| Definition | Pediococcus pentosaceus ATCC 25745, complete genome. |
|---|---|
| Accession | NC_008525 |
| Length | 1,832,387 |
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The map label for this gene is ytbE [H]
Identifier: 116491843
GI number: 116491843
Start: 25243
End: 26082
Strand: Direct
Name: ytbE [H]
Synonym: PEPE_0025
Alternate gene names: 116491843
Gene position: 25243-26082 (Clockwise)
Preceding gene: 116491838
Following gene: 116491844
Centisome position: 1.38
GC content: 39.52
Gene sequence:
>840_bases ATGATTAATTCTTTAAACGATCGCATAATGTTAAATAATGGAACTGCAATCCCAGGGCTAGGTCTGGGAGTTTTTCAAAT TCCAGATGCAGATACGGCTCAAGTAGTTGCAAATGGAATCAAAAATGGTTACCGTTTAATCGACACAGCACAGATTTACG GAAATGAAGCGGGAACTGGAGCAGGCATTAAAGCCGGGTTGACGGCAACTGGTTTGAAGCGAGCCGATTTATTTGTCACT TCTAAGGTTTGGAATGACCACTTATCGTACGATGAAACGATAGCAGCCTTTGAGAGTAGTCTAAAGAAGTTAGGTTTAGA TTATTTGGATCTTTATCTAATTCATTGGCCAGGAGATAATGCATTTCAAGATGCATGGCGAGCACTAGAAACTTTATATA AACAAGGAAAGATTAAAGCGATTGGTGTAAGTAATTTCCAAATTCACCATCTCCAAGCTCTAGCGGAATTTGCTGAAATT ACACCGGTGATTAATCAAATCGAAACTCATCCGCAATTAAGTCAGCTCGAGATGCGAGAATATGCAGCTAAACATGATAT CAAAGTCCAAGCTTGGTCACCTTTGATGCAAGGAAAAATCTTAGACAACGCTGTGTTAGCTAAGATTGCCCAAAAGTACA ATAAGTCTGTCGCTCAGATTGTCCTACGGTGGGATGTTCAACAAAATATTTTGTTAGTAGTTAAATCAGTCCGTGCCGAA CGAATGCTAAGTAACGCGCAGATTTTTGATTTCGAATTAGCACCGGAAGATATGGACCAAATTAATGCTTTGAATGAAAA CTTGCGCGTCGGACCTAACCCAGATGAATTTGATTTTTAG
Upstream 100 bases:
>100_bases CATACTTTTTGGTATGTATAGCACAATAAAGTGGGTACTAGCTGAATAGAAACAGTTTAGTTATAGTTAAAATTATAATT GAACTTCAAAGGAGAAAAAA
Downstream 100 bases:
>100_bases ATTTTAGAAGGAGGTAAACTATGGATTTACATTTAACACATAAATTAGCTTTGATTACCGGCTCAACTAAAGGGATTGGG AAAGCCATTGCTACAGAATT
Product: aldo/keto reductase
Products: 2-keto-L-gulonate; NADP [C]
Alternate protein names: NA
Number of amino acids: Translated: 279; Mature: 279
Protein sequence:
>279_residues MINSLNDRIMLNNGTAIPGLGLGVFQIPDADTAQVVANGIKNGYRLIDTAQIYGNEAGTGAGIKAGLTATGLKRADLFVT SKVWNDHLSYDETIAAFESSLKKLGLDYLDLYLIHWPGDNAFQDAWRALETLYKQGKIKAIGVSNFQIHHLQALAEFAEI TPVINQIETHPQLSQLEMREYAAKHDIKVQAWSPLMQGKILDNAVLAKIAQKYNKSVAQIVLRWDVQQNILLVVKSVRAE RMLSNAQIFDFELAPEDMDQINALNENLRVGPNPDEFDF
Sequences:
>Translated_279_residues MINSLNDRIMLNNGTAIPGLGLGVFQIPDADTAQVVANGIKNGYRLIDTAQIYGNEAGTGAGIKAGLTATGLKRADLFVT SKVWNDHLSYDETIAAFESSLKKLGLDYLDLYLIHWPGDNAFQDAWRALETLYKQGKIKAIGVSNFQIHHLQALAEFAEI TPVINQIETHPQLSQLEMREYAAKHDIKVQAWSPLMQGKILDNAVLAKIAQKYNKSVAQIVLRWDVQQNILLVVKSVRAE RMLSNAQIFDFELAPEDMDQINALNENLRVGPNPDEFDF >Mature_279_residues MINSLNDRIMLNNGTAIPGLGLGVFQIPDADTAQVVANGIKNGYRLIDTAQIYGNEAGTGAGIKAGLTATGLKRADLFVT SKVWNDHLSYDETIAAFESSLKKLGLDYLDLYLIHWPGDNAFQDAWRALETLYKQGKIKAIGVSNFQIHHLQALAEFAEI TPVINQIETHPQLSQLEMREYAAKHDIKVQAWSPLMQGKILDNAVLAKIAQKYNKSVAQIVLRWDVQQNILLVVKSVRAE RMLSNAQIFDFELAPEDMDQINALNENLRVGPNPDEFDF
Specific function: Reduction [C]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=292, Percent_Identity=35.2739726027397, Blast_Score=196, Evalue=2e-50, Organism=Homo sapiens, GI5174391, Length=292, Percent_Identity=35.2739726027397, Blast_Score=196, Evalue=2e-50, Organism=Homo sapiens, GI223468663, Length=293, Percent_Identity=34.8122866894198, Blast_Score=186, Evalue=2e-47, Organism=Homo sapiens, GI93277124, Length=303, Percent_Identity=33.993399339934, Blast_Score=179, Evalue=2e-45, Organism=Homo sapiens, GI5174695, Length=305, Percent_Identity=32.7868852459016, Blast_Score=176, Evalue=2e-44, Organism=Homo sapiens, GI310109922, Length=277, Percent_Identity=33.2129963898917, Blast_Score=169, Evalue=3e-42, Organism=Homo sapiens, GI24497585, Length=298, Percent_Identity=32.5503355704698, Blast_Score=169, Evalue=3e-42, Organism=Homo sapiens, GI4502049, Length=300, Percent_Identity=36, Blast_Score=167, Evalue=9e-42, Organism=Homo sapiens, GI5453543, Length=297, Percent_Identity=31.6498316498317, Blast_Score=166, Evalue=2e-41, Organism=Homo sapiens, GI310109920, Length=297, Percent_Identity=31.6498316498317, Blast_Score=166, Evalue=2e-41, Organism=Homo sapiens, GI45446745, Length=297, Percent_Identity=31.6498316498317, Blast_Score=166, Evalue=3e-41, Organism=Homo sapiens, GI4503285, Length=297, Percent_Identity=31.6498316498317, Blast_Score=166, Evalue=3e-41, Organism=Homo sapiens, GI24497583, Length=312, Percent_Identity=31.7307692307692, Blast_Score=165, Evalue=5e-41, Organism=Homo sapiens, GI291291012, Length=278, Percent_Identity=34.1726618705036, Blast_Score=164, Evalue=7e-41, Organism=Homo sapiens, GI300116273, Length=284, Percent_Identity=30.6338028169014, Blast_Score=151, Evalue=8e-37, Organism=Homo sapiens, GI300116271, Length=283, Percent_Identity=31.095406360424, Blast_Score=150, Evalue=2e-36, Organism=Homo sapiens, GI310109926, Length=112, Percent_Identity=38.3928571428571, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI207028673, Length=112, Percent_Identity=38.3928571428571, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI310109924, Length=154, Percent_Identity=31.1688311688312, Blast_Score=88, Evalue=7e-18, Organism=Escherichia coli, GI87082198, Length=273, Percent_Identity=41.7582417582418, Blast_Score=227, Evalue=7e-61, Organism=Escherichia coli, GI1786400, Length=259, Percent_Identity=36.6795366795367, Blast_Score=164, Evalue=6e-42, Organism=Escherichia coli, GI1788081, Length=273, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=8e-29, Organism=Escherichia coli, GI87081735, Length=196, Percent_Identity=23.9795918367347, Blast_Score=65, Evalue=7e-12, Organism=Escherichia coli, GI1788070, Length=219, Percent_Identity=26.4840182648402, Blast_Score=62, Evalue=6e-11, Organism=Caenorhabditis elegans, GI71998625, Length=268, Percent_Identity=38.4328358208955, Blast_Score=194, Evalue=3e-50, Organism=Caenorhabditis elegans, GI17564128, Length=300, Percent_Identity=36.6666666666667, Blast_Score=185, Evalue=3e-47, Organism=Caenorhabditis elegans, GI17561298, Length=269, Percent_Identity=34.2007434944238, Blast_Score=182, Evalue=2e-46, Organism=Caenorhabditis elegans, GI17537077, Length=301, Percent_Identity=34.21926910299, Blast_Score=178, Evalue=3e-45, Organism=Caenorhabditis elegans, GI17537075, Length=310, Percent_Identity=33.8709677419355, Blast_Score=176, Evalue=1e-44, Organism=Caenorhabditis elegans, GI17552492, Length=263, Percent_Identity=32.319391634981, Blast_Score=165, Evalue=2e-41, Organism=Caenorhabditis elegans, GI17550248, Length=303, Percent_Identity=34.6534653465347, Blast_Score=159, Evalue=1e-39, Organism=Caenorhabditis elegans, GI17538386, Length=274, Percent_Identity=34.3065693430657, Blast_Score=158, Evalue=3e-39, Organism=Caenorhabditis elegans, GI17566692, Length=285, Percent_Identity=34.3859649122807, Blast_Score=154, Evalue=4e-38, Organism=Caenorhabditis elegans, GI17537079, Length=300, Percent_Identity=29.6666666666667, Blast_Score=154, Evalue=5e-38, Organism=Caenorhabditis elegans, GI17561300, Length=272, Percent_Identity=31.25, Blast_Score=144, Evalue=5e-35, Organism=Caenorhabditis elegans, GI17562292, Length=274, Percent_Identity=30.6569343065693, Blast_Score=142, Evalue=3e-34, Organism=Saccharomyces cerevisiae, GI6324694, Length=306, Percent_Identity=36.2745098039216, Blast_Score=175, Evalue=7e-45, Organism=Saccharomyces cerevisiae, GI6321896, Length=313, Percent_Identity=34.5047923322684, Blast_Score=174, Evalue=1e-44, Organism=Saccharomyces cerevisiae, GI6322556, Length=255, Percent_Identity=36.078431372549, Blast_Score=172, Evalue=5e-44, Organism=Saccharomyces cerevisiae, GI6319625, Length=296, Percent_Identity=33.445945945946, Blast_Score=164, Evalue=2e-41, Organism=Saccharomyces cerevisiae, GI6320576, Length=281, Percent_Identity=34.8754448398576, Blast_Score=161, Evalue=1e-40, Organism=Saccharomyces cerevisiae, GI6320079, Length=291, Percent_Identity=32.9896907216495, Blast_Score=137, Evalue=2e-33, Organism=Drosophila melanogaster, GI24662789, Length=294, Percent_Identity=38.0952380952381, Blast_Score=193, Evalue=1e-49, Organism=Drosophila melanogaster, GI24657054, Length=290, Percent_Identity=37.5862068965517, Blast_Score=183, Evalue=8e-47, Organism=Drosophila melanogaster, GI24663317, Length=293, Percent_Identity=33.7883959044369, Blast_Score=171, Evalue=7e-43, Organism=Drosophila melanogaster, GI21356425, Length=291, Percent_Identity=35.7388316151203, Blast_Score=169, Evalue=2e-42, Organism=Drosophila melanogaster, GI20129731, Length=295, Percent_Identity=32.2033898305085, Blast_Score=167, Evalue=9e-42, Organism=Drosophila melanogaster, GI24662785, Length=295, Percent_Identity=37.9661016949153, Blast_Score=166, Evalue=1e-41, Organism=Drosophila melanogaster, GI24662781, Length=294, Percent_Identity=38.0952380952381, Blast_Score=166, Evalue=2e-41, Organism=Drosophila melanogaster, GI45553081, Length=290, Percent_Identity=32.0689655172414, Blast_Score=162, Evalue=2e-40, Organism=Drosophila melanogaster, GI24644950, Length=300, Percent_Identity=31.6666666666667, Blast_Score=157, Evalue=6e-39, Organism=Drosophila melanogaster, GI221378297, Length=320, Percent_Identity=29.6875, Blast_Score=150, Evalue=1e-36, Organism=Drosophila melanogaster, GI281366140, Length=256, Percent_Identity=32.421875, Blast_Score=141, Evalue=5e-34,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: NA
Molecular weight: Translated: 31062; Mature: 31062
Theoretical pI: Translated: 5.14; Mature: 5.14
Prosite motif: PS00062 ALDOKETO_REDUCTASE_2 ; PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MINSLNDRIMLNNGTAIPGLGLGVFQIPDADTAQVVANGIKNGYRLIDTAQIYGNEAGTG CCCCCCCEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHCCCEEEEEHHHHHCCCCCCC AGIKAGLTATGLKRADLFVTSKVWNDHLSYDETIAAFESSLKKLGLDYLDLYLIHWPGDN CCCCCCCHHCCCCHHHEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC AFQDAWRALETLYKQGKIKAIGVSNFQIHHLQALAEFAEITPVINQIETHPQLSQLEMRE HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH YAAKHDIKVQAWSPLMQGKILDNAVLAKIAQKYNKSVAQIVLRWDVQQNILLVVKSVRAE HHHHCCCEEEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH RMLSNAQIFDFELAPEDMDQINALNENLRVGPNPDEFDF HHHCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCC >Mature Secondary Structure MINSLNDRIMLNNGTAIPGLGLGVFQIPDADTAQVVANGIKNGYRLIDTAQIYGNEAGTG CCCCCCCEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHCCCEEEEEHHHHHCCCCCCC AGIKAGLTATGLKRADLFVTSKVWNDHLSYDETIAAFESSLKKLGLDYLDLYLIHWPGDN CCCCCCCHHCCCCHHHEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC AFQDAWRALETLYKQGKIKAIGVSNFQIHHLQALAEFAEITPVINQIETHPQLSQLEMRE HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH YAAKHDIKVQAWSPLMQGKILDNAVLAKIAQKYNKSVAQIVLRWDVQQNILLVVKSVRAE HHHHCCCEEEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH RMLSNAQIFDFELAPEDMDQINALNENLRVGPNPDEFDF HHHCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: 2,5-diketo-D-gluconate; NADPH [C]
Specific reaction: 2,5-diketo-D-gluconate + NADPH = 2-keto-L-gulonate + NADP [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9387221; 9384377 [H]