESPRKRKSKYSDVQRQTAVDHFFEHGQF
ITKTVRALGYPSRQLLREWLLTDPRYDISLRSRTVMVKPATPADVKAKAVEALYKREVPARKIAENFGVSRETLYAWKRD
ALGENFPAKQTPSLSNEEKNQANITPEVSDLQVRITELELQNDILLQVNALLKKDLGINQLNLTNREKVQVIDALRDRYS
LNTLRNALRLSKSSYFYQRDAIAKGDKYKAVRPRLKIIFEQNYKSYGYRRMKMELDDEGIQLSEKVIRRLMAEEGLKVTI
TRCRKYSSYAGEITPAVANILDRDFQSEVPNQKLVTDITEFSIQAGKVYLSPLIDCFDGQITSWTIGTSPNAELVNTMLS
TAAKVLPASEKTIVHSDRGAHYRWSGWIELMDEFGFTRSMSKKGSTPDNAQSESFFGHLKTEFFYNRSWLGKSIDDFTQA
LNEYIEWYNTKRRKKVLGGKSPQEYRQSKVA

Sequences:

>Translated_511_residues
MYSKAAKKRAIELFYQYHRSWSAVVRELGYPSLGALKRWIIDYEQDAKNALDESPRKRKSKYSDVQRQTAVDHFFEHGQF
ITKTVRALGYPSRQLLREWLLTDPRYDISLRSRTVMVKPATPADVKAKAVEALYKREVPARKIAENFGVSRETLYAWKRD
ALGENFPAKQTPSLSNEEKNQANITPEVSDLQVRITELELQNDILLQVNALLKKDLGINQLNLTNREKVQVIDALRDRYS
LNTLRNALRLSKSSYFYQRDAIAKGDKYKAVRPRLKIIFEQNYKSYGYRRMKMELDDEGIQLSEKVIRRLMAEEGLKVTI
TRCRKYSSYAGEITPAVANILDRDFQSEVPNQKLVTDITEFSIQAGKVYLSPLIDCFDGQITSWTIGTSPNAELVNTMLS
TAAKVLPASEKTIVHSDRGAHYRWSGWIELMDEFGFTRSMSKKGSTPDNAQSESFFGHLKTEFFYNRSWLGKSIDDFTQA
LNEYIEWYNTKRRKKVLGGKSPQEYRQSKVA
>Mature_511_residues
MYSKAAKKRAIELFYQYHRSWSAVVRELGYPSLGALKRWIIDYEQDAKNALDESPRKRKSKYSDVQRQTAVDHFFEHGQF
ITKTVRALGYPSRQLLREWLLTDPRYDISLRSRTVMVKPATPADVKAKAVEALYKREVPARKIAENFGVSRETLYAWKRD
ALGENFPAKQTPSLSNEEKNQANITPEVSDLQVRITELELQNDILLQVNALLKKDLGINQLNLTNREKVQVIDALRDRYS
LNTLRNALRLSKSSYFYQRDAIAKGDKYKAVRPRLKIIFEQNYKSYGYRRMKMELDDEGIQLSEKVIRRLMAEEGLKVTI
TRCRKYSSYAGEITPAVANILDRDFQSEVPNQKLVTDITEFSIQAGKVYLSPLIDCFDGQITSWTIGTSPNAELVNTMLS
TAAKVLPASEKTIVHSDRGAHYRWSGWIELMDEFGFTRSMSKKGSTPDNAQSESFFGHLKTEFFYNRSWLGKSIDDFTQA
LNEYIEWYNTKRRKKVLGGKSPQEYRQSKVA

Specific function: Probably involved in the transposition of insertion sequence IS1353 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=263, Percent_Identity=24.7148288973384, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1789981, Length=278, Percent_Identity=39.568345323741, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI1788405, Length=291, Percent_Identity=27.8350515463918, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787263, Length=291, Percent_Identity=27.8350515463918, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786753, Length=291, Percent_Identity=27.8350515463918, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786570, Length=291, Percent_Identity=27.8350515463918, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786490, Length=291, Percent_Identity=27.8350515463918, Blast_Score=109, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337
- InterPro:   IPR002514 [H]

Pfam domain/function: PF00665 rve; PF01527 Transposase_8 [H]

EC number: NA

Molecular weight: Translated: 58997; Mature: 58997

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSKAAKKRAIELFYQYHRSWSAVVRELGYPSLGALKRWIIDYEQDAKNALDESPRKRKS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHH
KYSDVQRQTAVDHFFEHGQFITKTVRALGYPSRQLLREWLLTDPRYDISLRSRTVMVKPA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEECCEEEEEECC
TPADVKAKAVEALYKREVPARKIAENFGVSRETLYAWKRDALGENFPAKQTPSLSNEEKN
CCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QANITPEVSDLQVRITELELQNDILLQVNALLKKDLGINQLNLTNREKVQVIDALRDRYS
CCCCCCCCCCCEEEEEEEHHCCCHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHH
LNTLRNALRLSKSSYFYQRDAIAKGDKYKAVRPRLKIIFEQNYKSYGYRRMKMELDDEGI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCHHHHHHHHCCHHHCCEEEEEEEECCCCC
QLSEKVIRRLMAEEGLKVTITRCRKYSSYAGEITPAVANILDRDFQSEVPNQKLVTDITE
HHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FSIQAGKVYLSPLIDCFDGQITSWTIGTSPNAELVNTMLSTAAKVLPASEKTIVHSDRGA
HHHHCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCC
HYRWSGWIELMDEFGFTRSMSKKGSTPDNAQSESFFGHLKTEFFYNRSWLGKSIDDFTQA
CEEHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHH
LNEYIEWYNTKRRKKVLGGKSPQEYRQSKVA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
>Mature Secondary Structure
MYSKAAKKRAIELFYQYHRSWSAVVRELGYPSLGALKRWIIDYEQDAKNALDESPRKRKS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHH
KYSDVQRQTAVDHFFEHGQFITKTVRALGYPSRQLLREWLLTDPRYDISLRSRTVMVKPA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEECCEEEEEECC
TPADVKAKAVEALYKREVPARKIAENFGVSRETLYAWKRDALGENFPAKQTPSLSNEEKN
CCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QANITPEVSDLQVRITELELQNDILLQVNALLKKDLGINQLNLTNREKVQVIDALRDRYS
CCCCCCCCCCCEEEEEEEHHCCCHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHH
LNTLRNALRLSKSSYFYQRDAIAKGDKYKAVRPRLKIIFEQNYKSYGYRRMKMELDDEGI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCHHHHHHHHCCHHHCCEEEEEEEECCCCC
QLSEKVIRRLMAEEGLKVTITRCRKYSSYAGEITPAVANILDRDFQSEVPNQKLVTDITE
HHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FSIQAGKVYLSPLIDCFDGQITSWTIGTSPNAELVNTMLSTAAKVLPASEKTIVHSDRGA
HHHHCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCC
HYRWSGWIELMDEFGFTRSMSKKGSTPDNAQSESFFGHLKTEFFYNRSWLGKSIDDFTQA
CEEHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHH
LNEYIEWYNTKRRKKVLGGKSPQEYRQSKVA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8755869; 12499211 [H]