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The map label for this gene is cobL [H]

Identifier: 116332609

GI number: 116332609

Start: 211049

End: 212290

Strand: Direct

Name: cobL [H]

Synonym: LBJ_4182

Alternate gene names: 116332609

Gene position: 211049-212290 (Clockwise)

Preceding gene: 116332608

Following gene: 116332610

Centisome position: 70.41

GC content: 42.75

Gene sequence:

>1242_bases
ATGAAAGCGGTTACCGTGATTGGAATGGGCGACGAAGGTTGCCTTGGGCTATCAAGCATTGCCGCAAACGCCGTCTCCAA
TGCACAAGTCCTTGCGGGAGGGAAAAGACACCTGGATTTTTTTCCCCAATTTTCAGGGGAAAAGATCGCATTGAAAGGGA
ACATTACGGAAGCGATCGAAAGAATCGCAGATCTTGCCTGCGAACATTCGGTATGTGTACTCGCATCCGGGGACCCTCTT
TTTTTCGGAATCGGAAGTTTAATCAGTAAAAAAATTGGACCGGAACACGTCGATTTTATTCCGGCGCCGAGTACAATCCA
ACAAGCCTTTGCAAGAGTGGGAATTCACTGGGACGACGCCAAAATTTTATCCTTACACGGAAGACCCATCGAAGGTCTCG
TCACAAAACTACAATCCCTTCGTAAGATTGCGTTGTTCACTGATGAATTCAATTGCCCGAAAACGATCGCTTCCTATCTA
TTATCTTTCGAGGAATCGGAATGGACCGCTTTCGTATGCGAAGATCTCGGGAACAAAAAGGAAAAAGTCCGCAAATTCGA
TCTTAAATCGTTAAGCGAAGAGGAGGGGATTAACCCTTTAAACGTCCTGATTCTTATTCTAAACGATACGTCTTGGAGAT
CTCCTCCGATAGTACCTAATGTTCCGGAAGAACATTACACAAAACGGACCCCAAAAAACGGACTCATCACAAAAAAAGAA
ATTCGAATTCTTTCCATTGCATTTTTGGATATCCGCAATGATAGCGTTGTTTGGGATATAGGAACCGGTTCCGGTTCGAT
TGCAATTGAAGCTGCACAACTCGCAAAAGACGGCAAAGTATACGCGATCGAATCCGATCCGGAAGGAATCGAAATTTGTA
AACAAAATATATATTCCAGAAAAACGGACAACGTATATGTAATTCCCGGGAAGGCTCCCGAAATTTTAGAATCCCTTCCC
AACCCGGACTGCATTTTTGTGGGAGGTTCCAAAGGAAACCTTTATGATATTATTCGAATTTCCTTAAATAGAATCGCTTC
TTTGGGAAGTTTAGTTATAAATGCAGTCACTCTGGATAACGTCGCGGAGGCTTATCACAGCTTTAAAAAGCTAAACCTTG
TTCCAGAAGTTACGCTTCTAAACATTTCCAGAGGACAACCTCTTGCGAATTATCTTAAATACGAAGCTCTAAACCCAATT
CATATTTTTAAAATCACAAAACCGGACGGATTTTCCGCATGA

Upstream 100 bases:

>100_bases
CGGTGCCGTATATTCTCACGAAAGGACGAAAAGGAGGAAGTACGATCGCCGTTGCGATTCTTCACACTCTTCTTCTTTTA
TCTTCCAAAAGAGGGGAAAA

Downstream 100 bases:

>100_bases
GTTCCGGTAAATATGGAAAACTTTACGGAGTTGGAGTCGGTCCAGGGGCCACTGACTTGATCACTCTCAGAGCAGTGCAT
ATTTTAAATTCGGTCTCAGT

Product: precorrin-6Y C5,15-methyltransferase (decarboxylating)

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKAVTVIGMGDEGCLGLSSIAANAVSNAQVLAGGKRHLDFFPQFSGEKIALKGNITEAIERIADLACEHSVCVLASGDPL
FFGIGSLISKKIGPEHVDFIPAPSTIQQAFARVGIHWDDAKILSLHGRPIEGLVTKLQSLRKIALFTDEFNCPKTIASYL
LSFEESEWTAFVCEDLGNKKEKVRKFDLKSLSEEEGINPLNVLILILNDTSWRSPPIVPNVPEEHYTKRTPKNGLITKKE
IRILSIAFLDIRNDSVVWDIGTGSGSIAIEAAQLAKDGKVYAIESDPEGIEICKQNIYSRKTDNVYVIPGKAPEILESLP
NPDCIFVGGSKGNLYDIIRISLNRIASLGSLVINAVTLDNVAEAYHSFKKLNLVPEVTLLNISRGQPLANYLKYEALNPI
HIFKITKPDGFSA

Sequences:

>Translated_413_residues
MKAVTVIGMGDEGCLGLSSIAANAVSNAQVLAGGKRHLDFFPQFSGEKIALKGNITEAIERIADLACEHSVCVLASGDPL
FFGIGSLISKKIGPEHVDFIPAPSTIQQAFARVGIHWDDAKILSLHGRPIEGLVTKLQSLRKIALFTDEFNCPKTIASYL
LSFEESEWTAFVCEDLGNKKEKVRKFDLKSLSEEEGINPLNVLILILNDTSWRSPPIVPNVPEEHYTKRTPKNGLITKKE
IRILSIAFLDIRNDSVVWDIGTGSGSIAIEAAQLAKDGKVYAIESDPEGIEICKQNIYSRKTDNVYVIPGKAPEILESLP
NPDCIFVGGSKGNLYDIIRISLNRIASLGSLVINAVTLDNVAEAYHSFKKLNLVPEVTLLNISRGQPLANYLKYEALNPI
HIFKITKPDGFSA
>Mature_413_residues
MKAVTVIGMGDEGCLGLSSIAANAVSNAQVLAGGKRHLDFFPQFSGEKIALKGNITEAIERIADLACEHSVCVLASGDPL
FFGIGSLISKKIGPEHVDFIPAPSTIQQAFARVGIHWDDAKILSLHGRPIEGLVTKLQSLRKIALFTDEFNCPKTIASYL
LSFEESEWTAFVCEDLGNKKEKVRKFDLKSLSEEEGINPLNVLILILNDTSWRSPPIVPNVPEEHYTKRTPKNGLITKKE
IRILSIAFLDIRNDSVVWDIGTGSGSIAIEAAQLAKDGKVYAIESDPEGIEICKQNIYSRKTDNVYVIPGKAPEILESLP
NPDCIFVGGSKGNLYDIIRISLNRIASLGSLVINAVTLDNVAEAYHSFKKLNLVPEVTLLNISRGQPLANYLKYEALNPI
HIFKITKPDGFSA

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 45151; Mature: 45151

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVTVIGMGDEGCLGLSSIAANAVSNAQVLAGGKRHLDFFPQFSGEKIALKGNITEAIE
CCEEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEECCHHHHHH
RIADLACEHSVCVLASGDPLFFGIGSLISKKIGPEHVDFIPAPSTIQQAFARVGIHWDDA
HHHHHHCCCCEEEEECCCCCEEEHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCCEECCC
KILSLHGRPIEGLVTKLQSLRKIALFTDEFNCPKTIASYLLSFEESEWTAFVCEDLGNKK
EEEEECCCCHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEHHHCCHH
EKVRKFDLKSLSEEEGINPLNVLILILNDTSWRSPPIVPNVPEEHYTKRTPKNGLITKKE
HHHHHHHHHHCHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHCCCCCCCCEEHHH
IRILSIAFLDIRNDSVVWDIGTGSGSIAIEAAQLAKDGKVYAIESDPEGIEICKQNIYSR
EEEEEEEEEEECCCEEEEEECCCCCCEEEEEEHHCCCCCEEEECCCCCHHHHHHHHHHCC
KTDNVYVIPGKAPEILESLPNPDCIFVGGSKGNLYDIIRISLNRIASLGSLVINAVTLDN
CCCCEEEECCCCHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
VAEAYHSFKKLNLVPEVTLLNISRGQPLANYLKYEALNPIHIFKITKPDGFSA
HHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MKAVTVIGMGDEGCLGLSSIAANAVSNAQVLAGGKRHLDFFPQFSGEKIALKGNITEAIE
CCEEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEECCHHHHHH
RIADLACEHSVCVLASGDPLFFGIGSLISKKIGPEHVDFIPAPSTIQQAFARVGIHWDDA
HHHHHHCCCCEEEEECCCCCEEEHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCCEECCC
KILSLHGRPIEGLVTKLQSLRKIALFTDEFNCPKTIASYLLSFEESEWTAFVCEDLGNKK
EEEEECCCCHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEHHHCCHH
EKVRKFDLKSLSEEEGINPLNVLILILNDTSWRSPPIVPNVPEEHYTKRTPKNGLITKKE
HHHHHHHHHHCHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHCCCCCCCCEEHHH
IRILSIAFLDIRNDSVVWDIGTGSGSIAIEAAQLAKDGKVYAIESDPEGIEICKQNIYSR
EEEEEEEEEEECCCEEEEEECCCCCCEEEEEEHHCCCCCEEEECCCCCHHHHHHHHHHCC
KTDNVYVIPGKAPEILESLPNPDCIFVGGSKGNLYDIIRISLNRIASLGSLVINAVTLDN
CCCCEEEECCCCHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
VAEAYHSFKKLNLVPEVTLLNISRGQPLANYLKYEALNPIHIFKITKPDGFSA
HHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]