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The map label for this gene is glcD [C]

Identifier: 116248978

GI number: 116248978

Start: 327454

End: 328863

Strand: Direct

Name: glcD [C]

Synonym: pRL120309

Alternate gene names: 116248978

Gene position: 327454-328863 (Clockwise)

Preceding gene: 116248977

Following gene: 116248979

Centisome position: 37.64

GC content: 61.35

Gene sequence:

>1410_bases
ATGGCCGATTATCAGAAGATCAAAAAGGACCTCGAAGGCATCGCTGTCGAGGACAATCCGGCGCTGGTTCGCCAGAAGAG
CCGGGATTTCTATTGGTACTCGCCGATCCTGAAGGCGCAGCTCGACAATGTTTCCGCCGATCTCGTCGTCACGCCGAAGA
CCGAGGAAGAGGTCATCCGGACGCTGAAGGTCGCCTATGCCCATGGCGTGCCGGTCACGCCGCGCGGCGCCGGCACCGGC
AATTACGGCCAGGCCATGCCGCTTTCCGGCGGCATCGTGCTGAACCTTGCAGCTATGGACAAGATCAAAGAGATCCATCC
CGGCCGCGTCGTCTGCGAACCGGGCATCGTACTTGCCCAACTCGACAAGCAGACCAAGGCCCATTCCGGCCAGGAGCTGC
GCTTCCACCCCTCCACCGCCCAAACGGCGACGGTCGGCGGCTTCATTGCCGGCGGCTCGGGCGGCGTCGGCTCGATCACC
TGGGGCGGCTTGCGCGACCTCGGCAATATCCTGCGCCTGCGCGTCGTCACGATGGAGGCCGAACCGCGCGTGCTCGACCT
CACCGGCTGGGATCTCCAGAAGGTGAGCCACGCCTACGGCACCAACGGTATCATCACCGAGATCGAGATGCCGCTTGCGC
CTGCCTATGACTGGGTCGATGTGCTCGTCGGCTATGACGACTTCATGGAAGCGGTGCGCTTTTCCGACGCGCTGGCGAAA
TGCAACGGCATCCTCGTCAAGGAGATCGCGCCGATCGCCGCTCCCATCCCTTACGACTATTTCACCCGCCACAAGCCCTA
CATCCGTCAGGGCCAGTCGATTGTCGTGCTGATGATCGCGCCGCACTCCATGGATGCCTTTCTTGCCTTCACGGCGGCGC
AGAAGGGCGAGATCATGTTCCGCTCCGACAAGGTGGAAAGCATGCGCGGCATCCCGCACGCCTATGAGCTTGCCTGGAAC
CACACGACACTGCGTGCGCTGAAGGTCGACCCGAGCTTCACCTATCTGCAGGTGCAATATCCTGGACCCGATCATGTCGC
CAAGGTCCGCAAGATGGTGGAGATCTTCGGTGACGAAGTGCCGGGTCATCTCGAATTCATCAAATTCGACGGCCAGATCC
AGTGCTCGGGCCTGCCGCTGGTGCGCTATACCACCGAGGAGCGGCTGGAGGAGATCATCAAGATCCACCAGGATAATGGA
TGCCCGATCTTCAACCCGCACCGCTATACGCTCGAAGAAGGCGGCATGAAGCGGACCGATGCGGTGCAACTCGCCTTCAA
GCAGGAAACCGATCCGAAGGGCCTGCTCAATCCCGGCAAGATGATCGCCTGGGAAAATCCCGATTTCGATTTCAACGCCG
GCAAGAACTATCTCTTCCCCGGCCTGGCGGCCCTGATGGAGGCCTCATGA

Upstream 100 bases:

>100_bases
TCCCGTCCGCAGTCTGACCGCGTCGTGCTTCGCCGCGGCAAGGTGATCGACCGCAGTCTGCCGGATTACCGTGAACTCGA
TAGTGTCGTTGGAGCCTGAC

Downstream 100 bases:

>100_bases
GGGTTCTCGTCCTCCACTCTCACCCGGTCGAGGAAAGTTATGGCAAGGCGCTTTACCGGCAAACCGTCGAGAGCCTGCAG
AAGGCCGGGCATATGGTGGA

Product: putative FAD-binding dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MADYQKIKKDLEGIAVEDNPALVRQKSRDFYWYSPILKAQLDNVSADLVVTPKTEEEVIRTLKVAYAHGVPVTPRGAGTG
NYGQAMPLSGGIVLNLAAMDKIKEIHPGRVVCEPGIVLAQLDKQTKAHSGQELRFHPSTAQTATVGGFIAGGSGGVGSIT
WGGLRDLGNILRLRVVTMEAEPRVLDLTGWDLQKVSHAYGTNGIITEIEMPLAPAYDWVDVLVGYDDFMEAVRFSDALAK
CNGILVKEIAPIAAPIPYDYFTRHKPYIRQGQSIVVLMIAPHSMDAFLAFTAAQKGEIMFRSDKVESMRGIPHAYELAWN
HTTLRALKVDPSFTYLQVQYPGPDHVAKVRKMVEIFGDEVPGHLEFIKFDGQIQCSGLPLVRYTTEERLEEIIKIHQDNG
CPIFNPHRYTLEEGGMKRTDAVQLAFKQETDPKGLLNPGKMIAWENPDFDFNAGKNYLFPGLAALMEAS

Sequences:

>Translated_469_residues
MADYQKIKKDLEGIAVEDNPALVRQKSRDFYWYSPILKAQLDNVSADLVVTPKTEEEVIRTLKVAYAHGVPVTPRGAGTG
NYGQAMPLSGGIVLNLAAMDKIKEIHPGRVVCEPGIVLAQLDKQTKAHSGQELRFHPSTAQTATVGGFIAGGSGGVGSIT
WGGLRDLGNILRLRVVTMEAEPRVLDLTGWDLQKVSHAYGTNGIITEIEMPLAPAYDWVDVLVGYDDFMEAVRFSDALAK
CNGILVKEIAPIAAPIPYDYFTRHKPYIRQGQSIVVLMIAPHSMDAFLAFTAAQKGEIMFRSDKVESMRGIPHAYELAWN
HTTLRALKVDPSFTYLQVQYPGPDHVAKVRKMVEIFGDEVPGHLEFIKFDGQIQCSGLPLVRYTTEERLEEIIKIHQDNG
CPIFNPHRYTLEEGGMKRTDAVQLAFKQETDPKGLLNPGKMIAWENPDFDFNAGKNYLFPGLAALMEAS
>Mature_468_residues
ADYQKIKKDLEGIAVEDNPALVRQKSRDFYWYSPILKAQLDNVSADLVVTPKTEEEVIRTLKVAYAHGVPVTPRGAGTGN
YGQAMPLSGGIVLNLAAMDKIKEIHPGRVVCEPGIVLAQLDKQTKAHSGQELRFHPSTAQTATVGGFIAGGSGGVGSITW
GGLRDLGNILRLRVVTMEAEPRVLDLTGWDLQKVSHAYGTNGIITEIEMPLAPAYDWVDVLVGYDDFMEAVRFSDALAKC
NGILVKEIAPIAAPIPYDYFTRHKPYIRQGQSIVVLMIAPHSMDAFLAFTAAQKGEIMFRSDKVESMRGIPHAYELAWNH
TTLRALKVDPSFTYLQVQYPGPDHVAKVRKMVEIFGDEVPGHLEFIKFDGQIQCSGLPLVRYTTEERLEEIIKIHQDNGC
PIFNPHRYTLEEGGMKRTDAVQLAFKQETDPKGLLNPGKMIAWENPDFDFNAGKNYLFPGLAALMEAS

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=181, Percent_Identity=32.5966850828729, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI37595754, Length=132, Percent_Identity=36.3636363636364, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI119964728, Length=213, Percent_Identity=28.169014084507, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789351, Length=208, Percent_Identity=31.25, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320764, Length=177, Percent_Identity=26.5536723163842, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320023, Length=180, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 51882; Mature: 51751

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADYQKIKKDLEGIAVEDNPALVRQKSRDFYWYSPILKAQLDNVSADLVVTPKTEEEVIR
CCCHHHHHHHHCCEEECCCCHHHHCCCCCEEEECHHHHHHHCCCCCCEEECCCCHHHHHH
TLKVAYAHGVPVTPRGAGTGNYGQAMPLSGGIVLNLAAMDKIKEIHPGRVVCEPGIVLAQ
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCEEEECCCEEEEE
LDKQTKAHSGQELRFHPSTAQTATVGGFIAGGSGGVGSITWGGLRDLGNILRLRVVTMEA
CCHHHHHCCCCEEEECCCCCCEEECCCEEECCCCCCCCCCCCCHHHHHHEEEEEEEEEEC
EPRVLDLTGWDLQKVSHAYGTNGIITEIEMPLAPAYDWVDVLVGYDDFMEAVRFSDALAK
CCCEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCHHHHHHHHHHHHHHHH
CNGILVKEIAPIAAPIPYDYFTRHKPYIRQGQSIVVLMIAPHSMDAFLAFTAAQKGEIMF
HCCEEEEHHCHHCCCCCCHHHHCCCCHHHCCCEEEEEEEECCCCCEEEEEEECCCCCEEE
RSDKVESMRGIPHAYELAWNHTTLRALKVDPSFTYLQVQYPGPDHVAKVRKMVEIFGDEV
ECCCHHHHHCCCCCEEEEECCEEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHCCCC
PGHLEFIKFDGQIQCSGLPLVRYTTEERLEEIIKIHQDNGCPIFNPHRYTLEEGGMKRTD
CCCEEEEEECCEEEECCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCH
AVQLAFKQETDPKGLLNPGKMIAWENPDFDFNAGKNYLFPGLAALMEAS
HEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
ADYQKIKKDLEGIAVEDNPALVRQKSRDFYWYSPILKAQLDNVSADLVVTPKTEEEVIR
CCHHHHHHHHCCEEECCCCHHHHCCCCCEEEECHHHHHHHCCCCCCEEECCCCHHHHHH
TLKVAYAHGVPVTPRGAGTGNYGQAMPLSGGIVLNLAAMDKIKEIHPGRVVCEPGIVLAQ
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCEEEECCCEEEEE
LDKQTKAHSGQELRFHPSTAQTATVGGFIAGGSGGVGSITWGGLRDLGNILRLRVVTMEA
CCHHHHHCCCCEEEECCCCCCEEECCCEEECCCCCCCCCCCCCHHHHHHEEEEEEEEEEC
EPRVLDLTGWDLQKVSHAYGTNGIITEIEMPLAPAYDWVDVLVGYDDFMEAVRFSDALAK
CCCEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCHHHHHHHHHHHHHHHH
CNGILVKEIAPIAAPIPYDYFTRHKPYIRQGQSIVVLMIAPHSMDAFLAFTAAQKGEIMF
HCCEEEEHHCHHCCCCCCHHHHCCCCHHHCCCEEEEEEEECCCCCEEEEEEECCCCCEEE
RSDKVESMRGIPHAYELAWNHTTLRALKVDPSFTYLQVQYPGPDHVAKVRKMVEIFGDEV
ECCCHHHHHCCCCCEEEEECCEEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHCCCC
PGHLEFIKFDGQIQCSGLPLVRYTTEERLEEIIKIHQDNGCPIFNPHRYTLEEGGMKRTD
CCCEEEEEECCEEEECCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCH
AVQLAFKQETDPKGLLNPGKMIAWENPDFDFNAGKNYLFPGLAALMEAS
HEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]