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The map label for this gene is pgk [H]

Identifier: 116327981

GI number: 116327981

Start: 1492087

End: 1493277

Strand: Reverse

Name: pgk [H]

Synonym: LBL_1270

Alternate gene names: 116327981

Gene position: 1493277-1492087 (Counterclockwise)

Preceding gene: 116327982

Following gene: 116327980

Centisome position: 41.31

GC content: 45.42

Gene sequence:

>1191_bases
ATGGAATTGCCTAGACTCGAAAACGTCGACCTCTCGGGAAAAAGAGTTTTTCTGAGGGTAGACTTCAACGTTCCCATAGA
AAACGGAAAAGTTACCGACAAAACCAGAATCGAAAAAACTCTTCCTACGATCGAACTTCTGATTAAAAAAGGAGCAAGAA
TAATCATTGCAAGCCATTTGGGAAGACCCAAAGGTCAAACAAATCCAGAATTCTCCTTAGCCCCGGTCGTAGAAGTCTTC
AAAGGACTCGTTAAGTCAAACGTCTATTTCTCTAAAACCGTAATCGGAGACGAACCGATCAAACTTTCCAAGGAACTGAG
AGACGGAGAAATCCTCGTGATCGAAAACGTCCGTTTTCATAAGGAAGAAGAAGAGAACGAACCGGGTTTTTCCAAAAAGC
TCGCCGCACTTGCGGACGTTTACGTCAACGACGCGTTCGGCGCTGCTCACAGGGCTCACGCATCTACGGAAGGAATCGCC
CATCTTCTTCCTGCATATGCGGGCCTTTTAATGCACAAAGAAATCGTGGAACTTTCCGCTCTTCTTGCAAAGCCCGCTCG
TCCGTTTGTTGCAATCATCGGCGGCTCCAAAGTTTCCTCAAAGATCAAGGTTTTAAACAACCTCTTTGACAAGGTAAATC
ATCTTCTCATCGGCGGCGGAATGGCATATACTTTCTTAAAATCCAGAGCGGTTCCGGTGGGAAATTCTCTGGTGGAAAAA
GACTTCGAAGTACAGGCCTTTCAACTGATCGAAAAAGCCGGAGTTGCAGGAGTGGATCTTCAACTTCCTGTGGATCATAT
CATCGGAGATCAATTCAACGAAAAAGCGAAGACCAAGTCCGTAGATAAAATGGGAATCTTAGACGGTTGGATGGGGATGG
ACATCGGTTCCAAAACGGTTTCGAACTACGAAAAGATCATCAAAAACGCAGGAACGATTTTTTGGAACGGACCGATGGGA
GTTTTTGAAATGGATAAATTCACGGGTGGAACGATGGCGATCGCGAAAGCGATTTCGAAATCCAAAGCGAAAACCGTAGT
CGGTGGTGGAGATTCCATCGCAGCAATCAACAAAGCGAAAGTTGCCGATAAGATTACCCATATTTCTACCGGCGGAGGCG
CTTCTCTCGAATTTATGGAAGGAAGAAAACTCCCCGGAGTGGAAGCTCTTAAGAAAAAAGTCTCCGAATAA

Upstream 100 bases:

>100_bases
CTCCAGATTCTTTAAGCTCGTTTCCTGGTATGACAACGAGATGGGATACTCCAACAGAGTTCTAGACCTCATCCGCTATA
TGGCGAAGAAAGGCTAGTTC

Downstream 100 bases:

>100_bases
AAGGTCCGGCTCTTTCACGATTTTTTCTTCTTATCGTAAAGAGCCGACTTATGATCCGGACTAAATGATATTTTCTTCAA
ATAGAGTTGGACAATCTTTT

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MELPRLENVDLSGKRVFLRVDFNVPIENGKVTDKTRIEKTLPTIELLIKKGARIIIASHLGRPKGQTNPEFSLAPVVEVF
KGLVKSNVYFSKTVIGDEPIKLSKELRDGEILVIENVRFHKEEEENEPGFSKKLAALADVYVNDAFGAAHRAHASTEGIA
HLLPAYAGLLMHKEIVELSALLAKPARPFVAIIGGSKVSSKIKVLNNLFDKVNHLLIGGGMAYTFLKSRAVPVGNSLVEK
DFEVQAFQLIEKAGVAGVDLQLPVDHIIGDQFNEKAKTKSVDKMGILDGWMGMDIGSKTVSNYEKIIKNAGTIFWNGPMG
VFEMDKFTGGTMAIAKAISKSKAKTVVGGGDSIAAINKAKVADKITHISTGGGASLEFMEGRKLPGVEALKKKVSE

Sequences:

>Translated_396_residues
MELPRLENVDLSGKRVFLRVDFNVPIENGKVTDKTRIEKTLPTIELLIKKGARIIIASHLGRPKGQTNPEFSLAPVVEVF
KGLVKSNVYFSKTVIGDEPIKLSKELRDGEILVIENVRFHKEEEENEPGFSKKLAALADVYVNDAFGAAHRAHASTEGIA
HLLPAYAGLLMHKEIVELSALLAKPARPFVAIIGGSKVSSKIKVLNNLFDKVNHLLIGGGMAYTFLKSRAVPVGNSLVEK
DFEVQAFQLIEKAGVAGVDLQLPVDHIIGDQFNEKAKTKSVDKMGILDGWMGMDIGSKTVSNYEKIIKNAGTIFWNGPMG
VFEMDKFTGGTMAIAKAISKSKAKTVVGGGDSIAAINKAKVADKITHISTGGGASLEFMEGRKLPGVEALKKKVSE
>Mature_396_residues
MELPRLENVDLSGKRVFLRVDFNVPIENGKVTDKTRIEKTLPTIELLIKKGARIIIASHLGRPKGQTNPEFSLAPVVEVF
KGLVKSNVYFSKTVIGDEPIKLSKELRDGEILVIENVRFHKEEEENEPGFSKKLAALADVYVNDAFGAAHRAHASTEGIA
HLLPAYAGLLMHKEIVELSALLAKPARPFVAIIGGSKVSSKIKVLNNLFDKVNHLLIGGGMAYTFLKSRAVPVGNSLVEK
DFEVQAFQLIEKAGVAGVDLQLPVDHIIGDQFNEKAKTKSVDKMGILDGWMGMDIGSKTVSNYEKIIKNAGTIFWNGPMG
VFEMDKFTGGTMAIAKAISKSKAKTVVGGGDSIAAINKAKVADKITHISTGGGASLEFMEGRKLPGVEALKKKVSE

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI31543397, Length=407, Percent_Identity=43.4889434889435, Blast_Score=328, Evalue=5e-90,
Organism=Homo sapiens, GI4505763, Length=408, Percent_Identity=43.1372549019608, Blast_Score=325, Evalue=4e-89,
Organism=Escherichia coli, GI1789294, Length=403, Percent_Identity=44.4168734491315, Blast_Score=320, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI17508823, Length=406, Percent_Identity=43.8423645320197, Blast_Score=342, Evalue=2e-94,
Organism=Saccharomyces cerevisiae, GI6319857, Length=408, Percent_Identity=43.6274509803922, Blast_Score=323, Evalue=2e-89,
Organism=Drosophila melanogaster, GI17136394, Length=406, Percent_Identity=44.5812807881773, Blast_Score=317, Evalue=7e-87,
Organism=Drosophila melanogaster, GI24581203, Length=407, Percent_Identity=41.031941031941, Blast_Score=297, Evalue=1e-80,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 42855; Mature: 42855

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELPRLENVDLSGKRVFLRVDFNVPIENGKVTDKTRIEKTLPTIELLIKKGARIIIASHL
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
GRPKGQTNPEFSLAPVVEVFKGLVKSNVYFSKTVIGDEPIKLSKELRDGEILVIENVRFH
CCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCCEEEEECCEEC
KEEEENEPGFSKKLAALADVYVNDAFGAAHRAHASTEGIAHLLPAYAGLLMHKEIVELSA
CCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLAKPARPFVAIIGGSKVSSKIKVLNNLFDKVNHLLIGGGMAYTFLKSRAVPVGNSLVEK
HHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCCCCHHHHC
DFEVQAFQLIEKAGVAGVDLQLPVDHIIGDQFNEKAKTKSVDKMGILDGWMGMDIGSKTV
CCHHHHHHHHHHCCCCCEEEECCHHHHHCCCHHHHHHHCCCHHHHCCCCCCCCCCCHHHH
SNYEKIIKNAGTIFWNGPMGVFEMDKFTGGTMAIAKAISKSKAKTVVGGGDSIAAINKAK
HHHHHHHHCCCEEEECCCCCCEEECCCCCHHHHHHHHHHHHHCCEEECCCCCEEHHHHHH
VADKITHISTGGGASLEFMEGRKLPGVEALKKKVSE
HHHHHHEEECCCCCEEEEECCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MELPRLENVDLSGKRVFLRVDFNVPIENGKVTDKTRIEKTLPTIELLIKKGARIIIASHL
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
GRPKGQTNPEFSLAPVVEVFKGLVKSNVYFSKTVIGDEPIKLSKELRDGEILVIENVRFH
CCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCCEEEEECCEEC
KEEEENEPGFSKKLAALADVYVNDAFGAAHRAHASTEGIAHLLPAYAGLLMHKEIVELSA
CCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLAKPARPFVAIIGGSKVSSKIKVLNNLFDKVNHLLIGGGMAYTFLKSRAVPVGNSLVEK
HHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCCCCHHHHC
DFEVQAFQLIEKAGVAGVDLQLPVDHIIGDQFNEKAKTKSVDKMGILDGWMGMDIGSKTV
CCHHHHHHHHHHCCCCCEEEECCHHHHHCCCHHHHHHHCCCHHHHCCCCCCCCCCCHHHH
SNYEKIIKNAGTIFWNGPMGVFEMDKFTGGTMAIAKAISKSKAKTVVGGGDSIAAINKAK
HHHHHHHHCCCEEEECCCCCCEEECCCCCHHHHHHHHHHHHHCCEEECCCCCEEHHHHHH
VADKITHISTGGGASLEFMEGRKLPGVEALKKKVSE
HHHHHHEEECCCCCEEEEECCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA