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The map label for this gene is aroK

Identifier: 116332539

GI number: 116332539

Start: 122334

End: 122873

Strand: Reverse

Name: aroK

Synonym: LBJ_4105

Alternate gene names: 116332539

Gene position: 122873-122334 (Counterclockwise)

Preceding gene: 116332540

Following gene: 116332538

Centisome position: 40.99

GC content: 40.37

Gene sequence:

>540_bases
TTGAGAAAAAATTTTGCTCTGATCGGTCCGAGAGGGGTCGGAAAATCCAAAATTTCTCGCAAGCTTTCTAAAATAACAGG
AATGCCCGTAGTATCTACGGACATGATCGCAGTTTACGAGATGGGAGGGATTTCCATTCCGGAATTCATTCAAGAAAATG
AAGGGGATTGGAAAACTTTTCGAGACTTAGAGTTCCAAATCTTAGTAAAACTCAAAACCTCCCGTGGAATTATCTTAGAT
TGTGGAGGTGGCATTCTATTTGATTTGGATACCAAAGGGAAAGAGGTCCCTAGTAGCCGCAAAATTGATCTTTTAAAATC
CATTGCGGTCGTTTTTGGCCTTTCCAAGCCCACGGAAATTTTAGTGGAAAAGATTCAAAACGACCCTACTCGCCCTCCAC
TCAGTGCAATTAACTCCTATCGGAGCATAGTAGAGAATCGATTGCCCCATTATCGAAGTGTTTCGGATTATTATCTTGAA
ATAGATGATTTGAAGGTGGAAGAGGTTTGTTCTAGAATTCTGCACAAAATCGAATATTGA

Upstream 100 bases:

>100_bases
ATAAGGCCTTGCAAATGATAGGAACTACCGACTCTGATGTACAAATGTACTATACGACCCTTCCGGAAATACAGAAACAC
ATCCGCGAGTTGATTCAGGC

Downstream 100 bases:

>100_bases
ATTGACACATTTTGGCGATATTTGGTTCCCTTTTTCCAAAGCTTTTAGAAAAAGAATATCAAAATCATATAAAAGCAACT
AACGAGTCTCATCACTAAAT

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MRKNFALIGPRGVGKSKISRKLSKITGMPVVSTDMIAVYEMGGISIPEFIQENEGDWKTFRDLEFQILVKLKTSRGIILD
CGGGILFDLDTKGKEVPSSRKIDLLKSIAVVFGLSKPTEILVEKIQNDPTRPPLSAINSYRSIVENRLPHYRSVSDYYLE
IDDLKVEEVCSRILHKIEY

Sequences:

>Translated_179_residues
MRKNFALIGPRGVGKSKISRKLSKITGMPVVSTDMIAVYEMGGISIPEFIQENEGDWKTFRDLEFQILVKLKTSRGIILD
CGGGILFDLDTKGKEVPSSRKIDLLKSIAVVFGLSKPTEILVEKIQNDPTRPPLSAINSYRSIVENRLPHYRSVSDYYLE
IDDLKVEEVCSRILHKIEY
>Mature_179_residues
MRKNFALIGPRGVGKSKISRKLSKITGMPVVSTDMIAVYEMGGISIPEFIQENEGDWKTFRDLEFQILVKLKTSRGIILD
CGGGILFDLDTKGKEVPSSRKIDLLKSIAVVFGLSKPTEILVEKIQNDPTRPPLSAINSYRSIVENRLPHYRSVSDYYLE
IDDLKVEEVCSRILHKIEY

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=181, Percent_Identity=27.6243093922652, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_LEPBJ (Q04NM2)

Other databases:

- EMBL:   CP000351
- RefSeq:   YP_802256.1
- ProteinModelPortal:   Q04NM2
- SMR:   Q04NM2
- STRING:   Q04NM2
- GeneID:   4412400
- GenomeReviews:   CP000351_GR
- KEGG:   lbj:LBJ_4105
- eggNOG:   COG0703
- HOGENOM:   HBG335815
- OMA:   DPANCET
- ProtClustDB:   CLSK575331
- BioCyc:   LBOR355277:LBJ_4105-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 20217; Mature: 20217

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 34-34 BINDING 61-61 BINDING 83-83 BINDING 131-131 BINDING 147-147

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNFALIGPRGVGKSKISRKLSKITGMPVVSTDMIAVYEMGGISIPEFIQENEGDWKTF
CCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHCCCCCCHHH
RDLEFQILVKLKTSRGIILDCGGGILFDLDTKGKEVPSSRKIDLLKSIAVVFGLSKPTEI
HCCEEEEEEEEECCCCEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCHHH
LVEKIQNDPTRPPLSAINSYRSIVENRLPHYRSVSDYYLEIDDLKVEEVCSRILHKIEY
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKNFALIGPRGVGKSKISRKLSKITGMPVVSTDMIAVYEMGGISIPEFIQENEGDWKTF
CCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHCCCCCCHHH
RDLEFQILVKLKTSRGIILDCGGGILFDLDTKGKEVPSSRKIDLLKSIAVVFGLSKPTEI
HCCEEEEEEEEECCCCEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCHHH
LVEKIQNDPTRPPLSAINSYRSIVENRLPHYRSVSDYYLEIDDLKVEEVCSRILHKIEY
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA