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The map label for this gene is gsiC [H]

Identifier: 116248835

GI number: 116248835

Start: 162803

End: 163783

Strand: Reverse

Name: gsiC [H]

Synonym: pRL120163

Alternate gene names: 116248835

Gene position: 163783-162803 (Counterclockwise)

Preceding gene: 116248836

Following gene: 116248834

Centisome position: 18.83

GC content: 60.75

Gene sequence:

>981_bases
ATGTTCATTCTCAGTTTTCTGGTTCGACGGCTGGCGCAAGGCGCATTGATCGTTTTTCTGGTGACGCTGCTGATCTTCAC
GCTGCTGCGTGTGGTTCCCGGCGATCCGGTCCGGCTGATGGCCGGCGGCATGGCGCCAGAAGCGCTGATCGAGCAGATCG
CCAAGGACATGGGCCTGCGTGATCCCATCCTCGTGCAGTTCGGCCGCTATATGAGCGGCGTCGTCAGGGGCGATCTCGGA
CAATCCTTCGTACGGCCTGCGAGCGGCGCTTCTACAGGCGGCTCCAGCTTCGGCGATTCCACTCGCGGCGAACGGGCCGA
AGTGCTGACCCTGATCGCCGACACCCTGCCGATGACGCTGCAACTCGGCGGACTGGCAATATTCTTCGCCCTGGTCTTCT
CGTTCCTGGTCGGCATTCCCGGCGGACTGGCGCCTGGACGATGGCCGGATCGCGTGGCCTTCTACATTTCCTCGATCTTC
ATATCGTTGCCGAACTTCTGGCTCGGCATCGTCCTTGCCATGCTTTTGTCGGTCAAGCTCGGCTGGCTGCCTGCGATCGG
CTATTCCGGCTTTGCCTATACCATCCTCCCGGCGATCGTTCTGGCCGTCGAACTGGCGCCGGTGCTGATCCGGACGCTGA
CCGGATCCGTGGCTACCGTGATGATGGAGCCCTTCATCGCAGTCGGCAATGTCCGCGGCCTTAGTCGCAGCCGCATCATC
GTTGCCCATGCGCTACGCAATGCGTCCGTTCCGCTGCTCAATCTGATCGGCATCCAGATCAGCGGCCTGCTGGGTGGCGT
CCTCGTCGTCGAATTCATCTTCGACTATCCGGGCCTCGGCCTTTTGACCATCAACGCCGTGCTGCAGCGTGACTTCCCGC
TCATCCAAGGGATCGCCATCGTCACCAGCGCGATCTTCGTCTTCATCAACATCGCAGTCGACCTGATTGCCACCATGATC
GATCCAAGGTTGGAATATTGA

Upstream 100 bases:

>100_bases
GCCGGCGCCGCGGAGGTTTTCGTTTCGCTCATGATGTCAACAAACGACCGCGACCGTCACCGCTCAGGACGGTTCGCTCC
GATTGCTGCCAGGATATGAC

Downstream 100 bases:

>100_bases
TGAGCGTGACAGAGACAGACATCCCGGCAGTCCCGGTTCCGGCAACGCAACGCGGCGCTTCGGTGGCGCGGCGTATCTGG
CGGATTGCCCTTGCCTCCAA

Product: putative permease component of ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MFILSFLVRRLAQGALIVFLVTLLIFTLLRVVPGDPVRLMAGGMAPEALIEQIAKDMGLRDPILVQFGRYMSGVVRGDLG
QSFVRPASGASTGGSSFGDSTRGERAEVLTLIADTLPMTLQLGGLAIFFALVFSFLVGIPGGLAPGRWPDRVAFYISSIF
ISLPNFWLGIVLAMLLSVKLGWLPAIGYSGFAYTILPAIVLAVELAPVLIRTLTGSVATVMMEPFIAVGNVRGLSRSRII
VAHALRNASVPLLNLIGIQISGLLGGVLVVEFIFDYPGLGLLTINAVLQRDFPLIQGIAIVTSAIFVFINIAVDLIATMI
DPRLEY

Sequences:

>Translated_326_residues
MFILSFLVRRLAQGALIVFLVTLLIFTLLRVVPGDPVRLMAGGMAPEALIEQIAKDMGLRDPILVQFGRYMSGVVRGDLG
QSFVRPASGASTGGSSFGDSTRGERAEVLTLIADTLPMTLQLGGLAIFFALVFSFLVGIPGGLAPGRWPDRVAFYISSIF
ISLPNFWLGIVLAMLLSVKLGWLPAIGYSGFAYTILPAIVLAVELAPVLIRTLTGSVATVMMEPFIAVGNVRGLSRSRII
VAHALRNASVPLLNLIGIQISGLLGGVLVVEFIFDYPGLGLLTINAVLQRDFPLIQGIAIVTSAIFVFINIAVDLIATMI
DPRLEY
>Mature_326_residues
MFILSFLVRRLAQGALIVFLVTLLIFTLLRVVPGDPVRLMAGGMAPEALIEQIAKDMGLRDPILVQFGRYMSGVVRGDLG
QSFVRPASGASTGGSSFGDSTRGERAEVLTLIADTLPMTLQLGGLAIFFALVFSFLVGIPGGLAPGRWPDRVAFYISSIF
ISLPNFWLGIVLAMLLSVKLGWLPAIGYSGFAYTILPAIVLAVELAPVLIRTLTGSVATVMMEPFIAVGNVRGLSRSRII
VAHALRNASVPLLNLIGIQISGLLGGVLVVEFIFDYPGLGLLTINAVLQRDFPLIQGIAIVTSAIFVFINIAVDLIATMI
DPRLEY

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=324, Percent_Identity=34.2592592592593, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1789888, Length=327, Percent_Identity=32.1100917431193, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789965, Length=357, Percent_Identity=31.6526610644258, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1787497, Length=326, Percent_Identity=27.9141104294479, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1787761, Length=353, Percent_Identity=29.4617563739377, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787550, Length=242, Percent_Identity=29.7520661157025, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788504, Length=308, Percent_Identity=26.6233766233766, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34870; Mature: 34870

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFILSFLVRRLAQGALIVFLVTLLIFTLLRVVPGDPVRLMAGGMAPEALIEQIAKDMGLR
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHCCCC
DPILVQFGRYMSGVVRGDLGQSFVRPASGASTGGSSFGDSTRGERAEVLTLIADTLPMTL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QLGGLAIFFALVFSFLVGIPGGLAPGRWPDRVAFYISSIFISLPNFWLGIVLAMLLSVKL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GWLPAIGYSGFAYTILPAIVLAVELAPVLIRTLTGSVATVMMEPFIAVGNVRGLSRSRII
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
VAHALRNASVPLLNLIGIQISGLLGGVLVVEFIFDYPGLGLLTINAVLQRDFPLIQGIAI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHH
VTSAIFVFINIAVDLIATMIDPRLEY
HHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFILSFLVRRLAQGALIVFLVTLLIFTLLRVVPGDPVRLMAGGMAPEALIEQIAKDMGLR
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHCCCC
DPILVQFGRYMSGVVRGDLGQSFVRPASGASTGGSSFGDSTRGERAEVLTLIADTLPMTL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QLGGLAIFFALVFSFLVGIPGGLAPGRWPDRVAFYISSIFISLPNFWLGIVLAMLLSVKL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GWLPAIGYSGFAYTILPAIVLAVELAPVLIRTLTGSVATVMMEPFIAVGNVRGLSRSRII
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
VAHALRNASVPLLNLIGIQISGLLGGVLVVEFIFDYPGLGLLTINAVLQRDFPLIQGIAI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHH
VTSAIFVFINIAVDLIATMIDPRLEY
HHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]