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The map label for this gene is gsiC [H]

Identifier: 116249274

GI number: 116249274

Start: 661587

End: 662537

Strand: Reverse

Name: gsiC [H]

Synonym: pRL120609

Alternate gene names: 116249274

Gene position: 662537-661587 (Counterclockwise)

Preceding gene: 116249275

Following gene: 116249273

Centisome position: 76.15

GC content: 61.09

Gene sequence:

>951_bases
GTGAACCGCCAGGTCTTATCCCTTGTACTGAGCAGATTGTTCGTCGCCGTGATCACCCTGGTGATCGTCTCCTTCGCCGT
CTTCTTCGCGACAACGCTGTTGCCTGGAGATACGGCGACGATCCTGCTCGGCCAAGCCGCCACCCCGGAAGCCGTCGAAG
GCCTGCGCAAGGCCATGCATCTCGACGAACCGGCGCTCTTTCGGTTCCTGCGCTGGTTAGTCGGGCTGCTGCAAGGCGAC
CTCGGCACCTCCTATGCCAACGACATGCCGATCGCCGCTCTCATCGCCGGCCGCTTCGTCAACACGCTGAAACTTGCCGG
CGTCACCGCGCTTTTCTCCGTACCGATCGCGCTGACGCTCGGGATCACTGCGGCGATGCTGCGCGGCACCCTTTACGACC
GGATTGTCACGGTGATCACCATCGGCGTCATCTCCGTGCCGGAGTTCATGGTCGCGACCTCCGCGGCGCTCATCTTTGCC
GTCTATCTGAAATGGCTGCCGGCACTTTCTTTCGCCAATGAGGTCCACAGTTTGACCGATCTGTTGCGGGTCTATGCCAT
GCCCGTGATCACCCTCACCTTCGTCGTCTCGGCCCAGATGATCCGCATGACGCGGGCGGCTGTCATCGAGACGCTCAACA
CGCCCTATGTCGAGATGGCATTGCTGAAGGGCGCTTCCCGGCCGCGCATCGTCTTTCGCCATGCACTGCCGAATGCGCTC
GGCCCGATCGTCAATGCCGTTGCGCTTTCGCTGTCCTATCTGCTTGGAGGCGTGATCATCGTCGAGACCATTTTCAACTA
TCCCGGTATCGCCAAGCTGATGCTGGATGCCGTCGCCACCCGCGACCTGCCGCTGATCCAGAGCTGCGCGATGATCTTCT
GCCTGGGCTATCTGCTGCTGATCACCATCGCCGACATCATCGCCATCCTTTCCAATCCGAGGCTCCGATGA

Upstream 100 bases:

>100_bases
TTGAAGCCTGATGCAGCAAAGGAGACTGGGGCTGCAGCCGCGCCCCAGTTCGTCCATCTGCCTTGATGGAACTCAACTCG
AACGCAAAGGGAAGACGCCC

Downstream 100 bases:

>100_bases
CCATGACCAGTTCTGAAACCACCTCCGGCCGGCTGTCCGGAACCCGGTTTGGCTATCGCTTCAACATCGTCGGCGCGATC
GGCTTCACTGTGATCCTCTT

Product: putative permease component of ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNRQVLSLVLSRLFVAVITLVIVSFAVFFATTLLPGDTATILLGQAATPEAVEGLRKAMHLDEPALFRFLRWLVGLLQGD
LGTSYANDMPIAALIAGRFVNTLKLAGVTALFSVPIALTLGITAAMLRGTLYDRIVTVITIGVISVPEFMVATSAALIFA
VYLKWLPALSFANEVHSLTDLLRVYAMPVITLTFVVSAQMIRMTRAAVIETLNTPYVEMALLKGASRPRIVFRHALPNAL
GPIVNAVALSLSYLLGGVIIVETIFNYPGIAKLMLDAVATRDLPLIQSCAMIFCLGYLLLITIADIIAILSNPRLR

Sequences:

>Translated_316_residues
MNRQVLSLVLSRLFVAVITLVIVSFAVFFATTLLPGDTATILLGQAATPEAVEGLRKAMHLDEPALFRFLRWLVGLLQGD
LGTSYANDMPIAALIAGRFVNTLKLAGVTALFSVPIALTLGITAAMLRGTLYDRIVTVITIGVISVPEFMVATSAALIFA
VYLKWLPALSFANEVHSLTDLLRVYAMPVITLTFVVSAQMIRMTRAAVIETLNTPYVEMALLKGASRPRIVFRHALPNAL
GPIVNAVALSLSYLLGGVIIVETIFNYPGIAKLMLDAVATRDLPLIQSCAMIFCLGYLLLITIADIIAILSNPRLR
>Mature_316_residues
MNRQVLSLVLSRLFVAVITLVIVSFAVFFATTLLPGDTATILLGQAATPEAVEGLRKAMHLDEPALFRFLRWLVGLLQGD
LGTSYANDMPIAALIAGRFVNTLKLAGVTALFSVPIALTLGITAAMLRGTLYDRIVTVITIGVISVPEFMVATSAALIFA
VYLKWLPALSFANEVHSLTDLLRVYAMPVITLTFVVSAQMIRMTRAAVIETLNTPYVEMALLKGASRPRIVFRHALPNAL
GPIVNAVALSLSYLLGGVIIVETIFNYPGIAKLMLDAVATRDLPLIQSCAMIFCLGYLLLITIADIIAILSNPRLR

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=312, Percent_Identity=34.9358974358974, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=27.0833333333333, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1789888, Length=315, Percent_Identity=29.2063492063492, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1787497, Length=314, Percent_Identity=28.0254777070064, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787761, Length=307, Percent_Identity=29.3159609120521, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787550, Length=267, Percent_Identity=28.8389513108614, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1788504, Length=282, Percent_Identity=24.822695035461, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34126; Mature: 34126

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRQVLSLVLSRLFVAVITLVIVSFAVFFATTLLPGDTATILLGQAATPEAVEGLRKAMH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHC
LDEPALFRFLRWLVGLLQGDLGTSYANDMPIAALIAGRFVNTLKLAGVTALFSVPIALTL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITAAMLRGTLYDRIVTVITIGVISVPEFMVATSAALIFAVYLKWLPALSFANEVHSLTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRVYAMPVITLTFVVSAQMIRMTRAAVIETLNTPYVEMALLKGASRPRIVFRHALPNAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCHHH
GPIVNAVALSLSYLLGGVIIVETIFNYPGIAKLMLDAVATRDLPLIQSCAMIFCLGYLLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ITIADIIAILSNPRLR
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNRQVLSLVLSRLFVAVITLVIVSFAVFFATTLLPGDTATILLGQAATPEAVEGLRKAMH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHC
LDEPALFRFLRWLVGLLQGDLGTSYANDMPIAALIAGRFVNTLKLAGVTALFSVPIALTL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITAAMLRGTLYDRIVTVITIGVISVPEFMVATSAALIFAVYLKWLPALSFANEVHSLTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRVYAMPVITLTFVVSAQMIRMTRAAVIETLNTPYVEMALLKGASRPRIVFRHALPNAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCHHH
GPIVNAVALSLSYLLGGVIIVETIFNYPGIAKLMLDAVATRDLPLIQSCAMIFCLGYLLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ITIADIIAILSNPRLR
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA