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The map label for this gene is guaA [H]

Identifier: 116493049

GI number: 116493049

Start: 1293091

End: 1293642

Strand: Reverse

Name: guaA [H]

Synonym: PEPE_1301

Alternate gene names: 116493049

Gene position: 1293642-1293091 (Counterclockwise)

Preceding gene: 116493050

Following gene: 116493043

Centisome position: 70.6

GC content: 34.24

Gene sequence:

>552_bases
ATGAAATTAAAATGTACGTGGTCAACTAAGAATGCAATTTTAGAAAACTATCATGATAAGATATGGGGAAAGCCATGTTT
TAGTGACCAAGAACTCTTTAAATGTCTGGCAATTCAAATTTTCCAATCGGGGTTAGATTTACGAACGGTTTTGACGAAAT
TGGAAGCATTAAATGAAATGTTTGACGAGTTTAAAGTTCAAACTGTTGCTGGCTATGATCAGTCTAAATTAGAAGCGTTG
ATGGCATGTCCATTAATCATTAGAAACCGACGAAAAATTAAAGCAGTTATCCATAACGCAGATGTGATCTTAAAAATGTC
TCAAACGGGGATGTCTTTTAATGATTTTATCTGGTCAAAAGTAGATTTTGTTCCTATGGATTTAGAACCCAAAAATAATG
CTAAGATGATGTTTGATTTACCAATTGCTAGAAGGGTGTGTAAGGACATGCAAGAGCTGGGATTTCAGTTTGTGGGGCCT
ACTAACATTAGCTTCTTTTTACAAGCAAGTGGAATAATTAATACACACTGGGTAAATTGTAGTTATCGTTAA

Upstream 100 bases:

>100_bases
TGAAAGTATCGTATTAGGCAAGCAAAAGCTTTACGATGAATTAAAAAAATAAATTTAAAATCCCTCTTTAGAGTAATTAA
ACCCTAAGGAGGGATTTTTT

Downstream 100 bases:

>100_bases
AATGGCGTAAATAAAAAGTACGGCGATTTAATTTTTTTAAACTAAATTACTGTACTTTATTTTTATTATTTATTTTCTAA
GTCTGTGCGAACAACCAAAA

Product: DNA-3-methyladenine glycosylase I

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKLKCTWSTKNAILENYHDKIWGKPCFSDQELFKCLAIQIFQSGLDLRTVLTKLEALNEMFDEFKVQTVAGYDQSKLEAL
MACPLIIRNRRKIKAVIHNADVILKMSQTGMSFNDFIWSKVDFVPMDLEPKNNAKMMFDLPIARRVCKDMQELGFQFVGP
TNISFFLQASGIINTHWVNCSYR

Sequences:

>Translated_183_residues
MKLKCTWSTKNAILENYHDKIWGKPCFSDQELFKCLAIQIFQSGLDLRTVLTKLEALNEMFDEFKVQTVAGYDQSKLEAL
MACPLIIRNRRKIKAVIHNADVILKMSQTGMSFNDFIWSKVDFVPMDLEPKNNAKMMFDLPIARRVCKDMQELGFQFVGP
TNISFFLQASGIINTHWVNCSYR
>Mature_183_residues
MKLKCTWSTKNAILENYHDKIWGKPCFSDQELFKCLAIQIFQSGLDLRTVLTKLEALNEMFDEFKVQTVAGYDQSKLEAL
MACPLIIRNRRKIKAVIHNADVILKMSQTGMSFNDFIWSKVDFVPMDLEPKNNAKMMFDLPIARRVCKDMQELGFQFVGP
TNISFFLQASGIINTHWVNCSYR

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=177, Percent_Identity=33.8983050847458, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 21171; Mature: 21171

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKCTWSTKNAILENYHDKIWGKPCFSDQELFKCLAIQIFQSGLDLRTVLTKLEALNEM
CEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FDEFKVQTVAGYDQSKLEALMACPLIIRNRRKIKAVIHNADVILKMSQTGMSFNDFIWSK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEEECCCCCCHHHHHHCC
VDFVPMDLEPKNNAKMMFDLPIARRVCKDMQELGFQFVGPTNISFFLQASGIINTHWVNC
CCEEECCCCCCCCCEEEEECHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCEEEEEEEE
SYR
ECC
>Mature Secondary Structure
MKLKCTWSTKNAILENYHDKIWGKPCFSDQELFKCLAIQIFQSGLDLRTVLTKLEALNEM
CEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FDEFKVQTVAGYDQSKLEALMACPLIIRNRRKIKAVIHNADVILKMSQTGMSFNDFIWSK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEEECCCCCCHHHHHHCC
VDFVPMDLEPKNNAKMMFDLPIARRVCKDMQELGFQFVGPTNISFFLQASGIINTHWVNC
CCEEECCCCCCCCCEEEEECHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCEEEEEEEE
SYR
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]