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The map label for this gene is codA [H]

Identifier: 116248977

GI number: 116248977

Start: 326139

End: 327452

Strand: Direct

Name: codA [H]

Synonym: pRL120308

Alternate gene names: 116248977

Gene position: 326139-327452 (Clockwise)

Preceding gene: 116248976

Following gene: 116248978

Centisome position: 37.49

GC content: 64.46

Gene sequence:

>1314_bases
ATGACCTATTCCTTCATATCCCCGCCGAATGCTGCCCGGTTCGTGCTGAGCAATGCGACAGTGCCCGCCGTCACCGTCGA
GCATATCGACGTGCCGGTCACAGAAGGGCTGGCCACAGTCGATATCGTCATCAGCGACGGCATGATTGCCGCCATCCGGC
CGGCCGGCGCCGCACCCGCCGATTATGCCAGGACCGATCTCAGGGACGGAATGGTCTGGCCGTGCTTTGCCGATATCCAT
ACCCATCTCGACAAGGGCCATATCTGGCCGCGCCAGGCCAATCCCGACGGTAGCTTCATGGGTGCGCTCGATGCCGTCAG
GGCCGACCGTGAAGCCAACTGGTCGGCGGCAGACGTCAAACGGCGCATGGAATTCTCGCTCCGCTCCGCCCATGCCCATG
GCACCAGCCTGATCCGCACGCACCTCGATTCGCTTGCGCCCCAGCATCGCATCTCCTTCGAGGTCTTTGCCGAAATCCGG
GATGCCTGGAAAGACAGGATCGCACTGCAAGCGGTCGCCCTCTTCCCGCTGGATGCCATGGCAGACAGCGCCTTCTTTGC
CGATCTCGTCACAACAATCCGACAGACCGGCGGCCTGCTTGGCGGCGTCACCCGGATGGGGCCGGAGCTTGTCTGGCAGC
TCGACATGCTCTTCAGGACTGCCGCAGAGCATGGCCTGGATATCGATCTGCATGTCGACGAGACGGATGATCGCGGTGCG
GAAACACTGAAGGCAATTGCCGAGGCCGTGCTGCGCAACGGGTTCGAGGGCAAGGTGACCGCCGGCCATTGCTGCTCGCT
CGCCCGCCAGGACGAAGACACCGCCGCGCGCACCGTCGAGTTGGTCGCCAAGGCAGGTATCGCGGTCATCGCGCTGCCGA
TGTGCAACATGTATCTGCAGGACCGCTATCCCGGCCGCACCCCGCGCTGGCGCGGTGTCACCCTGTTCAAGGAGCTGGTC
GCCGCCGGTGTCGCGACCGCGGTCGCATCCGACAATACCCGTGATCCCTTCTATGCCTATGGCGATCTCGATCCGGTGGA
GGTCTTCCGCGAGGCCGTGCGGATTCTGCATCTCGATCACCCGCTCGATACCGCCGCCCGTGTCGTCACCACCTCGCCCG
CCGCCATCGTCGGGCGACCGGACAAGGGCCGTATCGCCGCCGGCGATCCCGCCGATCTCGTGCTCTTCAGCGCACGGCGC
TGGAGTGAATTCCTGTCCCGTCCGCAGTCTGACCGCGTCGTGCTTCGCCGCGGCAAGGTGATCGACCGCAGTCTGCCGGA
TTACCGTGAACTCGATAGTGTCGTTGGAGCCTGA

Upstream 100 bases:

>100_bases
TGCTCTCCATGCTTGGCGTAGCGATCTTCGGCCTCACCACACTCATCGCCTGGCTGAGCCTCCACCGCTGGCATGAGAGC
AGCATCAAACGGGAAAACTG

Downstream 100 bases:

>100_bases
CATGGCCGATTATCAGAAGATCAAAAAGGACCTCGAAGGCATCGCTGTCGAGGACAATCCGGCGCTGGTTCGCCAGAAGA
GCCGGGATTTCTATTGGTAC

Product: cytosine deaminase-like protein

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTYSFISPPNAARFVLSNATVPAVTVEHIDVPVTEGLATVDIVISDGMIAAIRPAGAAPADYARTDLRDGMVWPCFADIH
THLDKGHIWPRQANPDGSFMGALDAVRADREANWSAADVKRRMEFSLRSAHAHGTSLIRTHLDSLAPQHRISFEVFAEIR
DAWKDRIALQAVALFPLDAMADSAFFADLVTTIRQTGGLLGGVTRMGPELVWQLDMLFRTAAEHGLDIDLHVDETDDRGA
ETLKAIAEAVLRNGFEGKVTAGHCCSLARQDEDTAARTVELVAKAGIAVIALPMCNMYLQDRYPGRTPRWRGVTLFKELV
AAGVATAVASDNTRDPFYAYGDLDPVEVFREAVRILHLDHPLDTAARVVTTSPAAIVGRPDKGRIAAGDPADLVLFSARR
WSEFLSRPQSDRVVLRRGKVIDRSLPDYRELDSVVGA

Sequences:

>Translated_437_residues
MTYSFISPPNAARFVLSNATVPAVTVEHIDVPVTEGLATVDIVISDGMIAAIRPAGAAPADYARTDLRDGMVWPCFADIH
THLDKGHIWPRQANPDGSFMGALDAVRADREANWSAADVKRRMEFSLRSAHAHGTSLIRTHLDSLAPQHRISFEVFAEIR
DAWKDRIALQAVALFPLDAMADSAFFADLVTTIRQTGGLLGGVTRMGPELVWQLDMLFRTAAEHGLDIDLHVDETDDRGA
ETLKAIAEAVLRNGFEGKVTAGHCCSLARQDEDTAARTVELVAKAGIAVIALPMCNMYLQDRYPGRTPRWRGVTLFKELV
AAGVATAVASDNTRDPFYAYGDLDPVEVFREAVRILHLDHPLDTAARVVTTSPAAIVGRPDKGRIAAGDPADLVLFSARR
WSEFLSRPQSDRVVLRRGKVIDRSLPDYRELDSVVGA
>Mature_436_residues
TYSFISPPNAARFVLSNATVPAVTVEHIDVPVTEGLATVDIVISDGMIAAIRPAGAAPADYARTDLRDGMVWPCFADIHT
HLDKGHIWPRQANPDGSFMGALDAVRADREANWSAADVKRRMEFSLRSAHAHGTSLIRTHLDSLAPQHRISFEVFAEIRD
AWKDRIALQAVALFPLDAMADSAFFADLVTTIRQTGGLLGGVTRMGPELVWQLDMLFRTAAEHGLDIDLHVDETDDRGAE
TLKAIAEAVLRNGFEGKVTAGHCCSLARQDEDTAARTVELVAKAGIAVIALPMCNMYLQDRYPGRTPRWRGVTLFKELVA
AGVATAVASDNTRDPFYAYGDLDPVEVFREAVRILHLDHPLDTAARVVTTSPAAIVGRPDKGRIAAGDPADLVLFSARRW
SEFLSRPQSDRVVLRRGKVIDRSLPDYRELDSVVGA

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=410, Percent_Identity=26.5853658536585, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 47738; Mature: 47607

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00134 TRYPSIN_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYSFISPPNAARFVLSNATVPAVTVEHIDVPVTEGLATVDIVISDGMIAAIRPAGAAPA
CCCCCCCCCCCCEEEEECCCCCEEEEEECCCCHHCCCEEEEEEEECCEEEEECCCCCCCH
DYARTDLRDGMVWPCFADIHTHLDKGHIWPRQANPDGSFMGALDAVRADREANWSAADVK
HHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHH
RRMEFSLRSAHAHGTSLIRTHLDSLAPQHRISFEVFAEIRDAWKDRIALQAVALFPLDAM
HHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ADSAFFADLVTTIRQTGGLLGGVTRMGPELVWQLDMLFRTAAEHGLDIDLHVDETDDRGA
HHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHH
ETLKAIAEAVLRNGFEGKVTAGHCCSLARQDEDTAARTVELVAKAGIAVIALPMCNMYLQ
HHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCHHEEEHHHHHHHHH
DRYPGRTPRWRGVTLFKELVAAGVATAVASDNTRDPFYAYGDLDPVEVFREAVRILHLDH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCC
PLDTAARVVTTSPAAIVGRPDKGRIAAGDPADLVLFSARRWSEFLSRPQSDRVVLRRGKV
CHHHHHHEEECCCCEEEECCCCCCEECCCCHHEEEECHHHHHHHHCCCCCCCCHHHCCCH
IDRSLPDYRELDSVVGA
HHCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TYSFISPPNAARFVLSNATVPAVTVEHIDVPVTEGLATVDIVISDGMIAAIRPAGAAPA
CCCCCCCCCCCEEEEECCCCCEEEEEECCCCHHCCCEEEEEEEECCEEEEECCCCCCCH
DYARTDLRDGMVWPCFADIHTHLDKGHIWPRQANPDGSFMGALDAVRADREANWSAADVK
HHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHH
RRMEFSLRSAHAHGTSLIRTHLDSLAPQHRISFEVFAEIRDAWKDRIALQAVALFPLDAM
HHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ADSAFFADLVTTIRQTGGLLGGVTRMGPELVWQLDMLFRTAAEHGLDIDLHVDETDDRGA
HHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHH
ETLKAIAEAVLRNGFEGKVTAGHCCSLARQDEDTAARTVELVAKAGIAVIALPMCNMYLQ
HHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCHHEEEHHHHHHHHH
DRYPGRTPRWRGVTLFKELVAAGVATAVASDNTRDPFYAYGDLDPVEVFREAVRILHLDH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCC
PLDTAARVVTTSPAAIVGRPDKGRIAAGDPADLVLFSARRWSEFLSRPQSDRVVLRRGKV
CHHHHHHEEECCCCEEEECCCCCCEECCCCHHEEEECHHHHHHHHCCCCCCCCHHHCCCH
IDRSLPDYRELDSVVGA
HHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]