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The map label for this gene is yegS [C]

Identifier: 116491865

GI number: 116491865

Start: 43989

End: 44879

Strand: Reverse

Name: yegS [C]

Synonym: PEPE_0047

Alternate gene names: 116491865

Gene position: 44879-43989 (Counterclockwise)

Preceding gene: 116491866

Following gene: 116491860

Centisome position: 2.45

GC content: 41.08

Gene sequence:

>891_bases
ATGCCTAAATATACCGTTATTTATAATGAAGATGCTGGAAAAAATGATAATAAATCCATCGCTGAACGCTTTCAGCAAGC
GGCTGAACGATTGAAGCGATCAACCACCTTAAAGGCCACGTCTAGTCGTCAAGAAGCGCTCGATTATGTAGTTGATCATA
TTGATCAACTGGATACAGTTATTACGATTGGAGGAGATGGCTCCATTAATACCGTGTTTTCAGCCTTCCTTAAGGCTAAA
AAATCAGTCGAAGTGGGAATTATTCCTGGTGGTACCGTCAATAATTTTGCTAAAGCACTCGAAATTCCTCAAGATGAAGA
AGCCGCTTTTGATACCATTCTTAATGGTCATCCCCTCGCTGTGGATTTGGCCCATACTGAAGACCGTGCCATCATTAGTA
GCCTTACACTTGGAACCCTTGCTGATATGGCCCGCCATGTCGGACAAGATGAAAAGAAAAAATGGGGACCTTTAATTTAT
TTGAGTAAAGGAATTCGCCAGTTAATTGCTAAGAAATCTTACCAGATTAAAGTTAGTACTGCGGATGGCGACCATGTCTA
TCGCACGCGCTTCCTATTAGCAACCACTACCAACTCAGTGGGTGGTTTTACTAATTTTGATACATCTGCATCTCCAGCAG
ATGGAAAAATTCACTTGGTTATCCTGAAACATTTTTCATTCATGCGTCTTTTAGGTTACCTAAGTTATTTCCTAACTGGA
CGTTTTCGAGATATCAAAGATGTTGATCAACTTACCGCTCAGGAAGTTGAAATTTCTGCCGTTGATTCACACTTGAAGGT
TGAAACTCGAATTGATGGTGATCCTAGTGACCAACTCCCCATCAAACTGGGCGTAGAGCAAGGCTTCGTTCAAGTTATGG
TACCTAAATAA

Upstream 100 bases:

>100_bases
GCGAACACACTCATTTGGAGTAAAAATCGAAATTTACCCAATTTAAATCGATTATTTTTAGATACTTTACAAAAAAATTT
AGCTCAACAAGGAGGCTCTG

Downstream 100 bases:

>100_bases
TTTAACTCAAAATAAAATGGACCAACGCAATCAAAGCGTTGATCCATTTTTTATATTATCGAACCACAGTTACCGTGATA
GGAGCATACTTCGCCATGTA

Product: diacylglycerol kinase family lipid kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPKYTVIYNEDAGKNDNKSIAERFQQAAERLKRSTTLKATSSRQEALDYVVDHIDQLDTVITIGGDGSINTVFSAFLKAK
KSVEVGIIPGGTVNNFAKALEIPQDEEAAFDTILNGHPLAVDLAHTEDRAIISSLTLGTLADMARHVGQDEKKKWGPLIY
LSKGIRQLIAKKSYQIKVSTADGDHVYRTRFLLATTTNSVGGFTNFDTSASPADGKIHLVILKHFSFMRLLGYLSYFLTG
RFRDIKDVDQLTAQEVEISAVDSHLKVETRIDGDPSDQLPIKLGVEQGFVQVMVPK

Sequences:

>Translated_296_residues
MPKYTVIYNEDAGKNDNKSIAERFQQAAERLKRSTTLKATSSRQEALDYVVDHIDQLDTVITIGGDGSINTVFSAFLKAK
KSVEVGIIPGGTVNNFAKALEIPQDEEAAFDTILNGHPLAVDLAHTEDRAIISSLTLGTLADMARHVGQDEKKKWGPLIY
LSKGIRQLIAKKSYQIKVSTADGDHVYRTRFLLATTTNSVGGFTNFDTSASPADGKIHLVILKHFSFMRLLGYLSYFLTG
RFRDIKDVDQLTAQEVEISAVDSHLKVETRIDGDPSDQLPIKLGVEQGFVQVMVPK
>Mature_295_residues
PKYTVIYNEDAGKNDNKSIAERFQQAAERLKRSTTLKATSSRQEALDYVVDHIDQLDTVITIGGDGSINTVFSAFLKAKK
SVEVGIIPGGTVNNFAKALEIPQDEEAAFDTILNGHPLAVDLAHTEDRAIISSLTLGTLADMARHVGQDEKKKWGPLIYL
SKGIRQLIAKKSYQIKVSTADGDHVYRTRFLLATTTNSVGGFTNFDTSASPADGKIHLVILKHFSFMRLLGYLSYFLTGR
FRDIKDVDQLTAQEVEISAVDSHLKVETRIDGDPSDQLPIKLGVEQGFVQVMVPK

Specific function: May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact, is not able to exhibit diacylglycerol kinase activity in vitro [H]

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017438
- InterPro:   IPR005218
- InterPro:   IPR001206 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: NA

Molecular weight: Translated: 32627; Mature: 32496

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKYTVIYNEDAGKNDNKSIAERFQQAAERLKRSTTLKATSSRQEALDYVVDHIDQLDTV
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCEECCCCHHHHHHHHHHHHHCCCEE
ITIGGDGSINTVFSAFLKAKKSVEVGIIPGGTVNNFAKALEIPQDEEAAFDTILNGHPLA
EEECCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHCCCCCEE
VDLAHTEDRAIISSLTLGTLADMARHVGQDEKKKWGPLIYLSKGIRQLIAKKSYQIKVST
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEHHHHHHHHHHCCCEEEEEEE
ADGDHVYRTRFLLATTTNSVGGFTNFDTSASPADGKIHLVILKHFSFMRLLGYLSYFLTG
CCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHC
RFRDIKDVDQLTAQEVEISAVDSHLKVETRIDGDPSDQLPIKLGVEQGFVQVMVPK
CCCCHHHHHHHHHHHEEEEECCCCEEEEEEECCCCCCCCCEEEECCCCEEEEEECC
>Mature Secondary Structure 
PKYTVIYNEDAGKNDNKSIAERFQQAAERLKRSTTLKATSSRQEALDYVVDHIDQLDTV
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCEECCCCHHHHHHHHHHHHHCCCEE
ITIGGDGSINTVFSAFLKAKKSVEVGIIPGGTVNNFAKALEIPQDEEAAFDTILNGHPLA
EEECCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHCCCCCEE
VDLAHTEDRAIISSLTLGTLADMARHVGQDEKKKWGPLIYLSKGIRQLIAKKSYQIKVST
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEHHHHHHHHHHCCCEEEEEEE
ADGDHVYRTRFLLATTTNSVGGFTNFDTSASPADGKIHLVILKHFSFMRLLGYLSYFLTG
CCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHC
RFRDIKDVDQLTAQEVEISAVDSHLKVETRIDGDPSDQLPIKLGVEQGFVQVMVPK
CCCCHHHHHHHHHHHEEEEECCCCEEEEEEECCCCCCCCCEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]