Click here to switch to the map view.

The map label for this gene is appC [H]

Identifier: 116248834

GI number: 116248834

Start: 161880

End: 162806

Strand: Reverse

Name: appC [H]

Synonym: pRL120162

Alternate gene names: 116248834

Gene position: 162806-161880 (Counterclockwise)

Preceding gene: 116248835

Following gene: 116248833

Centisome position: 18.71

GC content: 62.03

Gene sequence:

>927_bases
TTGATGAGCGTGACAGAGACAGACATCCCGGCAGTCCCGGTTCCGGCAACGCAACGCGGCGCTTCGGTGGCGCGGCGTAT
CTGGCGGATTGCCCTTGCCTCCAACGAATTTCGTTTCGGCGCTGCCATTTTCATCGTGCTGGTTCTGGCGGCCCTGCTTT
ATCCGGAATTGAGCGGTATCGACCCCACGAAGATGAGTGTCGCCACACGCTTGCATGCGCCGCCGTTCATGGGCGAAAAA
TGGAGCTGGACGGCGCCGCTCGGCACCGACCAGATCGGACGCGACATGTTGGTGCGCAGCCTTGTCGGTCTGCGTTACTC
GTTGCTGATCGGGCTTTCCACCGTTCTCGTCATGCTGATCATCGGCTGTTCGCTCGGCACGATCGCCGGCTACTATGGCG
GCCGCGTCGACATGGTGATCATGCGCCTGACCGATGCCCAGCTGTCGATCCCGATGATTATTCTGGCCATCACCGTGCTC
GGAGTCTCGCGCCCGACGATCCCCGCGATCATCCTCGTCCTCGGCCTTTCGAGCTGGCCAGTCTATGCCCGCGTCACCCG
CAGCGTCGTGATGACCGAGCGCAAGCGGGAATATGTGCGCGCCGCCGAAATCTACGGCGCATCGGATTTCCGCATCATGG
TGCGCCTGCTGGCGCCCTTGGTGCTGCCGCCGATCATCTTCGTGTCGGTGCTCGATGTCGCCCGGATGATGATCTTCGAA
TCCATCCTCGGCTTCATCGGGCTGGGCGTTCAGCCGCCGACGCCGACTTTCGGCAACATCATCGCCGACGGCCGCAAATA
CCTGCTCAACGCCTGGTGGATCGCCACCATGCCGGGCGTGTTCCTGTGTCTGTGCCTGACCAGCATCAACCTGATGGGCG
CGTCGCTCGAACGGGCTCGCAATCGTATCTATGGAGGCAAATCGTGA

Upstream 100 bases:

>100_bases
CGCTCATCCAAGGGATCGCCATCGTCACCAGCGCGATCTTCGTCTTCATCAACATCGCAGTCGACCTGATTGCCACCATG
ATCGATCCAAGGTTGGAATA

Downstream 100 bases:

>100_bases
CCGGCACACCGCTTCTGAAGGTTCGCGATCTGAGCGTCGGCCTGGAAACGGGCGGCGGCATGCGCCCGATCATTTCCGAC
ATCGGCTTCGATCTGGCCCC

Product: putative permease component of ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MMSVTETDIPAVPVPATQRGASVARRIWRIALASNEFRFGAAIFIVLVLAALLYPELSGIDPTKMSVATRLHAPPFMGEK
WSWTAPLGTDQIGRDMLVRSLVGLRYSLLIGLSTVLVMLIIGCSLGTIAGYYGGRVDMVIMRLTDAQLSIPMIILAITVL
GVSRPTIPAIILVLGLSSWPVYARVTRSVVMTERKREYVRAAEIYGASDFRIMVRLLAPLVLPPIIFVSVLDVARMMIFE
SILGFIGLGVQPPTPTFGNIIADGRKYLLNAWWIATMPGVFLCLCLTSINLMGASLERARNRIYGGKS

Sequences:

>Translated_308_residues
MMSVTETDIPAVPVPATQRGASVARRIWRIALASNEFRFGAAIFIVLVLAALLYPELSGIDPTKMSVATRLHAPPFMGEK
WSWTAPLGTDQIGRDMLVRSLVGLRYSLLIGLSTVLVMLIIGCSLGTIAGYYGGRVDMVIMRLTDAQLSIPMIILAITVL
GVSRPTIPAIILVLGLSSWPVYARVTRSVVMTERKREYVRAAEIYGASDFRIMVRLLAPLVLPPIIFVSVLDVARMMIFE
SILGFIGLGVQPPTPTFGNIIADGRKYLLNAWWIATMPGVFLCLCLTSINLMGASLERARNRIYGGKS
>Mature_308_residues
MMSVTETDIPAVPVPATQRGASVARRIWRIALASNEFRFGAAIFIVLVLAALLYPELSGIDPTKMSVATRLHAPPFMGEK
WSWTAPLGTDQIGRDMLVRSLVGLRYSLLIGLSTVLVMLIIGCSLGTIAGYYGGRVDMVIMRLTDAQLSIPMIILAITVL
GVSRPTIPAIILVLGLSSWPVYARVTRSVVMTERKREYVRAAEIYGASDFRIMVRLLAPLVLPPIIFVSVLDVARMMIFE
SILGFIGLGVQPPTPTFGNIIADGRKYLLNAWWIATMPGVFLCLCLTSINLMGASLERARNRIYGGKS

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=295, Percent_Identity=32.8813559322034, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1789964, Length=299, Percent_Identity=34.7826086956522, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1789889, Length=241, Percent_Identity=34.8547717842324, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1787054, Length=260, Percent_Identity=30.3846153846154, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787498, Length=282, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787549, Length=217, Percent_Identity=33.1797235023041, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788505, Length=212, Percent_Identity=29.7169811320755, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33655; Mature: 33655

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSVTETDIPAVPVPATQRGASVARRIWRIALASNEFRFGAAIFIVLVLAALLYPELSGI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
DPTKMSVATRLHAPPFMGEKWSWTAPLGTDQIGRDMLVRSLVGLRYSLLIGLSTVLVMLI
CCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGCSLGTIAGYYGGRVDMVIMRLTDAQLSIPMIILAITVLGVSRPTIPAIILVLGLSSWP
HHCCHHHHHHHCCCHHEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
VYARVTRSVVMTERKREYVRAAEIYGASDFRIMVRLLAPLVLPPIIFVSVLDVARMMIFE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILGFIGLGVQPPTPTFGNIIADGRKYLLNAWWIATMPGVFLCLCLTSINLMGASLERAR
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRIYGGKS
HHCCCCCC
>Mature Secondary Structure
MMSVTETDIPAVPVPATQRGASVARRIWRIALASNEFRFGAAIFIVLVLAALLYPELSGI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
DPTKMSVATRLHAPPFMGEKWSWTAPLGTDQIGRDMLVRSLVGLRYSLLIGLSTVLVMLI
CCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGCSLGTIAGYYGGRVDMVIMRLTDAQLSIPMIILAITVLGVSRPTIPAIILVLGLSSWP
HHCCHHHHHHHCCCHHEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
VYARVTRSVVMTERKREYVRAAEIYGASDFRIMVRLLAPLVLPPIIFVSVLDVARMMIFE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILGFIGLGVQPPTPTFGNIIADGRKYLLNAWWIATMPGVFLCLCLTSINLMGASLERAR
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRIYGGKS
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]