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The map label for this gene is ytxK [H]

Identifier: 116492979

GI number: 116492979

Start: 1221010

End: 1222014

Strand: Reverse

Name: ytxK [H]

Synonym: PEPE_1231

Alternate gene names: 116492979

Gene position: 1222014-1221010 (Counterclockwise)

Preceding gene: 116492980

Following gene: 116492978

Centisome position: 66.69

GC content: 32.54

Gene sequence:

>1005_bases
ATGAATACAGAAACTATTAAAAAGATTTATAAAACATTCGAGAAATCAATTGAAATTTTAAAAGAGGAATTGGACGTTGA
TTTTCTAGATGCATTTATTGAAACAGGTGACAATCTAATTTCTGGTCAAATTCATGTTGAAGACGGGAAGCCTAGCGAAG
CAATTATTGGCGAATTAAAAAAAATATATGAAGGTTTTAAGTACAATGATTATAGCCCGGAAGAATTACGAAAAGCTATC
CAATTGGTTATGATTCGTGCTAACAAAGAAGAACGAATTCAAGCAAATCATCAATTTACACCGGAAGCAGTTGGAATGCT
TTTTAACTACATTATTGAAAATTTAAAAGTTGATTCAAATCAATTAACAATTTTTGATCCCGCTGTAGGTACAGGTAATC
TACTATCAACAATTTTAAATTATTTTCAAACTAAACGAATTAATTTTAAAGGAATTGGTGTAGATAATGATGATACGATG
CTTTCGATTGCTAGCATGTCATTTACTTTTGAAAGACTAGAGGTGGAGCTCTTCCATCAAGACAGTATTGATGATTTATT
TGTAAAGAATGTTGATATTGCGGTATCTGATTTGCCGGTTGGCTATTATCCTATTGACGAACGGACTAAGGGCTTTGAAA
CGAGAAGCAAGGAGGGACATTCTTTTGTACACCATTTATTAATTGAGCAATCAATGAAGACTATCCGACCGGGAGGGTAT
GGGGTTTTCCTAGTTCCAAGTAATTTATTTCAAACTCAAGAGGCTAAAAAATTATTATCATTTTTCCACGAAAAAGTTTA
TTTGCAAGCAATTTTGAATCTGCCTACCAAAATGTTTAAAGATGAACAGGCGCAGAAGTCAATTCTCATTTTGCAAAAGG
TTGGAGCTAGTGCTAAACAGGCAGAACAAGTTTTATTAGGAGAATTCCCAGAATTCAATAATCAAGAAAAAATGCTTGAT
TTCTTACAAGATTTTAAGAAATGGGCTCAAAAGAACTTATTTTAG

Upstream 100 bases:

>100_bases
AAATAAATGATGATAATAACTTGACTATAAAAGTCCTAAAAGGTAATACTGTAAAGGTTGAATTTAATGAAAGTGGCTAT
TAGTGAAGAGGAGTTTATAA

Downstream 100 bases:

>100_bases
GTTTTACTAATTAAAAAGTTTTATGTATCATTAGACTATTAAAAGTCTAATGATTTTTTAATTTTTGAAACATTTCTGGG
GGGAATTGATTATGGAAGAA

Product: adenine-specific DNA methylase

Products: S-Adenosyl-L-Homocysteine; DNA 6-Methylaminopurine. [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MNTETIKKIYKTFEKSIEILKEELDVDFLDAFIETGDNLISGQIHVEDGKPSEAIIGELKKIYEGFKYNDYSPEELRKAI
QLVMIRANKEERIQANHQFTPEAVGMLFNYIIENLKVDSNQLTIFDPAVGTGNLLSTILNYFQTKRINFKGIGVDNDDTM
LSIASMSFTFERLEVELFHQDSIDDLFVKNVDIAVSDLPVGYYPIDERTKGFETRSKEGHSFVHHLLIEQSMKTIRPGGY
GVFLVPSNLFQTQEAKKLLSFFHEKVYLQAILNLPTKMFKDEQAQKSILILQKVGASAKQAEQVLLGEFPEFNNQEKMLD
FLQDFKKWAQKNLF

Sequences:

>Translated_334_residues
MNTETIKKIYKTFEKSIEILKEELDVDFLDAFIETGDNLISGQIHVEDGKPSEAIIGELKKIYEGFKYNDYSPEELRKAI
QLVMIRANKEERIQANHQFTPEAVGMLFNYIIENLKVDSNQLTIFDPAVGTGNLLSTILNYFQTKRINFKGIGVDNDDTM
LSIASMSFTFERLEVELFHQDSIDDLFVKNVDIAVSDLPVGYYPIDERTKGFETRSKEGHSFVHHLLIEQSMKTIRPGGY
GVFLVPSNLFQTQEAKKLLSFFHEKVYLQAILNLPTKMFKDEQAQKSILILQKVGASAKQAEQVLLGEFPEFNNQEKMLD
FLQDFKKWAQKNLF
>Mature_334_residues
MNTETIKKIYKTFEKSIEILKEELDVDFLDAFIETGDNLISGQIHVEDGKPSEAIIGELKKIYEGFKYNDYSPEELRKAI
QLVMIRANKEERIQANHQFTPEAVGMLFNYIIENLKVDSNQLTIFDPAVGTGNLLSTILNYFQTKRINFKGIGVDNDDTM
LSIASMSFTFERLEVELFHQDSIDDLFVKNVDIAVSDLPVGYYPIDERTKGFETRSKEGHSFVHHLLIEQSMKTIRPGGY
GVFLVPSNLFQTQEAKKLLSFFHEKVYLQAILNLPTKMFKDEQAQKSILILQKVGASAKQAEQVLLGEFPEFNNQEKMLD
FLQDFKKWAQKNLF

Specific function: The M And S Subunits Together Form A Methyltransferase (Mtase) That Methylates Two Adenine Residues In Complementary Strands Of A Bipartite DNA Recognition Sequence. In The Presence Of The R Subunit The Complex Can Also Act As An Endonuclease, Binding To

COG id: COG0827

COG function: function code L; Adenine-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To type I restriction system adenine methylases [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296
- InterPro:   IPR016843 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: 2.1.1.72 [C]

Molecular weight: Translated: 38404; Mature: 38404

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTETIKKIYKTFEKSIEILKEELDVDFLDAFIETGDNLISGQIHVEDGKPSEAIIGELK
CCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEECEEEECCCCCHHHHHHHHH
KIYEGFKYNDYSPEELRKAIQLVMIRANKEERIQANHQFTPEAVGMLFNYIIENLKVDSN
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
QLTIFDPAVGTGNLLSTILNYFQTKRINFKGIGVDNDDTMLSIASMSFTFERLEVELFHQ
CEEEECCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEHHHHHHHHHHHHEEECCC
DSIDDLFVKNVDIAVSDLPVGYYPIDERTKGFETRSKEGHSFVHHLLIEQSMKTIRPGGY
CCCHHHHHHCCCEEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
GVFLVPSNLFQTQEAKKLLSFFHEKVYLQAILNLPTKMFKDEQAQKSILILQKVGASAKQ
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCHHH
AEQVLLGEFPEFNNQEKMLDFLQDFKKWAQKNLF
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTETIKKIYKTFEKSIEILKEELDVDFLDAFIETGDNLISGQIHVEDGKPSEAIIGELK
CCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEECEEEECCCCCHHHHHHHHH
KIYEGFKYNDYSPEELRKAIQLVMIRANKEERIQANHQFTPEAVGMLFNYIIENLKVDSN
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
QLTIFDPAVGTGNLLSTILNYFQTKRINFKGIGVDNDDTMLSIASMSFTFERLEVELFHQ
CEEEECCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEHHHHHHHHHHHHEEECCC
DSIDDLFVKNVDIAVSDLPVGYYPIDERTKGFETRSKEGHSFVHHLLIEQSMKTIRPGGY
CCCHHHHHHCCCEEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
GVFLVPSNLFQTQEAKKLLSFFHEKVYLQAILNLPTKMFKDEQAQKSILILQKVGASAKQ
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCHHH
AEQVLLGEFPEFNNQEKMLDFLQDFKKWAQKNLF
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; DNA Adenine; DNA [C]

Specific reaction: S-Adenosyl-L-Methionine + DNA Adenine = S-Adenosyl-L-Homocysteine + DNA 6-Methylaminopurine. Protein + DNA = Protein-DNA [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 8226682 [H]