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The map label for this gene is agaC [H]

Identifier: 116491986

GI number: 116491986

Start: 205015

End: 205695

Strand: Direct

Name: agaC [H]

Synonym: PEPE_0172

Alternate gene names: 116491986

Gene position: 205015-205695 (Clockwise)

Preceding gene: 116491985

Following gene: 116491987

Centisome position: 11.19

GC content: 38.03

Gene sequence:

>681_bases
TTGGGCGATCCTACATTGGGTATCATGGCTGGTGGACTTACTGAACTAACTTTTGCGGGATTGACTCCAGCTGGTGGGAC
ACAACCACCTAACCCAGCAGTGTGCGGGATAATGACTGTAGTTATTGCGCATACTGCAAGTGTAGGACCATCTACGGCTA
TTGGTTTATCATTACCATTCGCAATGTTAATGCAATATATTTTATTGATGTGCTATTCATTATTTTCAGTATTCATGCCA
GTTATGGATAAAGCAGCAGCCGAAGGAAATACCAAGAAATTTGCTTCTGTACCATATTTAATTATGGCAATTGTAGGAGT
TTTATTCTTTGTAGTAATTTTCTTATCAGCCTATGCTGCTCAAGGACCTATGCAAGCTCTAGTTAAAGCAATGCCTGTTT
GGTTAATACATGGTTTTGAACTAGCAGGAAGTGCATTACCTGCGGTTGGTTTTGCAATGTTACTAAAAGTTCTTTTACGG
GTCGAATATGTACCGTATTTATTACTTGGGTTTGTGGTAGCAAGTTTCATTAACTTCTCAAACGTATTGCCAGCAGCTGT
AATTGGTATTGTATTTGCTATTATTGAGTTCTTTAGAGATAAAAAGAATAAACAATTACAAGAACAAATTGAAGCTCTTA
AGGAAGCTGGTATAAATGGAGGCGAAGAAGATGGCATCTAA

Upstream 100 bases:

>100_bases
AATGTTATCAATATTTGCTGTGATAGCAGGTCTTGATTCATGGCTAGAAGTTTTATACATATTTAGACCTATCATAAGTT
GTACTGTAGCAGGTTTTATC

Downstream 100 bases:

>100_bases
CGTAGAAAATACTAAGAAAACAAGCAAGTTAAGCAAAAAAGATATTACTATGCTAGGAATTCGCTCTTCATTATTACAAT
CTGCTTTTTCTTATGAACGA

Product: N-acetylgalactosamine PTS, EIIC

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Aga; PTS system N-acetylgalactosamine-specific EIIC component 1 [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MGDPTLGIMAGGLTELTFAGLTPAGGTQPPNPAVCGIMTVVIAHTASVGPSTAIGLSLPFAMLMQYILLMCYSLFSVFMP
VMDKAAAEGNTKKFASVPYLIMAIVGVLFFVVIFLSAYAAQGPMQALVKAMPVWLIHGFELAGSALPAVGFAMLLKVLLR
VEYVPYLLLGFVVASFINFSNVLPAAVIGIVFAIIEFFRDKKNKQLQEQIEALKEAGINGGEEDGI

Sequences:

>Translated_226_residues
MGDPTLGIMAGGLTELTFAGLTPAGGTQPPNPAVCGIMTVVIAHTASVGPSTAIGLSLPFAMLMQYILLMCYSLFSVFMP
VMDKAAAEGNTKKFASVPYLIMAIVGVLFFVVIFLSAYAAQGPMQALVKAMPVWLIHGFELAGSALPAVGFAMLLKVLLR
VEYVPYLLLGFVVASFINFSNVLPAAVIGIVFAIIEFFRDKKNKQLQEQIEALKEAGINGGEEDGI
>Mature_225_residues
GDPTLGIMAGGLTELTFAGLTPAGGTQPPNPAVCGIMTVVIAHTASVGPSTAIGLSLPFAMLMQYILLMCYSLFSVFMPV
MDKAAAEGNTKKFASVPYLIMAIVGVLFFVVIFLSAYAAQGPMQALVKAMPVWLIHGFELAGSALPAVGFAMLLKVLLRV
EYVPYLLLGFVVASFINFSNVLPAAVIGIVFAIIEFFRDKKNKQLQEQIEALKEAGINGGEEDGI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3715

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1789528, Length=224, Percent_Identity=53.125, Blast_Score=234, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004700
- InterPro:   IPR018404 [H]

Pfam domain/function: PF03609 EII-Sor [H]

EC number: 2.7.1.69

Molecular weight: Translated: 23938; Mature: 23807

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS51106 PTS_EIIC_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDPTLGIMAGGLTELTFAGLTPAGGTQPPNPAVCGIMTVVIAHTASVGPSTAIGLSLPF
CCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AMLMQYILLMCYSLFSVFMPVMDKAAAEGNTKKFASVPYLIMAIVGVLFFVVIFLSAYAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QGPMQALVKAMPVWLIHGFELAGSALPAVGFAMLLKVLLRVEYVPYLLLGFVVASFINFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVLPAAVIGIVFAIIEFFRDKKNKQLQEQIEALKEAGINGGEEDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
GDPTLGIMAGGLTELTFAGLTPAGGTQPPNPAVCGIMTVVIAHTASVGPSTAIGLSLPF
CCCCHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AMLMQYILLMCYSLFSVFMPVMDKAAAEGNTKKFASVPYLIMAIVGVLFFVVIFLSAYAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QGPMQALVKAMPVWLIHGFELAGSALPAVGFAMLLKVLLRVEYVPYLLLGFVVASFINFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVLPAAVIGIVFAIIEFFRDKKNKQLQEQIEALKEAGINGGEEDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503; 8932697 [H]