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The map label for this gene is crp [C]

Identifier: 116327614

GI number: 116327614

Start: 982256

End: 982783

Strand: Direct

Name: crp [C]

Synonym: LBL_0846

Alternate gene names: 116327614

Gene position: 982256-982783 (Clockwise)

Preceding gene: 116327613

Following gene: 116327615

Centisome position: 27.18

GC content: 42.8

Gene sequence:

>528_bases
TTGAAAGCTCTCGATCTACCCATCTGGAGAAAATTATTCATTCGTAAGGAAGCGAATAACAAGGCGATCATTCAGTTTCT
CAGGGAAACTTCCGTTTTTGGGAGAATGAAAAAAAGAACCCTAATTGAAATCGCAAGGATGGTGCACGTTCGAGAGTATC
AGGAAAGTGAAATGGTCTTTCGTCAGGGAGACGTCGGGGCCGGATTTTATCTGGTCTATGAAGGTTCGGTCGTAATCCGC
TCCGTTAGAGATGGAATCGAACTTGATCTCGCTCATCTGGATCAGCATTCTTTCTTCGGAGAACTTTCCCTTTTTACGGA
AGAAAGAAGAACTGCTAGCGCGATCACTCTTGAACCGACCACTTTGCTCGGATTTTTCCAACCCGATCTCAAAGAAATCA
TAGAAACAAAGCCGAGGATTGGCATTGAAATTCTCATGAGTCTTTCTACGGTGATCGTAGAAAGACTACATAGAACCAAC
GGGCTTTTAGAAAAAGCCTACTTCAAAGGAAAACAAAAAAATGCGTGA

Upstream 100 bases:

>100_bases
TTTTCAAGATGGCCTGCGTTCAATGTGGCGGATTCCTGCGTGACGATCGGACTTACGATTCTGATCTTTACGATGAAACT
CGAAGAGGAGAAATAATTTC

Downstream 100 bases:

>100_bases
TCCGGAAATCAGGGAATTTTCCGGATACTTCATTCGGACGAGTTTTTTTCTTATTGTTGTTTTTACGACCGTCGTTTCTC
TTTGGGGACTTCAATTACTT

Product: cAMP-binding protein

Products: NA

Alternate protein names: Crp Family Transcriptional Regulator; Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; CAMP-Dependent Protein Kinase

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MKALDLPIWRKLFIRKEANNKAIIQFLRETSVFGRMKKRTLIEIARMVHVREYQESEMVFRQGDVGAGFYLVYEGSVVIR
SVRDGIELDLAHLDQHSFFGELSLFTEERRTASAITLEPTTLLGFFQPDLKEIIETKPRIGIEILMSLSTVIVERLHRTN
GLLEKAYFKGKQKNA

Sequences:

>Translated_175_residues
MKALDLPIWRKLFIRKEANNKAIIQFLRETSVFGRMKKRTLIEIARMVHVREYQESEMVFRQGDVGAGFYLVYEGSVVIR
SVRDGIELDLAHLDQHSFFGELSLFTEERRTASAITLEPTTLLGFFQPDLKEIIETKPRIGIEILMSLSTVIVERLHRTN
GLLEKAYFKGKQKNA
>Mature_175_residues
MKALDLPIWRKLFIRKEANNKAIIQFLRETSVFGRMKKRTLIEIARMVHVREYQESEMVFRQGDVGAGFYLVYEGSVVIR
SVRDGIELDLAHLDQHSFFGELSLFTEERRTASAITLEPTTLLGFFQPDLKEIIETKPRIGIEILMSLSTVIVERLHRTN
GLLEKAYFKGKQKNA

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 20245; Mature: 20245

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALDLPIWRKLFIRKEANNKAIIQFLRETSVFGRMKKRTLIEIARMVHVREYQESEMVF
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQGDVGAGFYLVYEGSVVIRSVRDGIELDLAHLDQHSFFGELSLFTEERRTASAITLEPT
HCCCCCCCEEEEEECHHHEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECHH
TLLGFFQPDLKEIIETKPRIGIEILMSLSTVIVERLHRTNGLLEKAYFKGKQKNA
HHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MKALDLPIWRKLFIRKEANNKAIIQFLRETSVFGRMKKRTLIEIARMVHVREYQESEMVF
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQGDVGAGFYLVYEGSVVIRSVRDGIELDLAHLDQHSFFGELSLFTEERRTASAITLEPT
HCCCCCCCEEEEEECHHHEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECHH
TLLGFFQPDLKEIIETKPRIGIEILMSLSTVIVERLHRTNGLLEKAYFKGKQKNA
HHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA