Click here to switch to the map view.

The map label for this gene is argB [H]

Identifier: 116332532

GI number: 116332532

Start: 111053

End: 111928

Strand: Reverse

Name: argB [H]

Synonym: LBJ_4096

Alternate gene names: 116332532

Gene position: 111928-111053 (Counterclockwise)

Preceding gene: 116332534

Following gene: 116332531

Centisome position: 37.34

GC content: 44.29

Gene sequence:

>876_bases
ATGGAAAAACTTTTGGAAAGAGTCAATCACATCCTAGAAGCCCTTCCTTACATCACCAAATATTCAGGCAAGACGGTCGT
GATCAAATACGGCGGAGCCGCGATGGCTAAGGCCGATTTAAAAGAATCTTTTGCTAAAGATATCGTTCTTTTAAAGTATG
TAGGCATCCATCCCGTAATCGTTCACGGAGGAGGACCTGAAATCAATCGCCTCTTGGATAGCTTGAAAATTCCGACCGAA
TTCATTCACGGACATAGAGTCACCGACACTCAGACAATGGAAGTTGTGGAAATGGTTCTTACCGGTAAGGTAAATAAACA
AATCGTTTCTATGATCAATTCTCAAGGTGGAAAGGCTGTCGGAATTTCCGGCAAGGACGGTAACCTCGCAAAAGCGGTCA
AAGCTCCGATAGAGATCGAATTGGAAGGAAAGGCAAAACAGCTCTTCGATGTGGGGCTTGTAGGAAGAATCGAATCCATA
AATCCAGAAATTCTTCATAACCTCCAAAAGGAAGGGTTCATTCCTGTCATCTCCCCGGTAGCGGAAAGTGTGGAAGGAGA
CAGCCTAAACATCAACGCGGATACTTTCGCCGGTGAAATCGCAGGCGCTCTCAAAGCGGAAAAACTGATTCTTCTTACCG
ACACGGAAGGGATTTTGATCGACGGTAAATTAGCGACCGGACTCAGCCGAGGTAAAATGAAGGAATACATTCGAAAGGGA
GAAATTTCAGGCGGAATGATTCCTAAGGTGGAATGTTGTCTGGCAGCAATCGACCAAGGAGTGAATAGAACTCATATCAT
TGACGGAAGAGTTTCTCATTCCATCTTGATTGAAATTTTCACAAATCAGGGCATCGGTTCTTTGATCGAATCATGA

Upstream 100 bases:

>100_bases
TTCCTGATTTTTCGGAGACAATCTATAACCTCATAGTAGGCAATCTATTACTCTCTATTTCTAGATGACAGAGGAAGACA
CAAGGATTCTTTTGTTTCTC

Downstream 100 bases:

>100_bases
TCGACACGATTCCTTTTTCGAAGAGGGTACCATCATGCGTTCGATTAACGTCAATTTGTCTCGTTTTCCCGAAGTTTTCG
ATTCGTTGAAACTCCTTGAC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MEKLLERVNHILEALPYITKYSGKTVVIKYGGAAMAKADLKESFAKDIVLLKYVGIHPVIVHGGGPEINRLLDSLKIPTE
FIHGHRVTDTQTMEVVEMVLTGKVNKQIVSMINSQGGKAVGISGKDGNLAKAVKAPIEIELEGKAKQLFDVGLVGRIESI
NPEILHNLQKEGFIPVISPVAESVEGDSLNINADTFAGEIAGALKAEKLILLTDTEGILIDGKLATGLSRGKMKEYIRKG
EISGGMIPKVECCLAAIDQGVNRTHIIDGRVSHSILIEIFTNQGIGSLIES

Sequences:

>Translated_291_residues
MEKLLERVNHILEALPYITKYSGKTVVIKYGGAAMAKADLKESFAKDIVLLKYVGIHPVIVHGGGPEINRLLDSLKIPTE
FIHGHRVTDTQTMEVVEMVLTGKVNKQIVSMINSQGGKAVGISGKDGNLAKAVKAPIEIELEGKAKQLFDVGLVGRIESI
NPEILHNLQKEGFIPVISPVAESVEGDSLNINADTFAGEIAGALKAEKLILLTDTEGILIDGKLATGLSRGKMKEYIRKG
EISGGMIPKVECCLAAIDQGVNRTHIIDGRVSHSILIEIFTNQGIGSLIES
>Mature_291_residues
MEKLLERVNHILEALPYITKYSGKTVVIKYGGAAMAKADLKESFAKDIVLLKYVGIHPVIVHGGGPEINRLLDSLKIPTE
FIHGHRVTDTQTMEVVEMVLTGKVNKQIVSMINSQGGKAVGISGKDGNLAKAVKAPIEIELEGKAKQLFDVGLVGRIESI
NPEILHNLQKEGFIPVISPVAESVEGDSLNINADTFAGEIAGALKAEKLILLTDTEGILIDGKLATGLSRGKMKEYIRKG
EISGGMIPKVECCLAAIDQGVNRTHIIDGRVSHSILIEIFTNQGIGSLIES

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=296, Percent_Identity=28.3783783783784, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI145693208, Length=234, Percent_Identity=31.1965811965812, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320913, Length=283, Percent_Identity=27.5618374558304, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 31263; Mature: 31263

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLLERVNHILEALPYITKYSGKTVVIKYGGAAMAKADLKESFAKDIVLLKYVGIHPVI
CHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCEEE
VHGGGPEINRLLDSLKIPTEFIHGHRVTDTQTMEVVEMVLTGKVNKQIVSMINSQGGKAV
EECCCHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEE
GISGKDGNLAKAVKAPIEIELEGKAKQLFDVGLVGRIESINPEILHNLQKEGFIPVISPV
EECCCCCCHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEHHH
AESVEGDSLNINADTFAGEIAGALKAEKLILLTDTEGILIDGKLATGLSRGKMKEYIRKG
HHCCCCCEEEECHHHHHHHHHHHHHHCEEEEEECCCCEEEECHHHHCCCHHHHHHHHHHC
EISGGMIPKVECCLAAIDQGVNRTHIIDGRVSHSILIEIFTNQGIGSLIES
CCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCHHHHHCC
>Mature Secondary Structure
MEKLLERVNHILEALPYITKYSGKTVVIKYGGAAMAKADLKESFAKDIVLLKYVGIHPVI
CHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCEEE
VHGGGPEINRLLDSLKIPTEFIHGHRVTDTQTMEVVEMVLTGKVNKQIVSMINSQGGKAV
EECCCHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEE
GISGKDGNLAKAVKAPIEIELEGKAKQLFDVGLVGRIESINPEILHNLQKEGFIPVISPV
EECCCCCCHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEHHH
AESVEGDSLNINADTFAGEIAGALKAEKLILLTDTEGILIDGKLATGLSRGKMKEYIRKG
HHCCCCCEEEECHHHHHHHHHHHHHHCEEEEEECCCCEEEECHHHHCCCHHHHHHHHHHC
EISGGMIPKVECCLAAIDQGVNRTHIIDGRVSHSILIEIFTNQGIGSLIES
CCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA