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The map label for this gene is coaD

Identifier: 116327009

GI number: 116327009

Start: 212469

End: 212951

Strand: Direct

Name: coaD

Synonym: LBL_0179

Alternate gene names: 116327009

Gene position: 212469-212951 (Clockwise)

Preceding gene: 116327008

Following gene: 116327010

Centisome position: 5.88

GC content: 40.17

Gene sequence:

>483_bases
ATGAAACATTTGGCGATTTATCCGGGTTCCTTTGATCCGTTAACAAACGGACATTTGGATATTCTTCAAAGGTCTTTGGG
ACTTTTCGACAAGGTGATCATTGCTATTGCGGTCAATTCCAACAAGTCCACTTTGTTCTCAATCGAGGAAAGGCTCGAAT
TTATCCACAAAGTCACCCAAGGATTAAAAGGTCTGGAGATCGATACTTTTCAAGGTCTCACCGTGGATTATTGCAATAAA
GTTGGAGCAAATAGTATTATTCGAGGGCTCAGAGCGGTTACCGATTTCGACTATGAATATGCCATTTCCTTAATGAATAA
AAAATTGGCTCCAAATGTGGAAACCGTTTTTCTCATGTCTTCCGGCGAATATTCTTTTATCTCCTCGACGATCGTAAAGG
AAGTCGCAAGACATGGAAGAGACGTTAGCAATCAGGTTCCCGAAATTGTCGGCAAAGCATTACTTAAAAAACTCTCTCAA
TAA

Upstream 100 bases:

>100_bases
CAACCTTTGAAAAAGAGGAATTATATAACCAAAAAGACGCGGAAGGGTTTATCAATATCTACGGTTTACCTGCGCAAGAA
ACGGCTAGGCTTCGTAAAAA

Downstream 100 bases:

>100_bases
GGAAAAAAAATGTCCAAAACGTTTATCATGATCAAACCCGACGGAGTAAAAAACAAACACGTCGGGAACATTCTTGCAAG
GATCGAAAAGGAAGGATTTA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKHLAIYPGSFDPLTNGHLDILQRSLGLFDKVIIAIAVNSNKSTLFSIEERLEFIHKVTQGLKGLEIDTFQGLTVDYCNK
VGANSIIRGLRAVTDFDYEYAISLMNKKLAPNVETVFLMSSGEYSFISSTIVKEVARHGRDVSNQVPEIVGKALLKKLSQ

Sequences:

>Translated_160_residues
MKHLAIYPGSFDPLTNGHLDILQRSLGLFDKVIIAIAVNSNKSTLFSIEERLEFIHKVTQGLKGLEIDTFQGLTVDYCNK
VGANSIIRGLRAVTDFDYEYAISLMNKKLAPNVETVFLMSSGEYSFISSTIVKEVARHGRDVSNQVPEIVGKALLKKLSQ
>Mature_160_residues
MKHLAIYPGSFDPLTNGHLDILQRSLGLFDKVIIAIAVNSNKSTLFSIEERLEFIHKVTQGLKGLEIDTFQGLTVDYCNK
VGANSIIRGLRAVTDFDYEYAISLMNKKLAPNVETVFLMSSGEYSFISSTIVKEVARHGRDVSNQVPEIVGKALLKKLSQ

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=48.4276729559748, Blast_Score=167, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_LEPBJ (Q04P85)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_802043.1
- ProteinModelPortal:   Q04P85
- SMR:   Q04P85
- STRING:   Q04P85
- GeneID:   4412154
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_2884
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q04P85
- ProtClustDB:   PRK00168
- BioCyc:   LBOR355277:LBJ_2884-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17762; Mature: 17762

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHLAIYPGSFDPLTNGHLDILQRSLGLFDKVIIAIAVNSNKSTLFSIEERLEFIHKVTQ
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHH
GLKGLEIDTFQGLTVDYCNKVGANSIIRGLRAVTDFDYEYAISLMNKKLAPNVETVFLMS
CCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEC
SGEYSFISSTIVKEVARHGRDVSNQVPEIVGKALLKKLSQ
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKHLAIYPGSFDPLTNGHLDILQRSLGLFDKVIIAIAVNSNKSTLFSIEERLEFIHKVTQ
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHH
GLKGLEIDTFQGLTVDYCNKVGANSIIRGLRAVTDFDYEYAISLMNKKLAPNVETVFLMS
CCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEC
SGEYSFISSTIVKEVARHGRDVSNQVPEIVGKALLKKLSQ
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA