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The map label for this gene is atpH

Identifier: 116494659

GI number: 116494659

Start: 1146813

End: 1147358

Strand: Direct

Name: atpH

Synonym: LSEI_1163

Alternate gene names: 116494659

Gene position: 1146813-1147358 (Clockwise)

Preceding gene: 116494658

Following gene: 116494660

Centisome position: 39.61

GC content: 49.63

Gene sequence:

>546_bases
ATGGCAGTCACTAATCAGATGGTCGCACCCCGCTATGCCAAAGCTTTATTGGAAGCGGCACAAGATCAAAATCAGGTGGA
GACGGTCCATGAAGAGTTACAAGCGCTACAGTCTGTCTTTAACGACAACCCAACGATCTTGACTATTTTTGATAACGCTC
GAATCACGGCAGCTGATAAAGATGCCTTGATGACAACCTTAACCAAGGATGCTAGCCCGCTGGTCGCTAACTTGTTGAAG
TTAACCCAGCAATATGGGCGATTCGGAGCATTACCAGCCATCATCAGCGCGTTTAACCAAGCGTACGATGAGGAAGCCGG
GATTATTGCGGCGACTGTGACGACTGCAGTTGCTTTGTCAGCAGATCAAGCTGATGCTTTGCGCAGTACCATTGCTGCGC
GTTTTGGCATGAAATCGACCCAACTGGATCAAGTCGTTGATCCAAGCGTCATCGGCGGTGTGCGAATTCAAGCACGCGGT
TCGGTTATCGATGGTACGGTCAAGCACCGTTTCGATAAGATGAAAGCTGCACTGCTGGCAGACTAA

Upstream 100 bases:

>100_bases
CTAAGTTTGACCATCGCGCAAAAACTGATCGGTAAGGAACTCAATGCAGACGATCAAAAAGGTTTGATCGATGACTATAT
TAAACGGTTAGGTGATGCAA

Downstream 100 bases:

>100_bases
TGAGTAAGTAAAAGAGGTGAACCGGATGAGCATCAAGACTGAGGAAATCAGTTCTCTGATCAAAAAACAACTTGAAGGAT
ATCAGGACGATTTGGCGGCT

Product: F0F1-type ATP synthase, delta subunit

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MAVTNQMVAPRYAKALLEAAQDQNQVETVHEELQALQSVFNDNPTILTIFDNARITAADKDALMTTLTKDASPLVANLLK
LTQQYGRFGALPAIISAFNQAYDEEAGIIAATVTTAVALSADQADALRSTIAARFGMKSTQLDQVVDPSVIGGVRIQARG
SVIDGTVKHRFDKMKAALLAD

Sequences:

>Translated_181_residues
MAVTNQMVAPRYAKALLEAAQDQNQVETVHEELQALQSVFNDNPTILTIFDNARITAADKDALMTTLTKDASPLVANLLK
LTQQYGRFGALPAIISAFNQAYDEEAGIIAATVTTAVALSADQADALRSTIAARFGMKSTQLDQVVDPSVIGGVRIQARG
SVIDGTVKHRFDKMKAALLAD
>Mature_180_residues
AVTNQMVAPRYAKALLEAAQDQNQVETVHEELQALQSVFNDNPTILTIFDNARITAADKDALMTTLTKDASPLVANLLKL
TQQYGRFGALPAIISAFNQAYDEEAGIIAATVTTAVALSADQADALRSTIAARFGMKSTQLDQVVDPSVIGGVRIQARGS
VIDGTVKHRFDKMKAALLAD

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=171, Percent_Identity=26.9005847953216, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71984710, Length=179, Percent_Identity=28.4916201117318, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71984717, Length=179, Percent_Identity=28.4916201117318, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320504, Length=173, Percent_Identity=25.4335260115607, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_LACC3 (Q03A21)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_806393.1
- ProteinModelPortal:   Q03A21
- SMR:   Q03A21
- STRING:   Q03A21
- GeneID:   4420199
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_1163
- eggNOG:   COG0712
- HOGENOM:   HBG668108
- OMA:   AYDEEAG
- PhylomeDB:   Q03A21
- ProtClustDB:   CLSK2317917
- BioCyc:   LCAS321967:LSEI_1163-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 19361; Mature: 19230

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTNQMVAPRYAKALLEAAQDQNQVETVHEELQALQSVFNDNPTILTIFDNARITAADK
CCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEECCH
DALMTTLTKDASPLVANLLKLTQQYGRFGALPAIISAFNQAYDEEAGIIAATVTTAVALS
HHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHC
ADQADALRSTIAARFGMKSTQLDQVVDPSVIGGVRIQARGSVIDGTVKHRFDKMKAALLA
CHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHC
D
C
>Mature Secondary Structure 
AVTNQMVAPRYAKALLEAAQDQNQVETVHEELQALQSVFNDNPTILTIFDNARITAADK
CCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEECCH
DALMTTLTKDASPLVANLLKLTQQYGRFGALPAIISAFNQAYDEEAGIIAATVTTAVALS
HHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHC
ADQADALRSTIAARFGMKSTQLDQVVDPSVIGGVRIQARGSVIDGTVKHRFDKMKAALLA
CHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA