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The map label for this gene is putA [H]

Identifier: 116249218

GI number: 116249218

Start: 599543

End: 603235

Strand: Direct

Name: putA [H]

Synonym: pRL120554

Alternate gene names: 116249218

Gene position: 599543-603235 (Clockwise)

Preceding gene: 116249217

Following gene: 116249219

Centisome position: 68.91

GC content: 64.72

Gene sequence:

>3693_bases
ATGGACCCCGCCCCCTCCAACGATCCGACCGACGGCGCGCCATTCTCGGCCTTTGCCCCACCGATCCGGCCGCAATCCGA
ACTTCGCCAGGCCATCACGGCAGCCTATCGCCGGCCGGAAACCGAATGCCTGCCGCCGCTCGTTGCCGCAGCGCGCGTCT
CCGAAGCAAAACGCTATGACATTCGCAGCACGGCCCGCAGCCTGATCGAGGCGTTGCGCGCCAAGCACAAGGGGACCGGT
GTCGAAGGGCTGGTGCAGGAATATTCGCTTTCCAGCCAGGAAGGCGTGGCGCTCATGTGCCTCGCCGAAGCGCTGCTGCG
CATTCCCGATACCGAAACCCGGGACGCGCTGATCCGCGACAAGATCGCCGAGGGTAACTGGACCTCCCATATCGGCGGCG
GAAAATCCATGTTCGTCAATGCCGCCACCTGGGGCCTCGTCGTCACCGGCAAGCTCACCTCGACGGTCAACGACCGAAGC
CTGTCGGCAGCGCTGACGCGGCTGATTGCGCGCGCCGGCGAGCCGGTCATCCGTCGCGGCGTCGATATGGCGATGCGCAT
GATGGGCGAGCAGTTCGTCACCGGCGAAACGATCGCAGAGGCGCTGAAACGCGCCCGGCCGCTGGAAGCGCGCGGCTTCC
GCTATTCCTACGACATGCTGGGCGAGGCAGCGACGACGGGCGCTGATGCCGAGCGTTATTACCGGGATTACGAAAAGGCG
ATCCACGCCATCGGCAAGGCGTCGGACGGGCGCGGCATCTATGACGGCCCGGGCATATCGATCAAGCTTTCGGCCCTGCA
TCCCCGTTACGTGAGGTCGCAGGCCGGCCGGGTGATGAGCGAGCTGCTGCCGAAGGTCAAGGCGCTGGCCGTTCTCGCCA
AGACCTATGATATCGGCCTCAATATTGACGCGGAGGAGGCCGATCGGCTGGAGCTTTCGCTCGATCTCCTCGAGGAGCTT
TGCTTTGCCCCTGATCTTGCCGGATGGAACGGGCTGGGCTTCGTCGTGCAGGCCTATGGCAAGCGCTGCCCCTTCGTCCT
CGACTACATCATCGATCTCGCACGCCGCTCCGGGCGCCGGGTCATGGTCCGTCTCGTCAAGGGCGCTTATTGGGATGCGG
AGATCAAGCGTGCCCAGCTTGACGGTCTCGACGACTATCCGGTCTATACCCGCAAGATCTTCACCGACGTCGCCTACGTC
GCCTGCGCGCGCAAGCTGCTCGATGCTCCGGATGCGGTCTTCCCGCAATTTGCCACCCATAATGCGCAGACGCTCGCCAC
GATCTATCGTCTGGCGGGCCCTGATTTCACCGTCGGCAAATACGAGTTCCAATGCCTGCATGGCATGGGCGAACCTCTCT
ACGACGAGGTTGTCGGAAAGGAAAAGCTGGACCGGCCCTGCCGGATTTATGCGCCTGTGGGAACGCATGAGACGCTGCTC
GCCTATCTGGTTCGGCGTCTTCTGGAAAATGGCGCCAATTCCTCCTTCGTGCACCGCATCTCCGATCCGAATGTCTCGGT
CGAGGCGCTGATCGCCGATCCCGCCGAAATCGTCGCAGCCATGCCTGTCGTTGGCGCGCCGCACGCGCAGATCGCCTCGC
CGCGGGCACTTTACGGCAATGCCCGGGCCAATTCCGATGGTCTCGATCTCTCGAACGAGGCCACCCTTTCGGATTTGGCT
GATGCGCTCATCTCCACGGCTGCTGCCCCGTGGCATGCGCTTCCCCTCCTTGCCGACGGCTCTACGGATGGGGTGACGCG
CGATGTTCTCAATCCTGCCGATCACCGGGATGTCGTCGGCACGGTGACCGAAGTGAAGGTCGAGGAGGCAGCGCGTATCG
TTCGCATGGCTGCGGAGCATGCGCCGCAATGGGCGGCCGTGCCGCCGGCCGAGCGTGCCGCCTGCCTGGAGCGGGCGGCC
GATATCATGCAGGCCCGCATCAAGGTGCTGATGGGCATTGTCATGCGCGAGGCCGGCAAATCCGCGGCCAATGCCGTCGG
CGAGGTGCGTGAGGCCATCGACTTCCTGCGCTACTACGCCGAACAGGCGCGCAAGACGCTGGGCCCCTCGCATGCGCCCC
TCGGCCCGATCGTCTGCATCAGCCCGTGGAATTTTCCGCTGGCGATTTTCACCGGACAGGTCGCCGCAGCCTTGGTGGCC
GGCAATCCCGTGCTTGCCAAACCTGCCGGCGTCACGCCGATTATCGCTTCGGAGAGCGTCAAGATCCTTCACGAGGCGGG
CGTGCCTGTCGGTGCCCTGCAGTTCGTCCCCGGCAGCGGCCGTCTCGGCGCCGGTATGGTCGGGGCGGAGGAAACGGCAG
GCGTTATGTTTACCGGGTCGACCGAAGTTGCCCGCATGATCCAGGCGCAGCTGGCGGAACGGCTGTCGGTGAGCGGCAAG
CCGATTCCGCTGATTGCCGAAACCGGCGGCCAGAACGGCATGATCGTCGACTCCTCGGCTTTGGCCGAGCAGGTGGTGGC
CGACGTCATCGCGTCAGCTTTCGACAGCGCCGGTCAGCGCTGCTCGGCGCTCAGGGTTCTCTGCGTTCAGGACGATGTCG
CCGACAGGACTCTCGCCATGCTGAAGGGCGCCTTCCGCGAGCTGACGATCGGCCGTACCGATCGCCTGAGCATCGATGTC
GGCCCGGTCATCAACGACAGCGCAAAGGCGGAGATCGACCAGCATATCGAGCATATGCGCGGCTTGGGCCGCAAGGTGGA
TCAGCTGCCGCTGCCCGAAAGTGCCGCGGCGGGAACCTTCGTTCCGCCCACAATCATCGAAATCAAGTCCCTGTCGGACC
TGACGAAGGAGATCTTCGGACCGGTTCTGCATGTCGTCCGCTTCAAGCGAAACGGGCTCGACCGTCTGATCGACGACATC
AACGCATCGGGTTATGGTCTCACATTCGGGCTTCACACCCGGCTTGATGAGACGATCGCGCATGTGACCAGCCGCATCAA
GGCCGGAAACCTTTACGTCAACCGGAACATCATCGGCGCCGTCGTCGGCGTGCAGCCGTTCGGCGGCCGCGGCCTGTCGG
GAACCGGTCCGAAGGCCGGCGGTCCGCTCTATATCGGCCGGCTGGTGCAGCGTGCGCCCGTGCCGCCGCAGCAGGATTCC
GTCCATACGGACCTCGCCCTTCGTGACTACATCGTCTGGCTCGACAAGAAGGGCCTGTCGGGCGAGGGGGAAGTGGCGCG
TGGATATGCGAGCCGCTCGGCGCTCGGGCTCGAACGCGAACTCACCGGTCCGGTGGGCGAGCTCAATCTCTACGCGCTCC
ATCCCCGCGGTCGTATTCTCCTCGTGCCGCAGACCGAAGGCGGGCTTCATCGCCAGATTGCCGCAGCCCTTTCGACCGGC
AACCACATCGTCGTGGACGCGGGTTCCCTATCGAAGTCAGTCCTGGCAGACCTTCCGGCGGCTGTCGCCGGCCGGATCTC
CTGGACCTCGGATTGGGAAAAGGACGGGCCGTTCTCCGGCGCGCTCGTCGAAGGGGATCGCGACAGGGTTCTCGCCGTCA
ATCAGAAGATTGCTCACCTGCCCGGTCCGCTGCTGCTGGTCCAGGCCGCGACGAGCGAGGAACTGGCGAGCGATCCCGAA
GCCTATTGCCTCAACTGGTTGCTGGAGGAGGTGTCGACGTCGATCAACACCGCGGCTGCCGGCGGCAATGCAAGCCTGAT
GGCCATCGGCTGA

Upstream 100 bases:

>100_bases
AGCTTGCACGGACGATGCGCAGTGGGACGACGAGCCCGGCATCTCGTTCATCCGTTAAACCAGATATCGATTGATAGGTA
CCTTCATGTTGAACGCAGCG

Downstream 100 bases:

>100_bases
GTAACAGGACGAGGGCGCAGAAAATGCGCCCCCGAAACTCTAGACGGAAAAGAGGCCCTCTTCCCGGAATTCAATCTCGC
TTCCTCGGCCTATACGGCGT

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1230; Mature: 1230

Protein sequence:

>1230_residues
MDPAPSNDPTDGAPFSAFAPPIRPQSELRQAITAAYRRPETECLPPLVAAARVSEAKRYDIRSTARSLIEALRAKHKGTG
VEGLVQEYSLSSQEGVALMCLAEALLRIPDTETRDALIRDKIAEGNWTSHIGGGKSMFVNAATWGLVVTGKLTSTVNDRS
LSAALTRLIARAGEPVIRRGVDMAMRMMGEQFVTGETIAEALKRARPLEARGFRYSYDMLGEAATTGADAERYYRDYEKA
IHAIGKASDGRGIYDGPGISIKLSALHPRYVRSQAGRVMSELLPKVKALAVLAKTYDIGLNIDAEEADRLELSLDLLEEL
CFAPDLAGWNGLGFVVQAYGKRCPFVLDYIIDLARRSGRRVMVRLVKGAYWDAEIKRAQLDGLDDYPVYTRKIFTDVAYV
ACARKLLDAPDAVFPQFATHNAQTLATIYRLAGPDFTVGKYEFQCLHGMGEPLYDEVVGKEKLDRPCRIYAPVGTHETLL
AYLVRRLLENGANSSFVHRISDPNVSVEALIADPAEIVAAMPVVGAPHAQIASPRALYGNARANSDGLDLSNEATLSDLA
DALISTAAAPWHALPLLADGSTDGVTRDVLNPADHRDVVGTVTEVKVEEAARIVRMAAEHAPQWAAVPPAERAACLERAA
DIMQARIKVLMGIVMREAGKSAANAVGEVREAIDFLRYYAEQARKTLGPSHAPLGPIVCISPWNFPLAIFTGQVAAALVA
GNPVLAKPAGVTPIIASESVKILHEAGVPVGALQFVPGSGRLGAGMVGAEETAGVMFTGSTEVARMIQAQLAERLSVSGK
PIPLIAETGGQNGMIVDSSALAEQVVADVIASAFDSAGQRCSALRVLCVQDDVADRTLAMLKGAFRELTIGRTDRLSIDV
GPVINDSAKAEIDQHIEHMRGLGRKVDQLPLPESAAAGTFVPPTIIEIKSLSDLTKEIFGPVLHVVRFKRNGLDRLIDDI
NASGYGLTFGLHTRLDETIAHVTSRIKAGNLYVNRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYIGRLVQRAPVPPQQDS
VHTDLALRDYIVWLDKKGLSGEGEVARGYASRSALGLERELTGPVGELNLYALHPRGRILLVPQTEGGLHRQIAAALSTG
NHIVVDAGSLSKSVLADLPAAVAGRISWTSDWEKDGPFSGALVEGDRDRVLAVNQKIAHLPGPLLLVQAATSEELASDPE
AYCLNWLLEEVSTSINTAAAGGNASLMAIG

Sequences:

>Translated_1230_residues
MDPAPSNDPTDGAPFSAFAPPIRPQSELRQAITAAYRRPETECLPPLVAAARVSEAKRYDIRSTARSLIEALRAKHKGTG
VEGLVQEYSLSSQEGVALMCLAEALLRIPDTETRDALIRDKIAEGNWTSHIGGGKSMFVNAATWGLVVTGKLTSTVNDRS
LSAALTRLIARAGEPVIRRGVDMAMRMMGEQFVTGETIAEALKRARPLEARGFRYSYDMLGEAATTGADAERYYRDYEKA
IHAIGKASDGRGIYDGPGISIKLSALHPRYVRSQAGRVMSELLPKVKALAVLAKTYDIGLNIDAEEADRLELSLDLLEEL
CFAPDLAGWNGLGFVVQAYGKRCPFVLDYIIDLARRSGRRVMVRLVKGAYWDAEIKRAQLDGLDDYPVYTRKIFTDVAYV
ACARKLLDAPDAVFPQFATHNAQTLATIYRLAGPDFTVGKYEFQCLHGMGEPLYDEVVGKEKLDRPCRIYAPVGTHETLL
AYLVRRLLENGANSSFVHRISDPNVSVEALIADPAEIVAAMPVVGAPHAQIASPRALYGNARANSDGLDLSNEATLSDLA
DALISTAAAPWHALPLLADGSTDGVTRDVLNPADHRDVVGTVTEVKVEEAARIVRMAAEHAPQWAAVPPAERAACLERAA
DIMQARIKVLMGIVMREAGKSAANAVGEVREAIDFLRYYAEQARKTLGPSHAPLGPIVCISPWNFPLAIFTGQVAAALVA
GNPVLAKPAGVTPIIASESVKILHEAGVPVGALQFVPGSGRLGAGMVGAEETAGVMFTGSTEVARMIQAQLAERLSVSGK
PIPLIAETGGQNGMIVDSSALAEQVVADVIASAFDSAGQRCSALRVLCVQDDVADRTLAMLKGAFRELTIGRTDRLSIDV
GPVINDSAKAEIDQHIEHMRGLGRKVDQLPLPESAAAGTFVPPTIIEIKSLSDLTKEIFGPVLHVVRFKRNGLDRLIDDI
NASGYGLTFGLHTRLDETIAHVTSRIKAGNLYVNRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYIGRLVQRAPVPPQQDS
VHTDLALRDYIVWLDKKGLSGEGEVARGYASRSALGLERELTGPVGELNLYALHPRGRILLVPQTEGGLHRQIAAALSTG
NHIVVDAGSLSKSVLADLPAAVAGRISWTSDWEKDGPFSGALVEGDRDRVLAVNQKIAHLPGPLLLVQAATSEELASDPE
AYCLNWLLEEVSTSINTAAAGGNASLMAIG
>Mature_1230_residues
MDPAPSNDPTDGAPFSAFAPPIRPQSELRQAITAAYRRPETECLPPLVAAARVSEAKRYDIRSTARSLIEALRAKHKGTG
VEGLVQEYSLSSQEGVALMCLAEALLRIPDTETRDALIRDKIAEGNWTSHIGGGKSMFVNAATWGLVVTGKLTSTVNDRS
LSAALTRLIARAGEPVIRRGVDMAMRMMGEQFVTGETIAEALKRARPLEARGFRYSYDMLGEAATTGADAERYYRDYEKA
IHAIGKASDGRGIYDGPGISIKLSALHPRYVRSQAGRVMSELLPKVKALAVLAKTYDIGLNIDAEEADRLELSLDLLEEL
CFAPDLAGWNGLGFVVQAYGKRCPFVLDYIIDLARRSGRRVMVRLVKGAYWDAEIKRAQLDGLDDYPVYTRKIFTDVAYV
ACARKLLDAPDAVFPQFATHNAQTLATIYRLAGPDFTVGKYEFQCLHGMGEPLYDEVVGKEKLDRPCRIYAPVGTHETLL
AYLVRRLLENGANSSFVHRISDPNVSVEALIADPAEIVAAMPVVGAPHAQIASPRALYGNARANSDGLDLSNEATLSDLA
DALISTAAAPWHALPLLADGSTDGVTRDVLNPADHRDVVGTVTEVKVEEAARIVRMAAEHAPQWAAVPPAERAACLERAA
DIMQARIKVLMGIVMREAGKSAANAVGEVREAIDFLRYYAEQARKTLGPSHAPLGPIVCISPWNFPLAIFTGQVAAALVA
GNPVLAKPAGVTPIIASESVKILHEAGVPVGALQFVPGSGRLGAGMVGAEETAGVMFTGSTEVARMIQAQLAERLSVSGK
PIPLIAETGGQNGMIVDSSALAEQVVADVIASAFDSAGQRCSALRVLCVQDDVADRTLAMLKGAFRELTIGRTDRLSIDV
GPVINDSAKAEIDQHIEHMRGLGRKVDQLPLPESAAAGTFVPPTIIEIKSLSDLTKEIFGPVLHVVRFKRNGLDRLIDDI
NASGYGLTFGLHTRLDETIAHVTSRIKAGNLYVNRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYIGRLVQRAPVPPQQDS
VHTDLALRDYIVWLDKKGLSGEGEVARGYASRSALGLERELTGPVGELNLYALHPRGRILLVPQTEGGLHRQIAAALSTG
NHIVVDAGSLSKSVLADLPAAVAGRISWTSDWEKDGPFSGALVEGDRDRVLAVNQKIAHLPGPLLLVQAATSEELASDPE
AYCLNWLLEEVSTSINTAAAGGNASLMAIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source, and also functions as a transcriptional repressor of its own gene [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=488, Percent_Identity=30.9426229508197, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI25777734, Length=488, Percent_Identity=30.9426229508197, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI238859541, Length=488, Percent_Identity=30.9426229508197, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI12007648, Length=435, Percent_Identity=28.735632183908, Blast_Score=156, Evalue=1e-37,
Organism=Homo sapiens, GI21361176, Length=468, Percent_Identity=29.0598290598291, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI21614513, Length=423, Percent_Identity=28.6052009456265, Blast_Score=147, Evalue=5e-35,
Organism=Homo sapiens, GI25777724, Length=469, Percent_Identity=28.3582089552239, Blast_Score=147, Evalue=5e-35,
Organism=Homo sapiens, GI25777732, Length=463, Percent_Identity=28.7257019438445, Blast_Score=145, Evalue=3e-34,
Organism=Homo sapiens, GI153266822, Length=471, Percent_Identity=27.6008492569002, Blast_Score=144, Evalue=5e-34,
Organism=Homo sapiens, GI25777728, Length=418, Percent_Identity=28.9473684210526, Blast_Score=137, Evalue=8e-32,
Organism=Homo sapiens, GI238814322, Length=470, Percent_Identity=26.1702127659574, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI25777730, Length=476, Percent_Identity=27.5210084033613, Blast_Score=134, Evalue=7e-31,
Organism=Homo sapiens, GI188035924, Length=456, Percent_Identity=27.1929824561404, Blast_Score=132, Evalue=3e-30,
Organism=Homo sapiens, GI310128093, Length=456, Percent_Identity=27.1929824561404, Blast_Score=132, Evalue=3e-30,
Organism=Homo sapiens, GI310128103, Length=456, Percent_Identity=27.1929824561404, Blast_Score=131, Evalue=4e-30,
Organism=Homo sapiens, GI4507229, Length=419, Percent_Identity=26.9689737470167, Blast_Score=130, Evalue=7e-30,
Organism=Homo sapiens, GI25952152, Length=429, Percent_Identity=28.2051282051282, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI115387104, Length=463, Percent_Identity=26.9978401727862, Blast_Score=125, Evalue=3e-28,
Organism=Homo sapiens, GI25777721, Length=432, Percent_Identity=26.1574074074074, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI11095441, Length=429, Percent_Identity=27.039627039627, Blast_Score=115, Evalue=3e-25,
Organism=Homo sapiens, GI25777726, Length=468, Percent_Identity=25.8547008547009, Blast_Score=111, Evalue=4e-24,
Organism=Homo sapiens, GI310128091, Length=394, Percent_Identity=27.6649746192893, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI310128087, Length=273, Percent_Identity=29.3040293040293, Blast_Score=104, Evalue=4e-22,
Organism=Homo sapiens, GI4502043, Length=412, Percent_Identity=25.4854368932039, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI238814371, Length=412, Percent_Identity=25.4854368932039, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI71773324, Length=330, Percent_Identity=25.1515151515152, Blast_Score=94, Evalue=9e-19,
Organism=Homo sapiens, GI206597441, Length=332, Percent_Identity=26.2048192771084, Blast_Score=90, Evalue=2e-17,
Organism=Homo sapiens, GI206597439, Length=332, Percent_Identity=26.2048192771084, Blast_Score=90, Evalue=2e-17,
Organism=Homo sapiens, GI22907049, Length=332, Percent_Identity=26.2048192771084, Blast_Score=90, Evalue=2e-17,
Organism=Homo sapiens, GI310128099, Length=221, Percent_Identity=28.5067873303167, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI310128101, Length=221, Percent_Identity=28.5067873303167, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI73695881, Length=334, Percent_Identity=24.5508982035928, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI73695879, Length=334, Percent_Identity=24.5508982035928, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI310128089, Length=329, Percent_Identity=26.4437689969605, Blast_Score=82, Evalue=4e-15,
Organism=Homo sapiens, GI301500698, Length=281, Percent_Identity=27.0462633451957, Blast_Score=81, Evalue=8e-15,
Organism=Homo sapiens, GI4557303, Length=336, Percent_Identity=23.2142857142857, Blast_Score=78, Evalue=6e-14,
Organism=Homo sapiens, GI73466520, Length=336, Percent_Identity=23.2142857142857, Blast_Score=78, Evalue=7e-14,
Organism=Homo sapiens, GI310128095, Length=245, Percent_Identity=25.7142857142857, Blast_Score=69, Evalue=3e-11,
Organism=Escherichia coli, GI1787250, Length=1264, Percent_Identity=57.1993670886076, Blast_Score=1388, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=455, Percent_Identity=31.2087912087912, Blast_Score=179, Evalue=9e-46,
Organism=Escherichia coli, GI1788042, Length=427, Percent_Identity=31.1475409836066, Blast_Score=165, Evalue=1e-41,
Organism=Escherichia coli, GI1787684, Length=456, Percent_Identity=29.1666666666667, Blast_Score=155, Evalue=2e-38,
Organism=Escherichia coli, GI1787715, Length=462, Percent_Identity=28.1385281385281, Blast_Score=142, Evalue=2e-34,
Organism=Escherichia coli, GI87081896, Length=467, Percent_Identity=27.4089935760171, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI1787558, Length=413, Percent_Identity=30.9927360774818, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI1786504, Length=470, Percent_Identity=28.0851063829787, Blast_Score=127, Evalue=4e-30,
Organism=Escherichia coli, GI87082295, Length=428, Percent_Identity=27.5700934579439, Blast_Score=111, Evalue=3e-25,
Organism=Escherichia coli, GI87081926, Length=396, Percent_Identity=25.2525252525253, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1787653, Length=258, Percent_Identity=24.031007751938, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534447, Length=489, Percent_Identity=29.2433537832311, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI115534176, Length=452, Percent_Identity=30.0884955752212, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17562198, Length=462, Percent_Identity=30.0865800865801, Blast_Score=147, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI115532534, Length=400, Percent_Identity=30.25, Blast_Score=147, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17534119, Length=461, Percent_Identity=27.765726681128, Blast_Score=144, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI25144435, Length=461, Percent_Identity=29.7180043383948, Blast_Score=144, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI133930964, Length=463, Percent_Identity=27.2138228941685, Blast_Score=143, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI32564736, Length=412, Percent_Identity=30.3398058252427, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25143874, Length=428, Percent_Identity=26.8691588785047, Blast_Score=133, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI25143876, Length=428, Percent_Identity=26.8691588785047, Blast_Score=132, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32564151, Length=414, Percent_Identity=27.536231884058, Blast_Score=130, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI71995606, Length=458, Percent_Identity=27.292576419214, Blast_Score=117, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71986308, Length=457, Percent_Identity=26.9146608315098, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17551164, Length=457, Percent_Identity=25.164113785558, Blast_Score=114, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71995613, Length=415, Percent_Identity=26.7469879518072, Blast_Score=108, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71990744, Length=318, Percent_Identity=27.6729559748428, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25146391, Length=330, Percent_Identity=25.4545454545455, Blast_Score=90, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI32566756, Length=330, Percent_Identity=25.4545454545455, Blast_Score=90, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI25146394, Length=330, Percent_Identity=25.4545454545455, Blast_Score=90, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17564084, Length=333, Percent_Identity=26.4264264264264, Blast_Score=89, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321826, Length=502, Percent_Identity=28.4860557768924, Blast_Score=169, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6320917, Length=454, Percent_Identity=30.3964757709251, Blast_Score=169, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6325196, Length=462, Percent_Identity=30.952380952381, Blast_Score=164, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6324950, Length=459, Percent_Identity=29.1938997821351, Blast_Score=154, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6323822, Length=503, Percent_Identity=28.6282306163022, Blast_Score=152, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6323821, Length=499, Percent_Identity=29.6593186372746, Blast_Score=150, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6319478, Length=455, Percent_Identity=27.032967032967, Blast_Score=143, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6323757, Length=325, Percent_Identity=24, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24668425, Length=463, Percent_Identity=31.317494600432, Blast_Score=178, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24668417, Length=463, Percent_Identity=31.317494600432, Blast_Score=178, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24668413, Length=463, Percent_Identity=31.317494600432, Blast_Score=178, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281362580, Length=461, Percent_Identity=29.7180043383948, Blast_Score=174, Evalue=4e-43,
Organism=Drosophila melanogaster, GI62472918, Length=461, Percent_Identity=29.7180043383948, Blast_Score=174, Evalue=4e-43,
Organism=Drosophila melanogaster, GI62472926, Length=461, Percent_Identity=29.7180043383948, Blast_Score=174, Evalue=4e-43,
Organism=Drosophila melanogaster, GI62472936, Length=461, Percent_Identity=29.7180043383948, Blast_Score=174, Evalue=4e-43,
Organism=Drosophila melanogaster, GI21356737, Length=461, Percent_Identity=29.7180043383948, Blast_Score=174, Evalue=4e-43,
Organism=Drosophila melanogaster, GI20129399, Length=469, Percent_Identity=28.1449893390192, Blast_Score=156, Evalue=8e-38,
Organism=Drosophila melanogaster, GI24650465, Length=458, Percent_Identity=27.9475982532751, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28574525, Length=429, Percent_Identity=28.6713286713287, Blast_Score=136, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24585660, Length=464, Percent_Identity=26.5086206896552, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571806, Length=446, Percent_Identity=28.2511210762332, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571802, Length=446, Percent_Identity=28.2511210762332, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571800, Length=446, Percent_Identity=28.2511210762332, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571798, Length=446, Percent_Identity=28.2511210762332, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571796, Length=446, Percent_Identity=28.2511210762332, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571794, Length=446, Percent_Identity=28.2511210762332, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24666674, Length=448, Percent_Identity=27.2321428571429, Blast_Score=128, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24638876, Length=375, Percent_Identity=28.5333333333333, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24638878, Length=375, Percent_Identity=28.5333333333333, Blast_Score=97, Evalue=7e-20,
Organism=Drosophila melanogaster, GI281360299, Length=334, Percent_Identity=27.5449101796407, Blast_Score=94, Evalue=8e-19,
Organism=Drosophila melanogaster, GI281360297, Length=334, Percent_Identity=27.5449101796407, Blast_Score=94, Evalue=8e-19,
Organism=Drosophila melanogaster, GI281360295, Length=334, Percent_Identity=27.5449101796407, Blast_Score=94, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24586250, Length=334, Percent_Identity=27.5449101796407, Blast_Score=94, Evalue=8e-19,
Organism=Drosophila melanogaster, GI281360301, Length=334, Percent_Identity=27.5449101796407, Blast_Score=93, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45552499, Length=334, Percent_Identity=26.3473053892216, Blast_Score=91, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281360303, Length=334, Percent_Identity=26.3473053892216, Blast_Score=90, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 131448; Mature: 131448

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPAPSNDPTDGAPFSAFAPPIRPQSELRQAITAAYRRPETECLPPLVAAARVSEAKRYD
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHH
IRSTARSLIEALRAKHKGTGVEGLVQEYSLSSQEGVALMCLAEALLRIPDTETRDALIRD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
KIAEGNWTSHIGGGKSMFVNAATWGLVVTGKLTSTVNDRSLSAALTRLIARAGEPVIRRG
HHCCCCCCCCCCCCCEEEEEEEEEEEEEECCHHCCCCHHHHHHHHHHHHHHCCCHHHHHH
VDMAMRMMGEQFVTGETIAEALKRARPLEARGFRYSYDMLGEAATTGADAERYYRDYEKA
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHH
IHAIGKASDGRGIYDGPGISIKLSALHPRYVRSQAGRVMSELLPKVKALAVLAKTYDIGL
HHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NIDAEEADRLELSLDLLEELCFAPDLAGWNGLGFVVQAYGKRCPFVLDYIIDLARRSGRR
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCHH
VMVRLVKGAYWDAEIKRAQLDGLDDYPVYTRKIFTDVAYVACARKLLDAPDAVFPQFATH
HHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHCC
NAQTLATIYRLAGPDFTVGKYEFQCLHGMGEPLYDEVVGKEKLDRPCRIYAPVGTHETLL
CHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHCHHHCCCCEEEEECCCCHHHHH
AYLVRRLLENGANSSFVHRISDPNVSVEALIADPAEIVAAMPVVGAPHAQIASPRALYGN
HHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCHHHHHHHCCCCCCCCHHHCCCHHHCCC
ARANSDGLDLSNEATLSDLADALISTAAAPWHALPLLADGSTDGVTRDVLNPADHRDVVG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHCCCCCCCHHHH
TVTEVKVEEAARIVRMAAEHAPQWAAVPPAERAACLERAADIMQARIKVLMGIVMREAGK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SAANAVGEVREAIDFLRYYAEQARKTLGPSHAPLGPIVCISPWNFPLAIFTGQVAAALVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHC
GNPVLAKPAGVTPIIASESVKILHEAGVPVGALQFVPGSGRLGAGMVGAEETAGVMFTGS
CCCCEECCCCCCCEECCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECC
TEVARMIQAQLAERLSVSGKPIPLIAETGGQNGMIVDSSALAEQVVADVIASAFDSAGQR
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
CSALRVLCVQDDVADRTLAMLKGAFRELTIGRTDRLSIDVGPVINDSAKAEIDQHIEHMR
HHHHEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
GLGRKVDQLPLPESAAAGTFVPPTIIEIKSLSDLTKEIFGPVLHVVRFKRNGLDRLIDDI
HHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
NASGYGLTFGLHTRLDETIAHVTSRIKAGNLYVNRNIIGAVVGVQPFGGRGLSGTGPKAG
CCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCCCCCCCCCCC
GPLYIGRLVQRAPVPPQQDSVHTDLALRDYIVWLDKKGLSGEGEVARGYASRSALGLERE
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHCCCHHH
LTGPVGELNLYALHPRGRILLVPQTEGGLHRQIAAALSTGNHIVVDAGSLSKSVLADLPA
CCCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCH
AVAGRISWTSDWEKDGPFSGALVEGDRDRVLAVNQKIAHLPGPLLLVQAATSEELASDPE
HHHCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCHHHHCCCCEEEEEECCHHHHHCCHH
AYCLNWLLEEVSTSINTAAAGGNASLMAIG
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MDPAPSNDPTDGAPFSAFAPPIRPQSELRQAITAAYRRPETECLPPLVAAARVSEAKRYD
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHH
IRSTARSLIEALRAKHKGTGVEGLVQEYSLSSQEGVALMCLAEALLRIPDTETRDALIRD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
KIAEGNWTSHIGGGKSMFVNAATWGLVVTGKLTSTVNDRSLSAALTRLIARAGEPVIRRG
HHCCCCCCCCCCCCCEEEEEEEEEEEEEECCHHCCCCHHHHHHHHHHHHHHCCCHHHHHH
VDMAMRMMGEQFVTGETIAEALKRARPLEARGFRYSYDMLGEAATTGADAERYYRDYEKA
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHH
IHAIGKASDGRGIYDGPGISIKLSALHPRYVRSQAGRVMSELLPKVKALAVLAKTYDIGL
HHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NIDAEEADRLELSLDLLEELCFAPDLAGWNGLGFVVQAYGKRCPFVLDYIIDLARRSGRR
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCHH
VMVRLVKGAYWDAEIKRAQLDGLDDYPVYTRKIFTDVAYVACARKLLDAPDAVFPQFATH
HHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHCC
NAQTLATIYRLAGPDFTVGKYEFQCLHGMGEPLYDEVVGKEKLDRPCRIYAPVGTHETLL
CHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHCHHHCCCCEEEEECCCCHHHHH
AYLVRRLLENGANSSFVHRISDPNVSVEALIADPAEIVAAMPVVGAPHAQIASPRALYGN
HHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCHHHHHHHCCCCCCCCHHHCCCHHHCCC
ARANSDGLDLSNEATLSDLADALISTAAAPWHALPLLADGSTDGVTRDVLNPADHRDVVG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHCCCCCCCHHHH
TVTEVKVEEAARIVRMAAEHAPQWAAVPPAERAACLERAADIMQARIKVLMGIVMREAGK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SAANAVGEVREAIDFLRYYAEQARKTLGPSHAPLGPIVCISPWNFPLAIFTGQVAAALVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHC
GNPVLAKPAGVTPIIASESVKILHEAGVPVGALQFVPGSGRLGAGMVGAEETAGVMFTGS
CCCCEECCCCCCCEECCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECC
TEVARMIQAQLAERLSVSGKPIPLIAETGGQNGMIVDSSALAEQVVADVIASAFDSAGQR
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
CSALRVLCVQDDVADRTLAMLKGAFRELTIGRTDRLSIDVGPVINDSAKAEIDQHIEHMR
HHHHEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
GLGRKVDQLPLPESAAAGTFVPPTIIEIKSLSDLTKEIFGPVLHVVRFKRNGLDRLIDDI
HHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
NASGYGLTFGLHTRLDETIAHVTSRIKAGNLYVNRNIIGAVVGVQPFGGRGLSGTGPKAG
CCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCCCCCCCCCCC
GPLYIGRLVQRAPVPPQQDSVHTDLALRDYIVWLDKKGLSGEGEVARGYASRSALGLERE
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHCCCHHH
LTGPVGELNLYALHPRGRILLVPQTEGGLHRQIAAALSTGNHIVVDAGSLSKSVLADLPA
CCCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCH
AVAGRISWTSDWEKDGPFSGALVEGDRDRVLAVNQKIAHLPGPLLLVQAATSEELASDPE
HHHCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCHHHHCCCCEEEEEECCHHHHHCCHH
AYCLNWLLEEVSTSINTAAAGGNASLMAIG
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9004223; 10715000 [H]