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The map label for this gene is cscR [H]

Identifier: 116249219

GI number: 116249219

Start: 603666

End: 604676

Strand: Direct

Name: cscR [H]

Synonym: pRL120555

Alternate gene names: 116249219

Gene position: 603666-604676 (Clockwise)

Preceding gene: 116249218

Following gene: 116249220

Centisome position: 69.39

GC content: 66.37

Gene sequence:

>1011_bases
ATGGTGCGGATCGTGGCAGTATCTCTTTCTGACATCGCGGAACGTGCGGGCGTCTCGGTAAAGACGGTTTCCGGTGCATT
GCACGGCGGCTCCGCCCGCATGTCGGACGATAAGCGCCAGAAGGTCAAGGCCATTGCGGAAGAGCTCGGCTACGTGACCA
ACCTTGCGGCGCGTGGCGTGCGACAGGGCTGGCTGCCGCTGGTCGGCGTTGTCTCCGACGGCCTCATCACTTCGCCCTTC
GCCACCGAGATCGTACGTGGCCTCGACGGGGCGGCCCGCAGCGCCGGCATGGCGGTCTTTGCGGTCAACCACCGCAGCGG
CCAATCTATCGGCTCGGTGCTCGACGAGGTGCAGCAGTTCCGGCCGCGCGCCGTTGCTTATGCCGCCATGTACCACAAGG
ATGTCGCGCTGCCGGACAGGTTGGCGGGCGCCGTCGGCGTCATGATCAACTGCCGAGAGGCTACCGGCCGCGTCACCGCG
CTGGTGCCGGACGAAGAGGGCGGCGCGCGGGAGATCGTGCGTTATCTCCTCGTCGCCGGCCGCCGGCGCATTGCCTTCAT
CAACCTGCCAGGCATTCTCGCTGGCACGCTACGCGAGATGGGGTTTCGTGCGGCGCTTGGGGAGGCGGGCATCGACCACG
TCGGGGTGTTTCCGGCGGTGCGCCGCAGCGTCTACAGCGACCGCGCGCCAAGCCTTGTTGCCTCTCATGTGGAGGCGCTT
CTCAAATCCGGTCAACGGCCTGACGCCATCTTGTGCGGCAATGACCGCGTGGCGATGGAAGTCTATGCGGCGCTTGCCCG
CGCCGGCCTTCGCATCCCGGATGATATCGCGGTGGCAAGCTTCGACAACCAGGTCGAGATTGCCTCGCGGCTGGACCCGC
CATTGACGACGATGGCCCTGCCGCACCGCGCCATGGGCCGCCTTGCCATGGAGATCCTCCTGACCGAGCAGCCCGAACCG
CCGCATCTGCATAAACTGCCGTTCCATCTGGTCGAACGGGCATCCGTCTGA

Upstream 100 bases:

>100_bases
GTTCATGGGCAAAAGGCGTGTTCGGTCGTGCAGTGCGCGTAAAAGCCGCTTGACAAAAAGCGTTCTCCGCGACTATTGGG
TAATCGATCACCCAAGGAGG

Downstream 100 bases:

>100_bases
ACATCGAATAGTGCCAAACAGGAGGAGAATACGAAATGAGGATTTTAATGGGTAATCGTTTACTTTCCGCACTCTTAGCG
TCCGCTGCCCTGGTCGCGAC

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Csc operon regulatory protein [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MVRIVAVSLSDIAERAGVSVKTVSGALHGGSARMSDDKRQKVKAIAEELGYVTNLAARGVRQGWLPLVGVVSDGLITSPF
ATEIVRGLDGAARSAGMAVFAVNHRSGQSIGSVLDEVQQFRPRAVAYAAMYHKDVALPDRLAGAVGVMINCREATGRVTA
LVPDEEGGAREIVRYLLVAGRRRIAFINLPGILAGTLREMGFRAALGEAGIDHVGVFPAVRRSVYSDRAPSLVASHVEAL
LKSGQRPDAILCGNDRVAMEVYAALARAGLRIPDDIAVASFDNQVEIASRLDPPLTTMALPHRAMGRLAMEILLTEQPEP
PHLHKLPFHLVERASV

Sequences:

>Translated_336_residues
MVRIVAVSLSDIAERAGVSVKTVSGALHGGSARMSDDKRQKVKAIAEELGYVTNLAARGVRQGWLPLVGVVSDGLITSPF
ATEIVRGLDGAARSAGMAVFAVNHRSGQSIGSVLDEVQQFRPRAVAYAAMYHKDVALPDRLAGAVGVMINCREATGRVTA
LVPDEEGGAREIVRYLLVAGRRRIAFINLPGILAGTLREMGFRAALGEAGIDHVGVFPAVRRSVYSDRAPSLVASHVEAL
LKSGQRPDAILCGNDRVAMEVYAALARAGLRIPDDIAVASFDNQVEIASRLDPPLTTMALPHRAMGRLAMEILLTEQPEP
PHLHKLPFHLVERASV
>Mature_336_residues
MVRIVAVSLSDIAERAGVSVKTVSGALHGGSARMSDDKRQKVKAIAEELGYVTNLAARGVRQGWLPLVGVVSDGLITSPF
ATEIVRGLDGAARSAGMAVFAVNHRSGQSIGSVLDEVQQFRPRAVAYAAMYHKDVALPDRLAGAVGVMINCREATGRVTA
LVPDEEGGAREIVRYLLVAGRRRIAFINLPGILAGTLREMGFRAALGEAGIDHVGVFPAVRRSVYSDRAPSLVASHVEAL
LKSGQRPDAILCGNDRVAMEVYAALARAGLRIPDDIAVASFDNQVEIASRLDPPLTTMALPHRAMGRLAMEILLTEQPEP
PHLHKLPFHLVERASV

Specific function: Repressor for the csc operon. Binds D-fructose as an inducer [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=317, Percent_Identity=28.391167192429, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790369, Length=324, Percent_Identity=29.320987654321, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787948, Length=343, Percent_Identity=27.9883381924198, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788474, Length=346, Percent_Identity=29.1907514450867, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786540, Length=338, Percent_Identity=26.6272189349112, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787906, Length=321, Percent_Identity=26.791277258567, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789202, Length=299, Percent_Identity=27.0903010033445, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35852; Mature: 35852

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRIVAVSLSDIAERAGVSVKTVSGALHGGSARMSDDKRQKVKAIAEELGYVTNLAARGV
CEEEEEECHHHHHHHHCCEEEEECCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQGWLPLVGVVSDGLITSPFATEIVRGLDGAARSAGMAVFAVNHRSGQSIGSVLDEVQQF
HHCCHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHCCEEEEEEECCCCCHHHHHHHHHHHH
RPRAVAYAAMYHKDVALPDRLAGAVGVMINCREATGRVTALVPDEEGGAREIVRYLLVAG
CCHHHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHC
RRRIAFINLPGILAGTLREMGFRAALGEAGIDHVGVFPAVRRSVYSDRAPSLVASHVEAL
CCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHCCCCHHHHHHHHHHH
LKSGQRPDAILCGNDRVAMEVYAALARAGLRIPDDIAVASFDNQVEIASRLDPPLTTMAL
HHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHCCCCHHHHHC
PHRAMGRLAMEILLTEQPEPPHLHKLPFHLVERASV
CHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MVRIVAVSLSDIAERAGVSVKTVSGALHGGSARMSDDKRQKVKAIAEELGYVTNLAARGV
CEEEEEECHHHHHHHHCCEEEEECCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQGWLPLVGVVSDGLITSPFATEIVRGLDGAARSAGMAVFAVNHRSGQSIGSVLDEVQQF
HHCCHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHCCEEEEEEECCCCCHHHHHHHHHHHH
RPRAVAYAAMYHKDVALPDRLAGAVGVMINCREATGRVTALVPDEEGGAREIVRYLLVAG
CCHHHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHC
RRRIAFINLPGILAGTLREMGFRAALGEAGIDHVGVFPAVRRSVYSDRAPSLVASHVEAL
CCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHCCCCHHHHHHHHHHH
LKSGQRPDAILCGNDRVAMEVYAALARAGLRIPDDIAVASFDNQVEIASRLDPPLTTMAL
HHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHCCCCHHHHHC
PHRAMGRLAMEILLTEQPEPPHLHKLPFHLVERASV
CHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA