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The map label for this gene is lspA

Identifier: 116327613

GI number: 116327613

Start: 981703

End: 982251

Strand: Direct

Name: lspA

Synonym: LBL_0845

Alternate gene names: 116327613

Gene position: 981703-982251 (Clockwise)

Preceding gene: 116327612

Following gene: 116327614

Centisome position: 27.16

GC content: 42.99

Gene sequence:

>549_bases
GTGAAATATTTTGAAAAACGATTTTTAGACGTCTATCGCCCTCTTTATATAGGCGTTATCTTTCTCGGGATCATATTGGA
TCTTGTGACTAAGTTTCTCGTCATTCTCTACTTTGAACCGCACCGTTATTTGGAGGTGCTTGGAAGTTTTTTCAGAATGA
CTCTTACCTTCAATACCGGCTTCGTGTTCGGAGCGTTTCAAGATAATGCGATTCCGTCTTTGATCGCAACCGGAATCGCA
ATTGTGTTTCTCATCGGATACAGATGGAAAAATTACGATCTTGGAAATCCTTGGGGGTGGAATCTCGTTATGGCCGGTGC
TTTTGGAAATTTTTTGGATAAGTTCTTCGTAAAAATTCCGGGCACGGGATTCCGTTTCGGGTTTCAACCGAACGTGGGAG
AATACATCGGAGTCGTCGATTTCTTGGATTTCGATTGGCCGGACTTTCTTCTTTTTTCAAGATGGCCTGCGTTCAATGTG
GCGGATTCCTGCGTGACGATCGGACTTACGATTCTGATCTTTACGATGAAACTCGAAGAGGAGAAATAA

Upstream 100 bases:

>100_bases
AAATTCAAGGTTGGGGATTTTGGGGAATCTCCGGATTTTTTGGACTGTTAGTTATTTATTCATTTTGGAAACACAAACTT
AAAAAGAAAGGAACTCTCTC

Downstream 100 bases:

>100_bases
TTTCTTGAAAGCTCTCGATCTACCCATCTGGAGAAAATTATTCATTCGTAAGGAAGCGAATAACAAGGCGATCATTCAGT
TTCTCAGGGAAACTTCCGTT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKYFEKRFLDVYRPLYIGVIFLGIILDLVTKFLVILYFEPHRYLEVLGSFFRMTLTFNTGFVFGAFQDNAIPSLIATGIA
IVFLIGYRWKNYDLGNPWGWNLVMAGAFGNFLDKFFVKIPGTGFRFGFQPNVGEYIGVVDFLDFDWPDFLLFSRWPAFNV
ADSCVTIGLTILIFTMKLEEEK

Sequences:

>Translated_182_residues
MKYFEKRFLDVYRPLYIGVIFLGIILDLVTKFLVILYFEPHRYLEVLGSFFRMTLTFNTGFVFGAFQDNAIPSLIATGIA
IVFLIGYRWKNYDLGNPWGWNLVMAGAFGNFLDKFFVKIPGTGFRFGFQPNVGEYIGVVDFLDFDWPDFLLFSRWPAFNV
ADSCVTIGLTILIFTMKLEEEK
>Mature_182_residues
MKYFEKRFLDVYRPLYIGVIFLGIILDLVTKFLVILYFEPHRYLEVLGSFFRMTLTFNTGFVFGAFQDNAIPSLIATGIA
IVFLIGYRWKNYDLGNPWGWNLVMAGAFGNFLDKFFVKIPGTGFRFGFQPNVGEYIGVVDFLDFDWPDFLLFSRWPAFNV
ADSCVTIGLTILIFTMKLEEEK

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LSPA_LEPBJ (Q04QT4)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_801494.1
- STRING:   Q04QT4
- GeneID:   4410985
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_2262
- HOGENOM:   HBG724422
- OMA:   NFFRIIH
- ProtClustDB:   PRK14783
- BioCyc:   LBOR355277:LBJ_2262-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_00161
- InterPro:   IPR001872
- PRINTS:   PR00781

Pfam domain/function: PF01252 Peptidase_A8

EC number: =3.4.23.36

Molecular weight: Translated: 21077; Mature: 21077

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00855 SPASE_II

Important sites: ACT_SITE 113-113 ACT_SITE 162-162

Signals:

None

Transmembrane regions:

HASH(0xea2d434)-; HASH(0xf4f8500)-; HASH(0xf86a904)-; HASH(0xf871fc4)-; HASH(0xdda4284)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYFEKRFLDVYRPLYIGVIFLGIILDLVTKFLVILYFEPHRYLEVLGSFFRMTLTFNTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEECCC
FVFGAFQDNAIPSLIATGIAIVFLIGYRWKNYDLGNPWGWNLVMAGAFGNFLDKFFVKIP
EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCC
GTGFRFGFQPNVGEYIGVVDFLDFDWPDFLLFSRWPAFNVADSCVTIGLTILIFTMKLEE
CCCEEECCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
EK
CH
>Mature Secondary Structure
MKYFEKRFLDVYRPLYIGVIFLGIILDLVTKFLVILYFEPHRYLEVLGSFFRMTLTFNTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEECCC
FVFGAFQDNAIPSLIATGIAIVFLIGYRWKNYDLGNPWGWNLVMAGAFGNFLDKFFVKIP
EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCC
GTGFRFGFQPNVGEYIGVVDFLDFDWPDFLLFSRWPAFNVADSCVTIGLTILIFTMKLEE
CCCEEECCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
EK
CH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA