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The map label for this gene is nuoC [H]

Identifier: 116329152

GI number: 116329152

Start: 3055111

End: 3055644

Strand: Reverse

Name: nuoC [H]

Synonym: LBL_2576

Alternate gene names: 116329152

Gene position: 3055644-3055111 (Counterclockwise)

Preceding gene: 116329153

Following gene: 116329151

Centisome position: 84.54

GC content: 42.88

Gene sequence:

>534_bases
ATGAAAGAAGAAGTAGAACGTTTTCTTAAAGAAAAATTTCCGCATTTTTTGGACGTACAAGAACCGGTCATTTCCAACGT
TCCGGTTTTTTATCTAAAGGCCGAAGGTATCGTTCCCGTATTGAACGCTCTTAAGGGCCATCCGACGCTGAATTATAATT
TTCTAAACGATTTAACCGCAGTGGATTGGCTCGGAAAAAAGGAGCCCCGATTCGAAGTCAATTATCTGCTTCGTTCCGCA
AATCAATCTTCAAGTAAAATCCGGATCAAAGTTCGCTTGGAAGACGGGGAAGCCATCCCAAGCGTGACTAACGTTTATAA
AGGAGCCAACTGGCCGGAAAGGGAAATTTATGATCTTTTCGGAATATCCTTTATCGGTCATCCGAACCTGGATCGGATTT
TGATGCCGGACAATTTTCAAGGACATCCCTTGCGGAAGGATTTTCCATTGGAAGGGTTCGGACAGGATTATCTGATCGAG
GATCTGCTTCATATCCACGTAAACGAAGATATAACCAAAAAAGGAGGGAAGTAG

Upstream 100 bases:

>100_bases
TGCAGACGAAACTGAAAACCCAGGGGTTGGAAGCGAGACGCCAGGAAGTGATGCAGAAAATCCAGGAATTGAATGAAAGA
AATAAACCCCTGGTCGTACG

Downstream 100 bases:

>100_bases
TATGATGTACGAAAAAACGGCGGAACATTTCGAGCAGAAATATAAAAATCTTCCCGAAGGACATCTTCTCGTAAATTTAG
GGCCTTCCCATCCGGCGACA

Product: NADH dehydrogenase (ubiquinone), C chain

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MKEEVERFLKEKFPHFLDVQEPVISNVPVFYLKAEGIVPVLNALKGHPTLNYNFLNDLTAVDWLGKKEPRFEVNYLLRSA
NQSSSKIRIKVRLEDGEAIPSVTNVYKGANWPEREIYDLFGISFIGHPNLDRILMPDNFQGHPLRKDFPLEGFGQDYLIE
DLLHIHVNEDITKKGGK

Sequences:

>Translated_177_residues
MKEEVERFLKEKFPHFLDVQEPVISNVPVFYLKAEGIVPVLNALKGHPTLNYNFLNDLTAVDWLGKKEPRFEVNYLLRSA
NQSSSKIRIKVRLEDGEAIPSVTNVYKGANWPEREIYDLFGISFIGHPNLDRILMPDNFQGHPLRKDFPLEGFGQDYLIE
DLLHIHVNEDITKKGGK
>Mature_177_residues
MKEEVERFLKEKFPHFLDVQEPVISNVPVFYLKAEGIVPVLNALKGHPTLNYNFLNDLTAVDWLGKKEPRFEVNYLLRSA
NQSSSKIRIKVRLEDGEAIPSVTNVYKGANWPEREIYDLFGISFIGHPNLDRILMPDNFQGHPLRKDFPLEGFGQDYLIE
DLLHIHVNEDITKKGGK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=146, Percent_Identity=39.7260273972603, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI145693162, Length=149, Percent_Identity=40.2684563758389, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=149, Percent_Identity=35.5704697986577, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI32563621, Length=149, Percent_Identity=35.5704697986577, Blast_Score=99, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24656494, Length=147, Percent_Identity=38.7755102040816, Blast_Score=103, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 20403; Mature: 20403

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEEVERFLKEKFPHFLDVQEPVISNVPVFYLKAEGIVPVLNALKGHPTLNYNFLNDLTA
CHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHH
VDWLGKKEPRFEVNYLLRSANQSSSKIRIKVRLEDGEAIPSVTNVYKGANWPEREIYDLF
HHHCCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHH
GISFIGHPNLDRILMPDNFQGHPLRKDFPLEGFGQDYLIEDLLHIHVNEDITKKGGK
CEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHCCCCC
>Mature Secondary Structure
MKEEVERFLKEKFPHFLDVQEPVISNVPVFYLKAEGIVPVLNALKGHPTLNYNFLNDLTA
CHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHH
VDWLGKKEPRFEVNYLLRSANQSSSKIRIKVRLEDGEAIPSVTNVYKGANWPEREIYDLF
HHHCCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHH
GISFIGHPNLDRILMPDNFQGHPLRKDFPLEGFGQDYLIEDLLHIHVNEDITKKGGK
CEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA