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The map label for this gene is purQ [H]

Identifier: 116493201

GI number: 116493201

Start: 1438464

End: 1439138

Strand: Reverse

Name: purQ [H]

Synonym: PEPE_1463

Alternate gene names: 116493201

Gene position: 1439138-1438464 (Counterclockwise)

Preceding gene: 116493202

Following gene: 116493200

Centisome position: 78.54

GC content: 40.0

Gene sequence:

>675_bases
ATGATTTACAGCATTATTCGTTTTCCAGGGTCTAATTGTGATTGGGATATGTACTATGTTTTGCGCGACGTTATGAACGT
TGAGCCTCAATTTGTGGACTATCGCGAAAAATCCTTACCGCAAGATACAGTTGCAGTCTTAATTCCAGGCGGTTTTTCAT
ATGGTGACTACTTACGAAGCGGCGCAATCGCACGTTTTTCTCCCATCATGGATGCTGTAAAAAAATTTGCCTATGCGGGA
AACCCAGTAATTGGAATTTGTAACGGATTTCAAATTTTAACCGAAGCCGGGCTGCTTCCGGGGGCCTTGCGATCGAATGA
TAGTTTGAATTTTATTTGTAAACCACAAAAATTAGTGGTTGAAAATAATCAGACTATCTTTACCAAACGTTTTGATTTAA
AACAGACCGTAATGTTTCCCATTGCCCATGGTGAAGGTAACTATTATTGTGATTCGGCTACTTTACAAGACTTAAAGGAT
CATCATCAAATTGTTTTACGTTATCAAAATAATCCCAACGGAAGTACAGACGATATTGCGGGAATTATCAATCAGAAAGG
CAATGTGCTAGGGATGATGCCCCATCCTGAACGCGCTAGTGAAGCCGTCCTAGGTGGCGAAGATGGCAAAATGCTGTTCC
AAAGTTTAATTGAAAGCATGACGCAAAATGTTTAA

Upstream 100 bases:

>100_bases
ATATTGAAGAGCAAGTTAGAAAAATGAGTGATGAGCTACTAGCAAACATTAACATGGAAACTTATCGATTTGAGATTAGC
AGGATTGAGGAGGACTAGCA

Downstream 100 bases:

>100_bases
TTAAAGGAGTTTTCGCAATGATGAAGGAATTAACACCTACCGAAATTCGAGATCAAAAATTGTATTTGCAATGGGGGATA
AGCGAAGACGAATATCAGAA

Product: phosphoribosylformylglycinamidine synthase domain-containing protein

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MIYSIIRFPGSNCDWDMYYVLRDVMNVEPQFVDYREKSLPQDTVAVLIPGGFSYGDYLRSGAIARFSPIMDAVKKFAYAG
NPVIGICNGFQILTEAGLLPGALRSNDSLNFICKPQKLVVENNQTIFTKRFDLKQTVMFPIAHGEGNYYCDSATLQDLKD
HHQIVLRYQNNPNGSTDDIAGIINQKGNVLGMMPHPERASEAVLGGEDGKMLFQSLIESMTQNV

Sequences:

>Translated_224_residues
MIYSIIRFPGSNCDWDMYYVLRDVMNVEPQFVDYREKSLPQDTVAVLIPGGFSYGDYLRSGAIARFSPIMDAVKKFAYAG
NPVIGICNGFQILTEAGLLPGALRSNDSLNFICKPQKLVVENNQTIFTKRFDLKQTVMFPIAHGEGNYYCDSATLQDLKD
HHQIVLRYQNNPNGSTDDIAGIINQKGNVLGMMPHPERASEAVLGGEDGKMLFQSLIESMTQNV
>Mature_224_residues
MIYSIIRFPGSNCDWDMYYVLRDVMNVEPQFVDYREKSLPQDTVAVLIPGGFSYGDYLRSGAIARFSPIMDAVKKFAYAG
NPVIGICNGFQILTEAGLLPGALRSNDSLNFICKPQKLVVENNQTIFTKRFDLKQTVMFPIAHGEGNYYCDSATLQDLKD
HHQIVLRYQNNPNGSTDDIAGIINQKGNVLGMMPHPERASEAVLGGEDGKMLFQSLIESMTQNV

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=213, Percent_Identity=28.6384976525822, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17553022, Length=231, Percent_Identity=28.1385281385281, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582111, Length=235, Percent_Identity=30.2127659574468, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582109, Length=235, Percent_Identity=30.2127659574468, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17137292, Length=235, Percent_Identity=30.2127659574468, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24984; Mature: 24984

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYSIIRFPGSNCDWDMYYVLRDVMNVEPQFVDYREKSLPQDTVAVLIPGGFSYGDYLRS
CEEEEEECCCCCCCCHHHHHHHHHHCCCCHHCCCHHHCCCCCEEEEEECCCCCHHHHHHC
GAIARFSPIMDAVKKFAYAGNPVIGICNGFQILTEAGLLPGALRSNDSLNFICKPQKLVV
CCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCCCCCCCCCEEEEECCCEEEE
ENNQTIFTKRFDLKQTVMFPIAHGEGNYYCDSATLQDLKDHHQIVLRYQNNPNGSTDDIA
ECCCEEEEEECCCCEEEEEEEEECCCCEEECCCHHHHHHCCEEEEEEECCCCCCCHHHHH
GIINQKGNVLGMMPHPERASEAVLGGEDGKMLFQSLIESMTQNV
HHHCCCCCEEEECCCCCCCCHHEECCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIYSIIRFPGSNCDWDMYYVLRDVMNVEPQFVDYREKSLPQDTVAVLIPGGFSYGDYLRS
CEEEEEECCCCCCCCHHHHHHHHHHCCCCHHCCCHHHCCCCCEEEEEECCCCCHHHHHHC
GAIARFSPIMDAVKKFAYAGNPVIGICNGFQILTEAGLLPGALRSNDSLNFICKPQKLVV
CCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCCCCCCCCCEEEEECCCEEEE
ENNQTIFTKRFDLKQTVMFPIAHGEGNYYCDSATLQDLKDHHQIVLRYQNNPNGSTDDIA
ECCCEEEEEECCCCEEEEEEEEECCCCEEECCCHHHHHHCCEEEEEEECCCCCCCHHHHH
GIINQKGNVLGMMPHPERASEAVLGGEDGKMLFQSLIESMTQNV
HHHCCCCCEEEECCCCCCCCHHEECCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA