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The map label for this gene is gbpR [H]

Identifier: 116248778

GI number: 116248778

Start: 97984

End: 98934

Strand: Direct

Name: gbpR [H]

Synonym: pRL120102

Alternate gene names: 116248778

Gene position: 97984-98934 (Clockwise)

Preceding gene: 116248768

Following gene: 116248780

Centisome position: 11.26

GC content: 62.67

Gene sequence:

>951_bases
ATGAAGATAGACGAACGTCACCTTATCCAGCTTGCGGCAGTCGTCAAAACCGGCGGGGTCACCGAGGGAGCGGCCCTGCT
CGGCCTATCGCAGCCGGCTGTTTCGCGCACGCTCTCGATGCTCGAGGCTCGCATCGGCGAACCGCTGTTCCTCAAAGGGC
GACGGCCGCTGCAGCCAACGCCATTGGGACGAGCGCTGGCCGATCACGGTCAGACTATGCTGTCGGCATCGCGCAAGGCC
TCTGATGTCGTCGAAAGCTTTCGGGCCGGCCGAAGCGGCGTGGTGCGCGTCGGTGGTACGCCTTTTTTCATGGATGCGTT
GATCGCGGGGATGATCGCCGAGTTCCAGAACCTGCATCCAGACGTGCGCATCGACCAGACCTATGGTTATTTTCCAGACC
TCCGTGCCGCGCTCAATGCCGACCAGATCGACCTTGCCATCTGTCCGATCGATATTCTCGACGAGGGCTCCGGCCTTGAA
TTTCAGCAGATCCTGCCCGGCCGCAACGTCGTCGCCTGCCGGGTCACCCATCCTTTGCTGTTGAAGCGGCGACCTCAGCC
GGCGCACCTGCTCGATTTTCCTTGGGTGGCGCCCCCGCCAGGCAGCCCGCTACTCACCGATCTGCGCAGCATGCTGCTGT
CTTTCGGCGCAACCGAAGTCAAGATTCGCTATTCGGGCGGCTCCCTCATGAGCGTCGTCCACTACATGAAGGCGGCTGAT
GCGCTGACCATCATGCCGCACAGCGTCGTCTTCGCATTGCGCAACGAAAAGTCCATCACCGCCCTGCCCGTCCCCATCCC
CCATTCGGAACGCGCGCTCGGTTTGCTGAAGCGTTCGGACGCACCCCGCACGCCCGCCGCCGATCACTTCGCCCGCCACA
TCCGCACAGGCTTCGATAACCTCAAGCATCTGATCAAGCGGCACGAGCAGTCAGTGGTCTGGGGAGCCTAG

Upstream 100 bases:

>100_bases
GTCATGCGTCTCCTCCAAGGCAATGGCTGGTGGAGACAAATTTAGTCCAATCGCTATATGCCGGTAATGATTTTATTCGC
GATTAATATATCATATCGTT

Downstream 100 bases:

>100_bases
ACGCTAGTTTCCCGGCGAGTGACCCATGAGCGTCGCCGCCGGGGCATATGCGGGTCGCGTGGGCGAGTGGGTTGGCGACA
TTTGCAGTTCCTGACCGTCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKIDERHLIQLAAVVKTGGVTEGAALLGLSQPAVSRTLSMLEARIGEPLFLKGRRPLQPTPLGRALADHGQTMLSASRKA
SDVVESFRAGRSGVVRVGGTPFFMDALIAGMIAEFQNLHPDVRIDQTYGYFPDLRAALNADQIDLAICPIDILDEGSGLE
FQQILPGRNVVACRVTHPLLLKRRPQPAHLLDFPWVAPPPGSPLLTDLRSMLLSFGATEVKIRYSGGSLMSVVHYMKAAD
ALTIMPHSVVFALRNEKSITALPVPIPHSERALGLLKRSDAPRTPAADHFARHIRTGFDNLKHLIKRHEQSVVWGA

Sequences:

>Translated_316_residues
MKIDERHLIQLAAVVKTGGVTEGAALLGLSQPAVSRTLSMLEARIGEPLFLKGRRPLQPTPLGRALADHGQTMLSASRKA
SDVVESFRAGRSGVVRVGGTPFFMDALIAGMIAEFQNLHPDVRIDQTYGYFPDLRAALNADQIDLAICPIDILDEGSGLE
FQQILPGRNVVACRVTHPLLLKRRPQPAHLLDFPWVAPPPGSPLLTDLRSMLLSFGATEVKIRYSGGSLMSVVHYMKAAD
ALTIMPHSVVFALRNEKSITALPVPIPHSERALGLLKRSDAPRTPAADHFARHIRTGFDNLKHLIKRHEQSVVWGA
>Mature_316_residues
MKIDERHLIQLAAVVKTGGVTEGAALLGLSQPAVSRTLSMLEARIGEPLFLKGRRPLQPTPLGRALADHGQTMLSASRKA
SDVVESFRAGRSGVVRVGGTPFFMDALIAGMIAEFQNLHPDVRIDQTYGYFPDLRAALNADQIDLAICPIDILDEGSGLE
FQQILPGRNVVACRVTHPLLLKRRPQPAHLLDFPWVAPPPGSPLLTDLRSMLLSFGATEVKIRYSGGSLMSVVHYMKAAD
ALTIMPHSVVFALRNEKSITALPVPIPHSERALGLLKRSDAPRTPAADHFARHIRTGFDNLKHLIKRHEQSVVWGA

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=275, Percent_Identity=21.8181818181818, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081904, Length=298, Percent_Identity=25.8389261744966, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789204, Length=185, Percent_Identity=30.2702702702703, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI145693105, Length=297, Percent_Identity=20.5387205387205, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34477; Mature: 34477

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDERHLIQLAAVVKTGGVTEGAALLGLSQPAVSRTLSMLEARIGEPLFLKGRRPLQPT
CCCCHHHHHHHHHHHHCCCCCCCHHHEECCCHHHHHHHHHHHHHCCCCEEECCCCCCCCC
PLGRALADHGQTMLSASRKASDVVESFRAGRSGVVRVGGTPFFMDALIAGMIAEFQNLHP
CCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCC
DVRIDQTYGYFPDLRAALNADQIDLAICPIDILDEGSGLEFQQILPGRNVVACRVTHPLL
CEEECCCCCCCCHHHHHCCCCCEEEEECCHHEECCCCCCCHHHHCCCCCEEEEEECCHHH
LKRRPQPAHLLDFPWVAPPPGSPLLTDLRSMLLSFGATEVKIRYSGGSLMSVVHYMKAAD
HCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHC
ALTIMPHSVVFALRNEKSITALPVPIPHSERALGLLKRSDAPRTPAADHFARHIRTGFDN
CEEECCHHEEEEEECCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LKHLIKRHEQSVVWGA
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIDERHLIQLAAVVKTGGVTEGAALLGLSQPAVSRTLSMLEARIGEPLFLKGRRPLQPT
CCCCHHHHHHHHHHHHCCCCCCCHHHEECCCHHHHHHHHHHHHHCCCCEEECCCCCCCCC
PLGRALADHGQTMLSASRKASDVVESFRAGRSGVVRVGGTPFFMDALIAGMIAEFQNLHP
CCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCC
DVRIDQTYGYFPDLRAALNADQIDLAICPIDILDEGSGLEFQQILPGRNVVACRVTHPLL
CEEECCCCCCCCHHHHHCCCCCEEEEECCHHEECCCCCCCHHHHCCCCCEEEEEECCHHH
LKRRPQPAHLLDFPWVAPPPGSPLLTDLRSMLLSFGATEVKIRYSGGSLMSVVHYMKAAD
HCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHC
ALTIMPHSVVFALRNEKSITALPVPIPHSERALGLLKRSDAPRTPAADHFARHIRTGFDN
CEEECCHHEEEEEECCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LKHLIKRHEQSVVWGA
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]