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The map label for this gene is ldh [H]

Identifier: 116494799

GI number: 116494799

Start: 1294240

End: 1295130

Strand: Direct

Name: ldh [H]

Synonym: LSEI_1310

Alternate gene names: 116494799

Gene position: 1294240-1295130 (Clockwise)

Preceding gene: 116494798

Following gene: 116494800

Centisome position: 44.7

GC content: 46.24

Gene sequence:

>891_bases
ATGCAAAGAGTCGTGGTGAGCGGTGCCAGTATCGGGACCCAAGGGCTTTTAGAAACATTGATTGCATCACAGTTGCTGTT
GACGGTGGGTTGTTATGAACCAGATGAATCATTGATTGATATGGTTGGGTTGACAGCTTTAAGTCAAATATGTCAAAACA
CATTTGCAAAAGTCACGCCGAAAGTTTTAAAAGCGGCGGATATTTTAATCTTGACCGATACGGGGTCACCTGATGCCGAT
GATTTTATTGAGACGAATATTGCGGCAATTCGCAAAGTTCTCAATTCAGCGATGGCGGCGGGCTTCACAGGTAGAATCAT
TGTTGCGATGACACGTGATGAACTTTTTACGTATTTTGCGCAACGTTTTTCCGGAGTGAATAAAAGTCAGGTTGTTGGAC
TTGGTACGTTCGGTGCAACGTGGCGATTTGAACAATTTCTGGCTGCTAGGTTGGCAGTACCGGCGAAACATGTGACGGCT
TATGTGGTAGGTACGCGACAAGCCCCAGTGTTGATTTGGAGCCGAGCTTACGTTGGTGCAACGCCGGTTTTGCGCTTATT
AAATGATCAGACGATTTTTACTGATGGCTTGGATGCGGTTCGAAGCTTTTTGAGGAGTCCCTTGACTGTCTTGCTTGGGA
GGTTGGTGATTCCGATTATTGCGGCGTATAGTGGCGATAGTTTGATTGGCACGCTGACGCATCTGATGGATGTAGAGGAT
GACACAGGTCAGGTTTATAGTTCGCCAGTCCTCTTGAATGATAGCGGCGTTGTGACGCTCGCCACAGTTGCTGGTTCGGA
TGATGAGGAAGCTGCGTTGAGTCAAACGAAACAAACTGTACAGGATCAAATTAAGGCGATAGAACAAGGAGCTAGTAAAC
ATGAAACCTAA

Upstream 100 bases:

>100_bases
TTCAGTTAGTTAACAATTGCGTCTAAACCCCTTTTTAATTTTGTCTTAAGATTCTGCTTCCGTTAAAATGTAACTAATGG
AGTGGAGGGGAAGGGTTTTC

Downstream 100 bases:

>100_bases
TTATGCCTATCCACTCGACATTGACTGGACAACTGCCGAAAAAGTAAAAGTCACGACCTTTTATACCTTAGTCGAAGATG
CATATGAACACGGTGTTGAT

Product: malate/lactate dehydrogenase

Products: NA

Alternate protein names: L-LDH [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MQRVVVSGASIGTQGLLETLIASQLLLTVGCYEPDESLIDMVGLTALSQICQNTFAKVTPKVLKAADILILTDTGSPDAD
DFIETNIAAIRKVLNSAMAAGFTGRIIVAMTRDELFTYFAQRFSGVNKSQVVGLGTFGATWRFEQFLAARLAVPAKHVTA
YVVGTRQAPVLIWSRAYVGATPVLRLLNDQTIFTDGLDAVRSFLRSPLTVLLGRLVIPIIAAYSGDSLIGTLTHLMDVED
DTGQVYSSPVLLNDSGVVTLATVAGSDDEEAALSQTKQTVQDQIKAIEQGASKHET

Sequences:

>Translated_296_residues
MQRVVVSGASIGTQGLLETLIASQLLLTVGCYEPDESLIDMVGLTALSQICQNTFAKVTPKVLKAADILILTDTGSPDAD
DFIETNIAAIRKVLNSAMAAGFTGRIIVAMTRDELFTYFAQRFSGVNKSQVVGLGTFGATWRFEQFLAARLAVPAKHVTA
YVVGTRQAPVLIWSRAYVGATPVLRLLNDQTIFTDGLDAVRSFLRSPLTVLLGRLVIPIIAAYSGDSLIGTLTHLMDVED
DTGQVYSSPVLLNDSGVVTLATVAGSDDEEAALSQTKQTVQDQIKAIEQGASKHET
>Mature_296_residues
MQRVVVSGASIGTQGLLETLIASQLLLTVGCYEPDESLIDMVGLTALSQICQNTFAKVTPKVLKAADILILTDTGSPDAD
DFIETNIAAIRKVLNSAMAAGFTGRIIVAMTRDELFTYFAQRFSGVNKSQVVGLGTFGATWRFEQFLAARLAVPAKHVTA
YVVGTRQAPVLIWSRAYVGATPVLRLLNDQTIFTDGLDAVRSFLRSPLTVLLGRLVIPIIAAYSGDSLIGTLTHLMDVED
DTGQVYSSPVLLNDSGVVTLATVAGSDDEEAALSQTKQTVQDQIKAIEQGASKHET

Specific function: Unknown

COG id: COG0039

COG function: function code C; Malate/lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH/MDH superfamily. LDH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001557
- InterPro:   IPR011304
- InterPro:   IPR018177
- InterPro:   IPR022383
- InterPro:   IPR001236
- InterPro:   IPR015955
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02866 Ldh_1_C; PF00056 Ldh_1_N [H]

EC number: =1.1.1.27 [H]

Molecular weight: Translated: 31637; Mature: 31637

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRVVVSGASIGTQGLLETLIASQLLLTVGCYEPDESLIDMVGLTALSQICQNTFAKVTP
CCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCH
KVLKAADILILTDTGSPDADDFIETNIAAIRKVLNSAMAAGFTGRIIVAMTRDELFTYFA
HHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHH
QRFSGVNKSQVVGLGTFGATWRFEQFLAARLAVPAKHVTAYVVGTRQAPVLIWSRAYVGA
HHHCCCCHHHEEEEECCCCHHHHHHHHHHHHHCCHHHHEEEEEECCCCCEEEEECHHHCH
TPVLRLLNDQTIFTDGLDAVRSFLRSPLTVLLGRLVIPIIAAYSGDSLIGTLTHLMDVED
HHHHHHHCCCCEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
DTGQVYSSPVLLNDSGVVTLATVAGSDDEEAALSQTKQTVQDQIKAIEQGASKHET
CCCCEECCCEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQRVVVSGASIGTQGLLETLIASQLLLTVGCYEPDESLIDMVGLTALSQICQNTFAKVTP
CCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCH
KVLKAADILILTDTGSPDADDFIETNIAAIRKVLNSAMAAGFTGRIIVAMTRDELFTYFA
HHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHH
QRFSGVNKSQVVGLGTFGATWRFEQFLAARLAVPAKHVTAYVVGTRQAPVLIWSRAYVGA
HHHCCCCHHHEEEEECCCCHHHHHHHHHHHHHCCHHHHEEEEEECCCCCEEEEECHHHCH
TPVLRLLNDQTIFTDGLDAVRSFLRSPLTVLLGRLVIPIIAAYSGDSLIGTLTHLMDVED
HHHHHHHCCCCEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
DTGQVYSSPVLLNDSGVVTLATVAGSDDEEAALSQTKQTVQDQIKAIEQGASKHET
CCCCEECCCEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6352452; 3026926; 3675869; 6618448; 1731077 [H]