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The map label for this gene is ydgF [H]

Identifier: 116492978

GI number: 116492978

Start: 1219554

End: 1220918

Strand: Reverse

Name: ydgF [H]

Synonym: PEPE_1230

Alternate gene names: 116492978

Gene position: 1220918-1219554 (Counterclockwise)

Preceding gene: 116492979

Following gene: 116492977

Centisome position: 66.63

GC content: 37.29

Gene sequence:

>1365_bases
ATGGAAGAAAATGGTAATAATGAGCTGGCTCGGAATTTAAAGAGCAGGCACGTTCAGTTAATTGCGATTGGAGGAACGAT
TGGAACGGGGCTTTTCCTTGGGGCAGGAAGTTCTATTCATTTAGCAGGACCGTCAATTCTATTAGCATATATTGTAACTG
GATTGGTTTGTTTTTGGCTCATGCGAGCGTTAGGTGAACTACTGTTATCAGATTTAGAATCAACTTCATTTGTAACTTTT
GTAACTAAATATTTAGGAAAAAAAGTAGGATTTGTCACGGGATGGACGTATTGGGTTTGCTGGATAACGATTGCAATGGC
TGAGATTACGGCAACCGGAATGTACGTTAGGTATTGGTTTCCAAGTGTGCCACAATGGATTCCAGGATTTATTATCCTTA
TTTTATTAATCGGGCTAAACTTGATCACGGTTGAGGCTTTTGGAGAGACTGAATTTTGGTTTTCAATTATTAAAATTATT
GCAATAGTGGCTTTGATTGCCATTGGTTTTATTATGGTACTTTTACACTCTAAAACAAACGTAGGACATGCCGACCTTAC
TAATTTAATACATTTTGGCGGTATTTTTCCGCAAGGATTGAAAGGCTTTATCCTTTCTTTTCAAATGGTTTTATTCGCAT
TTGTTGGTATTGAGATGGTAGGGATGACAGCCGCTGAGACTAGAGATCCTAAAAGTGTAATCCCTAAGGCTATTAATGAA
ATACCAGTGCGAATTGGTATCTTTTATGTTGGCGCGCTATTTTTCTTAATGGCAATCTATCCTTGGAATGAAATTAATCC
CAATGGAAGCCCTTTTGTACAAGTCTTTAAGAATATCGGTATCCCAGGAGCAGGTGGAATCATTAACTTTGTGGTCCTAA
CGGCAGCGGCTTCAGCATGTAATAGTTCACTGTTCACAACTGGACGAATGCTATTCTCATTAACCTATGGAAGTTCAAAC
AAACTAGGTAAACGACTAGGTACCTTGTCTAAAAGTCAAGTGCCCAAAAATGCGATTTTGTTATCATCGCTAGTGATTGC
AGTAGCAGTCATTTTAAATATCTTGATGCCAGAAGGAGTATTTACACTAATTTCTAGTATTGCGACAACCTGTTTCTTGT
TTATCTGGGGAACGATTGTCTTAGCTCATTTGAAATATAAAAAAGGTCAAAAGCAGGCTAAAAAAGAATTCAGTATGCCA
TTTTTCCCAATTAGTAATTATATTGTATTAACTTTCCTAAGTTTCGTGGGCGTTGTATTATTATTGCAAAAGGAAACAGC
GATTGCTTTAATTGGATCATTAATTTGGTTCGGTGTAATGTTTACGGTAGCGAAAATTAAGGGAAAAGGGGAGCTAATGG
ATTGA

Upstream 100 bases:

>100_bases
TTATTTTAGGTTTTACTAATTAAAAAGTTTTATGTATCATTAGACTATTAAAAGTCTAATGATTTTTTAATTTTTGAAAC
ATTTCTGGGGGGAATTGATT

Downstream 100 bases:

>100_bases
AATTTTTCACCTCGGATACACACTTTTTTCATAAAGAATTGTTAAAAGATAAAGACTTTGCTCCACGCGATTTTGACAAT
ATCGAAGATATGCATGCAGC

Product: gamma-aminobutyrate permease related permease

Products: D-glycine [Cytoplasm]; D-alanine [Cytoplasm]; Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MEENGNNELARNLKSRHVQLIAIGGTIGTGLFLGAGSSIHLAGPSILLAYIVTGLVCFWLMRALGELLLSDLESTSFVTF
VTKYLGKKVGFVTGWTYWVCWITIAMAEITATGMYVRYWFPSVPQWIPGFIILILLIGLNLITVEAFGETEFWFSIIKII
AIVALIAIGFIMVLLHSKTNVGHADLTNLIHFGGIFPQGLKGFILSFQMVLFAFVGIEMVGMTAAETRDPKSVIPKAINE
IPVRIGIFYVGALFFLMAIYPWNEINPNGSPFVQVFKNIGIPGAGGIINFVVLTAAASACNSSLFTTGRMLFSLTYGSSN
KLGKRLGTLSKSQVPKNAILLSSLVIAVAVILNILMPEGVFTLISSIATTCFLFIWGTIVLAHLKYKKGQKQAKKEFSMP
FFPISNYIVLTFLSFVGVVLLLQKETAIALIGSLIWFGVMFTVAKIKGKGELMD

Sequences:

>Translated_454_residues
MEENGNNELARNLKSRHVQLIAIGGTIGTGLFLGAGSSIHLAGPSILLAYIVTGLVCFWLMRALGELLLSDLESTSFVTF
VTKYLGKKVGFVTGWTYWVCWITIAMAEITATGMYVRYWFPSVPQWIPGFIILILLIGLNLITVEAFGETEFWFSIIKII
AIVALIAIGFIMVLLHSKTNVGHADLTNLIHFGGIFPQGLKGFILSFQMVLFAFVGIEMVGMTAAETRDPKSVIPKAINE
IPVRIGIFYVGALFFLMAIYPWNEINPNGSPFVQVFKNIGIPGAGGIINFVVLTAAASACNSSLFTTGRMLFSLTYGSSN
KLGKRLGTLSKSQVPKNAILLSSLVIAVAVILNILMPEGVFTLISSIATTCFLFIWGTIVLAHLKYKKGQKQAKKEFSMP
FFPISNYIVLTFLSFVGVVLLLQKETAIALIGSLIWFGVMFTVAKIKGKGELMD
>Mature_454_residues
MEENGNNELARNLKSRHVQLIAIGGTIGTGLFLGAGSSIHLAGPSILLAYIVTGLVCFWLMRALGELLLSDLESTSFVTF
VTKYLGKKVGFVTGWTYWVCWITIAMAEITATGMYVRYWFPSVPQWIPGFIILILLIGLNLITVEAFGETEFWFSIIKII
AIVALIAIGFIMVLLHSKTNVGHADLTNLIHFGGIFPQGLKGFILSFQMVLFAFVGIEMVGMTAAETRDPKSVIPKAINE
IPVRIGIFYVGALFFLMAIYPWNEINPNGSPFVQVFKNIGIPGAGGIINFVVLTAAASACNSSLFTTGRMLFSLTYGSSN
KLGKRLGTLSKSQVPKNAILLSSLVIAVAVILNILMPEGVFTLISSIATTCFLFIWGTIVLAHLKYKKGQKQAKKEFSMP
FFPISNYIVLTFLSFVGVVLLLQKETAIALIGSLIWFGVMFTVAKIKGKGELMD

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1790653, Length=441, Percent_Identity=44.671201814059, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1786789, Length=450, Percent_Identity=40, Blast_Score=355, Evalue=3e-99,
Organism=Escherichia coli, GI1786302, Length=440, Percent_Identity=39.7727272727273, Blast_Score=344, Evalue=6e-96,
Organism=Escherichia coli, GI48994972, Length=452, Percent_Identity=38.0530973451327, Blast_Score=328, Evalue=5e-91,
Organism=Escherichia coli, GI1786602, Length=441, Percent_Identity=39.0022675736961, Blast_Score=304, Evalue=8e-84,
Organism=Escherichia coli, GI87081915, Length=466, Percent_Identity=37.5536480686695, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI87081708, Length=414, Percent_Identity=35.5072463768116, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI1789017, Length=448, Percent_Identity=31.6964285714286, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI1788480, Length=410, Percent_Identity=32.6829268292683, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI87081869, Length=199, Percent_Identity=28.1407035175879, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320772, Length=450, Percent_Identity=30.8888888888889, Blast_Score=187, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6324924, Length=423, Percent_Identity=34.0425531914894, Blast_Score=187, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6324061, Length=440, Percent_Identity=29.3181818181818, Blast_Score=177, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6322892, Length=396, Percent_Identity=29.5454545454545, Blast_Score=170, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6324990, Length=411, Percent_Identity=29.9270072992701, Blast_Score=169, Evalue=9e-43,
Organism=Saccharomyces cerevisiae, GI6321629, Length=419, Percent_Identity=27.2076372315036, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6324059, Length=449, Percent_Identity=30.7349665924276, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320717, Length=404, Percent_Identity=26.4851485148515, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6320251, Length=409, Percent_Identity=27.6283618581907, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6319824, Length=409, Percent_Identity=26.4058679706601, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6324553, Length=421, Percent_Identity=28.5035629453682, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6319543, Length=415, Percent_Identity=27.710843373494, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321053, Length=415, Percent_Identity=25.3012048192771, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319542, Length=400, Percent_Identity=26.25, Blast_Score=136, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6322967, Length=409, Percent_Identity=26.6503667481663, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6319608, Length=335, Percent_Identity=27.4626865671642, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324981, Length=401, Percent_Identity=28.1795511221945, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320364, Length=548, Percent_Identity=23.5401459854015, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24668806, Length=376, Percent_Identity=21.5425531914894, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356285, Length=376, Percent_Identity=21.5425531914894, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24668802, Length=376, Percent_Identity=21.5425531914894, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49539; Mature: 49539

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEENGNNELARNLKSRHVQLIAIGGTIGTGLFLGAGSSIHLAGPSILLAYIVTGLVCFWL
CCCCCCHHHHHHHHHCCEEEEEECCCHHHHHHEECCCEEEECCHHHHHHHHHHHHHHHHH
MRALGELLLSDLESTSFVTFVTKYLGKKVGFVTGWTYWVCWITIAMAEITATGMYVRYWF
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
PSVPQWIPGFIILILLIGLNLITVEAFGETEFWFSIIKIIAIVALIAIGFIMVLLHSKTN
CCCCHHHHHHHHHHHHHCCHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VGHADLTNLIHFGGIFPQGLKGFILSFQMVLFAFVGIEMVGMTAAETRDPKSVIPKAINE
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHH
IPVRIGIFYVGALFFLMAIYPWNEINPNGSPFVQVFKNIGIPGAGGIINFVVLTAAASAC
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
NSSLFTTGRMLFSLTYGSSNKLGKRLGTLSKSQVPKNAILLSSLVIAVAVILNILMPEGV
CCHHHHHHHHHEEEECCCCHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCHH
FTLISSIATTCFLFIWGTIVLAHLKYKKGQKQAKKEFSMPFFPISNYIVLTFLSFVGVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LLQKETAIALIGSLIWFGVMFTVAKIKGKGELMD
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEENGNNELARNLKSRHVQLIAIGGTIGTGLFLGAGSSIHLAGPSILLAYIVTGLVCFWL
CCCCCCHHHHHHHHHCCEEEEEECCCHHHHHHEECCCEEEECCHHHHHHHHHHHHHHHHH
MRALGELLLSDLESTSFVTFVTKYLGKKVGFVTGWTYWVCWITIAMAEITATGMYVRYWF
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
PSVPQWIPGFIILILLIGLNLITVEAFGETEFWFSIIKIIAIVALIAIGFIMVLLHSKTN
CCCCHHHHHHHHHHHHHCCHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VGHADLTNLIHFGGIFPQGLKGFILSFQMVLFAFVGIEMVGMTAAETRDPKSVIPKAINE
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHH
IPVRIGIFYVGALFFLMAIYPWNEINPNGSPFVQVFKNIGIPGAGGIINFVVLTAAASAC
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
NSSLFTTGRMLFSLTYGSSNKLGKRLGTLSKSQVPKNAILLSSLVIAVAVILNILMPEGV
CCHHHHHHHHHEEEECCCCHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCHH
FTLISSIATTCFLFIWGTIVLAHLKYKKGQKQAKKEFSMPFFPISNYIVLTFLSFVGVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LLQKETAIALIGSLIWFGVMFTVAKIKGKGELMD
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glycine [Periplasm]; D-alanine [Periplasm]; Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-glycine [Periplasm] = Proton [Cytoplasm] + D-glycine [Cytoplasm] Proton [Periplasm] + D-alanine [Periplasm] = Proton [Cytoplasm] + D-alanine [Cytoplasm] Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cyto

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]