BacMap

Definition	Pediococcus pentosaceus ATCC 25745, complete genome.
Accession	NC_008525
Length	1,832,387

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The map label for this gene is yvaG [H]

Identifier: 116491844

GI number: 116491844

Start: 26103

End: 26897

Strand: Direct

Name: yvaG [H]

Synonym: PEPE_0026

Alternate gene names: 116491844

Gene position: 26103-26897 (Clockwise)

Preceding gene: 116491843

Following gene: 116491845

Centisome position: 1.42

GC content: 40.38

Gene sequence:

>795_bases
ATGGATTTACATTTAACACATAAATTAGCTTTGATTACCGGCTCAACTAAAGGGATTGGGAAAGCCATTGCTACAGAATT
AGCCCGTGAGGGGGCTGACGTAATCATTAACGGACGGAATCAAGATGAGGTTGATCAAGTCGTGGCTGATATTAAAACCC
AATTTCCAAATACTAATCCGCAAGGTGCAGCTGCTGATATTGCCAATGAAGCTAGTCGAACACACCTCTTTGAGCAGTAT
CCCAAGGTTGATATCTTAATCAATAACATGGGAATCTTTCAACCGATGGAATATGCCGATATTGATGATGCTACATGGAA
TAAATTTTTCCAGATTAACGTATTAGCTGGGAATGCTTTAGCTAAATTTTACTTGCCTAAAATGTTAGATCAGGATTTTG
GAAGGATCATTTTTATTGCTAGCGAAGAAGCCGTGATGCCATCGGGAGAAATGCCTCAATACAGCATGACTAAGACCATG
AATTTGTCGTTAGCTAAGAGCTTATCGAAACTAACGGTTGCTACACATGTGACGGTTAATACCATAATGCCAGGTTCGAC
ATTAACTGAAGGGGTACAGCAAATGCTAGAAGATATGTACGCTGATAGTGATTTGCCTAAATCAGAATGGGAAGCGGACT
TTATGAAAAACCATCGTTCCCGTTCTCAAATTCAACGTTTGATTCGTCCGGAAGAAATTGGCCGTTTTGCAGCCTTTGTT
GCTAGTCCAGATGCATCGTCATTTTCTGGTGAAGCATTGCGGATTGATGGTGGATTAGTGCCAACTATTTTTTAA

Upstream 100 bases:

>100_bases
CACCGGAAGATATGGACCAAATTAATGCTTTGAATGAAAACTTGCGCGTCGGACCTAACCCAGATGAATTTGATTTTTAG
ATTTTAGAAGGAGGTAAACT

Downstream 100 bases:

>100_bases
AACGCCAACGCATATCATTATCAATTAACCACTAATTTCTCTATACTGTAGTTAAGGTATTGTTAACGCTTTAAATACGA
CAAGGAGGAATTTTATGGCA

Product: Short-chain alcohol dehydrogenase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MDLHLTHKLALITGSTKGIGKAIATELAREGADVIINGRNQDEVDQVVADIKTQFPNTNPQGAAADIANEASRTHLFEQY
PKVDILINNMGIFQPMEYADIDDATWNKFFQINVLAGNALAKFYLPKMLDQDFGRIIFIASEEAVMPSGEMPQYSMTKTM
NLSLAKSLSKLTVATHVTVNTIMPGSTLTEGVQQMLEDMYADSDLPKSEWEADFMKNHRSRSQIQRLIRPEEIGRFAAFV
ASPDASSFSGEALRIDGGLVPTIF

Sequences:

>Translated_264_residues
MDLHLTHKLALITGSTKGIGKAIATELAREGADVIINGRNQDEVDQVVADIKTQFPNTNPQGAAADIANEASRTHLFEQY
PKVDILINNMGIFQPMEYADIDDATWNKFFQINVLAGNALAKFYLPKMLDQDFGRIIFIASEEAVMPSGEMPQYSMTKTM
NLSLAKSLSKLTVATHVTVNTIMPGSTLTEGVQQMLEDMYADSDLPKSEWEADFMKNHRSRSQIQRLIRPEEIGRFAAFV
ASPDASSFSGEALRIDGGLVPTIF
>Mature_264_residues
MDLHLTHKLALITGSTKGIGKAIATELAREGADVIINGRNQDEVDQVVADIKTQFPNTNPQGAAADIANEASRTHLFEQY
PKVDILINNMGIFQPMEYADIDDATWNKFFQINVLAGNALAKFYLPKMLDQDFGRIIFIASEEAVMPSGEMPQYSMTKTM
NLSLAKSLSKLTVATHVTVNTIMPGSTLTEGVQQMLEDMYADSDLPKSEWEADFMKNHRSRSQIQRLIRPEEIGRFAAFV
ASPDASSFSGEALRIDGGLVPTIF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=260, Percent_Identity=29.6153846153846, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI5031737, Length=259, Percent_Identity=29.3436293436293, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI126723750, Length=266, Percent_Identity=29.6992481203008, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI33667109, Length=187, Percent_Identity=31.0160427807487, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=31.5217391304348, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI7705855, Length=184, Percent_Identity=32.0652173913043, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4504505, Length=208, Percent_Identity=26.4423076923077, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=23.8636363636364, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=26.171875, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI31542939, Length=192, Percent_Identity=28.125, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI109715829, Length=250, Percent_Identity=27.6, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI226371731, Length=183, Percent_Identity=26.2295081967213, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI224922801, Length=163, Percent_Identity=29.4478527607362, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI10190746, Length=221, Percent_Identity=27.1493212669683, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI4503817, Length=198, Percent_Identity=24.7474747474747, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787335, Length=263, Percent_Identity=28.5171102661597, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI87082100, Length=270, Percent_Identity=30.7407407407407, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787905, Length=263, Percent_Identity=30.4182509505703, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790717, Length=263, Percent_Identity=23.9543726235741, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI87082160, Length=266, Percent_Identity=25.9398496240602, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786812, Length=266, Percent_Identity=26.3157894736842, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=24.6153846153846, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788459, Length=265, Percent_Identity=25.2830188679245, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787526, Length=220, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=26.6304347826087, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789208, Length=263, Percent_Identity=22.0532319391635, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI2367365, Length=266, Percent_Identity=25.187969924812, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=26.3358778625954, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=31.6793893129771, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=31.9066147859922, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17568967, Length=219, Percent_Identity=27.8538812785388, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17562906, Length=275, Percent_Identity=28.7272727272727, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=29.1512915129151, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=25.0980392156863, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=272, Percent_Identity=27.5735294117647, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=273, Percent_Identity=27.8388278388278, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=28.0898876404494, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=26.8939393939394, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=26.0700389105058, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=273, Percent_Identity=24.9084249084249, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=27.1375464684015, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=26.1363636363636, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=22.65625, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=25.7462686567164, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=26.5682656826568, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25152911, Length=185, Percent_Identity=31.3513513513514, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17559552, Length=190, Percent_Identity=31.5789473684211, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=25.2788104089219, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=280, Percent_Identity=24.6428571428571, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=171, Percent_Identity=30.9941520467836, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=26.5151515151515, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17570069, Length=128, Percent_Identity=32.03125, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=205, Percent_Identity=29.2682926829268, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21355319, Length=265, Percent_Identity=29.4339622641509, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=25.3846153846154, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=25.1937984496124, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24639444, Length=264, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24584744, Length=191, Percent_Identity=29.8429319371728, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574402, Length=191, Percent_Identity=29.8429319371728, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI161076933, Length=185, Percent_Identity=28.1081081081081, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584748, Length=185, Percent_Identity=28.1081081081081, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=29.5336787564767, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI18859837, Length=200, Percent_Identity=25.5, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=22.7450980392157, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=25.390625, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=24.031007751938, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 29133; Mature: 29133

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLHLTHKLALITGSTKGIGKAIATELAREGADVIINGRNQDEVDQVVADIKTQFPNTNP
CCCEEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCC
QGAAADIANEASRTHLFEQYPKVDILINNMGIFQPMEYADIDDATWNKFFQINVLAGNAL
CCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECCHH
AKFYLPKMLDQDFGRIIFIASEEAVMPSGEMPQYSMTKTMNLSLAKSLSKLTVATHVTVN
HHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEE
TIMPGSTLTEGVQQMLEDMYADSDLPKSEWEADFMKNHRSRSQIQRLIRPEEIGRFAAFV
EECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHEE
ASPDASSFSGEALRIDGGLVPTIF
ECCCCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MDLHLTHKLALITGSTKGIGKAIATELAREGADVIINGRNQDEVDQVVADIKTQFPNTNP
CCCEEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCC
QGAAADIANEASRTHLFEQYPKVDILINNMGIFQPMEYADIDDATWNKFFQINVLAGNAL
CCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECCHH
AKFYLPKMLDQDFGRIIFIASEEAVMPSGEMPQYSMTKTMNLSLAKSLSKLTVATHVTVN
HHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEE
TIMPGSTLTEGVQQMLEDMYADSDLPKSEWEADFMKNHRSRSQIQRLIRPEEIGRFAAFV
EECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHEE
ASPDASSFSGEALRIDGGLVPTIF
ECCCCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]