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The map label for this gene is czrA [H]

Identifier: 116491846

GI number: 116491846

Start: 27600

End: 27935

Strand: Reverse

Name: czrA [H]

Synonym: PEPE_0028

Alternate gene names: 116491846

Gene position: 27935-27600 (Counterclockwise)

Preceding gene: 116491852

Following gene: 116491842

Centisome position: 1.52

GC content: 36.61

Gene sequence:

>336_bases
ATGAAGCAAAAAAATATAAAATTAATTGACGATGTGATGCTCGCTGAGACCCAAAAAATTCTTAGCTTGCTTAAAAACCC
GGTGCGACTTCAAATTTTATACATTCTGTCGCAGCAGAGCCTCAGTGTTTCTGAAATTGTAGAACTTCTCCATCTCGATC
AGTCGTTGGTCTCTCACCATCTATCAGATTTGCGTAAATACCAGTTAGTTTCAACTAAACGTGATGGTAAATCGATTTTT
TATGAACTCGATGATCCGCATATCTTAGATATTGTTAATGAAACTCTTGAACATGCTGATCACGTGCTAAAGGGGAAAAA
GCACAATGAAAAATAG

Upstream 100 bases:

>100_bases
TATGCAGTTACACCTGTTAAAATATCTTTTATCATCGCTTTTCCTCCCCAACCTTATTTTACATACATATGATAACATAT
TCATATGAAAGGAAGTTAAT

Downstream 100 bases:

>100_bases
CCTAACCCACGGAATTTCCGTCTGGTTAGGCTATTTTTATTTGCATAATTTAGTTTAAGTTAGTTAGTAAAACGCTCTAA
AAAATCTAAATATGAATCAA

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 111; Mature: 111

Protein sequence:

>111_residues
MKQKNIKLIDDVMLAETQKILSLLKNPVRLQILYILSQQSLSVSEIVELLHLDQSLVSHHLSDLRKYQLVSTKRDGKSIF
YELDDPHILDIVNETLEHADHVLKGKKHNEK

Sequences:

>Translated_111_residues
MKQKNIKLIDDVMLAETQKILSLLKNPVRLQILYILSQQSLSVSEIVELLHLDQSLVSHHLSDLRKYQLVSTKRDGKSIF
YELDDPHILDIVNETLEHADHVLKGKKHNEK
>Mature_111_residues
MKQKNIKLIDDVMLAETQKILSLLKNPVRLQILYILSQQSLSVSEIVELLHLDQSLVSHHLSDLRKYQLVSTKRDGKSIF
YELDDPHILDIVNETLEHADHVLKGKKHNEK

Specific function: Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12876; Mature: 12876

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKNIKLIDDVMLAETQKILSLLKNPVRLQILYILSQQSLSVSEIVELLHLDQSLVSHH
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LSDLRKYQLVSTKRDGKSIFYELDDPHILDIVNETLEHADHVLKGKKHNEK
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKQKNIKLIDDVMLAETQKILSLLKNPVRLQILYILSQQSLSVSEIVELLHLDQSLVSHH
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LSDLRKYQLVSTKRDGKSIFYELDDPHILDIVNETLEHADHVLKGKKHNEK
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]